About: PD 158771, a potential antipsychotic agent with D(2)/D(3) partial agonist and 5-HT(1A) agonist actions. I. Neurochemical effects

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About: PD 158771, a potential antipsychotic agent with D(2)/D(3) partial agonist and 5-HT(1A) agonist actions. I. Neurochemical effects Goto Sponge NotDistinct Permalink

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scientific article published on 01 April 2000

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description	wetenschappelijk artikel (nl) wüsseschaftlicher Artikel, wo im April 2000 veröffentlicht worden isch (gsw) наукова стаття, опублікована у квітні 2000 (uk) im April 2000 veröffentlichter wissenschaftlicher Artikel (de) article scientifique publié en avril 2000 (fr) artículu científicu espublizáu n'abril de 2000 (ast) scientific article published on 01 April 2000 (en)
publication date	wds:Q73665654-B4CC2B50-AF5C-40B7-AECA-EC2E2391A102
publication date	2000-04-01 00:00:00Z (xsd:dateTime)
cites work	wds:Q73665654-1E11F488-E2B9-4823-971A-0ECCFC0A525D wds:Q73665654-23AA6F63-A225-4A86-991C-5C403879B75F wds:Q73665654-26340223-FB4B-4249-888C-F9FFBBFCF60F wds:Q73665654-30BA7260-8C6B-496A-9686-5A0502158E96 wds:Q73665654-396CB72B-91B3-40B8-A649-72F51C984B46 wds:Q73665654-3AAB236C-064F-420F-974D-F10C2FFC293B wds:Q73665654-3FD2DEDD-C571-47DD-9BA7-11814BAF2662 wds:Q73665654-465F33AC-374C-4192-BB92-3ED434EDA3C8 wds:Q73665654-4A4DF9C4-0E81-49C3-98BF-21A6844CC12E wds:Q73665654-4AC531E4-228C-40C1-ADEA-14B2113ACE98 wds:Q73665654-4D4F8946-8217-4E6D-BA17-C063C837A871 wds:Q73665654-54A4ED2B-CACA-4338-BADF-B501DBE7300A wds:Q73665654-55CBC01A-474F-4ACD-B742-572C155625CF wds:Q73665654-60DB91E5-BFA9-422F-B288-EB59DCA4B121 wds:Q73665654-63643D70-C404-48D2-A432-F060A012CBEF wds:Q73665654-6AB9BBFE-B055-4D17-A853-EB4536519AEE wds:Q73665654-6B2AE8C8-2A7E-4140-9C08-AFCDBA23968E wds:Q73665654-7543BF71-96DC-4F7B-A685-576AF252079B wds:Q73665654-877D30A4-81BE-4D8E-AAAF-E7C64ED8EBC7 wds:Q73665654-8944C546-310C-4663-8A74-F8F314BB8A35 wds:Q73665654-8DA0F511-C256-460F-839C-9090C52DE72F wds:Q73665654-983B0F36-80BA-4F3F-8CEE-5AEE4B814E39 wds:Q73665654-B75B1D6B-9555-4C8D-BDD4-DA38A78627C4 wds:Q73665654-BCAE55C7-497E-4291-8D6B-153798A0971C wds:Q73665654-CA80054B-BAF7-419A-B876-3B7E03B1920F wds:Q73665654-D53B1533-8CCC-4897-907F-9064C140C1C9 wds:Q73665654-D938B7B1-E329-4139-8C06-510562C00CDA wds:Q73665654-E5370105-AC44-482A-96DE-4CB4E80F6413 wds:Q73665654-EA2585B5-DB8B-467C-B798-89346D731F5B wds:Q73665654-F2D5DCF0-9CFE-45EE-9349-2393714A4100 wds:Q73665654-FD06D67B-5EF2-4C20-A33D-A09B946EED56 wds:Q73665654-FE5C64B6-5975-450C-A612-20AA89438A43 wds:Q73665654-FF4FA3C9-2899-4A71-89FC-D7FB375B30B0
cites work	Clozapine increases dopamine release in prefrontal cortex by 5-HT1A receptor activation Clinical studies on the mechanism of action of clozapine: the dopamine-serotonin hypothesis of schizophrenia LIGAND: A versatile computerized approach for characterization of ligand-binding systems Antipsychotic drug doses and neuroleptic/dopamine receptors The dopamine D3-receptor: a postsynaptic receptor inhibitory on rat locomotor activity Learning and memory in monozygotic twins discordant for schizophrenia. Characterization of the human dopamine D3 receptor expressed in transfected cell lines Characterization of binding of [3H]PD 128907, a selective dopamine D3 receptor agonist ligand, to CHO-K1 cells THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONS Intracellular and extracellular electrophysiology of nigral dopaminergic neurons--1. Identification and characterization. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Clozapine is a partial agonist at cloned, human serotonin 5-HT1A receptors. Antipsychotic-like profile of combined treatment with raclopride and 8-OH-DPAT in the rat: enhancement of antipsychotic-like effects without catalepsy Antipsychotic properties of the partial dopamine agonist (-)-3-(3-hydroxyphenyl)-N-n-propylpiperidine(preclamol) in schizophrenia PD 158771, a potential antipsychotic agent with D2/D3 partial agonist and 5-HT(1A) agonist actions. II. Preclinical behavioral effects. Aminopyrimidines with high affinity for both serotonin and dopamine receptors 5-HT1A receptor agonists: recent developments and controversial issues Dopamine receptor pharmacology Dopaminergic neurons: An in vivo system for measuring drug interactions with presynaptic receptors Localization of dopamine D3 receptor mRNA in the rat brain using in situ hybridization histochemistry: comparison with dopamine D2 receptor mRNA. The 5-HT 1A receptor agonist, 8-OH-DPAT, preferentially activates cell body 5-HT autoreceptors in rat brain in vivo Survey on the pharmacodynamics of the new antipsychotic risperidone Dopamine agonist treatment of schizophrenia with N-propylnorapomorphine. Characterization of the binding of 3H-SCH 23390, a selective D-1 receptor antagonist ligand, in rat striatum. Effect of metergoline, fenfluramine, and 8-OHDPAT on catalepsy induced by haloperidol or morphine Evidence that striatal synthesis-inhibiting autoreceptors are dopamine D3 receptors Selective labeling of 5-HT1A and 5-HT1B binding sites in bovine brain. Dopamine receptor agonists: intrinsic activity vs. state of receptor Differential inhibition of serotonin release by 5-HT and NA reuptake blockers after systemic administration Evidence for specific interactions between 5-HT1A and dopamine D2 receptor mechanisms in the mediation of extrapyramidal motor functions in the rat Antihistamine activity, central nervous system and cardiovascular profiles of histamine H1 antagonists: comparative studies with loratadine, terfenadine and sedating antihistamines in guinea-pigs. Lack of involvement of haloperidol-sensitive sigma binding sites in modulation of dopamine neuronal activity and induction of dystonias by antipsychotic drugs Cloning, expression and characterization of a human dopamine D4.2 receptor (CHO K1 cells) and various D4.2/D2L chimeras (COS-7 cells)
author name string	wds:Q73665654-11275C73-7737-46A7-A388-4B99A2FA77F9 wds:Q73665654-5F903B56-FF1A-433C-A3FA-2EE8413B2191 wds:Q73665654-656F83D1-E941-4967-930C-7601E6A389AD wds:Q73665654-689826AC-376B-43C8-B869-C9D22DF8D0B9 wds:Q73665654-85F3B6E4-A765-4F15-B59F-31A30808BB7C wds:Q73665654-8B0AC456-A194-45F6-AA8C-DB2AAE34A25C wds:Q73665654-B57A45F6-B607-46AE-9B80-805405B7651E wds:Q73665654-BF1A7FE8-EF5D-410D-BF4B-6171F63B804D wds:Q73665654-CD628ECB-F64F-45C4-8E25-D63371E88EDE wds:Q73665654-DE9F6C68-B4A0-4C59-9288-9DF962586728 wds:Q73665654-ED77ABDD-1C69-42AE-910D-74B77F15D48C wds:Q73665654-EFCA1208-AFB9-44E4-ACC9-17647D186D9A wds:Q73665654-FC757C5A-D655-4100-9AEB-2A20DEB092FD
author name string	M D Davis Y H Shih H C Akunne R G MacKenzie T G Heffner L T Meltzer D J Wustrow T A Pugsley L D Wise L M Georgic L W Cooke

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