About: Absence of mutations in the kinase domain of the Met gene and frequent expression of Met and HGF/SF protein in primary gastric carcinomas

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About: Absence of mutations in the kinase domain of the Met gene and frequent expression of Met and HGF/SF protein in primary gastric carcinomas Goto Sponge NotDistinct Permalink

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scientific article published on 01 March 2000

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) wüsseschaftlicher Artikel, wo im März 2000 veröffentlicht worden isch (gsw) im März 2000 veröffentlichter wissenschaftlicher Artikel (de) наукова стаття, опублікована в березні 2000 (uk) article scientifique publié en 2000 (fr) artículu científicu espublizáu en marzu de 2000 (ast) scientific article published on 01 March 2000 (en)
publication date	wds:Q73639428-C919BFD9-CF81-479B-BB58-46A15BC51441
publication date	2000-03-01 00:00:00Z (xsd:dateTime)
cites work	wds:Q73639428-09D1040C-5E85-4484-ADC1-98CBB001C4B2 wds:Q73639428-15026439-680A-45B0-818A-4EB84FD839A5 wds:Q73639428-2AF23532-C6F1-4133-8834-093690B998DE wds:Q73639428-31490D0E-9CF9-4A98-AD2C-382DF5DA8785 wds:Q73639428-73289C5E-EDB8-4F61-A4B8-CDD16D7C5653 wds:Q73639428-79369517-EC74-46B3-8178-F36CDAB7DF82 wds:Q73639428-7CC9510E-1B01-499A-8A1F-12C92F55D708 wds:Q73639428-A84CE64E-1368-4121-BFCE-782600AFC1D2 wds:Q73639428-BF492F63-9C84-4339-964C-F00ED59E338F wds:Q73639428-C9A826CD-9B31-46CF-8CA1-0C8AEFF0B19A wds:Q73639428-DA49E5B8-B9C2-4877-A8CF-DEB64D653A33 wds:Q73639428-F2FDE629-BB3F-4EE5-9660-C36F49F4AC23 wds:Q73639428-F3142398-5C90-411E-AA28-E59E4D9689DA
cites work	A simple, precise and economical microdissection technique for analysis of genomic DNA from archival tissue sections Mechanism of met oncogene activation Trisomy 7-harbouring non-random duplication of the mutant MET allele in hereditary papillary renal carcinomas Frequent amplification of the c-met gene in scirrhous type stomach cancer. The two histological main types of gastric carcinoma: diffuse and so called intestinal-type carcinoma: an attempt at a histo-clinical classification The receptor encoded by the human c-MET oncogene is expressed in hepatocytes, epithelial cells and solid tumors Sequence of MET protooncogene cDNA has features characteristic of the tyrosine kinase family of growth-factor receptors The met proto-oncogene receptor and lumen formation The Met receptor tyrosine kinase transduces motility, proliferation, and morphogenic signals of scatter factor/hepatocyte growth factor in epithelial cells Intron-exon structure of the MET gene and cloning of an alternatively-spliced Met isoform reveals frequent exon-skipping of a single large internal exon Aberrant expression of c-met mRNA in human gastric carcinomas The Met-HGF/SF autocrine signaling mechanism is involved in sarcomagenesis Hepatocyte growth factor and transforming growth factor-beta stimulate both cell growth and migration of human gastric adenocarcinoma cells
author name string	wds:Q73639428-132A8987-B940-4D16-910F-BCA0F2ADBFC6 wds:Q73639428-1B07BE95-707F-4042-9276-96BF08A26F8A wds:Q73639428-1DC3549A-60CE-4FD5-8874-BF467B161D25 wds:Q73639428-2074AD0A-A0D8-4CA2-B7E9-A53B4739405F wds:Q73639428-6E5506AA-4B9F-46B2-823B-6B35BEACB9D7 wds:Q73639428-8605DB69-7C27-4F1A-BD4E-535325CB4418 wds:Q73639428-AC3C6A72-AB21-4086-A071-B10218B17F29 wds:Q73639428-D0FA004F-6047-4DAD-8BD2-0D40D5DD399B wds:Q73639428-D4F42955-215E-4702-AF5C-2ACEB82055F9
author name string	J Y Lee Y S Kim H K Lee S H Lee N J Yoo W S Park M S Shin J Y Park R R Oh
rdfs:label	Absence of mutations in the kinase domain of the Met gene and frequent expression of Met and HGF/SF protein in primary gastric carcinomas (en) Absence of mutations in the kinase domain of the Met gene and frequent expression of Met and HGF/SF protein in primary gastric carcinomas (nl)
skos:prefLabel	Absence of mutations in the kinase domain of the Met gene and frequent expression of Met and HGF/SF protein in primary gastric carcinomas (en) Absence of mutations in the kinase domain of the Met gene and frequent expression of Met and HGF/SF protein in primary gastric carcinomas (nl)
name	Absence of mutations in the kinase domain of the Met gene and frequent expression of Met and HGF/SF protein in primary gastric carcinomas (en) Absence of mutations in the kinase domain of the Met gene and frequent expression of Met and HGF/SF protein in primary gastric carcinomas (nl)
title	wds:Q73639428-2BEC8341-7C20-4C88-A097-C39DE90EEB71
title	Absence of mutations in the kinase domain of the Met gene and frequent expression of Met and HGF/SF protein in primary gastric carcinomas (en)
page(s)	wds:Q73639428-3C662BF2-A570-4018-A817-7F8FAA0349E0
page(s)	195-200
instance of	wds:Q73639428-D511CD70-A618-4C9A-9476-D284048233DE
instance of	scholarly article
PubMed ID	wds:Q73639428-3D1777A9-5E8E-4752-A120-A728AEA45922
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/10752688
PubMed ID	10752688
published in	wds:Q73639428-EF1BED1D-10BA-489E-9141-4358664A90CA
published in	Acta Pathologica et Microbiologica Scandinavica
issue	wds:Q73639428-B009400F-975C-42C6-B748-19EEDC35F43F
volume	wds:Q73639428-82D0BEF1-01C5-4D7B-8588-AA0F09497114
issue	3
volume	108
DOI	wds:Q73639428-DE63CF49-464B-47EC-AB94-80879F0FF99C
DOI	http://dx.doi.org/10.1034/J.1600-0463.2000.D01-44.X
DOI	10.1034/J.1600-0463.2000.D01-44.X
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q73639428
is cites work of	Overexpression of S100A4 is closely associated with progression of colorectal cancer Role of the hepatocyte growth factor receptor, c-Met, in oncogenesis and potential for therapeutic inhibition MET amplification as a potential therapeutic target in gastric cancer. MET overexpression assessed by new interpretation method predicts gene amplification and poor survival in advanced gastric carcinomas Inactivating mutations of the Siah-1 gene in gastric cancer Pin1 overexpression in colorectal cancer and its correlation with aberrant beta-catenin expression Expression of HGF/SF and Met protein is associated with genetic alterations of VHL gene in primary renal cell carcinomas. Genetic alterations and expression pattern of CEACAM1 in colorectal adenomas and cancers Tyrosine kinases and gastric cancer HGF/MET-directed therapeutics in gastroesophageal cancer: a review of clinical and biomarker development Molecular and biologic basis of upper gastrointestinal malignancy. Gastric carcinoma Overexpression of S100A4 is closely related to the aggressiveness of gastric cancer. S100A4 overexpression proves to be independent marker for breast cancer progression SNPs in the coding region of the metastasis-inducing gene MACC1 and clinical outcome in colorectal cancer Targeting MET Amplification as a New Oncogenic Driver. Targeting c-MET in gastrointestinal tumours: rationale, opportunities and challenges MET-targeted therapy for gastric cancer: the importance of a biomarker-based strategy. Targeted therapies in gastric cancer and future perspectives. Paracrine activation of MET promotes peritoneal carcinomatosis in scirrhous gastric cancer. Direct targeting of HGF by miR-16 regulates proliferation and migration in gastric cancer. Aberrant expression of krUppel-like factor 6 protein in colorectal cancers

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