About: Isolation and characterization of 8-demethoxy steffimycins and generation of 2,8-demethoxy steffimycins in Streptomyces steffisburgensis by the nogalamycin biosynthesis genes

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About: Isolation and characterization of 8-demethoxy steffimycins and generation of 2,8-demethoxy steffimycins in Streptomyces steffisburgensis by the nogalamycin biosynthesis genes Goto Sponge NotDistinct Permalink

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scientific article published on 01 June 1997

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в червні 1997 (uk) article scientifique publié en 1997 (fr) im Juni 1997 veröffentlichter wissenschaftlicher Artikel (de) artículu científicu espublizáu en xunu de 1997 (ast) scientific article published on 01 June 1997 (en)
publication date	wds:Q73617236-8E714B02-3587-4283-83FC-22CF9B536604
publication date	1997-01-01 00:00:00Z (xsd:dateTime)
cites work	wds:Q73617236-081F9901-D316-44AA-A537-529C43DDF36B wds:Q73617236-1B5970D0-BC70-4CEE-9049-6C1D79A39FA0 wds:Q73617236-4050321B-F54E-454D-B643-8B2A6B36C463 wds:Q73617236-5D835450-298D-41FA-83BC-E7C302B66D17 wds:Q73617236-5E4B365C-2516-49A8-A494-630F043913CB wds:Q73617236-61EBF575-AB86-44FC-957A-7E67E01531AF wds:Q73617236-807B0EAF-0388-4661-A3F7-D5E61079CD30 wds:Q73617236-9BF767A3-F4AA-43DE-8E76-F8E66C71DC75 wds:Q73617236-9CED393F-E97F-4FB5-80E7-148E0149EA10 wds:Q73617236-B238AB1C-DA4D-42A0-A8F3-C837C96FAB6A wds:Q73617236-B8BCDA68-0844-4882-B351-F49531103F48 wds:Q73617236-D2898EE1-8435-48B3-AB8E-9D8000E276D9 wds:Q73617236-D336E0A4-36AE-434E-81A7-15B7D87A6E9C wds:Q73617236-FE7DE31A-9C7A-4E4C-8EB6-B651F7C041D7
cites work	Cloning and analysis of the promoter region of the erythromycin resistance gene (ermE) of Streptomyces erythraeus. Characterization of the Streptomyces peucetius ATCC 29050 genes encoding doxorubicin polyketide synthase Engineered biosynthesis of novel polyketides: influence of a downstream enzyme on the catalytic specificity of a minimal aromatic polyketide synthase Construction and characterisation of a series of multi-copy promoter-probe plasmid vectors for Streptomyces using the aminoglycoside phosphotransferase gene from Tn5 as indicator. Polyketide synthase gene manipulation: a structure-function approach in engineering novel antibiotics Production of ‘hybrid’ antibiotics by genetic engineering Streptomyces steffisburgensis sp.n Functional characterization and transcriptional analysis of a gene cluster governing early and late steps in daunorubicin biosynthesis in Streptomyces peucetius Analysis of clustered genes encoding both early and late steps in daunomycin biosynthesis by Streptomyces sp. strain C5. Production of hybrid anthracycline antibiotics by heterologous expression of Streptomyces nogalater nogalamycin biosynthesis genes. Structures of steffimycin and steffimycin B1 Steffimycin C, a new member of the steffimycin anthracyclines. Isolation and structural characterization. A new antibacterial agent (U-20,661) isolated from a Streptomycete strain. A gene cluster involved in nogalamycin biosynthesis fromStreptomyces nogalater: sequence analysis and complementation of early-block mutations in the anthracycline pathway
access restriction status	wds:Q73617236-39872C21-5037-4E66-89E1-44D8876C2309
access restriction status	open access
author name string	wds:Q73617236-0B6CC53A-485A-4767-BE63-72B92A3260AD wds:Q73617236-0ED3FC9C-4B0B-4BB6-9CD7-E6F919CE4712 wds:Q73617236-91612204-4A18-4159-8669-E811E5514281 wds:Q73617236-9758FFC2-4CF1-4800-A842-ABA562121407 wds:Q73617236-B656E9DD-66B3-4A74-B4C3-7A6A6FC6CA3B wds:Q73617236-D215F7F1-5B99-4184-9DFD-D544A7CAF924
author name string	A Hautala J Hakala K Ylihonko P Mäntsälä T Kunnari J Tuikkanen
rdfs:label	Isolation and characterization of 8-demethoxy steffimycins and generation of 2,8-demethoxy steffimycins in Streptomyces steffisburgensis by the nogalamycin biosynthesis genes (en) Isolation and characterization of 8-demethoxy steffimycins and generation of 2,8-demethoxy steffimycins in Streptomyces steffisburgensis by the nogalamycin biosynthesis genes (nl)
skos:prefLabel	Isolation and characterization of 8-demethoxy steffimycins and generation of 2,8-demethoxy steffimycins in Streptomyces steffisburgensis by the nogalamycin biosynthesis genes (en) Isolation and characterization of 8-demethoxy steffimycins and generation of 2,8-demethoxy steffimycins in Streptomyces steffisburgensis by the nogalamycin biosynthesis genes (nl)
name	Isolation and characterization of 8-demethoxy steffimycins and generation of 2,8-demethoxy steffimycins in Streptomyces steffisburgensis by the nogalamycin biosynthesis genes (en) Isolation and characterization of 8-demethoxy steffimycins and generation of 2,8-demethoxy steffimycins in Streptomyces steffisburgensis by the nogalamycin biosynthesis genes (nl)
title	wds:Q73617236-4401330F-8883-40D0-AC56-9FE7E9F1B297
title	Isolation and characterization of 8-demethoxy steffimycins and generation of 2,8-demethoxy steffimycins in Streptomyces steffisburgensis by the nogalamycin biosynthesis genes (en)
page(s)	wds:Q73617236-9EBE3B4D-2F3E-4069-A16A-E792B4713228
page(s)	496-501
instance of	wds:Q73617236-C502C190-A4EC-4DD3-AD90-0E73CC6769FA
instance of	scholarly article
main subject	wds:Q73617236-326C560F-7A80-44FF-917F-C54674CACFD6 wds:Q73617236-4749FB0C-2F5D-4214-A3D1-4AA9B60E476E wds:Q73617236-5D814C79-F502-403D-A22F-FCD0EB286566 wds:Q73617236-755067DE-8F58-4B63-BB33-69DDAA9316F7 wds:Q73617236-844ABDC5-37E8-4461-87E6-93B894BE1E32 wds:Q73617236-A45AB3B4-3FE6-4EF3-AB99-4C0E7D84333E wds:Q73617236-B950B0BA-0ADF-4CA1-B091-2D10A730E596 wds:Q73617236-CE4F7862-F5C1-4C9D-ADDC-828DA1EFDE29 wds:Q73617236-D49B1E4C-3D56-45E1-A82F-A69A710E4519 wds:Q73617236-E71E42F6-A0D1-44F8-8433-1AEADECDD011 wds:Q73617236-F81B12DE-4F8C-498A-96F4-FBF6EC36E29D
main subject	Streptomyces steffisburgensis 8-Demethoxy-steffimycin D (7S,9R)-6,9-dihydroxy-2-methoxy-9-methyl-7-[(2R,3S,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy-8,10-dihydro-7H-tetracene-5,12-dione (7S,9R)-6,9-dihydroxy-9-methyl-7-[(2R,3S,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy-8,10-dihydro-7H-tetracene-5,12-dione (2S,3R,4S)-4-[(2S,3S,4R,5R,6S)-4,5-dihydroxy-3-methoxy-6-methyloxan-2-yl]oxy-2,5-dihydroxy-3,9-dimethoxy-2-methyl-3,4-dihydrotetracene-1,6,11-trione (7R,9R)-7-[(2R,3S,4R,5R,6S)-4,5-dihydroxy-3-methoxy-6-methyloxan-2-yl]oxy-6,9-dihydroxy-2-methoxy-9-methyl-8,10-dihydro-7H-tetracene-5,12-dione (2S,4R)-4-[(2R,3S,4R,5R,6S)-4,5-dihydroxy-3-methoxy-6-methyloxan-2-yl]oxy-2,5-dihydroxy-9-methoxy-2-methyl-3,4-dihydrotetracene-1,6,11-trione Steffimycin E 8,2'-Demethoxy-steffimycin C 8-Demethoxy-steffimycin A Steffimycin E
PubMed ID	wds:Q73617236-002E29E5-FEA7-44C1-9AD5-1B8A711B9835
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/9268006
PubMed ID	9268006
published in	wds:Q73617236-92360BF3-61C8-42CE-8EF2-C42190C2A9F9
full work available at URL	wds:Q73617236-E3D3DC0A-CB51-4817-8FA5-64E44DD30EFB
published in	The Journal of Antibiotics
full work available at URL	https://www.jstage.jst.go.jp/article/antibiotics1968/50/6/50_6_496/_pdf
issue	wds:Q73617236-89403F4A-0A6D-4FD5-98DB-5F68ACC8AA02
volume	wds:Q73617236-A42A694F-AFE9-4766-8111-5FD061B66D7B
issue	6
volume	50
DOI	wds:Q73617236-8089E830-DF1B-46D9-A312-C3B813F9F15C
DOI	http://dx.doi.org/10.7164/ANTIBIOTICS.50.496
DOI	10.7164/ANTIBIOTICS.50.496
online access status	wds:Q73617236-D6524995-B1DC-4E81-8D44-D64A8D7AEA98

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