About: Apolipoprotein E is resistant to intracellular degradation in vitro and in vivo. Evidence for retroendocytosis

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About: Apolipoprotein E is resistant to intracellular degradation in vitro and in vivo. Evidence for retroendocytosis Goto Sponge NotDistinct Permalink

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scientific article published on 01 March 2000

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rdf:type	Item
description	wetenschappelijk artikel (nl) wüsseschaftlicher Artikel, wo im März 2000 veröffentlicht worden isch (gsw) im März 2000 veröffentlichter wissenschaftlicher Artikel (de) наукова стаття, опублікована в березні 2000 (uk) artículu científicu espublizáu en marzu de 2000 (ast) scientific article published on 01 March 2000 (en)
publication date	wds:Q73561089-68104735-4F1E-4069-BA57-FAF83A95AE88
publication date	2000-03-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q73561089-941F4118-78FE-4BEF-A7C7-8186C8E29FE1
language of work or name	English
cites work	wds:Q73561089-02BFFE8B-B3F0-4D3F-9E02-07F9E6BDF6F9 wds:Q73561089-03BE1C89-1627-46CC-A9FD-A1968D0DE296 wds:Q73561089-0434E3DA-A8B5-4C79-92B0-F212E99184B9 wds:Q73561089-09837CFE-F0A2-48E1-A1EE-27A461E43ABF wds:Q73561089-1D80B5AB-CC28-4F8A-9318-132ACB449BAE wds:Q73561089-21BA595E-A719-4F2A-AA6D-084EA8F2FE12 wds:Q73561089-21DBD76C-33C9-458E-85F5-7484340B3789 wds:Q73561089-23BA5ADE-E09B-45AC-9A44-03B57620EC0C wds:Q73561089-2AB55261-F56C-40CE-B0FE-984082DB58FD wds:Q73561089-32D596D8-04C3-4ECC-9992-44084F807FB9 wds:Q73561089-412804F8-15D5-4743-B2CF-DA4E9B42D8E9 wds:Q73561089-43848DFE-2247-4978-BDB1-163A732835CA wds:Q73561089-445A3825-C7E4-4779-BE1E-874AAFF6F111 wds:Q73561089-4ABAC3E3-3FDA-4AC7-983C-EA6BEA9EABEF wds:Q73561089-54222FF4-56D6-472E-949B-7EDF7A295167 wds:Q73561089-5A7E9388-395F-43B0-B4C9-F52392E3598A wds:Q73561089-622B1D3E-102B-4A35-B5B5-CE6DBC65B14A wds:Q73561089-6B862852-7A76-492C-83DA-D2CA59AD96B1 wds:Q73561089-6D40CDB7-0E77-4247-B8D4-DEFFAA613DBF wds:Q73561089-6E00D047-5183-41AB-972C-0DA8D099E625 wds:Q73561089-6FD9CA4A-D415-48FE-82BB-824DB1B2EA05 wds:Q73561089-89687157-9D53-4785-B30E-1F63C382CE87 wds:Q73561089-8C535C4E-0CD6-45B2-A418-12D7F52A145B wds:Q73561089-9CA0CC59-29D4-49D8-8A89-56E76303608A wds:Q73561089-BDBB5113-29EC-4189-B212-57881AD68401 wds:Q73561089-C9A8CEBD-206D-45A9-8D7D-D84D1F57F850 wds:Q73561089-D5DFDC87-6E77-401D-8D39-3D0CE1DAA1FC wds:Q73561089-D86B2A43-B490-4E2F-841D-4F2E298D2634 wds:Q73561089-DD0CAA3D-F345-4602-BD40-E85A4109341F wds:Q73561089-DF3D769C-A0BD-41BB-937D-D5D67033031C wds:Q73561089-E80E7F53-2993-4E9C-B8EC-C64EC4AC748E wds:Q73561089-ECCC8166-61A4-4727-81B9-7670BDB530B8 wds:Q73561089-EE504473-1951-4296-A339-3340B4A602B2
cites work	Receptor-mediated endocytosis: insights from the lipoprotein receptor system Rate and equilibrium constants for binding of apo-E HDL c (a cholesterol-induced lipoprotein) and low density lipoproteins to human fibroblasts: Evidence for multiple receptor binding of apo-E HDL c Inhibition of hepatic chylomicron remnant uptake by gene transfer of a receptor antagonist Efficient Trace-labelling of Proteins with Iodine pH and the recycling of transferrin during receptor-mediated endocytosis Impaired secretion of very low density lipoprotein-triglycerides by apolipoprotein E- deficient mouse hepatocytes A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION 19 Receptor-mediated endocytosis of low-density lipoprotein in cultured cells Apolipoprotein E: cholesterol transport protein with expanding role in cell biology The LDL-receptor-related protein, LRP, is an apolipoprotein E-binding protein Overexpression and accumulation of apolipoprotein E as a cause of hypertriglyceridemia Endocytosed beta-VLDL and LDL are delivered to different intracellular vesicles in mouse peritoneal macrophages Apolipoprotein E effectively inhibits lipoprotein lipase-mediated lipolysis of chylomicron-like triglyceride-rich lipid emulsions in vitro and in vivo. Beta-very low density lipoprotein is sequestered in surface-connected tubules in mouse peritoneal macrophages Separation of plasma lipoproteins by density-gradient ultracentrifugation Cholesterol derivative of a new triantennary cluster galactoside directs low- and high-density lipoproteins to the parenchymal liver cell Human recombinant apolipoprotein E-enriched liposomes can mimic low-density lipoproteins as carriers for the site-specific delivery of antitumor agents Recycling of apolipoprotein E in mouse liver Lactoferrin binding to heparan sulfate proteoglycans and the LDL receptor-related protein. Further evidence supporting the importance of direct binding of remnant lipoproteins to HSPG Intracellular localization and metabolism of chylomicron remnants in the livers of low density lipoprotein receptor-deficient mice and apoE-deficient mice. Evidence for slow metabolism via an alternative apoE-dependent pathway Role of the low density lipoprotein (LDL) receptor pathway in the metabolism of chylomicron remnants. A quantitative study in knockout mice lacking the LDL receptor, apolipoprotein E, or both Selective liver targeting of antivirals by recombinant chylomicrons--a new therapeutic approach to hepatitis B Metabolism of protein-free lipid emulsion models of chylomicrons in rats Heparan sulfate proteoglycan-mediated uptake of apolipoprotein E-triglyceride-rich lipoprotein particles: a major pathway at physiological particle concentrations Secretion-recapture process of apolipoprotein E in hepatic uptake of chylomicron remnants in transgenic mice Differential cellular accumulation/retention of apolipoprotein E mediated by cell surface heparan sulfate proteoglycans. Apolipoproteins E3 and E2 greater than e4. The influence of particle size and multiple apoprotein E-receptor interactions on the endocytic targeting of beta-VLDL in mouse peritoneal macrophages Effects of apoprotein E on intracellular metabolism of model triglyceride-rich particles are distinct from effects on cell particle uptake Human apolipoprotein E expression in Escherichia coli: structural and functional identity of the bacterially produced protein with plasma apolipoprotein E. Low-density lipoproteins are degraded in HepG2 cells with low efficiency Enhanced metabolism of normolipidemic human plasma very low density lipoprotein in cultured cells by exogenous apolipoprotein E-3 Binding of beta-VLDL to heparan sulfate proteoglycans requires lipoprotein lipase, whereas ApoE only modulates binding affinity Plasma factors affecting the in vitro conversion of high-density lipoproteins labeled with a non-transferable marker
author name string	wds:Q73561089-56763318-8343-47CC-99BF-F7165AD81AFB wds:Q73561089-90569631-9AC9-48E8-A139-443D46BB4E5B wds:Q73561089-9F681831-928C-4C2E-9A73-BB513073E3BB wds:Q73561089-AF70D4AA-13F5-40A8-A24A-FAE567BE2996 wds:Q73561089-B0417F5C-F9F8-47AB-A043-0BD35F92DACA wds:Q73561089-CD0840EF-B192-4A2B-8250-9CB919E1AB82 wds:Q73561089-F49CFF9C-4906-4CD9-9069-4C84C639274B
author name string	L M Havekes T J van Berkel H van der Boom M C Jong E A Biessen L C van Vark W L Hendriks
rdfs:label	Apolipoprotein E is resistant to intracellular degradation in vitro and in vivo. Evidence for retroendocytosis (en) Apolipoprotein E is resistant to intracellular degradation in vitro and in vivo. Evidence for retroendocytosis (nl)
skos:prefLabel	Apolipoprotein E is resistant to intracellular degradation in vitro and in vivo. Evidence for retroendocytosis (en) Apolipoprotein E is resistant to intracellular degradation in vitro and in vivo. Evidence for retroendocytosis (nl)
name	Apolipoprotein E is resistant to intracellular degradation in vitro and in vivo. Evidence for retroendocytosis (en) Apolipoprotein E is resistant to intracellular degradation in vitro and in vivo. Evidence for retroendocytosis (nl)
author	wds:Q73561089-CC51FABA-30EB-4BE3-A7E8-D60D9AB543F0
author	Patrick Rensen
title	wds:Q73561089-4B71736E-1129-4A02-B4B7-DC5D1F735BAA

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