About: Selective loss of fibrinogen clotting in a loop-less thrombin

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scientific article published on 01 August 1997

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в серпні 1997 (uk) im August 1997 veröffentlichter wissenschaftlicher Artikel (de) artículu científicu espublizáu n'agostu de 1997 (ast) scientific article published on 01 August 1997 (en)
publication date	wds:Q73555471-5D59D37D-56C5-446B-ADBB-053DDEC7C3C7
publication date	1997-08-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q73555471-3AAD603F-FAC8-42D4-BF3F-58AC7936640B
language of work or name	English
cites work	wds:Q73555471-0A781FBD-FABD-4840-A4FD-994E36B64DF0 wds:Q73555471-2B73CF6D-F13F-4DC1-9300-42494AB7FF67 wds:Q73555471-34E0603E-E4FA-46ED-9C0B-F72C9387E5A4 wds:Q73555471-395BAB16-F27F-4CB9-A8BF-C671DF64E45B wds:Q73555471-3D68B7CB-D4CF-404E-B99D-9F6FA2BA18AD wds:Q73555471-4E2C71E2-89ED-46B4-A59B-C61C9D094BEA wds:Q73555471-6933D019-2E21-4CA2-887F-6E74543F55CF wds:Q73555471-7D53E12D-E7EC-4FF2-AD63-51544041BF34 wds:Q73555471-98FFFF36-2700-4937-940D-FD07E7309DCD wds:Q73555471-A0A7CAF5-8B51-4561-9F8D-65819F9A8B2A wds:Q73555471-A69F34BD-7526-4C24-8835-0823BD1F58E2 wds:Q73555471-CF716E60-BD2F-4419-976F-36EA850AE7BA wds:Q73555471-D2031B13-7387-40D6-80B6-18E354BB85A8 wds:Q73555471-D82F76AF-0D58-4705-9528-0E2A94C931E5 wds:Q73555471-D95578A8-2E38-4D79-8151-2A3A3B6CEAB1 wds:Q73555471-FE67FC3C-AB5E-48A2-9423-F393A573C70C
cites work	The refined 1.9-Å X-ray crystal structure of d-Phe-Pro-Arg chloromethylketone-inhibited human α-thrombin: Structure analysis, overall structure, electrostatic properties, detailed active-site geometry, and structure-function relationships The coagulation cascade: initiation, maintenance, and regulation Partial characterization of vertebrate prothrombin cDNAs: amplification and sequence analysis of the B chain of thrombin from nine different species Refined structure of the hirudin-thrombin complex The interaction of thrombin with fibrinogen. A structural basis for its specificity Identification of residues linked to the slow-->fast transition of thrombin An allosteric switch controls the procoagulant and anticoagulant activities of thrombin Thrombin is a Na(+)-activated enzyme Conversion of thrombin into an anticoagulant by protein engineering Rational engineering of activity and specificity in a serine protease Protein engineering thrombin for optimal specificity and potency of anticoagulant activity in vivo Energetics of thrombin-thrombomodulin interaction. The role of the insertion loop around tryptophan 148 in tthe activity of thrombin Structure of a nonadecapeptide of the fifth EGF domain of thrombomodulin complexed with thrombin Prothrombin Salakta: substitution of glutamic acid-466 by alanine reduces the fibrinogen clotting activity and the esterase activity Enhanced protein C activation and inhibition of fibrinogen cleavage by a thrombin modulator
author name string	wds:Q73555471-1DD104C3-7455-406A-BC2B-8C31DBE3E7D0 wds:Q73555471-318F53A2-0EC1-4229-A360-BBB5455DD073 wds:Q73555471-7FED7653-9958-4922-A60E-FEBAC5754CDC
author name string	E Di Cera Q D Dang M Sabetta
rdfs:label	Selective loss of fibrinogen clotting in a loop-less thrombin (en) Selective loss of fibrinogen clotting in a loop-less thrombin (nl)
skos:prefLabel	Selective loss of fibrinogen clotting in a loop-less thrombin (en) Selective loss of fibrinogen clotting in a loop-less thrombin (nl)
name	Selective loss of fibrinogen clotting in a loop-less thrombin (en) Selective loss of fibrinogen clotting in a loop-less thrombin (nl)
title	wds:Q73555471-F86C2D71-B8AB-44AD-8D94-10B2BD6FB9C0
title	Selective loss of fibrinogen clotting in a loop-less thrombin (en)
page(s)	wds:Q73555471-9BFADE89-DAF0-49A0-BFF5-DF017BB3E285
page(s)	19649-19651
instance of	wds:Q73555471-410EF42E-7197-45C9-880D-BDB91F5A7385
instance of	scholarly article
PubMed ID	wds:Q73555471-0A38CD28-300A-4830-B3BE-1EEA64DF25A8
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/9242618
PubMed ID	9242618
published in	wds:Q73555471-D8EC74E6-1AE3-43E4-A7D5-95F9A2739A04
published in	Journal of Biological Chemistry
issue	wds:Q73555471-EDF7287F-E908-4EB6-9677-C156B2E16FBD
volume	wds:Q73555471-A3954064-FA3B-4E3F-8446-871E93A04576
issue	32
volume	272
DOI	wds:Q73555471-FEBC9F96-0859-44FB-A969-A5DAEDDC9FBE
DOI	http://dx.doi.org/10.1074/JBC.272.32.19649
DOI	10.1074/JBC.272.32.19649
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q73555471
is cites work of	Ligand binding to anion-binding exosites regulates conformational properties of thrombin Allostery in trypsin-like proteases suggests new therapeutic strategies Mutant N143P Reveals How Na+ Activates Thrombin Rigidification of the autolysis loop enhances Na+ binding to thrombin Effect of Na+ binding on the conformation, stability and molecular recognition properties of thrombin Examining thrombin hydrolysis of the factor XIII activation peptide segment leads to a proposal for explaining the cardioprotective effects observed with the factor XIII V34L mutation Anticoagulant thrombins. Molecular mapping of thrombin-receptor interactions Stabilization of the E* Form Turns Thrombin into an Anticoagulant Thrombin Mechanism of the Anticoagulant Activity of Thrombin Mutant W215A/E217A Activation of factor XI by products of prothrombin activation Protease-activated receptor 4-like peptides bind to thrombin through an optimized interaction with the enzyme active site surface Salmon-derived thrombin inhibits development of chronic pain through an endothelial barrier protective mechanism dependent on APC. Role of P225 and the C136-C201 disulfide bond in tissue plasminogen activator Redesigning allosteric activation in an enzyme Site-specific analysis of mutational effects in proteins. Engineering thrombin for selective specificity toward protein C and PAR1. Probing thrombin's ability to accommodate a V34F substitution within the factor XIII activation peptide segment (28-41). Proline 36 of the Factor XIII Activation Peptide Plays a Crucial Role in Substrate Recognition and Zymogen Activation Design of Factor XIII V34X activation peptides to control ability to interact with thrombin mutants Mutations in autolytic loop-2 and at Asp554 of human prothrombin that enhance protein C activation by meizothrombin
is cites work of	wds:Q27655637-B8C7C3B9-D1E0-47DB-9496-19B0666F58D8 wds:Q34750145-A9FA0EBD-14C0-40EA-8AA1-1BD4D782BC7D wds:Q35317139-2EFE77CB-8418-4476-BB85-D262EDF10B70 wds:Q36708674-CB7E0F85-2857-4C05-9281-8D03967A11B9 wds:Q51708222-92F7B870-03D6-4AF7-AFE4-57CD6AAEC2CF

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