About: 5-Iodo-A-85380, an alpha4beta2 subtype-selective ligand for nicotinic acetylcholine receptors

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About: 5-Iodo-A-85380, an alpha4beta2 subtype-selective ligand for nicotinic acetylcholine receptors Goto Sponge NotDistinct Permalink

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scientific article published on 01 March 2000

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) wüsseschaftlicher Artikel, wo im März 2000 veröffentlicht worden isch (gsw) im März 2000 veröffentlichter wissenschaftlicher Artikel (de) наукова стаття, опублікована в березні 2000 (uk) artículu científicu espublizáu en marzu de 2000 (ast) scientific article published on 01 March 2000 (en)
publication date	wds:Q73487540-1C907A21-DD7E-45CA-AA72-08CA40A3F0FA
publication date	2000-03-01 00:00:00Z (xsd:dateTime)
author name string	wds:Q73487540-0E0BF0F2-DA84-4BF0-848C-9B26421C65E8 wds:Q73487540-2055F474-9583-4DED-9393-3FB42B2350DF wds:Q73487540-20FBA439-2ECE-43D7-863A-50C5285314BF wds:Q73487540-3CAA6175-5E16-4C1C-AE10-B0ABA4A0CAE1 wds:Q73487540-4909B494-324C-4BAB-928B-BA636F7B15E0 wds:Q73487540-574B52EF-55B5-460D-84AA-88DE2F840137 wds:Q73487540-682E74AC-1D74-4F00-98A7-1A76769226D3 wds:Q73487540-751D783C-FAF0-45C3-AF7A-F811F6F38FF3 wds:Q73487540-BEE7CC1E-4BE8-4E7D-8F76-9D84AD22A10E wds:Q73487540-D3746889-BC96-47DB-BFA5-B297118D1D35
author name string	J Chambers R B Innis A G Mukhin A S Kimes D B Vaupel A G Horti A O Koren D Gündisch G Tamagnan M R Picciotto
rdfs:label	5-Iodo-A-85380, an alpha4beta2 subtype-selective ligand for nicotinic acetylcholine receptors (en) 5-Iodo-A-85380, an alpha4beta2 subtype-selective ligand for nicotinic acetylcholine receptors (nl)
skos:prefLabel	5-Iodo-A-85380, an alpha4beta2 subtype-selective ligand for nicotinic acetylcholine receptors (en) 5-Iodo-A-85380, an alpha4beta2 subtype-selective ligand for nicotinic acetylcholine receptors (nl)
name	5-Iodo-A-85380, an alpha4beta2 subtype-selective ligand for nicotinic acetylcholine receptors (en) 5-Iodo-A-85380, an alpha4beta2 subtype-selective ligand for nicotinic acetylcholine receptors (nl)
author	wds:Q73487540-E494429C-3B0B-46DA-9A84-58A3C021912D wds:Q73487540-F759BAB9-0B94-48D9-A520-D533ED251740
author	Edythe D. London Sarah L King
title	wds:Q73487540-73AF329A-6D48-4A3C-A98E-010327C4ACE5
title	5-Iodo-A-85380, an alpha4beta2 subtype-selective ligand for nicotinic acetylcholine receptors (en)
page(s)	wds:Q73487540-1440203C-E7A2-4D82-A90F-57F3753EEF3E
page(s)	642-649
instance of	wds:Q73487540-439BE23F-ECB9-4B8E-B689-99417993355B
instance of	scholarly article
PubMed ID	wds:Q73487540-775837CD-11AD-41EC-9652-3F00294BD1D1
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/10692507
PubMed ID	10692507
published in	wds:Q73487540-D667F38B-65D3-4F26-85E9-D4EEEB99F462
published in	Molecular Pharmacology
issue	wds:Q73487540-B364ED5D-1060-4406-8BE8-BD6E3615F3AA
volume	wds:Q73487540-F6F42295-67E9-4ADC-9089-53A6BCABF466
issue	3
volume	57
DOI	wds:Q73487540-6BB52ADB-7063-40CE-AE7C-BEBB2D3603BB
DOI	http://dx.doi.org/10.1124/MOL.57.3.642
DOI	10.1124/MOL.57.3.642
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q73487540
is cites work of	α6β2* and α4β2* nicotinic acetylcholine receptors as drug targets for Parkinson's disease Calcium signalling mediated through α7 and non-α7 nAChR stimulation is differentially regulated in bovine chromaffin cells to induce catecholamine release Comparison of effects produced by nicotine and the α4β2-selective agonist 5-I-A-85380 on intracranial self-stimulation in rats Development of ligands for in vivo imaging of cerebral nicotinic receptors Muscarinic and nicotinic acetylcholine receptor agonists and allosteric modulators for the treatment of schizophrenia Nicotine and hippocampus-dependent learning: implications for addiction Feasibility of [18F]-2-Fluoro-A85380-PET imaging of human vascular nicotinic acetylcholine receptors in vivo Functional brain imaging of tobacco use and dependence Single photon emission computed tomography experience with (S)-5-[(123)I]iodo-3-(2-azetidinylmethoxy)pyridine in the living human brain of smokers and nonsmokers Radiosynthesis of 5-(2-(4-pyridinyl)vinyl)-6-chloro-3-(1-[(11)C]methyl-2-(S)-pyrrolidinylmethoxy)pyridine, a high affinity ligand for studying nicotinic acetylcholine receptors by positron emission tomography Identification of a novel nicotinic binding site in mouse brain using [(125)I]-epibatidine Nicotinic cholinergic receptors in the rat cerebellum: multiple heteromeric subtypes. Measurement of plasma metabolites of (S)-5-[123I]iodo-3-(2-azetidinylmethoxy)pyridine (5-IA-85380), a nicotinic acetylcholine receptor imaging agent, in nonhuman primates Human tobacco smokers in early abstinence have higher levels of beta2* nicotinic acetylcholine receptors than nonsmokers. Presynaptic nicotinic α7 and non-α7 receptors stimulate endogenous GABA release from rat hippocampal synaptosomes through two mechanisms of action Neuronal nicotinic acetylcholine receptor subunit knockout mice: physiological and behavioral phenotypes and possible clinical implications. Positive allosteric modulation of α4β2 nicotinic acetylcholine receptors as a new approach to smoking reduction: evidence from a rat model of nicotine self-administration Pre-synaptic nicotinic receptors evoke endogenous glutamate and aspartate release from hippocampal synaptosomes by way of distinct coupling mechanisms Acetylcholine receptors in dementia and mild cognitive impairment. beta2-Nicotinic acetylcholine receptor availability during acute and prolonged abstinence from tobacco smoking Rare nonsynonymous variants in alpha-4 nicotinic acetylcholine receptor gene protect against nicotine dependence Greater nicotinic acetylcholine receptor density in smokers than in nonsmokers: a PET study with 2-18F-FA-85380. Syntheses and evaluation of halogenated cytisine derivatives and of bioisosteric thiocytisine as potent and selective nAChR ligands Differential Regulation of Nicotinic Acetylcholine Receptors in PC12 Cells by Nicotine and Nerve Growth Factor An autoradiographic survey of mouse brain nicotinic acetylcholine receptors defined by null mutants A-85380: a pharmacological probe for the preclinical and clinical investigation of the alphabeta neuronal nicotinic acetylcholine receptor. An instructive role for patterned spontaneous retinal activity in mouse visual map development Cholinergic nicotinic receptors: Competitive ligands, allosteric modulators, and their potential applications Neuronal nicotinic receptor agonists improve gait and balance in olivocerebellar ataxia Nicotine reduces established levodopa-induced dyskinesias in a monkey model of Parkinson's disease Multiple CNS nicotinic receptors mediate L-dopa-induced dyskinesias: studies with parkinsonian nicotinic receptor knockout mice [125/123I] 5-Iodo-3-pyridyl ethers. syntheses and binding to neuronal nicotinic acetylcholine receptors In vivo PET imaging of the α4β2 nicotinic acetylcholine receptor as a marker for brain inflammation after cerebral ischemia. Chemistry and pharmacology of nicotinic ligands based on 6-[5-(azetidin-2-ylmethoxy)pyridin-3-yl]hex-5-yn-1-ol (AMOP-H-OH) for possible use in depression Cytisine-based nicotinic partial agonists as novel antidepressant compounds Region-specific effects of nicotine on brain activity: a pharmacological MRI study in the drug-naïve rat. Effect of a nicotine vaccine on nicotine binding to β2-nicotinic acetylcholine receptors in vivo in human tobacco smokers Conditional expression in corticothalamic efferents reveals a developmental role for nicotinic acetylcholine receptors in modulation of passive avoidance behavior. Differential expression of the beta4 neuronal nicotinic receptor subunit affects tolerance development and nicotinic binding sites following chronic nicotine treatment Increased nicotinic acetylcholine receptor protein underlies chronic nicotine-induced up-regulation of nicotinic agonist binding sites in mouse brain Nicotinic acetylcholine receptors expressed in the ventralposterolateral thalamic nucleus play an important role in anti-allodynic effects Sex differences in availability of β2-nicotinic acetylcholine receptors in recently abstinent tobacco smokers

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