About: The rat canalicular conjugate export pump (Mrp2) is down-regulated in intrahepatic and obstructive cholestasis

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About: The rat canalicular conjugate export pump (Mrp2) is down-regulated in intrahepatic and obstructive cholestasis Goto Sponge NotDistinct Permalink

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scientific article published on 01 July 1997

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rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в липні 1997 (uk) article scientifique publié en 1997 (fr) im Juli 1997 veröffentlichter wissenschaftlicher Artikel (de) artículu científicu espublizáu en xunetu de 1997 (ast) scientific article published on 01 July 1997 (en)
publication date	wds:Q73475930-18CB8676-A17C-4B37-A3EE-4239CB61EE5D
publication date	1997-07-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q73475930-E064E528-525D-4F1A-B795-356F36CCDA5C
language of work or name	English
author name string	wds:Q73475930-022B1C5B-1BCE-4A72-BDB6-156DAC77B496 wds:Q73475930-148DDE9C-F5C3-49A4-B15C-2E608ED9A427 wds:Q73475930-1D7A1A01-87E0-42B8-A53D-6E38A1A59E87 wds:Q73475930-2C5A2361-63D4-4F49-8BC7-26135F9053F4 wds:Q73475930-79651D6B-5B58-4C99-AAAC-3A4F5C2C0622 wds:Q73475930-A666A925-3D07-477E-9CDA-06D001EDBF41 wds:Q73475930-DF169CFF-AA29-4E17-865F-A5729FC395C4 wds:Q73475930-E860DC92-6969-45CC-81A4-B4B571682141 wds:Q73475930-FA0ED516-6D98-4DCF-A901-01567D9FE5DE
author name string	D Keppler J L Boyer M Arrese M Ananthanarayanan T A Koeppel M Trauner F J Suchy S F Schlosser C J Soroka
rdfs:label	The rat canalicular conjugate export pump (nl) The rat canalicular conjugate export pump (Mrp2) is down-regulated in intrahepatic and obstructive cholestasis (en)
skos:prefLabel	The rat canalicular conjugate export pump (nl) The rat canalicular conjugate export pump (Mrp2) is down-regulated in intrahepatic and obstructive cholestasis (en)
name	The rat canalicular conjugate export pump (nl) The rat canalicular conjugate export pump (Mrp2) is down-regulated in intrahepatic and obstructive cholestasis (en)
title	wds:Q73475930-C2AAC440-29A3-46D2-8242-FDB566D4FE07
title	The rat canalicular conjugate export pump (Mrp2) is down-regulated in intrahepatic and obstructive cholestasis (en)
page(s)	wds:Q73475930-8D0148E0-81AB-4A1F-83B0-D7B72C5E0F6B
page(s)	255-264
instance of	wds:Q73475930-6B891E8C-77B7-4228-90D2-EF11D5A4602F
instance of	scholarly article
PubMed ID	wds:Q73475930-CBB4CCE1-32E0-452D-8215-9811C7BA73BD
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/9207286
PubMed ID	9207286
published in	wds:Q73475930-E36CBA60-0D40-4574-8BAB-0CBA5265996C
published in	Gastroenterology
issue	wds:Q73475930-EFB1965D-74D0-492A-9A17-CA946B2A674E
volume	wds:Q73475930-94C55DF1-4363-4C3E-BEC5-9A611D12F28F
issue	1
volume	113
DOI	wds:Q73475930-0DE2897E-2E6E-4CFD-B472-AA322731B462
DOI	http://dx.doi.org/10.1016/S0016-5085(97)70103-3
DOI	10.1016/S0016-5085(97)70103-3
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q73475930
is cites work of	Endotoxin leads to rapid subcellular re-localization of hepatic RXRalpha: A novel mechanism for reduced hepatic gene expression in inflammation Cellular regulation of hepatic bile acid transport in health and cholestasis Hepatobiliary organic anion transporters are differentially regulated in acute toxic liver injury induced by carbon tetrachloride Effects of bile salt flux variations on the expression of hepatic bile salt transporters in vivo in mice Role of farnesoid X receptor in determining hepatic ABC transporter expression and liver injury in bile duct-ligated mice Adaptive changes in hepatobiliary transporter expression in primary biliary cirrhosis. Differential expression of basolateral and canalicular organic anion transporters during regeneration of rat liver Neither intestinal sequestration of bile acids nor common bile duct ligation modulate the expression and function of the rat ileal bile acid transporter Cytokine-independent repression of rodent Ntcp in obstructive cholestasis Mrp4-/- mice have an impaired cytoprotective response in obstructive cholestasis Bile acid transporters and regulatory nuclear receptors in the liver and beyond Single nucleotide polymorphisms in multidrug resistance associated protein 2 (MRP2/ABCC2): its impact on drug disposition Up-regulation of multidrug resistance-associated protein 2 (MRP2) expression in rat hepatocytes by dexamethasone Biliary drainage for obstructive jaundice enhances hepatic energy status in humans: a 31-phosphorus magnetic resonance spectroscopy study Gender-specific reduction of hepatic Mrp2 expression by high-fat diet protects female mice from ANIT toxicity Xenobiotic, bile acid, and cholesterol transporters: function and regulation. Common variants in the SLCO1B3 locus are associated with bilirubin levels and unconjugated hyperbilirubinemia The apical conjugate efflux pump ABCC2 (MRP2). Dipeptidyl peptidase 4-deficient rats have improved bile secretory function in high fat diet-induced steatosis Molecular pathogenesis of intrahepatic cholestasis of pregnancy. Lack of hepatocellular CD10 along bile canaliculi is physiologic in early childhood and persistent in Alagille syndrome. Interindividual variability of canalicular ATP-binding-cassette (ABC)-transporter expression in human liver. Cytokines Alter the Expression and Activity of the Multidrug Resistance Transporters in Human Hepatoma Cell Lines; Analysis Using RT‐PCR and cDNA Microarrays Bile acid-induced Mallory body formation in drug-primed mouse liver Regulation of organic anion transporters in a new rat model of acute and chronic cholangitis resembling human primary sclerosing cholangitis Conjugate export pumps of the multidrug resistance protein (MRP) family: localization, substrate specificity, and MRP2-mediated drug resistance ATP-dependent transport of glutathione S-conjugates by the multidrug resistance protein MRP1 and its apical isoform MRP2. Changes in the localization of the rat canalicular conjugate export pump Mrp2 in phalloidin-induced cholestasis. The human multidrug resistance protein 2 gene: functional characterization of the 5'-flanking region and expression in hepatic cells Regulation of organic anion and drug transporters of the sinusoidal membrane Function and regulation of ATP-binding cassette transport proteins involved in hepatobiliary transport Up-regulation of the multidrug resistance genes, Mrp1 and Mdr1b, and down-regulation of the organic anion transporter, Mrp2, and the bile salt transporter, Spgp, in endotoxemic rat liver Endotoxin downregulates rat hepatic ntcp gene expression via decreased activity of critical transcription factors Hepatobiliary transport Pharmacokinetic drug interactions involving 17alpha-ethinylestradiol: a new look at an old drug Lithocholic acid feeding induces segmental bile duct obstruction and destructive cholangitis in mice. Nrf2- and PPAR alpha-mediated regulation of hepatic Mrp transporters after exposure to perfluorooctanoic acid and perfluorodecanoic acid. Regulation of basolateral organic anion transporters in ethinylestradiol-induced cholestasis in the rat. Intrahepatic cholestasis of pregnancy: molecular pathogenesis, diagnosis and management Decreased expression and activity of P-glycoprotein in rat liver during acute inflammation. Induction of hepatic multidrug resistance-associated protein 3 by ethynylestradiol is independent of cholestasis and mediated by estrogen receptor Hormonal regulation of hepatic drug biotransformation and transport systems Expression of rat Multidrug Resistance Protein 2 (Mrp2) in male and female rats during normal and pregnenolone-16alpha-carbonitrile (PCN)-induced postnatal ontogeny Elevated hepatic multidrug resistance-associated protein 3/ATP-binding cassette subfamily C 3 expression in human obstructive cholestasis is mediated through tumor necrosis factor alpha and c-Jun NH2-terminal kinase/stress-activated protein kinase-s Mechanisms of disease: mechanisms and clinical implications of cholestasis in sepsis. Expression of hepatic transporters OATP-C and MRP2 in primary sclerosing cholangitis.

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