About: Evaluation of the activity of a novel metabotropic glutamate receptor antagonist (+/-)-2-amino-2-(3-cis and trans-carboxycyclobutyl-3-(9-thioxanthyl)propionic acid) in the in vitro neonatal spinal cord and in an in vivo pain model

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About: Evaluation of the activity of a novel metabotropic glutamate receptor antagonist (+/-)-2-amino-2-(3-cis and trans-carboxycyclobutyl-3-(9-thioxanthyl)propionic acid) in the in vitro neonatal spinal cord and in an in vivo pain model Goto Sponge NotDistinct Permalink

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scientific article published on 01 January 2000

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rdf:type	Item
description	wetenschappelijk artikel (nl) wüsseschaftlicher Artikel, wo im Johr 2000 veröffentlicht worden isch (gsw) наукова стаття, опублікована в січні 2000 (uk) im Jahr 2000 veröffentlichter wissenschaftlicher Artikel (de) article scientifique publié en janvier 2000 (fr) artículu científicu espublizáu en xineru de 2000 (ast) artikull shkencor i botuar më 01 janar 2000 (sq) scientific article published on 01 January 2000 (en)
publication date	wds:Q73437046-37CC5573-0D83-48CF-8DCB-EED7E54A3A2B
publication date	2000-01-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q73437046-11C27BFD-241A-4CF1-B278-53FFE31214BD
language of work or name	English
cites work	wds:Q73437046-060FAD62-76DB-498C-87B5-B4285B4F99EB wds:Q73437046-08846FB2-8851-4175-9082-C999162A2DB2 wds:Q73437046-1E93D563-7C65-4AF5-A8C7-1EEE571A7971 wds:Q73437046-2176CB12-0735-4B82-BCF9-2E8DFB930474 wds:Q73437046-2448AD9F-4DB1-4407-AD4B-03A65E37A585 wds:Q73437046-258B5B6B-35E2-4618-AA2F-526DB1ECD0EA wds:Q73437046-2B00F466-09E9-4B8A-8912-614E860957F3 wds:Q73437046-337B3597-0F09-46AB-893B-633FA4D7F0F9 wds:Q73437046-36A1C481-D229-427D-A291-D81CAF7A68C1 wds:Q73437046-49BF5164-EC33-4171-A3AD-7A5D7C148145 wds:Q73437046-4D47225E-5F7A-47C7-AD73-CE016C44D6C6 wds:Q73437046-55DB0746-13D1-4D48-BD6E-478F8FFD8AAC wds:Q73437046-5BEA2B5D-F406-458A-9290-93E6020D90B7 wds:Q73437046-5DF472D5-F7C5-4611-8C43-41EA1CEA72C3 wds:Q73437046-67D79C3A-A9C9-4599-B4F0-4FAF6B7486D2 wds:Q73437046-6C71CEE1-A99F-4442-BBFA-31A13D6B6058 wds:Q73437046-6CB217A0-F7C7-4FA1-B995-8876C7DF9452 wds:Q73437046-7854AC82-7CB4-49F7-870E-F1222B793EE4 wds:Q73437046-844D7DA4-6D51-4C19-B66C-54F943AC66FB wds:Q73437046-88F91735-B69C-4E2F-8278-0E92FF28ED02 wds:Q73437046-89A72333-CC21-4104-86ED-6DF2D947693A wds:Q73437046-AA7F26AA-5012-4CD5-BFDA-A1D07F2E3ED6 wds:Q73437046-AAF44546-2CD9-4060-AF2D-1613520463BD wds:Q73437046-AC062CBE-A30A-4340-AC95-D78060A00ECB wds:Q73437046-AFC0CFC6-1C99-479F-8DB1-739CF6904265 wds:Q73437046-C87011DA-ED08-4AB4-83F1-777F6CD68290 wds:Q73437046-CB3438E8-3B51-4F04-B5A5-23853B665720 wds:Q73437046-CEF1A5B9-EAFC-47CD-93F7-BBE394C8F80B wds:Q73437046-D1C93977-407E-49D1-B79D-2371D3B3A884 wds:Q73437046-D54E53FF-9230-46C6-BEA7-D918830F2B64 wds:Q73437046-EBBED76C-259C-469F-8C28-B054539743E4 wds:Q73437046-EC870DB3-2425-4863-A8F8-EF1DDBBB842C wds:Q73437046-EF4CC4E3-E7CA-4484-8285-BE08E4B5C6C2
cites work	The metabotropic glutamate receptors: structure and functions Distribution of the mRNA for a metabotropic glutamate receptor (mGluR3) in the rat brain: an in situ hybridization study Potent antagonists at the L-AP4- and (1S,3S)-ACPD-sensitive presynaptic metabotropic glutamate receptors in the neonatal rat spinal cord Distribution of the mRNA for a metabotropic glutamate receptor (mGluR1) in the central nervous system: an in situ hybridization study in adult and developing rat Enhanced expression of metabotropic glutamate receptor 3 messenger RNA in the rat spinal cord during ultraviolet irradiation induced peripheral inflammation Potentiation of NMDA and AMPA responses by group I mGluR in spinal cord motoneurons A novel metabotropic glutamate receptor agonist: marked depression of monosynaptic excitation in the newborn rat isolated spinal cord Sensitization of pain pathways in the spinal cord: cellular mechanisms Evidence for presynaptic depression of monosynaptic excitation in neonatal rat motoneurones by (1S,3S)- and (1S,3R)-ACPD Cellular, and subcellular localization of the mGluR5a metabotropic glutamate receptor in rat spinal cord Modulation of AMPA and NMDA responses in rat spinal dorsal horn neurons by trans-1-aminocyclopentane-1,3-dicarboxylic acid Pharmacology of metabotropic glutamate receptor-mediated enhancement of responses to excitatory and inhibitory amino acids on rat spinal neurones in vivo The involvement of metabotropic glutamate receptors and their intracellular signalling pathways in sustained nociceptive transmission in rat dorsal horn neurons Evidence for a role of metabotropic glutamate receptors in sustained nociceptive inputs to rat dorsal horn neurons In vivo antinociceptive activity of anti-rat mGluR1 and mGluR5 antibodies in rats LY341495 is a nanomolar potent and selective antagonist of group II metabotropic glutamate receptors Metabotropic glutamate receptor activation contributes to nociceptive reflex activity in the rat spinal cord in vitro Interactions between metabotropic and ionotropic glutamate receptor agonists in the rat spinal cord in vivo Requirement of metabotropic glutamate receptors for the generation of inflammation-evoked hyperexcitability in rat spinal cord neurons Comparison of nociceptive effects produced by intrathecal administration of mGluR agonists The contribution of metabotropic glutamate receptors (mGluRs) to formalin-induced nociception Antisense ablation of type I metabotropic glutamate receptor mGluR1 inhibits spinal nociceptive transmission Distributions of the mRNAs for L-2-amino-4-phosphonobutyrate-sensitive metabotropic glutamate receptors, mGluR4 and mGluR7, in the rat brain Immunohistochemical localization of a metabotropic glutamate receptor, mGluR5, in the rat brain Metabotropic glutamate receptors depress afferent excitatory transmission in the rat nucleus tractus solitarii Antagonism of presynaptically mediated depressant responses and cyclic AMP-coupled metabotropic glutamate receptors Synaptic excitation of alpha-motoneurons by dorsal root afferents in the neonatal rat spinal cord Phenylglycine derivatives as new pharmacological tools for investigating the role of metabotropic glutamate receptors in the central nervous system. Reduction of sensory and metabotropic glutamate receptor responses in the thalamus by the novel metabotropic glutamate receptor-1-selective antagonist S-2-methyl-4-carboxy-phenylglycine. Mediation of thalamic sensory responses in vivo by ACPD-activated excitatory amino acid receptors. New phenylglycine derivatives with potent and selective antagonist activity at presynaptic glutamate receptors in neonatal rat spinal cord. Novel agonists for metabotropic glutamate receptors: trans- and cis-2-(2-carboxy-3-methoxymethylcyclopropyl)glycine (trans- and cis-MCG-I) mGluR5 immunolocalization in foetal and adult human spinal cord
author name string	wds:Q73437046-302EE531-E0F0-4C51-A5DE-0BCA0DDBA766 wds:Q73437046-4BD0BF55-A378-4C71-8503-F3DFF2B195D9 wds:Q73437046-7B6F4AA6-9F80-4140-BEE7-C1A3A1258557 wds:Q73437046-9745305B-F376-4CA7-AFF7-9F0D29F8B141 wds:Q73437046-A890733A-32AF-4AF7-89DA-00D2FA7554A7 wds:Q73437046-AEDB0079-FDC9-4823-9275-B651D2BCA76D wds:Q73437046-B4E1E885-9E66-4214-9F59-38D930EE3835 wds:Q73437046-C38B3E6C-8056-43D4-AD46-7A513251898B wds:Q73437046-E03F00E7-55AD-444D-B45D-3CD1336C73DA
author name string	Y Chen E Sher R A Wright D D Schoepp B G Johnson A E Kingston B P Clark G Bacon M J Kallman
rdfs:label	Evaluation of the activity of a novel metabotropic glutamate receptor antagonist (nl) Evaluation of the activity of a novel metabotropic glutamate receptor antagonist (+/-)-2-amino-2-(3-cis and trans-carboxycyclobutyl-3-(9-thioxanthyl)propionic acid) in the in vitro neonatal spinal cord and in an in vivo pain model (en) Evaluation of the activity of a novel metabotropic glutamate receptor antagonist (+/-)-2-amino-2-(3-cis and trans-carboxycyclobutyl-3-(9-thioxanthyl)propionic acid) in the in vitro neonatal spinal cord and in an in vivo pain model (sq)

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