About: CD86 (B7-2) on human B cells. A functional role in proliferation and selective differentiation into IgE- and IgG4-producing cells

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About: CD86 (B7-2) on human B cells. A functional role in proliferation and selective differentiation into IgE- and IgG4-producing cells Goto Sponge NotDistinct Permalink

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scientific article published on 01 June 1997

Attributes	Values
rdf:type	Item
description	наукова стаття, опублікована в червні 1997 (uk) im Juni 1997 veröffentlichter wissenschaftlicher Artikel (de) artículu científicu espublizáu en xunu de 1997 (ast) scientific article published on 01 June 1997 (en)
publication date	wds:Q73427456-519F9E0D-8BC0-4E5D-82C9-1A3B80956550
publication date	1997-06-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q73427456-5EA44C36-C27C-4A8C-9803-0731922BD9AC
language of work or name	English
cites work	wds:Q73427456-000B130C-CB75-4378-AC19-ECCF2E617048 wds:Q73427456-01859CF0-35A6-47F7-B61E-0AAAAED0A317 wds:Q73427456-04B4208F-3E4B-4683-AAA0-DCBD29D60560 wds:Q73427456-0717EBC9-5685-4254-9120-393000C505B7 wds:Q73427456-09DB92A1-2EC9-46A3-8A0A-86CAA643403A wds:Q73427456-0AA4469F-DD89-47B0-8805-A9A051AF322D wds:Q73427456-0CAD8258-5025-419D-9A81-5254A1EEBB46 wds:Q73427456-1FAF9EC3-5754-47F4-9761-ED580ACBEF34 wds:Q73427456-25E79406-313F-45F3-BBBB-C6DCBD368FFF wds:Q73427456-27A4D198-DE39-4477-B6B4-4FD3D79C2915 wds:Q73427456-30813F42-C532-4325-A452-67790EDDDFFF wds:Q73427456-353EEF51-0F20-416A-A6A4-D886F20D6D3F wds:Q73427456-55D90401-89DB-4F88-81E4-E12E3BCD2B5A wds:Q73427456-5AAA61F8-D1B7-48F6-BC27-49C39F100E5A wds:Q73427456-5D80405D-EC4E-4FF9-8098-D9C024E21258 wds:Q73427456-6EEB9317-9258-4AED-A230-F36CFE494E52 wds:Q73427456-7915AA87-3A3D-4B28-A261-D18D3E5B7D47 wds:Q73427456-83B2A789-792D-4A47-B75B-52946DA15DC5 wds:Q73427456-8527F67E-FC80-4772-A0B1-6E2DE96CE320 wds:Q73427456-8C0E0AA2-91D5-401B-BFE8-C2E597A4137B wds:Q73427456-8C4BAA6D-14AA-4B45-93FD-C06C49863846 wds:Q73427456-8FEA1D43-0F59-4273-AA0E-D5BE5B880E44 wds:Q73427456-9B0C726F-E9A9-47D6-AB0A-010DF80D71C6 wds:Q73427456-9D0249AB-3DE3-404D-BA32-400815401443 wds:Q73427456-AC35C5B6-679A-4830-B544-19759DDF2669 wds:Q73427456-C354DB73-38D1-4B07-A10B-2B98BA2F7C23 wds:Q73427456-D8771A79-920B-4185-ABAC-D69D91711AE5 wds:Q73427456-E89397FA-F2C6-4340-B2D6-555DA7A17775 wds:Q73427456-F373461B-8B17-4AB8-8878-2EF09F070D8E wds:Q73427456-F4E26B2D-23E6-4E0D-A09E-7DA71BBD722C wds:Q73427456-F8B8C9FA-13EA-4FB4-BE5B-A0DCFDF21F56
cites work	Human CD40-ligand: molecular cloning, cellular distribution and regulation of expression by factors controlling IgE production Cloning of B7-2: a CTLA-4 counter-receptor that costimulates human T cell proliferation Activated human B lymphocytes express three CTLA-4 counterreceptors that costimulate T-cell activation B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy B7-1 and B7-2 do not deliver identical costimulatory signals, since B7-2 but not B7-1 preferentially costimulates the initial production of IL-4. Human recombinant interleukin 4 induces Fc epsilon receptors (CD23) on normal human B lymphocytes. Mice transgenic for a soluble form of murine CTLA-4 show enhanced expansion of antigen-specific CD4+ T cells and defective antibody production in vivo Inhibition of human interleukin 4-induced IgE synthesis by a subset of anti-CD23/Fc epsilon RII monoclonal antibodies Structure and expression of germline epsilon transcripts in human B cells induced by interleukin 4 to switch to IgE production CD21 is a ligand for CD23 and regulates IgE production Immunosuppression in vivo by a soluble form of the CTLA-4 T cell activation molecule CTLA-4 can function as a negative regulator of T cell activation B70/B7-2 is identical to CD86 and is the major functional ligand for CD28 expressed on human dendritic cells Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4 CD28/B7 system of T cell costimulation Interleukin 4 causes isotype switching to IgE in T cell-stimulated clonal B cell cultures CD40 ligand-dependent T cell activation: requirement of B7-CD28 signaling through CD40. CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones Differential T cell costimulatory requirements in CD28-deficient mice B70 antigen is a second ligand for CTLA-4 and CD28. Binding of the B cell activation antigen B7 to CD28 costimulates T cell proliferation and interleukin 2 mRNA accumulation CTLA4 mediates antigen-specific apoptosis of human T cells B cell-B cell interaction through intercellular adhesion molecule-1 and lymphocyte functional antigen-1 regulates immunoglobulin E synthesis by B cells stimulated with interleukin-4 and anti-CD40 antibody CD40 and IgE: synergism between anti-CD40 monoclonal antibody and interleukin 4 in the induction of IgE synthesis by highly purified human B cells Studies on the interdependence of gp39 and B7 expression and function during antigen-specific immune responses Demonstration of a second ligand for the low affinity receptor for immunoglobulin E (CD23) using recombinant CD23 reconstituted into fluorescent liposomes Modulation of IL-4 induced germline epsilon RNA synthesis in human B cells by tumor necrosis factor-alpha, anti-CD40 monoclonal antibodies or transforming growth factor-beta correlates with levels of IgE production Role of interleukin-4 and interleukin-13 in synthesis of IgE and expression of CD23 by human B cells CD28 functions as an adhesion molecule and is involved in the regulation of human IgE synthesis The Epstein-Barr virus-binding site on CD21 is involved in CD23 binding and interleukin-4-induced IgE and IgG4 production by human B cells
author name string	wds:Q73427456-0CDD1444-2DE9-46C1-9C4D-EC1FC316626F wds:Q73427456-9B8A34A8-B1A5-44E7-B90D-B1371BEB1E8A wds:Q73427456-A14102DE-085B-4E58-B77E-B3EEC1E79598 wds:Q73427456-AE9C9FA6-2A13-4225-80F4-409AA43F0440 wds:Q73427456-FA277267-111E-4DCE-B7D0-E36674CB0E86 wds:Q73427456-FE8027BD-0FD6-4FB1-98EB-F42CEEC8FCB4
author name string	J Ellis J Y Bonnefoy J F Gauchat P Jeannin Y Delneste S Lecoanet-Henchoz
rdfs:label	CD86 (B7-2) on human B cells. A functional role in proliferation and selective differentiation into IgE- and IgG4-producing cells (en)
skos:prefLabel	CD86 (B7-2) on human B cells. A functional role in proliferation and selective differentiation into IgE- and IgG4-producing cells (en)
name	CD86 (B7-2) on human B cells. A functional role in proliferation and selective differentiation into IgE- and IgG4-producing cells (en)
title	wds:Q73427456-B0199781-318B-480E-8AE2-459F5FF0A26D
title	CD86 (B7-2) on human B cells. A functional role in proliferation and selective differentiation into IgE- and IgG4-producing cells (en)
page(s)	wds:Q73427456-0FAF8F79-43FC-4DEC-9E64-23D50C57C5B7
page(s)	15613-15619
instance of	wds:Q73427456-D682E9F8-388C-4D63-BFEE-B61FDE10505C
instance of	scholarly article
PubMed ID	wds:Q73427456-7EABB6CA-A54A-448A-85E7-A2BB79064F65
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/9188449
PubMed ID	9188449
published in	wds:Q73427456-D52EA128-0F27-40A6-97CC-3280421F6E1B
published in	Journal of Biological Chemistry
issue	wds:Q73427456-A3EEDF77-7FD4-46AE-9702-39BB3F35BB6A
volume	wds:Q73427456-ECD33842-DCA2-42B7-B0F1-3B8137703EEC
issue	25

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