About: Disease-modifying activity of SB 242235, a selective inhibitor of p38 mitogen-activated protein kinase, in rat adjuvant-induced arthritis

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About: Disease-modifying activity of SB 242235, a selective inhibitor of p38 mitogen-activated protein kinase, in rat adjuvant-induced arthritis Goto Sponge NotDistinct Permalink

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scientific article published on 01 January 2000

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rdf:type	Item
description	wetenschappelijk artikel (nl) wüsseschaftlicher Artikel, wo im Johr 2000 veröffentlicht worden isch (gsw) наукова стаття, опублікована в січні 2000 (uk) im Jahr 2000 veröffentlichter wissenschaftlicher Artikel (de) artículu científicu espublizáu en xineru de 2000 (ast) articolo scientifico (pubblicato il 2000) (it) artikull shkencor i botuar më 01 janar 2000 (sq) scientific article published on 01 January 2000 (en)
publication date	wds:Q73374754-248CA6F1-BECC-41AE-8008-8F352CCAFD0E
publication date	2000-01-01 00:00:00Z (xsd:dateTime)
cites work	wds:Q73374754-10137EBA-DC23-47DC-8601-3595D59E83DF wds:Q73374754-1995335D-02DD-4153-BF37-3E96A586C51B wds:Q73374754-2BD7013C-D168-4340-BE1F-EE2F3F2BC1F4 wds:Q73374754-5A988588-04D1-421F-95A1-F0E4EF1792FA wds:Q73374754-5E623D27-A388-4381-B205-57D31569B9E9 wds:Q73374754-66412393-A440-4D39-A1AF-E7BF71A72B6C wds:Q73374754-696EB6B1-0AC8-4B43-B476-B55B61C23124 wds:Q73374754-7ABF0E13-1068-4992-B57D-BD78576C6B6B wds:Q73374754-7BE6BD52-F795-4365-B7B2-73ECFD65DD79 wds:Q73374754-8677B82C-2D59-4B79-BDDB-E3A8DCADFABC wds:Q73374754-88725858-0F14-455D-B09D-7FC3EB469F72 wds:Q73374754-8F0A780B-4F24-4D6A-B1AF-E9D777A6688C wds:Q73374754-93CDB1CB-68A6-46F8-8A89-C54B29AD6E11 wds:Q73374754-9ACE025B-D84C-4327-8040-1A6B4D21B3F0 wds:Q73374754-A1DE5C5B-B09E-4A91-B784-299F0E414553 wds:Q73374754-A7563FCD-D79B-4D85-B80D-BEF43665CD58 wds:Q73374754-AA31BC83-914B-436B-84BC-D1585450A151 wds:Q73374754-AE028835-8D76-4CBD-B2D9-26E16EF02C2A wds:Q73374754-AF0FC066-1FFD-4F43-9724-C706318EAC6B wds:Q73374754-CFFE73FC-7546-4EFD-86A2-3131DC408135 wds:Q73374754-D29A0BF4-C326-416E-BED5-D63C5F836DEB wds:Q73374754-D52CE8BA-13D6-4677-B537-22F41767331C wds:Q73374754-E635468A-00C5-487F-A50E-7048481FA7D4 wds:Q73374754-E8196272-8588-495B-9443-F125FA846884 wds:Q73374754-E8F93C07-42D3-4D81-8408-308F50CCA493 wds:Q73374754-FB03D1A6-ADF3-4451-A953-F9E260F24C39
cites work	SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1 A protein kinase involved in the regulation of inflammatory cytokine biosynthesis A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells p38 mitogen-activated protein kinase inhibitors--mechanisms and therapeutic potentials Direct Inhibition of Cyclooxygenase-1 and -2 by the Kinase Inhibitors SB 203580 and PD 98059 Pyridinyl imidazoles inhibit the inflammatory phase of delayed type hypersensitivity reactions without affecting T-dependent immune responses Interleukin-6 (IL-6) in synovial fluid and serum of patients with rheumatic diseases Interleukin-6 in synovial fluid and serum of patients with rheumatoid arthritis and other inflammatory arthritides Novel homologues of CSBP/p38 MAP kinase: activation, substrate specificity and sensitivity to inhibition by pyridinyl imidazoles A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins Interleukin-1 activates a novel protein kinase cascade that results in the phosphorylation of Hsp27. Cytokines and cytokine inhibitors or antagonists in rheumatoid arthritis Pyridinyl imidazole inhibitors of p38 mitogen-activated protein kinase bind in the ATP site Inflammatory cytokines: interleukin-1 and tumor necrosis factor as effector molecules in autoimmune diseases Excessive production of interleukin 6/B cell stimulatory factor-2 in rheumatoid arthritis Structural basis of inhibitor selectivity in MAP kinases Pyrroles and other heterocycles as inhibitors of p38 kinase 1-substituted 4-aryl-5-pyridinylimidazoles: a new class of cytokine suppressive drugs with low 5-lipoxygenase and cyclooxygenase inhibitory potency Cytokines and other mediators in rheumatoid arthritis Effect of inhibitors of eicosanoid metabolism in murine collagen-induced arthritis Insights into the role of nitric oxide in inflammatory arthritis Role of cytokines in the regulation of bone resorption New directions for biological therapy in rheumatoid arthritis Biologic agents for treating rheumatoid arthritis. Concepts and progress Pharmacology of the pyrroloimidazole, SK&F 105809--I. Inhibition of inflammatory cytokine production and of 5-lipoxygenase- and cyclooxygenase-mediated metabolism of arachidonic acid Microprocessor-assisted plethysmograph for the measurement of mouse paw volume
author name string	wds:Q73374754-2BCA18B2-05B5-439F-84C8-05BF22324A0F wds:Q73374754-33034F40-B667-424A-B6D5-437B0CB444AE wds:Q73374754-48E38E89-186F-4786-934C-EF9A6D97D66D wds:Q73374754-4A624EC5-10C8-4A02-BCC3-15EBABD3AF65 wds:Q73374754-62F5649F-A617-4690-95C7-ECE56E4ABC1C wds:Q73374754-73D2FB51-163B-4FA0-AC2B-5EEE9FC82F25 wds:Q73374754-7E7EA72E-0179-43F6-AB2D-C484A0BC5EE9 wds:Q73374754-BE4CBCBB-666A-45C4-932F-4AEC36788B1D wds:Q73374754-C948D0B3-0263-4F76-B483-CF59AB84BCBE wds:Q73374754-D5F3A8CF-5BC7-4618-B338-1F8BBBA3276C wds:Q73374754-DA1409B3-F37E-4E4B-A123-1A0D84B45B39 wds:Q73374754-E60D3A1A-CFE4-48DB-BB26-9269A9D76259 wds:Q73374754-EA71C5E2-0464-4C4C-A547-4C00B8709EF1
author name string	Blake S Adams JL Lee JC Badger AM Hoffman SJ Boehm JC Griswold DE Gowen M Rieman DJ Stroup GB Webb E Kapadia R Swift BA
rdfs:label	Disease-modifying activity of SB 242235, a selective inhibitor of p38 mitogen-activated protein kinase, in rat adjuvant-induced arthritis (en) Disease-modifying activity of SB 242235, a selective inhibitor of p38 mitogen-activated protein kinase, in rat adjuvant-induced arthritis (nl) Disease-modifying activity of SB 242235, a selective inhibitor of p38 mitogen-activated protein kinase, in rat adjuvant-induced arthritis (sq)
skos:prefLabel	Disease-modifying activity of SB 242235, a selective inhibitor of p38 mitogen-activated protein kinase, in rat adjuvant-induced arthritis (en) Disease-modifying activity of SB 242235, a selective inhibitor of p38 mitogen-activated protein kinase, in rat adjuvant-induced arthritis (nl) Disease-modifying activity of SB 242235, a selective inhibitor of p38 mitogen-activated protein kinase, in rat adjuvant-induced arthritis (sq)
name	Disease-modifying activity of SB 242235, a selective inhibitor of p38 mitogen-activated protein kinase, in rat adjuvant-induced arthritis (en) Disease-modifying activity of SB 242235, a selective inhibitor of p38 mitogen-activated protein kinase, in rat adjuvant-induced arthritis (nl) Disease-modifying activity of SB 242235, a selective inhibitor of p38 mitogen-activated protein kinase, in rat adjuvant-induced arthritis (sq)
title	wds:Q73374754-1C434508-C1FB-444D-BB1D-E3FE7E53B684
title	Disease-modifying activity of SB 242235, a selective inhibitor of p38 mitogen-activated protein kinase, in rat adjuvant-induced arthritis (en)

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