About: Tetrahydrobiopterin improves endothelium-dependent vasodilation by increasing nitric oxide activity in patients with Type II diabetes mellitus

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About: Tetrahydrobiopterin improves endothelium-dependent vasodilation by increasing nitric oxide activity in patients with Type II diabetes mellitus Goto Sponge NotDistinct Permalink

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scientific article published on 01 November 2000

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в листопаді 2000 (uk) im November 2000 veröffentlichter wissenschaftlicher Artikel (de) artículu científicu espublizáu en payares de 2000 (ast) scientific article published on 01 November 2000 (en)
publication date	wds:Q73318912-1AB7FC85-F1C0-45E7-8CAA-EA7DDD2BAFCB
publication date	2000-11-01 00:00:00Z (xsd:dateTime)
exact match	wds:Q73318912-8B97D537-D939-4CDC-95D8-CD7DC28ADBB2
exact match	https://scigraph.springernature.com/pub.10.1007/s001250051551
author name string	wds:Q73318912-912559C3-C2AB-49E0-A810-6DF80FBA36B9 wds:Q73318912-D59B886A-96C5-4F68-AB74-E2CBAB20FD4A wds:Q73318912-DB337D57-3F16-47AD-8DE2-D03A792B787B wds:Q73318912-F5ECB952-ABD6-43C4-B4B5-7DABD81E112C
author name string	Meinertz T Krohn K Albers S Heitzer T
rdfs:label	Tetrahydrobiopterin improves endothelium-dependent vasodilation by increasing nitric oxide activity in patients with Type II diabetes mellitus (en) Tetrahydrobiopterin improves endothelium-dependent vasodilation by increasing nitric oxide activity in patients with Type II diabetes mellitus (nl)
skos:prefLabel	Tetrahydrobiopterin improves endothelium-dependent vasodilation by increasing nitric oxide activity in patients with Type II diabetes mellitus (en) Tetrahydrobiopterin improves endothelium-dependent vasodilation by increasing nitric oxide activity in patients with Type II diabetes mellitus (nl)
name	Tetrahydrobiopterin improves endothelium-dependent vasodilation by increasing nitric oxide activity in patients with Type II diabetes mellitus (en) Tetrahydrobiopterin improves endothelium-dependent vasodilation by increasing nitric oxide activity in patients with Type II diabetes mellitus (nl)
title	wds:Q73318912-7218E41D-F7F8-4DD3-92CA-FAE3733400F0
title	Tetrahydrobiopterin improves endothelium-dependent vasodilation by increasing nitric oxide activity in patients with Type II diabetes mellitus (en)
page(s)	wds:Q73318912-1DDDF9F9-6D98-4928-9BFB-CD79BE4DE12A
page(s)	1435-1438
instance of	wds:Q73318912-144AD09E-158C-4FEA-9A70-3F1405A4947C
instance of	scholarly article
main subject	wds:Q73318912-2873F0EC-0704-40D8-9012-276621E33EBF wds:Q73318912-D73124E5-DE01-4085-A208-86BE6E05F5BC
main subject	sapropterin type 2 diabetes
PubMed ID	wds:Q73318912-77619A80-FB75-449F-A541-1FC218422368
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/11126415
PubMed ID	11126415
published in	wds:Q73318912-A0E277B7-F907-4555-A7DA-C9A3F1837B80
published in	Diabetologia
issue	wds:Q73318912-FD04F6F7-5A60-48F3-A84B-C8165F10568D
volume	wds:Q73318912-7A6AB2F9-4277-43BB-9982-1C800BCA3010
issue	11
volume	43
DOI	wds:Q73318912-CB2331CA-57E2-43BC-8D90-D3699C83B15F
DOI	http://dx.doi.org/10.1007/S001250051551
DOI	10.1007/S001250051551
Dimensions Publication ID	wds:Q73318912-868D2A78-01CC-4482-ACC6-8CD54FA83464
Dimensions Publication ID	1026364042
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q73318912
is cites work of	Tetrahydrobiopterin protects the kidney from ischemia-reperfusion injury Animal products, diseases and drugs: a plea for better integration between agricultural sciences, human nutrition and human pharmacology Targeting endothelial dysfunction in vascular complications associated with diabetes Tetrahydrobiopterin improves endothelial function and decreases arterial stiffness in estrogen-deficient postmenopausal women Tetrahydrobiopterin corrects Escherichia coli endotoxin-induced endothelial dysfunction Endothelium-dependent contractions and endothelial dysfunction in human hypertension Tetrahydrobiopterin-dependent preservation of nitric oxide-mediated endothelial function in diabetes by targeted transgenic GTP-cyclohydrolase I overexpression The clinical implications of endothelial dysfunction Vascular protection by tetrahydrobiopterin: progress and therapeutic prospects Folic acid says NO to vascular diseases Vascular nitric oxide: Beyond eNOS Renal endothelial dysfunction in diabetic nephropathy Therapeutic effect of enhancing endothelial nitric oxide synthase (eNOS) expression and preventing eNOS uncoupling Endothelial dysfunction and diabetes: effects on angiogenesis, vascular remodeling, and wound healing Recoupling the cardiac nitric oxide synthases: tetrahydrobiopterin synthesis and recycling Systemic and vascular oxidation limits the efficacy of oral tetrahydrobiopterin treatment in patients with coronary artery disease The regulation of vascular tetrahydrobiopterin bioavailability Cardiac-specific overexpression of GTP cyclohydrolase 1 restores ischaemic preconditioning during hyperglycaemia Nitric oxide and oxidative stress in vascular disease Macrovascular angiopathy in children and adolescents with type 1 diabetes. ADMA and oxidative stress Mechanisms, significance and treatment of vascular dysfunction in type 2 diabetes mellitus: focus on lipid-regulating therapy. Nitric oxide synthases: regulation and function Principles of targeting endothelial cell metabolism to treat angiogenesis and endothelial cell dysfunction in disease Tetrahydrobiopterin in cardiovascular health and disease Tetrahydrobiopterin improves endothelial function in cardiovascular disease: a systematic review Nitric oxide, atherosclerosis and the clinical relevance of endothelial dysfunction Synthesis and recycling of tetrahydrobiopterin in endothelial function and vascular disease Recent developments in the effects of nitric oxide-donating statins on cardiovascular disease through regulation of tetrahydrobiopterin and nitric oxide Exercise restores endothelial function independently of weight loss or hyperglycaemic status in db/db mice. Targeting vascular (endothelial) dysfunction. Insulin resistance and endothelial dysfunction The ratio between tetrahydrobiopterin and oxidized tetrahydrobiopterin analogues controls superoxide release from endothelial nitric oxide synthase: an EPR spin trapping study The nitric oxide pathway in the cardiovascular system. eNOS function is developmentally regulated: uncoupling of eNOS occurs postnatally. Nutritional regulation of insulin secretion: implications for diabetes Cellular basis of endothelial dysfunction in small mesenteric arteries from spontaneously diabetic (db/db -/-) mice: role of decreased tetrahydrobiopterin bioavailability An integrated view of insulin resistance and endothelial dysfunction Targeting Nitric Oxide with Natural Derived Compounds as a Therapeutic Strategy in Vascular Diseases Oxidation of the zinc-thiolate complex and uncoupling of endothelial nitric oxide synthase by peroxynitrite The role of reactive oxygen species in microvascular remodeling Endothelial dysfunction in diabetic erectile dysfunction Exercise training enhanced myocardial endothelial nitric oxide synthase (eNOS) function in diabetic Goto-Kakizaki (GK) rats Role of insulin resistance in endothelial dysfunction Mechanisms of Disease: endothelial dysfunction in insulin resistance and diabetes Oxidative stress in vascular disease: causes, defense mechanisms and potential therapies Modeling of biopterin-dependent pathways of eNOS for nitric oxide and superoxide production. The vascular endothelium in diabetes--a therapeutic target? Tetrahydrobiopterin has a glucose-lowering effect by suppressing hepatic gluconeogenesis in an endothelial nitric oxide synthase-dependent manner in diabetic mice. Peroxynitrite-dependent zinc release and inactivation of guanosine 5'-triphosphate cyclohydrolase 1 instigate its ubiquitination in diabetes. Improvement of endothelial nitric oxide synthase activity retards the progression of diabetic nephropathy in db/db mice

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