About: The evolutionarily conserved N-terminal region of Cbl is sufficient to enhance down-regulation of the epidermal growth factor receptor

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About: The evolutionarily conserved N-terminal region of Cbl is sufficient to enhance down-regulation of the epidermal growth factor receptor Goto Sponge NotDistinct Permalink

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scientific article published on 01 January 2000

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) wüsseschaftlicher Artikel, wo im Johr 2000 veröffentlicht worden isch (gsw) наукова стаття, опублікована в січні 2000 (uk) im Januar 2000 veröffentlichter wissenschaftlicher Artikel (de) artículu científicu espublizáu en xineru de 2000 (ast) articolo scientifico (pubblicato il 2000) (it) artikull shkencor i botuar më 01 janar 2000 (sq) scientific article published on 01 January 2000 (en)
publication date	wds:Q73316781-4F0B9318-0B6B-4975-95A8-C018A77987BC
publication date	2000-01-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q73316781-D0133368-6448-4F46-BF0B-1B1D1B831753
language of work or name	English
cites work	wds:Q73316781-043928FF-3D06-4524-9DB7-4D1CB25931F3 wds:Q73316781-4578E393-62B8-4C7F-A80F-344C99455143
cites work	Characteristics of a human cell line transformed by DNA from human adenovirus type 5 SV40-transformed simian cells support the replication of early SV40 mutants
author name string	wds:Q73316781-01834E29-6769-4F01-A787-B31456A08A94 wds:Q73316781-16B439C2-2C25-44DA-B50D-CCE407E0007C wds:Q73316781-32AAAB8B-C1D2-4C2D-A0A1-33FB08B89282 wds:Q73316781-48134367-DC46-4EDF-BFC6-A8FEA362DFA3 wds:Q73316781-549D6FC2-199B-4FE0-90C1-45AB0B29E470 wds:Q73316781-65FB7D09-4F86-4DC3-926F-B77D32FFAD96 wds:Q73316781-6DAED235-17D2-4B54-BC56-74C6EF327389 wds:Q73316781-BA4A1D74-18C8-4E63-853F-F0928D1DE531 wds:Q73316781-C9D6209B-3AE6-4E1D-A9EE-2C3446A8158E
author name string	H Band S Miyake V W Hsu S Ota M L Lupher N L Lill P Douillard N Meissner-Lula R A Awwad
rdfs:label	The evolutionarily conserved N-terminal region of Cbl is sufficient to enhance down-regulation of the epidermal growth factor receptor (en) The evolutionarily conserved N-terminal region of Cbl is sufficient to enhance down-regulation of the epidermal growth factor receptor (nl) The evolutionarily conserved N-terminal region of Cbl is sufficient to enhance down-regulation of the epidermal growth factor receptor (sq)
skos:prefLabel	The evolutionarily conserved N-terminal region of Cbl is sufficient to enhance down-regulation of the epidermal growth factor receptor (en) The evolutionarily conserved N-terminal region of Cbl is sufficient to enhance down-regulation of the epidermal growth factor receptor (nl) The evolutionarily conserved N-terminal region of Cbl is sufficient to enhance down-regulation of the epidermal growth factor receptor (sq)
name	The evolutionarily conserved N-terminal region of Cbl is sufficient to enhance down-regulation of the epidermal growth factor receptor (en) The evolutionarily conserved N-terminal region of Cbl is sufficient to enhance down-regulation of the epidermal growth factor receptor (nl) The evolutionarily conserved N-terminal region of Cbl is sufficient to enhance down-regulation of the epidermal growth factor receptor (sq)
title	wds:Q73316781-4D636393-2462-423E-A473-3E66FC8BCD91
title	The evolutionarily conserved N-terminal region of Cbl is sufficient to enhance down-regulation of the epidermal growth factor receptor (en)
page(s)	wds:Q73316781-7AEC686F-7166-4DB4-ADDC-489410BFA2CE
page(s)	367-377
instance of	wds:Q73316781-28E9DE40-3E76-4D1D-A5E5-712B1A117371
instance of	scholarly article
PubMed ID	wds:Q73316781-B401BEA3-0DCC-4200-8A63-F0B56FA0E8B3
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/10617627
PubMed ID	10617627
published in	wds:Q73316781-1BBA4562-7393-4B20-823C-6CE555104F3E
published in	Journal of Biological Chemistry
issue	wds:Q73316781-1E721A79-784C-47DB-AC9F-34F85448580C
volume	wds:Q73316781-1402A3CA-1460-4370-85CE-AB2C3AFA2A88
issue	1
volume	275
DOI	wds:Q73316781-7D067775-D764-48D0-9C4A-C09D436042C8
DOI	http://dx.doi.org/10.1074/JBC.275.1.367
DOI	10.1074/JBC.275.1.367
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q73316781
is cites work of	Hse1, a component of the yeast Hrs-STAM ubiquitin-sorting complex, associates with ubiquitin peptidases and a ligase to control sorting efficiency into multivesicular bodies EphA2/Ephrin-A1 signaling complexes restrict corneal epithelial cell migration. E1A-mediated suppression of EGFR expression and induction of apoptosis in head and neck squamous carcinoma cell lines Mutation of the c-Cbl TKB domain binding site on the Met receptor tyrosine kinase converts it into a transforming protein RING finger mutations that abolish c-Cbl-directed polyubiquitination and downregulation of the EGF receptor are insufficient for cell transformation Ubiquitination and proteasomal activity is required for transport of the EGF receptor to inner membranes of multivesicular bodies Abi-1 forms an epidermal growth factor-inducible complex with Cbl: role in receptor endocytosis Cbl: many adaptations to regulate protein tyrosine kinases Ubiquitination of fibroblast growth factor receptor 1 is required for its intracellular sorting but not for its endocytosis Cbl-dependent ubiquitination is required for progression of EGF receptors into clathrin-coated pits c-Cbl and Cbl-b ubiquitin ligases: substrate diversity and the negative regulation of signalling responses Cbl-mediated Ubiquitinylation Is Required for Lysosomal Sorting of Epidermal Growth Factor Receptor but Is Dispensable for Endocytosis Epidermal growth factor receptor internalization through clathrin-coated pits requires Cbl RING finger and proline-rich domains but not receptor polyubiquitylation The non-receptor tyrosine kinase Syk is a target of Cbl-mediated ubiquitylation upon B-cell receptor stimulation. Cbl-b interacts with ubiquitinated proteins; differential functions of the UBA domains of c-Cbl and Cbl-b Regulation of Membrane Protein Transport by Ubiquitin and Ubiquitin-Binding Proteins Mechanism of the spatio-temporal regulation of Ras and Rap1. Regulation of CXCR4-mediated chemotaxis and chemoinvasion of breast cancer cells A tale of two Cbls: interplay of c-Cbl and Cbl-b in epidermal growth factor receptor downregulation Direct interaction of Cbl with pTyr 1045 of the EGF receptor (EGFR) is required to sort the EGFR to lysosomes for degradation Lateral propagation of EGF signaling after local stimulation is dependent on receptor density. Phosphorylation of the platelet-derived growth factor receptor-beta and epidermal growth factor receptor by G protein-coupled receptor kinase-2. Mechanisms for selectivity of desensitization Sorting in the endosomal system in yeast and animal cells. Huntingtin-associated protein 1 interacts with hepatocyte growth factor-regulated tyrosine kinase substrate and functions in endosomal trafficking A mutant EGF-receptor defective in ubiquitylation and endocytosis unveils a role for Grb2 in negative signaling Epidermal growth factor receptor fate is controlled by Hrs tyrosine phosphorylation sites that regulate Hrs degradation Neuregulin-induced ErbB3 downregulation is mediated by a protein stability cascade involving the E3 ubiquitin ligase Nrdp1 E3 ubiquitin ligases in ErbB receptor quantity control Phosphotyrosine-binding domains in signal transduction An ACAP1-containing clathrin coat complex for endocytic recycling TULA: an SH3- and UBA-containing protein that binds to c-Cbl and ubiquitin CBL is frequently altered in lung cancers: its relationship to mutations in MET and EGFR tyrosine kinases Direct binding of Cbl to Tyr568 and Tyr936 of the stem cell factor receptor/c-Kit is required for ligand-induced ubiquitination, internalization and degradation. The Cbl proto-oncogene product negatively regulates the Src-family tyrosine kinase Fyn by enhancing its degradation Beyond the RING: CBL proteins as multivalent adapters Localization and modulation of ErbB receptor tyrosine kinases Ligand-specific sequential regulation of transcription factors for differentiation of MCF-7 cells

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