About: Expression of cell-cycle regulators p27Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients

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About: Expression of cell-cycle regulators p27Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients Goto Sponge NotDistinct Permalink

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scientific article published on 01 February 1997

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в лютому 1997 (uk) article scientifique publié en 1997 (fr) im Februar 1997 veröffentlichter wissenschaftlicher Artikel (de) artículu científicu espublizáu en febreru de 1997 (ast) artikull shkencor i botuar më 01 shkurt 1997 (sq) scientific article published on 01 February 1997 (en)
publication date	wds:Q73034313-4ACF083F-9F16-4923-8C01-57450B74F9D7
publication date	1997-02-01 00:00:00Z (xsd:dateTime)
exact match	wds:Q73034313-F03FEBE0-3F52-48B6-AAC9-5D7791B2BCE9
exact match	https://scigraph.springernature.com/pub.10.1038/nm0297-222
cites work	wds:Q73034313-0F7B0B39-0A1D-44AB-A94B-915143E353EA wds:Q73034313-215F8F7F-65CB-48DD-A201-975FA49BA450 wds:Q73034313-232DFEEE-9B8C-4416-9632-3F23614D5F2C wds:Q73034313-2D634AEB-2B08-4569-91E8-EAF5570A3E79 wds:Q73034313-353AEA39-69BC-4443-971B-FE4DB5161573 wds:Q73034313-4F519017-F29D-45BF-A3D8-38DCB57A7601 wds:Q73034313-649FF1B1-9414-4A87-BDE1-DF8EBBFBD08E wds:Q73034313-65C93DDF-619B-4331-A486-8E169768952A wds:Q73034313-754C4AE3-5FAD-4E50-922B-DE3FC575E347 wds:Q73034313-BEF965A0-30C7-40DC-96F7-2A22DD361DC7 wds:Q73034313-C17D5D0F-A7A4-4D79-8534-DCA76F676F0B wds:Q73034313-E1B64487-4824-489B-825B-28619E09DE38 wds:Q73034313-F59CBCC7-F433-47B9-B3D2-DC2C8C260540 wds:Q73034313-FF76AEF0-AAC4-4715-9910-D595E93422BF
cites work	Human cyclin E, a nuclear protein essential for the G1-to-S phase transition Human cyclin E, a new cyclin that interacts with two members of the CDC2 gene family. Cyclin-dependent regulation of G1 in mammalian fibroblasts. Turnover of cyclin E by the ubiquitin-proteasome pathway is regulated by cdk2 binding and cyclin phosphorylation Interleukin-2-mediated elimination of the p27Kip1 cyclin-dependent kinase inhibitor prevented by rapamycin Cell cyclins and cyclin-dependent kinase activities in mouse mammary tumor development. Cyclins as markers of tumor proliferation: immunocytochemical studies in breast cancer Prognostic factors and treatment decisions in axillary-node-negative breast cancer Association of human cyclin E with a periodic G1-S phase protein kinase Immunohistological detection of tumour growth fraction (Ki-67 antigen) in formalin-fixed and routinely processed tissues A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice Requirement of p27Kip1 for restriction point control of the fibroblast cell cycle Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27 Cell cycle and cancer
author name string	wds:Q73034313-1449C253-3E53-42C7-895A-A1A26E848F1B wds:Q73034313-1F471E95-D0E1-4C32-BD4F-AB4D5CAE95F3 wds:Q73034313-5FC313C1-0128-46BC-9D47-AF82A19E9B93 wds:Q73034313-B904ADE1-9CA7-425E-8B86-F32E576011E2 wds:Q73034313-D22225F6-844C-45E7-AC09-0C89688767CA
author name string	J M Roberts P J Heagerty E J Firpo G M Alexander L A Gatti
rdfs:label	Expression of cell-cycle regulators p27Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients (en) Expression of cell-cycle regulators p27Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients (nl) Expression of cell-cycle regulators p27Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients (sq)
skos:prefLabel	Expression of cell-cycle regulators p27Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients (en) Expression of cell-cycle regulators p27Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients (nl) Expression of cell-cycle regulators p27Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients (sq)
name	Expression of cell-cycle regulators p27Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients (en) Expression of cell-cycle regulators p27Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients (nl) Expression of cell-cycle regulators p27Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients (sq)
author	wds:Q73034313-844572D4-C307-4840-9A9D-9489DC8F95CD wds:Q73034313-B84BA6DE-D799-4EAC-9B21-B939FD2D1EB4 wds:Q73034313-F49E76B9-757F-4749-9F97-5BA78476F77E
author	Janet Daling Kathleen E. Malone Peggy L. Porter
title	wds:Q73034313-F8DBB627-E996-469F-AA03-B8EE92B04B56
title	Expression of cell-cycle regulators p27Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients (en)
page(s)	wds:Q73034313-553D0A55-6CC5-4B2A-A19B-987E1D8093F6
page(s)	222-225
instance of	wds:Q73034313-3EC6042F-68BA-41D7-9B21-E3E8CB93D7EB
instance of	scholarly article
main subject	wds:Q73034313-DBADFD3E-86B2-4164-A823-2DBB0D8B5536
main subject	breast cancer
PubMed ID	wds:Q73034313-B6A53FE7-4EB6-4A68-8AEF-34FFE74D7281
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/9018243
PubMed ID	9018243
published in	wds:Q73034313-D2D91B42-CB5B-471E-BBD6-A1F62875C511
published in	Nature Medicine
issue	wds:Q73034313-91EC2517-5426-4425-AED8-F5AE8543365A
volume	wds:Q73034313-CE4EFFCA-A443-43D5-A7EE-852A6394E1F5
issue	2
volume	3
DOI	wds:Q73034313-22EEF01B-0697-4F25-8140-DCD9704302CF
DOI	http://dx.doi.org/10.1038/NM0297-222
DOI	10.1038/NM0297-222
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q73034313
is cites work of	Green tea extracts decrease carcinogen-induced mammary tumor burden in rats and rate of breast cancer cell proliferation in culture. Differential role of beta(1C) and beta(1A) integrin cytoplasmic variants in modulating focal adhesion kinase, protein kinase B/AKT, and Ras/Mitogen-activated protein kinase pathways Reduced expression of cyclin-dependent kinase inhibitor p27Kip1 is associated with advanced stage and invasiveness of gastric carcinomas. G1-S transition defects occur in most breast cancers and predict outcome A NIK-IKKα module expands ErbB2-induced tumor-initiating cells by stimulating nuclear export of p27/Kip1 Cyclins and breast cancer A new pathway for mitogen-dependent cdk2 regulation uncovered in p27(Kip1)-deficient cells Foxm1b transcription factor is essential for development of hepatocellular carcinomas and is negatively regulated by the p19ARF tumor suppressor C-erbB-2 overexpression and survival in early onset breast cancer Frequent loss of PTEN expression is linked to elevated phosphorylated Akt levels, but not associated with p27 and cyclin D1 expression, in primary epithelial ovarian carcinomas Loss of CBP causes T cell lymphomagenesis in synergy with p27Kip1 insufficiency. Cell cycle proteins as promising targets in cancer therapy Transforming growth factor-beta signal transduction in epithelial cells. Decreased p27(Kip1) expression and cyclin D1 overexpression, alone and in combination, influence recurrence and survival of patients with resectable extrahepatic bile duct carcinoma

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