About: The human cytomegalovirus 86K immediate early (IE) 2 protein requires the basic region of the TATA-box binding protein (TBP) for binding, and interacts with TBP and transcription factor TFIIB via regions of IE2 required for transcriptional regulatio

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About: The human cytomegalovirus 86K immediate early (IE) 2 protein requires the basic region of the TATA-box binding protein (TBP) for binding, and interacts with TBP and transcription factor TFIIB via regions of IE2 required for transcriptional regulatio Goto Sponge NotDistinct Permalink

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scientific article published on 01 December 1993

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в грудні 1993 (uk) 1993 ഡിസംബര്‍ 1 നു പ്രസിദ്ധീകരിച്ച ശാസ്ത്ര ലേഖനം (ml) article scientifique publié en 1993 (fr) im Dezember 1993 veröffentlichter wissenschaftlicher Artikel (de) artículu científicu espublizáu n'avientu de 1993 (ast) scientific article published on 01 December 1993 (en)
publication date	wds:Q72696029-39A00D28-371D-4E67-8CD4-396548BA20C6
publication date	1993-12-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q72696029-B933BC9C-A1AF-42B2-B403-ED435E3B8AEF
language of work or name	English
author name string	wds:Q72696029-113C1E78-1633-4F1A-AA29-D6B1F63F8955 wds:Q72696029-4F9FD5D4-C474-4871-B736-F93A3F20B968 wds:Q72696029-99A5E27A-8B23-4D04-BA6C-1C9ABC742BE0 wds:Q72696029-A6E59248-B08E-43DE-879A-829DB6C63876 wds:Q72696029-C154840B-88F9-49A9-B713-ED1979120BA8
author name string	T Kouzarides G Hayward J Sinclair C Hagemeier C J Chiou
rdfs:label	The human cytomegalovirus 86K immediate early (IE) 2 protein requires the basic region of the TATA-box binding protein (TBP) for binding, and interacts with TBP and transcription factor TFIIB via regions of IE2 required for transcriptional regulatio (en) The human cytomegalovirus 86K immediate early (IE) 2 protein requires the basic region of the TATA-box binding protein (TBP) for binding, and interacts with TBP and transcription factor TFIIB via regions of IE2 required for transcriptional regulatio (nl)
skos:prefLabel	The human cytomegalovirus 86K immediate early (IE) 2 protein requires the basic region of the TATA-box binding protein (TBP) for binding, and interacts with TBP and transcription factor TFIIB via regions of IE2 required for transcriptional regulatio (en) The human cytomegalovirus 86K immediate early (IE) 2 protein requires the basic region of the TATA-box binding protein (TBP) for binding, and interacts with TBP and transcription factor TFIIB via regions of IE2 required for transcriptional regulatio (nl)
name	The human cytomegalovirus 86K immediate early (IE) 2 protein requires the basic region of the TATA-box binding protein (TBP) for binding, and interacts with TBP and transcription factor TFIIB via regions of IE2 required for transcriptional regulatio (en) The human cytomegalovirus 86K immediate early (IE) 2 protein requires the basic region of the TATA-box binding protein (TBP) for binding, and interacts with TBP and transcription factor TFIIB via regions of IE2 required for transcriptional regulatio (nl)
author	wds:Q72696029-52EC8BDF-7E59-4BB8-BBEC-AAC2A8A2701E wds:Q72696029-9D692F7D-34CB-4F21-ACF3-A448F5EA6244
author	Tony Kouzarides Richard Caswell
title	wds:Q72696029-4D36B92F-7203-478F-81CD-C07F43A1C1EE
title	The human cytomegalovirus 86K immediate early (IE) 2 protein requires the basic region of the TATA-box binding protein (TBP) for binding, and interacts with TBP and transcription factor TFIIB via regions of IE2 required for transcriptional regulation (en)
page(s)	wds:Q72696029-0529D3F8-01D1-4B60-8450-2291C31E2296
page(s)	2691-2698
instance of	wds:Q72696029-3AF709A5-F5EA-4755-8B56-D56D7602C909
instance of	scholarly article
PubMed ID	wds:Q72696029-0DCE210A-DCC1-4B50-8D13-97EFC067AF3C
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/8277274
PubMed ID	8277274
published in	wds:Q72696029-FF7CAC43-C078-4882-8B1C-897B71EF3242
published in	Journal of General Virology
volume	wds:Q72696029-DCDADF8E-2153-4797-9F66-01E7E0EDFEBC
volume	74 ( Pt 12)
DOI	wds:Q72696029-D699C990-9A88-4927-8335-6FB0DCB98451
DOI	http://dx.doi.org/10.1099/0022-1317-74-12-2691
DOI	10.1099/0022-1317-74-12-2691
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q72696029
is cites work of	Effect of the human cytomegalovirus IE86 protein on expression of E2F-responsive genes: a DNA microarray analysis The human cytomegalovirus IE1-72 protein interacts with the cellular p107 protein and relieves p107-mediated transcriptional repression of an E2F-responsive promoter. Defective growth correlates with reduced accumulation of a viral DNA replication protein after low-multiplicity infection by a human cytomegalovirus ie1 mutant The human cytomegalovirus IE86 protein can block cell cycle progression after inducing transition into the S phase of permissive cells The cyclin E promoter is activated by human cytomegalovirus 86-kDa immediate early protein TFIIB and the regulation of transcription by RNA polymerase II. Interaction of the COOH-terminal transactivation domain of p65 NF-kappa B with TATA-binding protein, transcription factor IIB, and coactivators Functional interaction between the HCMV IE2 transactivator and the retinoblastoma protein. c-Fos-induced activation of a TATA-box-containing promoter involves direct contact with TATA-box-binding protein Human cytomegalovirus with IE-2 (UL122) deleted fails to express early lytic genes DNA-dependent transregulation by IE1 of Autographa californica nuclear polyhedrosis virus: IE1 domains required for transactivation and DNA binding Covalent modification of the transactivator protein IE2-p86 of human cytomegalovirus by conjugation to the ubiquitin-homologous proteins SUMO-1 and hSMT3b Identification of domains within the human cytomegalovirus major immediate-early 86-kilodalton protein and the retinoblastoma protein required for physical and functional interaction with each other. The human cytomegalovirus. Inhibition of cellular DNA synthesis by the human cytomegalovirus IE86 protein is necessary for efficient virus replication Human cytomegalovirus upregulates NF-kappa B activity by transactivating the NF-kappa B p105/p50 and p65 promoters NF-kappaB-mediated activation of the chemokine CCL22 by the product of the human cytomegalovirus gene UL144 escapes regulation by viral IE86. Negative regulation of the adeno-associated virus (AAV) P5 promoter involves both the P5 rep binding site and the consensus ATP-binding motif of the AAV Rep68 protein Protein-protein interactions between human cytomegalovirus IE2-580aa and pUL84 in lytically infected cells Regulation of human cytomegalovirus US3 gene transcription by a cis-repressive sequence The UL84 protein of human cytomegalovirus acts as a transdominant inhibitor of immediate-early-mediated transactivation that is able to prevent viral replication. Functional properties of the human cytomegalovirus IE86 protein required for transcriptional regulation and virus replication The autoregulatory and transactivating functions of the human cytomegalovirus IE86 protein use independent mechanisms for promoter binding The human cytomegalovirus 86-kilodalton major immediate-early protein interacts physically and functionally with histone acetyltransferase P/CAF. The putative zinc finger of the human cytomegalovirus IE2 86-kilodalton protein is dispensable for DNA binding and autorepression, thereby demarcating a concise core domain in the C terminus of the protein Small internal deletions in the human cytomegalovirus IE2 gene result in nonviable recombinant viruses with differential defects in viral gene expression. Evaluation and mapping of the DNA binding and oligomerization domains of the IE2 regulatory protein of human cytomegalovirus using yeast one and two hybrid interaction assays The equine herpesvirus 1 EICP27 protein enhances gene expression via an interaction with TATA box-binding protein The major transcriptional transactivation domain of simian virus 40 large T antigen associates nonconcurrently with multiple components of the transcriptional preinitiation complex Autorepression of the human cytomegalovirus major immediate-early promoter/enhancer at late times of infection is mediated by the recruitment of chromatin remodeling enzymes by IE86 Human cytomegalovirus IE1 and IE2 proteins block apoptosis Effects of human cytomegalovirus major immediate-early proteins in controlling the cell cycle and inhibiting apoptosis: studies with ts13 cells Cytomegalovirus IE2 protein stimulates interleukin 1beta gene transcription via tethering to Spi-1/PU.1. Development of cell lines that provide tightly controlled temporal translation of the human cytomegalovirus IE2 proteins for complementation and functional analyses of growth-impaired and nonviable IE2 mutant viruses Human cytomegalovirus immediate early proteins and cell growth control TAF-like functions of human cytomegalovirus immediate-early proteins Human cytomegalovirus immediate early interaction with host nuclear structures: definition of an immediate transcript environment CCAAT box-dependent activation of the TATA-less human DNA polymerase alpha promoter by the human cytomegalovirus 72-kilodalton major immediate-early protein Human cytomegalovirus 86-kilodalton IE2 protein blocks cell cycle progression in G(1). Transcriptional regulation of the human cytomegalovirus US11 early gene Phosphorylation of the human cytomegalovirus 86-kilodalton immediate-early protein IE2. The human cytomegalovirus IE2 86-kilodalton protein interacts with an early gene promoter via site-specific DNA binding and protein-protein associations Four of eleven loci required for transient complementation of human cytomegalovirus DNA replication cooperate to activate expression of replication genes. CREB and CREB-binding proteins play an important role in the IE2 86-kilodalton protein-mediated transactivation of the human cytomegalovirus 2.2-kilobase RNA promoter. Binding of SP1 to the immediate-early protein-responsive element of the human cytomegalovirus DNA polymerase promoter Transactivation by the human cytomegalovirus IE2 86-kilodalton protein requires a domain that binds to both the TATA box-binding protein and the retinoblastoma protein. Efficient and tightly regulated expression systems for the human cytomegalovirus major transactivator protein IE2p86 in permissive cells The salivary secretome of the tsetse fly Glossina pallidipes (Diptera: Glossinidae) infected by salivary gland hypertrophy virus. CCAAT/enhancer binding protein-alpha amino acid motifs with dual TBP and TFIIB binding ability co-operate to activate transcription in both yeast and mammalian cells Antagonism between members of the CNC-bZIP family and the immediate-early protein IE2 of human cytomegalovirus Absence of IE1 p72 protein function during low-multiplicity infection by human cytomegalovirus results in a broad block to viral delayed-early gene expression

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