About: Initial evaluation of human recombinant interleukin-1 receptor antagonist in the treatment of sepsis syndrome: a randomized, open-label, placebo-controlled multicenter trial

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About: Initial evaluation of human recombinant interleukin-1 receptor antagonist in the treatment of sepsis syndrome: a randomized, open-label, placebo-controlled multicenter trial Goto Sponge NotDistinct Permalink

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scientific article published on 01 January 1994

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в січні 1994 (uk) im Januar 1994 veröffentlichter wissenschaftlicher Artikel (de) artículu científicu espublizáu en xineru de 1994 (ast) artikull shkencor i botuar më 01 janar 1994 (sq) scientific article published on 01 January 1994 (en)
publication date	wds:Q72285461-CDADEF8B-E649-44BA-9F79-7949AC06EB58
publication date	1994-01-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q72285461-FB6F8BA5-381A-41B5-826D-358A950DEDA2
language of work or name	English
author name string	wds:Q72285461-22A6D7F9-CB6B-4585-9B90-505885CA8951 wds:Q72285461-264EF42C-8C58-482C-9AAB-2105CD5D4585 wds:Q72285461-303AB6F2-DCF1-4546-972F-6906F7F096F0 wds:Q72285461-517157C2-284F-4BA4-A18E-A7C84B3C6FB0 wds:Q72285461-67266886-B37C-4A17-977B-835CFA28FBB3 wds:Q72285461-75EF5C8B-67F2-4971-ABA9-B279FEADCF34 wds:Q72285461-A269BB0F-6DA5-47E4-8757-D6F8C8BCA912 wds:Q72285461-AB0516C5-9904-4941-A919-2626671130B1 wds:Q72285461-AECBC449-B0CC-48D2-815D-4B7BA8114D83 wds:Q72285461-F74792C0-2451-4C45-8E00-CD405FC2A7C7
author name string	G Emmanuel R C Bone S M Opal D Ng C J Fisher M A Catalano G J Slotman D C Bloedow J P Pribble IL-1RA Sepsis Syndrome Study Group
rdfs:label	Initial evaluation of human recombinant interleukin-1 receptor antagonist in the treatment of sepsis syndrome: a randomized, open-label, placebo-controlled multicenter trial (en) Initial evaluation of human recombinant interleukin-1 receptor antagonist in the treatment of sepsis syndrome: a randomized, open-label, placebo-controlled multicenter trial (nl) Initial evaluation of human recombinant interleukin-1 receptor antagonist in the treatment of sepsis syndrome: a randomized, open-label, placebo-controlled multicenter trial (sq)
skos:prefLabel	Initial evaluation of human recombinant interleukin-1 receptor antagonist in the treatment of sepsis syndrome: a randomized, open-label, placebo-controlled multicenter trial (en) Initial evaluation of human recombinant interleukin-1 receptor antagonist in the treatment of sepsis syndrome: a randomized, open-label, placebo-controlled multicenter trial (nl) Initial evaluation of human recombinant interleukin-1 receptor antagonist in the treatment of sepsis syndrome: a randomized, open-label, placebo-controlled multicenter trial (sq)
name	Initial evaluation of human recombinant interleukin-1 receptor antagonist in the treatment of sepsis syndrome: a randomized, open-label, placebo-controlled multicenter trial (en) Initial evaluation of human recombinant interleukin-1 receptor antagonist in the treatment of sepsis syndrome: a randomized, open-label, placebo-controlled multicenter trial (nl) Initial evaluation of human recombinant interleukin-1 receptor antagonist in the treatment of sepsis syndrome: a randomized, open-label, placebo-controlled multicenter trial (sq)
title	wds:Q72285461-229F1BBF-CB18-4D3C-BFF0-0E97998A44AB
title	Initial evaluation of human recombinant interleukin-1 receptor antagonist in the treatment of sepsis syndrome: a randomized, open-label, placebo-controlled multicenter trial (en)
page(s)	wds:Q72285461-DC817DA4-9658-48E2-83B9-22BFB6AD5252
page(s)	12-21
instance of	wds:Q72285461-E2B255E1-83E8-42C2-B4C0-5822AE5E329D
instance of	scholarly article
main subject	wds:Q72285461-5C26C552-9BC4-4C8E-BDC0-94CB6E5B68DE wds:Q72285461-AC0A02CB-7441-4963-BC13-71734B513244 wds:Q72285461-D6FA7FE1-BD07-492F-A195-0505D4BC2882
main subject	placebo sepsis multicenter clinical trial
PubMed ID	wds:Q72285461-B4070359-E24A-4C6D-9205-067E6248671E
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/8124953
PubMed ID	8124953
published in	wds:Q72285461-62786201-4E80-460E-A089-1DECC6E86A0F
published in	Critical Care Medicine
issue	wds:Q72285461-C418F248-7A3C-4777-B726-7C4ABB7AC5A9
volume	wds:Q72285461-E8731D34-977E-4ABF-A9AE-DAAB589ABE96
issue	1
volume	22
DOI	wds:Q72285461-61947D96-F9A1-4B4F-BF07-BD673CD64DEA
DOI	http://dx.doi.org/10.1097/00003246-199401000-00008
DOI	10.1097/00003246-199401000-00008
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q72285461
is cites work of	Simvastatin treatment improves survival in a murine model of burn sepsis: Role of interleukin 6 IL-1: discoveries, controversies and future directions Advances in sepsis therapy The Italian SEPSIS study: preliminary results on the incidence and evolution of SIRS, sepsis, severe sepsis and septic shock Animal models of sepsis Distinctive cytokines as biomarkers predicting fatal outcome of severe Staphylococcus aureus bacteremia in mice Cytokine measurements and interpretation of cytokine assays in human disease Sepsis: a roadmap for future research New strategies for combatting sepsis: the magic bullets missed the mark ... but the search continues Targeting interleukin-1 in heart disease Strategies to improve drug development for sepsis Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases Inhibition of IL-1, IL-6, and TNF-alpha in immune-mediated inflammatory diseases Leukocyte-endothelial cell adhesion: avenues for therapeutic intervention The TFPI-2 derived peptide EDC34 improves outcome of gram-negative sepsis. Development of a genomic metric that can be rapidly used to predict clinical outcome in severely injured trauma patients The role of the endothelium in changes in procoagulant activity in sepsis The role of cytokines in the pathogenesis of acute pancreatitis Deferoxamine reduces tissue injury and lethality in LPS-treated mice Myocardial dysfunction in septic shock A randomised phase II study of interleukin-1 receptor antagonist in acute stroke patients Interleukin-1 and neuronal injury ROS-induced ATF3 causes susceptibility to secondary infections during sepsis-associated immunosuppression Insulin-like growth factor-I regulates the liver microenvironment in obese mice and promotes liver metastasis Autoinflammation: the prominent role of IL-1 in monogenic autoinflammatory diseases and implications for common illnesses The pneumococcus: host-organism interactions and their implications for immunotherapy and immunoprophylaxis Immune dysfunction in trauma The balance between IL-1 and IL-1Ra in disease Role of cytokines in sepsis. Surfactant therapy for acute lung injury and acute respiratory distress syndrome Acute respiratory distress syndrome. Potential pharmacologic interventions Interleukin-1 Receptor Blockade Is Associated With Reduced Mortality in Sepsis Patients With Features of Macrophage Activation Syndrome: Reanalysis of a Prior Phase III Trial Clinical review: Myocardial depression in sepsis and septic shock Management of sepsis in neutropenic patients: 2014 updated guidelines from the Infectious Diseases Working Party of the German Society of Hematology and Medical Oncology (AGIHO). Administration of neutralizing antibody against rabbit IL-1 receptor antagonist exacerbates lipopolysaccharide-induced arthritis in rabbits

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