About: Antifolate-resistant Chinese hamster cells. Evidence for dihydrofolate reductase gene amplification among independently derived sublines overproducing different dihydrofolate reductases

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About: Antifolate-resistant Chinese hamster cells. Evidence for dihydrofolate reductase gene amplification among independently derived sublines overproducing different dihydrofolate reductases Goto Sponge NotDistinct Permalink

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scientific article published on 01 July 1980

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в липні 1980 (uk) scientific article published on 01 July 1980 (en) artículu científicu espublizáu en xunetu de 1980 (ast) im Juli 1980 veröffentlichter wissenschaftlicher Artikel (de)
publication date	wds:Q71241994-59650DFC-BF69-4E5F-9B3A-2960242338FB
publication date	1980-07-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q71241994-E0C8943C-5C35-46DA-840D-0DABC62F5996
language of work or name	English
author name string	wds:Q71241994-1C26EA69-88DA-464B-AEC0-280427C9FEBE wds:Q71241994-1F712096-E09D-4662-B424-09C2A499C745 wds:Q71241994-77922D25-630A-4FCD-A755-D88CF41CD89E wds:Q71241994-8A647B1C-348E-4279-92A8-EDBD1616ECF8
author name string	Melera PW Lewis JA Biedler JL Hession C
rdfs:label	Antifolate-resistant Chinese hamster cells. Evidence for dihydrofolate reductase gene amplification among independently derived sublines overproducing different dihydrofolate reductases (en) Antifolate-resistant Chinese hamster cells. Evidence for dihydrofolate reductase gene amplification among independently derived sublines overproducing different dihydrofolate reductases (nl)
skos:prefLabel	Antifolate-resistant Chinese hamster cells. Evidence for dihydrofolate reductase gene amplification among independently derived sublines overproducing different dihydrofolate reductases (en) Antifolate-resistant Chinese hamster cells. Evidence for dihydrofolate reductase gene amplification among independently derived sublines overproducing different dihydrofolate reductases (nl)
name	Antifolate-resistant Chinese hamster cells. Evidence for dihydrofolate reductase gene amplification among independently derived sublines overproducing different dihydrofolate reductases (en) Antifolate-resistant Chinese hamster cells. Evidence for dihydrofolate reductase gene amplification among independently derived sublines overproducing different dihydrofolate reductases (nl)
title	wds:Q71241994-DABCB50A-3C23-4E86-B9B1-45B3BF105554
title	Antifolate-resistant Chinese hamster cells. Evidence for dihydrofolate reductase gene amplification among independently derived sublines overproducing different dihydrofolate reductases (en)
page(s)	wds:Q71241994-80EA151B-3825-4252-8631-BB1B58A21FFC
page(s)	7024-7028
instance of	wds:Q71241994-0C4F9F43-3967-44CD-91B9-1ABA3B6BF8A3
instance of	scholarly article
PubMed ID	wds:Q71241994-2B1A213C-6485-46C7-B3FF-A66F96B934FE
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/7391066
PubMed ID	7391066
published in	wds:Q71241994-0FE13845-368B-4DA1-9E8D-0413318129DB
published in	Journal of Biological Chemistry
issue	wds:Q71241994-64C9531F-3396-4C5C-B362-8971F951D3B7
volume	wds:Q71241994-69A5B4B4-CD84-434E-A12A-C58B45340A26
issue	14
volume	255
number of pages	wds:Q71241994-2D796326-C07C-4341-91DA-C6F733DD0D57
number of pages	5 (xsd:decimal)
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q71241994
is cites work of	Systemic resistance to methotrexate in transgenic mice carrying a mutant dihydrofolate reductase gene Methotrexate-resistant Chinese hamster ovary cells have amplified a 135-kilobase-pair region that includes the dihydrofolate reductase gene. Amplification and loss of dihydrofolate reductase genes in a Chinese hamster ovary cell line Determinants of the sensitivity of human small-cell lung cancer cell lines to methotrexate Coordinate amplification of metallothionein I and II genes in cadmium-resistant Chinese hamster cells: implications for mechanisms regulating metallothionein gene expression Enhancement of methotrexate resistance and dihydrofolate reductase gene amplification by treatment of mouse 3T6 cells with hydroxyurea Activation mechanism and modification kinetics of Chinese hamster dihydrofolate reductase by p-chloromercuribenzoate Phenotypic Expression in Escherichia coli and Nucleotide Sequence of Two Chinese Hamster Lung Cell cDNAs Encoding Different Dihydrofolate Reductases Control of cellular gene expression during adenovirus infection: induction and shut-off of dihydrofolate reductase gene expression by adenovirus type 2 Nucleotide sequence of dihydrofolate reductase genes from trimethoprim-resistant mutants of Escherichia coli. Evidence that dihydrofolate reductase interacts with another essential gene product. Evolution of chromosomal regions containing transfected and amplified dihydrofolate reductase sequences Variable content of double minute chromosomes is not correlated with degree of phenotype instability in methotrexate-resistant human cell lines Gene amplification accompanies low level increases in the activity of dihydrofolate reductase in antifolate-resistant Chinese hamster lung cells containing abnormally banding chromosomes Gene amplification-associated cytogenetic aberrations and protein changes in vincristine-resistant Chinese hamster, mouse, and human cells Specific DNA sequence amplification in human neuroblastoma cells Homologous sequences other than insertion elements can serve as recombination sites in plasmid drug resistance gene amplification Gene amplification in methotrexate-resistant mouse cells. IV. Different DNA sequences are amplified in different resistant lines Molecular cloning of Chinese hamster dihydrofolate reductase-specific cDNA and the identification of multiple dihydrofolate reductase mRNAs in antifolate-resistant Chinese hamster lung fibroblasts Differential utilization of poly (A) signals between DHFR alleles in CHL cells Selective amplification of polymorphic dihydrofolate reductase gene loci in Chinese hamster lung cells UV radiation facilitates methotrexate resistance and amplification of the dihydrofolate reductase gene in cultured 3T6 mouse cells Double minutes, cytogenetic equivalents of gene amplification, in human neoplasia - a review Resistance to cytostatic drugs at the cellular level Overproduction of Dihydrofolate Reductase and Gene Amplification in Methotrexate-Resistant Chinese Hamster Ovary Cells Regular pattern of karyotypic alterations accompanying gene amplification in Djungarian hamster cells: study of colchicine, adriablastin, and methotrexate resistance. Altered expression after expansion of a v-erbA transgene in transgenic mice Increased dihydrofolate reductase activity in methotrexate-resistant human promyelocytic-leukaemia (HL-60) cells. Lack of correlation between increased activity and overproduction Correlation of unstable multidrug cross resistance in Chinese hamster ovary cells with a homogeneously staining region on chromosome 1. Inactivation kinetics of dihydrofolate reductase from Chinese hamster during urea denaturation Isolation and characterization of a dihydrofolate reductase gene mutation in methotrexate-resistant Drosophila cells.
is cites work of	wds:Q36211582-4E8D38E3-5743-4FF3-A9F8-49A2F9DA38B9 wds:Q35938476-C7D54085-0BD8-4B9D-BF62-B655D5924EED wds:Q52829658-1A890595-269E-48D8-A354-3AE67F11C688 wds:Q36596953-93415DA5-D7E9-4863-9879-5C3DD3858CC1 wds:Q48406480-DB55242D-017D-475B-B206-7BA9FFB4DD37 wds:Q36969741-1AB3A6DE-526C-4B94-8882-6CF253A0B4C7 wds:Q36025616-8EFDB410-1E5B-4F85-9E8D-6409E50769EE wds:Q34557626-CC95F38C-F273-448B-ABEE-007BBFAE3A06 wds:Q36945057-18F3472A-4045-496A-ACF1-B043A12AD777 wds:Q42986660-7E0521C8-7D64-4816-81B4-A65025678F71 wds:Q42848953-12A08555-4018-4488-8BF8-47FFDC76DBF9 wds:Q42991787-149AD28A-28B4-484F-A766-747E6740D61A wds:Q24605671-580470AF-EF3A-4A5B-AC3E-9C9A01D66F7C wds:Q36938379-48EC8566-03D1-4F63-9121-BD013449C402 wds:Q37349626-211BE030-C4FB-4617-9DD8-ED1F465FA292 wds:Q36978527-0064468D-B0DA-4ED7-B0E7-BF6207FF8963 wds:Q36293654-FCD98736-5657-4855-8552-2364D3A6DC93 wds:Q36350678-1A5C0DDD-7CC1-4918-B07E-C6879E71F0CE wds:Q37411968-14D83CE2-4238-4196-9FA4-7B72BC13EB6A wds:Q43913315-B7876001-C5FE-4A91-93ED-A9FFA17D23E5 wds:Q36939864-3A9F37BF-62BC-420D-8F10-4591DFDB3CEB wds:Q41241974-C92A1881-EC05-4224-A9D3-FD3907A5D28C wds:Q36209100-BB6213A6-567C-4D76-9A4B-1306B22426DF wds:Q36885489-5C41B8F4-2182-435C-B7F8-E44D001E1A45 wds:Q36321128-339FF9F0-E5FB-4FDC-B732-5D9E06639568 wds:Q35703560-88C6299A-31E2-47A1-B1D8-421C4D111EC0 wds:Q36938706-FE65CEF7-971E-458D-88FD-03682FE06007 wds:Q30450050-87F11F22-3A38-4AAC-B435-55E3A1B4085A

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