About: Intestinal absorption barriers and transport mechanisms, including secretory transport, for a cyclic peptide, fibrinogen antagonist

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scientific article published on 01 January 1996

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) articolo scientifico (pubblicato il 1996) (it) наукова стаття, опублікована в січні 1996 (uk) im Januar 1996 veröffentlichter wissenschaftlicher Artikel (de) artículu científicu espublizáu en xineru de 1996 (ast) artikull shkencor i botuar më 01 janar 1996 (sq) scientific article published on 01 January 1996 (en)
publication date	wds:Q71156179-1A288260-CCC3-4AF8-8C00-16F82CDDB79D
publication date	1996-01-01 00:00:00Z (xsd:dateTime)
cites work	wds:Q71156179-163BC3DD-F5A5-432D-9EB7-5E3D2F12FAB1 wds:Q71156179-440807A7-B174-4A79-8262-737D6B8F5FD6 wds:Q71156179-656F5215-9B97-4B6F-89D4-30F64999AE08 wds:Q71156179-7439A1BC-ACD1-4ABB-BAD9-6C3C1536D05A wds:Q71156179-7A650CEF-588C-481F-9513-10371A9D205F wds:Q71156179-8D8FD4C2-5EBC-4D7B-A14F-AAE0123FF573 wds:Q71156179-9A8239CD-B913-436B-8D69-AEB44DB0000A wds:Q71156179-9E7055CE-30FE-45EC-803B-D1C19551EB99 wds:Q71156179-A432309C-0D66-45E7-A5FE-957EFE7EDF5C wds:Q71156179-B56CF3B2-218C-4BD3-AFC7-3BAA2F92B080 wds:Q71156179-C7C9FB72-5F5E-4B41-A386-5296721B52AE wds:Q71156179-CFD3088C-A1C9-43F7-82DA-21A0F92A694B wds:Q71156179-D7A054E1-A382-4E69-8A05-2F4E35C1F1D6 wds:Q71156179-E42FB370-4220-4252-88C1-81E5E8AFB434 wds:Q71156179-ECBBA459-2DD8-44D4-8D6F-9FCBBAB3DDB3 wds:Q71156179-EDA6459F-85EF-4404-AE98-01DA3144B0DB
cites work	Drug absorption limited by P-glycoprotein-mediated secretory drug transport in human intestinal epithelial Caco-2 cell layers Uncoupling of the molecular 'fence' and paracellular 'gate' functions in epithelial tight junctions Functional expression of P-glycoprotein in apical membranes of human intestinal Caco-2 cells. Kinetics of vinblastine secretion and interaction with modulators Transcellular transport of oral cephalosporins in human intestinal epithelial cells, Caco-2: interaction with dipeptide transport systems in apical and basolateral membranes. Transport of guanidine in rabbit intestinal brush-border membrane vesicles Evidence for a polarized efflux system in CACO-2 cells capable of modulating cyclosporin A transport In vitro measurement of gastrointestinal tissue permeability using a new diffusion cell. The function of Gp170, the multidrug-resistance gene product, in the brush border of rat intestinal mucosa Evidence for a polarized efflux system for peptides in the apical membrane of Caco-2 cells Measurements of intestinal permeability using low molecular weight polyethylene glycols (PEG 400). II. Application to normal and abnormal permeability states in man and animals Possible involvement of multiple P-glycoprotein-mediated efflux systems in the transport of verapamil and other organic cations across rat intestine Kinetic evidence suggesting that the multidrug transporter differentially handles influx and efflux of its substrates. Development of GPIIb/IIIa antagonists as antithrombotic drugs Antiplatelet and antithrombotic efficacy of DMP 728, a novel platelet GPIIb/IIIa receptor antagonist Mechanism and site dependency of intestinal mucosal transport and metabolism of thymidine analogues An in vitro evaluation of metabolism and poor membrane permeation impeding intestinal absorption of leucine enkephalin, and methods to increase absorption
author name string	wds:Q71156179-5889AF23-CF0E-4CC3-975F-198DFEA0192E wds:Q71156179-84D4A0FE-5115-4678-A050-DDCB863973B8
author name string	H Saitoh B J Aungst
rdfs:label	Intestinal absorption barriers and transport mechanisms, including secretory transport, for a cyclic peptide, fibrinogen antagonist (en) Intestinal absorption barriers and transport mechanisms, including secretory transport, for a cyclic peptide, fibrinogen antagonist (nl) Intestinal absorption barriers and transport mechanisms, including secretory transport, for a cyclic peptide, fibrinogen antagonist (sq)
skos:prefLabel	Intestinal absorption barriers and transport mechanisms, including secretory transport, for a cyclic peptide, fibrinogen antagonist (en) Intestinal absorption barriers and transport mechanisms, including secretory transport, for a cyclic peptide, fibrinogen antagonist (nl) Intestinal absorption barriers and transport mechanisms, including secretory transport, for a cyclic peptide, fibrinogen antagonist (sq)
name	Intestinal absorption barriers and transport mechanisms, including secretory transport, for a cyclic peptide, fibrinogen antagonist (en) Intestinal absorption barriers and transport mechanisms, including secretory transport, for a cyclic peptide, fibrinogen antagonist (nl) Intestinal absorption barriers and transport mechanisms, including secretory transport, for a cyclic peptide, fibrinogen antagonist (sq)
title	wds:Q71156179-A6D5CE3D-FE6F-4F4B-8567-DBA90E4C1E98
title	Intestinal absorption barriers and transport mechanisms, including secretory transport, for a cyclic peptide, fibrinogen antagonist (en)
page(s)	wds:Q71156179-E41CCB12-EF05-4369-ABAA-0AF21DD5717D
page(s)	114-119
instance of	wds:Q71156179-B5C70C5D-4E55-4D83-8304-ACA5B2EF4236
instance of	scholarly article
PubMed ID	wds:Q71156179-8E6FAA77-4099-4C9F-B2AC-049F5EBAAB24
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/8668658
PubMed ID	8668658
published in	wds:Q71156179-FE44A28A-869A-497A-B84F-E0B668660F38
published in	Pharmaceutical Research
issue	wds:Q71156179-6BDB5288-4267-40F7-8AED-FE8C1AF87EDD
volume	wds:Q71156179-141D57C2-B14C-404B-BC34-B0BC8CBB921C
issue	1
volume	13
DOI	wds:Q71156179-A2B378A4-A544-4D2B-BD84-C1DC9E206475
DOI	http://dx.doi.org/10.1023/A:1016093704095
DOI	10.1023/A:1016093704095
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q71156179
is cites work of	Contribution of the murine mdr1a P-glycoprotein to hepatobiliary and intestinal elimination of cationic drugs as measured in mice with an mdr1a gene disruption. Involvement of intestinal P-glycoprotein in the restricted absorption of methylprednisolone from rat small intestine Restricted intestinal absorption of some beta-lactam antibiotics by an energy-dependent efflux system in rat intestine Enhanced intestinal absorption of vancomycin with Labrasol and D-alpha-tocopheryl PEG 1000 succinate in rats Virtual screening of intestinal drug permeability Calcein is excreted from the intestinal mucosal cell membrane by the active transport system Drug exsorption from blood into the gastrointestinal tract Prodrug and analog approaches to improving the intestinal absorption of a cyclic peptide, GPIIb/IIIa receptor antagonist Prodrug approach for alphaIIbbeta3-peptidomimetic antagonists to enhance their transport in monolayers of a human intestinal cell line (Caco-2): comparison of in vitro and in vivo data Improvement of the intestinal absorption of a peptidomimetic, boronic acid thrombin inhibitor possibly utilizing the oligopeptide transporter Transport of peptidomimetic thrombin inhibitors with a 3-amidino-phenylalanine structure: permeability and efflux mechanism in monolayers of a human intestinal cell line (Caco-2). Arbekacin is actively secreted in the rat intestine via a different efflux system from P-glycoprotein
is cites work of	wds:Q30583910-DEA823DB-6592-4690-9054-F9FC69E9648B wds:Q73654392-9EA967CA-1592-4CA4-8CB2-62371971B095 wds:Q73203997-C7F243F9-ECAE-4A1F-9BC5-30D51B5EBC02 wds:Q33852942-82485036-7FA4-445E-8635-5401997CEF13 wds:Q41751961-A0CBCAAD-BD0E-4FEE-8DCD-23C4BC12EC4E wds:Q40776707-56A88ED7-898E-4EA8-A4B0-1BDBE8EC5275 wds:Q40641898-0EDED8FC-37D8-49D3-842A-D6D2FCDE517D wds:Q74130503-0CAA446D-7453-4CFD-A393-7ED12A3CC018 wds:Q73017519-76CD22C1-0667-44F9-A9F6-DAF73291B873 wds:Q44247758-F262A542-0CF1-4AF4-AAB5-9E16464C9B77 wds:Q52530011-2253562A-3A8F-4758-882C-A9B4C1A1F27A wds:Q73371179-68932DFD-40AD-4CB4-92D2-9D9F0FC06753

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