About: genes, MHC class I

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genetic loci in the vertebrate major histocompatibility complex which encode polymorphic characteristics not related to immune responsiveness or complement activity,

Attributes	Values
rdf:type	Item
description	genetic loci in the vertebrate major histocompatibility complex which encode polymorphic characteristics not related to immune responsiveness or complement activity, (en)
rdfs:label	genes, MHC class I (en)
skos:prefLabel	genes, MHC class I (en)
name	genes, MHC class I (en)
facet of	wds:Q70695240-1509637f-407b-c1ea-7ebb-7253df9b7382
facet of	major histocompatibility complex
skos:altLabel	MHC Class I gene (en) MHC Class I genes (en)
MeSH descriptor ID	wds:Q70695240-0A8D2951-9563-41A3-8F87-F80BFF410B66
MeSH tree code	wds:Q70695240-0490834f-4f63-f1ca-0af0-70a3f941ca7d wds:Q70695240-5a21bca3-4dcd-05ce-348d-4a0823e8a953 wds:Q70695240-e580f32b-45a8-181a-ef65-4c70768df75d
MeSH descriptor ID	http://id.nlm.nih.gov/mesh/D005805
MeSH tree code	http://id.nlm.nih.gov/mesh/G05.360.340.024.340.610.595 http://id.nlm.nih.gov/mesh/G05.360.340.024.380.500.595 http://id.nlm.nih.gov/mesh/G12.500.500.595
MeSH descriptor ID	D005805
MeSH tree code	G05.360.340.024.340.610.595 G05.360.340.024.380.500.595 G12.500.500.595
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q70695240
is main subject of	Molecular cloning of orangutan and gibbon MHC class I cDNA. The HLA-A and -B loci diverged over 30 million years ago H-2 haplotype and sex-related differences in IgG response to ovalbumin in mice HLA alleles in isolated populations from North Spain: Origin of the Basques and the ancient Iberians Alloantigen recognition by two human natural killer cell clones is associated with HLA-C or a closely linked gene DNA recombination and natural selection pressure sustain genetic sequence diversity of the feline MHC class I genes Co-duplication of olfactory receptor and MHC class I genes in the mouse major histocompatibility complex Structure and expression of major histocompatibility complex-binding protein 2, a 275-kDa zinc finger protein that binds to an enhancer of major histocompatibility complex class I genes Regulation of the mouse alpha A-crystallin gene: isolation of a cDNA encoding a protein that binds to a cis sequence motif shared with the major histocompatibility complex class I gene and other genes Linkage of Faulty Major Histocompatibility Complex Class I to Autoimmune Diabetes Human leukocyte antigen F (HLA-F). An expressed HLA gene composed of a class I coding sequence linked to a novel transcribed repetitive element The regulation and expression of MHC class I genes Beta 2 microglobulin on the envelope of urinary cytomegalovirus is not associated with host class I human leukocyte antigen alpha chain The HLA class I gene family includes at least six genes and twelve pseudogenes and gene fragments Examination of four HLA class I pseudogenes. Common events in the evolution of HLA genes and pseudogenes c-myc down-regulates class I HLA expression in human melanomas Alternative splicing of HLA-G transcripts yields proteins with primary structures resembling both class I and class II antigens Precise prediction of a dominant class I MHC-restricted epitope of Listeria monocytogenes Down-regulation of the major histocompatibility complex class I enhancer in adenovirus type 12-transformed cells is accompanied by an increase in factor binding Gorilla class I major histocompatibility complex alleles: comparison to human and chimpanzee class I Effects of MHC Class I on HIV/SIV Disease in Primates Involvement of HLA class I alleles in natural killer (NK) cell-specific functions: expression of HLA-Cw3 confers selective protection from lysis by alloreactive NK clones displaying a defined specificity (specificity 2) How the virus outsmarts the host: function and structure of cytomegalovirus MHC-I-like molecules in the evasion of natural killer cell surveillance DNA typing for HLA class I alleles: I. Subsets of HLA-A2 and of -A28 Identification of a shark sequence resembling the major histocompatibility complex class I alpha 3 domain Evolution of the major histocompatibility complex: a hundred-fold amplification of MHC class I genes in the African pigmy mouse Nannomys setulosus Physical and genetic mapping of the rainbow trout major histocompatibility regions: evidence for duplication of the class I region Idiopathic childhood stroke is associated with human leukocyte antigen (HLA)-B51 Understanding how combinations of HLA and KIR genes influence disease Qa-region class I gene expression: identification of a second class I gene, Q9, encoding a Qa-2 polypeptide Gene conversion in the evolution of the human and chimpanzee MHC class I loci Infection by polyomavirus of murine cells deficient in class I major histocompatibility complex expression Selection, hitchhiking and disequilibrium analysis at three linked loci with application to HLA data Local T cell responses induce widespread MHC expression. Evidence that IFN-gamma induces its own expression in remote sites Occupancy of upstream regulatory sites in vivo coincides with major histocompatibility complex class I gene expression in mouse tissues Genomic organization and sequence of a rat class I MHC gene that is an apparent pseudogene Identification of Regulatory Elements Associated with a Class I MHC Gene Genetic control of nonresponsiveness to hepatitis B virus vaccine by an extended HLA haplotype The B4002 allele encodes the B61 antigen: B40 is identical to B61 A polymorphic HLA-DPA-like locus, unlinked to the rat major histocompatibility complex Changes in NF-kappa B and ISGF3 DNA binding activities are responsible for differences in MHC and beta-IFN gene expression in Ad5- versus Ad12-transformed cells Negative regulation of the major histocompatibility complex class I enhancer in adenovirus type 12-transformed cells via a retinoic acid response element Reduced binding activity of transcription factor NF-kappa B accounts for MHC class I repression in adenovirus type 12 E 1-transformed cells Peripheral tolerance of an allograft in adult rats--characterization by low interleukin-2 and interferon-gamma mRNA levels and by strong accumulation of major histocompatibility complex transcripts in the graft Retroviral Transfer of Donor MHC Class I or MHC Class II Genes into Recipient Bone Marrow Cells Can Induce Operational Tolerance to AlloantigensIn Vivo Rejection of B16 melanoma induced by expression of a transfected major histocompatibility complex class I gene Retinoic acid-dependent transactivation of major histocompatibility complex class I promoters by the nuclear hormone receptor H-2RIIBP in undifferentiated embryonal carcinoma cells Hormonal regulation of major histocompatibility complex class I genes in rat thyroid FRTL-5 cells: thyroid-stimulating hormone induces a cAMP-mediated decrease in class I expression Locus-specific transcriptional control of HLA genes Tolerance and MHC restriction in transgenic mice expressing a MHC class I gene in erythroid cells Evidence for the expression of non-HLA-A,-B,-C class I genes in the human fetal liver Nomenclature for factors of the HLA system, 1991. The WHO Nomenclature Committee for factors of the HLA system Altered binding of regulatory factors to HLA class I enhancer sequence in human tumor cell lines lacking class I antigen expression Heterozygosity of the major histocompatibility complex controls the autoimmune disease in (NZW x BXSB) F1 mice Of volatiles and peptides: in search for MHC-dependent olfactory signals in social communication Structural diversity of the classical H-2 genes: K, D, and L Association of HLA phenotype with response to active specific immunotherapy of melanoma The role of MHC class I gene products in SIV infection of macaques Cloning and expression of class I major histocompatibility complex genes of the rat Mammalian CD1 and MR1 genes No independent association between HSP70 gene polymorphism and IDDM Detection of hereditary haemochromatosis in an HLA-identical pedigree showing discordance between HLA class I genes and the disease locus Association of HLA-B51 and lack of association of class II alleles with Behçet's disease Class I gene contraction within the HLA-A subregion of the human MHC The human class I MHC gene HLA-F is expressed in lymphocytes The human cDNA sequence homologous to the mouse MHC class I promoter-binding protein gene contains four additional codons in lymphocytes Effect of epidermal growth factor in HLA class I and class II transcription and protein expression in human breast adenocarcinoma cell lines HLA Antigens in Insulin-Dependent Diabetes Mellitus Spontaneous recovery from Friend retrovirus-induced leukemia. Mapping of the Rfv-2 gene in the Q/TL region of mouse MHC Mapping of the rabbit MHC reveals that class I genes are adjacent to the DR subregion and defines an insertion/deletion-related polymorphism in the class II region Molecular mediators and events associated with attenuated MHC class I gene expression The role of adenovirus oncogenes in down-regulation of major histocompatibility class I gene expression Purification and ligand binding of a soluble class I major histocompatibility complex molecule consisting of the first three domains of H-2Kd fused to beta 2-microglobulin expressed in the baculovirus-insect cell system Mixed lymphocyte culture studies reveal complexity in the bovine MHC not detected by class I serology Limited MHC class I polymorphism is not essential for bone marrow chimerism in New World primates Differential expression of isoproterenol‐induced salivary polypeptides in two mouse strains that are congenic for the H‐2 histocompatibility gene complex Polymorphism of HLA in the Romanian population HLA-A region in highly sensitized patients: another immune response gene region Different regulation of class I gene expression in the adult mouse and during development

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