About: Pharmacokinetics of dacarbazine (DTIC) and its metabolite 5-aminoimidazole-4-carboxamide (AIC) following different dose schedules

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About: Pharmacokinetics of dacarbazine (DTIC) and its metabolite 5-aminoimidazole-4-carboxamide (AIC) following different dose schedules Goto Sponge NotDistinct Permalink

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scientific article published on 01 January 1982

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) articolo scientifico (pubblicato il 1982) (it) наукова стаття, опублікована в січні 1982 (uk) im Januar 1982 veröffentlichter wissenschaftlicher Artikel (de) artikull shkencor i botuar më 01 janar 1982 (sq) scientific article published on 01 January 1982 (en) artículu científicu espublizáu en xineru de 1982 (ast)
publication date	wds:Q70596840-30F20B31-F361-410B-ABFD-B87DF80F32BC
publication date	1982-01-01 00:00:00Z (xsd:dateTime)
exact match	wds:Q70596840-419CE81B-3C94-4CE8-A987-AA0D6EB9B5D7
exact match	https://scigraph.springernature.com/pub.10.1007/bf00265388
cites work	wds:Q70596840-169C4CD4-B955-43B2-B1E0-7F1F61BFD085 wds:Q70596840-27F55F39-9DC8-4D0E-ACAE-DCC857EFA0B0 wds:Q70596840-3ED2CCC7-C0CA-406B-9C77-E3D37F4A36FA wds:Q70596840-45C35656-3F9D-45B3-9DFC-449094E10E3B wds:Q70596840-465CCC09-F3A2-46FE-B5FB-AED698F2A8B5 wds:Q70596840-4C743011-952E-4EBB-900C-5DC9AD732E69 wds:Q70596840-55B959CE-BEF8-449C-B728-0C1101B41E8C wds:Q70596840-5F37F1F5-770E-4635-9457-ACE0D0987AA7 wds:Q70596840-694B4766-0483-4D25-A48E-5DC7A2F3FB8B wds:Q70596840-6A89C56B-A942-4670-AEDB-071C189638E2 wds:Q70596840-6F5AF081-CBF0-4785-AE95-599195604438 wds:Q70596840-798038EF-0C33-4D81-883D-BB0DE8E1911B wds:Q70596840-7A6EDDC6-B61C-445F-A3E5-6405B51CE548 wds:Q70596840-87149EAC-2E58-4174-A318-2E843E6FC8FA wds:Q70596840-87934571-5F66-4594-9CBF-4742D82AD533 wds:Q70596840-A3ADA019-85AB-4330-81B0-21F1C6F96F0F wds:Q70596840-A7C70FB7-8D51-46A5-BAB3-65BAF54598C7 wds:Q70596840-ADED81C5-52BD-4A26-8627-778BBAF57BCE wds:Q70596840-B32511FE-AB39-4505-904A-E0B0374A642F wds:Q70596840-BCD8CFCE-61E4-45E9-A300-F4C5DD13D1F1 wds:Q70596840-CC4F613C-E123-4596-80E0-8568C6E0666B wds:Q70596840-CC5343D1-81DD-4BCF-9F62-89251BA87AB6 wds:Q70596840-CDD0A54C-76FC-4402-BE1A-926956F557E8 wds:Q70596840-D31BE6F4-A420-4778-A615-198680D1BDC2 wds:Q70596840-D4DE7CB8-4250-4677-8164-7448D163C946 wds:Q70596840-D963F8BE-9D2C-4102-8B2D-16BDDB004386 wds:Q70596840-E93D369F-00B5-40F6-9017-68E2C447F38E wds:Q70596840-F627D877-13D8-4D3C-A577-F74F8DA8EB04 wds:Q70596840-F73D4C04-E70C-44F8-B6A9-0B50EC93750B
cites work	DTIC (NSC-45388) in malignant melanoma: a perspective Inhibition of drug-metabolizing enzymes in the rat after Bacillus Calmette-Guérin treatment Characteristics of prognosis and response to an imidazole carboxamide in malignant melanoma Mechanism of action and pharmacology studies with DTIC (NSC-45388) DTIC therapy in metastatic malignant melanoma: a simplified dose schedule Recent trends in the medical treatment of Hodgkin's disease Method for detection of 2-azahypoxanthine in human and rat urine Preliminary clinical trial and the physiologic disposition of 4(5)-(3,3-dimethyl-1-triazeno)imidazole-5(4)-carboxamide in man Disposition of 5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide, a new antitumor agent The pharmacokinetic basis of optimal antibiotic dosage. Cyclophosphamide, vincristine, adriamycin, and DTIC (CYVADIC) combination chemotherapy for the treatment of advanced sarcomas. Intra-arterial therapy of melanoma with dimethyl triazeno imidazole carboxamide (NSC-45388) Mechanism of action of 5-(3,3-dimethyl-1-triazeno)imidazole-4-caboxamide in mammalian cells in culture Methylation of nucleic acids and urinary excretion of 14 C-labeled 7-methylguanine by rats and man after administration of 4(5)-(3,3-dimethyl-1-triazeno)-imidazole5(4)-carboxomide. Pharmacologic studies of the antitumor agent 5-(dimethyltriazeno)imidazole-4-carboxamide Intermittent treatment of metastatic malignant melanoma with high-dose 5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide (NSC-45388) Colorimetric determination of dialkyltriazenoimidazoles Elevated urinary excretion of 4-aminoimidazole-5-carboxamide in patients after intravenous injection of 4-(3, 3-dimethyl-1-triazeno) imidazole-5-carboxamide Role of DTIC (NSC-45388) in the chemotherapy of sarcomas Regional chemotherapy of maxillofacial malignant melanoma with intracarotid artery infusion of DTIC N-demethylation the antineoplastic agent4(5)-(3,3-dimethyl-1-triazeno)imidazole-5(4)-carboxamide by rats and man Phase I--II study of intermittent bolus administration of DTIC and actinomycin D in metastatic malignant melanoma Effects of intravenous and intracutaneous bacillus Calmette-Guérin application on the drug-metabolizing system of the liver Intra-arterial infusion therapy with 5-(3,3-dimeth yl-1-triazeno) imidazole-4-carboxamide (NSC 45388) for malignant melanoma Microsomal metabolism of triazenylimidazoles Stochastic compartmental modeling of the disposition of 5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide (NSC-45388) Experimental studies at Southern Research Institute with DTIC (NSC-45388) Fate of the ring moiety of 5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide in mammalian cells Metabolism of 5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide (NSC-45388) in human and animal tumor tissue
author name string	wds:Q70596840-47077C03-CFE1-4BA5-B829-3FDCF8B81232 wds:Q70596840-6549E50A-F2B9-4380-9E14-1A6448F21684 wds:Q70596840-9041F798-1A8A-4819-98C9-DC6FF8AC3217
author name string	K Aigner H Breithaupt A Dammann
rdfs:label	Pharmacokinetics of dacarbazine (DTIC) and its metabolite 5-aminoimidazole-4-carboxamide (AIC) following different dose schedules (en) Pharmacokinetics of dacarbazine (DTIC) and its metabolite 5-aminoimidazole-4-carboxamide (AIC) following different dose schedules (nl) Pharmacokinetics of dacarbazine (DTIC) and its metabolite 5-aminoimidazole-4-carboxamide (AIC) following different dose schedules (sq)
skos:prefLabel	Pharmacokinetics of dacarbazine (DTIC) and its metabolite 5-aminoimidazole-4-carboxamide (AIC) following different dose schedules (en) Pharmacokinetics of dacarbazine (DTIC) and its metabolite 5-aminoimidazole-4-carboxamide (AIC) following different dose schedules (nl) Pharmacokinetics of dacarbazine (DTIC) and its metabolite 5-aminoimidazole-4-carboxamide (AIC) following different dose schedules (sq)
name	Pharmacokinetics of dacarbazine (DTIC) and its metabolite 5-aminoimidazole-4-carboxamide (AIC) following different dose schedules (en) Pharmacokinetics of dacarbazine (DTIC) and its metabolite 5-aminoimidazole-4-carboxamide (AIC) following different dose schedules (nl) Pharmacokinetics of dacarbazine (DTIC) and its metabolite 5-aminoimidazole-4-carboxamide (AIC) following different dose schedules (sq)
title	wds:Q70596840-95C6DF94-8090-4FC7-AB33-F503E32B39D2
title	Pharmacokinetics of dacarbazine (DTIC) and its metabolite 5-aminoimidazole-4-carboxamide (AIC) following different dose schedules (en)
page(s)	wds:Q70596840-7A5E3A9F-3B26-4E54-83FA-5531B42EBCEF
page(s)	103-109
instance of	wds:Q70596840-68CE4AC3-041A-40C8-AA6F-F8E9CEDB5AD7
instance of	scholarly article
main subject	wds:Q70596840-6D5F8AE9-0877-4E89-A388-D4A68B438079 wds:Q70596840-96869128-A6B4-41A5-B845-5410E5E6C386
main subject	dacarbazine pharmacokinetics
PubMed ID	wds:Q70596840-315976E7-40D4-4ED6-B05B-F35B38F801FF
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/7172404
PubMed ID	7172404
published in	wds:Q70596840-B29D59BA-AC72-4A5F-9C5D-0378BD7D19B8
published in	Cancer Chemotherapy and Pharmacology

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