About: Enhanced melphalan cytotoxicity in human ovarian cancer in vitro and in tumor-bearing nude mice by buthionine sulfoximine depletion of glutathione

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About: Enhanced melphalan cytotoxicity in human ovarian cancer in vitro and in tumor-bearing nude mice by buthionine sulfoximine depletion of glutathione Goto Sponge NotDistinct Permalink

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scientific article published on 01 January 1987

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в січні 1987 (uk) im Januar 1987 veröffentlichter wissenschaftlicher Artikel (de) artículu científicu espublizáu en xineru de 1987 (ast) artikull shkencor i botuar më 01 janar 1987 (sq) scientific article published on 01 January 1987 (en)
publication date	wds:Q69714317-02E971C7-B71B-4777-AC36-B39FC4FA23B5
publication date	1987-01-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q69714317-F126DFCC-F6FC-4CCA-A724-AB52DA74378C
language of work or name	English
cites work	wds:Q69714317-7AA4650B-DAE8-4BAA-8FF3-C6F1F4F1A383
cites work	Reactivity of a monoclonal antibody with human ovarian carcinoma
author name string	wds:Q69714317-29E9F358-D6CC-4892-8DA5-9132C7722B8D wds:Q69714317-35421FF5-013C-45EA-9C43-E21F5FA50C40 wds:Q69714317-44CF86FE-3F2C-4E04-AD34-425008CC01BF wds:Q69714317-63DA8F40-F492-4439-BB64-B55BE7E64907 wds:Q69714317-B9ADDFCD-6D55-40B5-83A4-1CBB65F7A8A1 wds:Q69714317-E2DD5939-CF4E-4F92-9E89-A613C6888FA0 wds:Q69714317-FE5CCCF8-A124-4ED7-B059-E31E96570F66
author name string	R L Fine T C Hamilton R F Ozols B C Behrens J Plowman K G Louie D Dykes
rdfs:label	Enhanced melphalan cytotoxicity in human ovarian cancer in vitro and in tumor-bearing nude mice by buthionine sulfoximine depletion of glutathione (en) Enhanced melphalan cytotoxicity in human ovarian cancer in vitro and in tumor-bearing nude mice by buthionine sulfoximine depletion of glutathione (nl) Enhanced melphalan cytotoxicity in human ovarian cancer in vitro and in tumor-bearing nude mice by buthionine sulfoximine depletion of glutathione (sq)
skos:prefLabel	Enhanced melphalan cytotoxicity in human ovarian cancer in vitro and in tumor-bearing nude mice by buthionine sulfoximine depletion of glutathione (en) Enhanced melphalan cytotoxicity in human ovarian cancer in vitro and in tumor-bearing nude mice by buthionine sulfoximine depletion of glutathione (nl) Enhanced melphalan cytotoxicity in human ovarian cancer in vitro and in tumor-bearing nude mice by buthionine sulfoximine depletion of glutathione (sq)
name	Enhanced melphalan cytotoxicity in human ovarian cancer in vitro and in tumor-bearing nude mice by buthionine sulfoximine depletion of glutathione (en) Enhanced melphalan cytotoxicity in human ovarian cancer in vitro and in tumor-bearing nude mice by buthionine sulfoximine depletion of glutathione (nl) Enhanced melphalan cytotoxicity in human ovarian cancer in vitro and in tumor-bearing nude mice by buthionine sulfoximine depletion of glutathione (sq)
title	wds:Q69714317-C3F613DA-CF4F-4ACF-847E-AEE1CE1ABE57
title	Enhanced melphalan cytotoxicity in human ovarian cancer in vitro and in tumor-bearing nude mice by buthionine sulfoximine depletion of glutathione (en)
page(s)	wds:Q69714317-8F040FD5-FC33-436D-8DBD-B2AB4F8703C5
page(s)	147-153
instance of	wds:Q69714317-23A01D19-9B65-41D0-B054-3300C71125C9
instance of	scholarly article
main subject	wds:Q69714317-48B7BFAB-77B0-450A-BE68-629A880C3D56 wds:Q69714317-BDF6A258-FCB6-41DB-9EE1-9C32FCF153A0 wds:Q69714317-C2FEAD91-786E-4143-A8B2-B2DD605307CE
main subject	ovarian neoplasm cytotoxicity glutathione
PubMed ID	wds:Q69714317-9445646E-CCEA-4C84-84B6-981F956D6005
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/3801051
PubMed ID	3801051
published in	wds:Q69714317-34F976C5-0859-4FD4-B1E6-9A8B32C67963
published in	Biochemical Pharmacology
issue	wds:Q69714317-E0CBBE02-DFBE-4C36-8899-71B37301EF50
volume	wds:Q69714317-F7DAC8D4-A882-4759-B629-6117F0DD16F6
issue	1
volume	36
DOI	wds:Q69714317-15283D75-45CB-4BD2-BC62-41AEF46B2B4A
DOI	http://dx.doi.org/10.1016/0006-2952(87)90392-3
DOI	10.1016/0006-2952(87)90392-3
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q69714317
is cites work of	Clinical studies of reversal of drug resistance based on glutathione. Ovarian cancer: strategies for overcoming resistance to chemotherapy Determination of thiols and disulfides via HPLC quantification of 5-thio-2-nitrobenzoic acid Mechanisms of drug resistance in ovarian cancer Glutathione deficiency produced by inhibition of its synthesis, and its reversal; Applications in research and therapy L-S,R-buthionine sulfoximine: historical development and clinical issues Harnessing drug resistance: using ABC transporter proteins to target cancer cells Intra-arterial chemotherapy with osmotic blood-brain barrier disruption for aggressive oligodendroglial tumors: results of a phase I study Modulation of antitumor alkylating agents (AA) Systemic chemotherapy for malignant melanoma Resistance factors in colon cancer tissue and the adjacent normal colon tissue: glutathione S-transferases alpha and pi, glutathione and aldehyde dehydrogenase. Sensitivity of melphalan-resistant tumors to selenite in vivo. Changes in cellular glutathione content during adriamycin treatment in human ovarian cancer--a possible indicator of chemosensitivity Modulation of glutathione conjugation in vivo: how to decrease glutathione conjugation in vivo or in intact cellular systems in vitro Clinical drug resistance: the role of factors other than P-glycoprotein In vivo therapeutic potential of combination thiol depletion and alkylating chemotherapy Modulation of cytostatic efficacy of melphalan by glutathione: mechanisms and efficacy Effect of glutathione depletion on inhibition of cell cycle progression and induction of apoptosis by melphalan (L-phenylalanine mustard) in human colorectal cancer cells Historical aspects of glutathione and cancer chemotherapy Flow cytometric measurement of glutathione content of human cancer biopsies. Intracellular glutathione content of urothelial cancer in correlation to chemotherapy response. Do glutathione and related enzymes play a role in drug resistance in small cell lung cancer cell lines? Nitrogen mustard-DNA interaction in melphalan-resistant mammary carcinoma cells with elevated intracellular glutathione and glutathione-S-transferase activity Buthionine sulfoximine-induced cytostasis does not correlate with glutathione depletion Resistance to cytostatic drugs at the cellular level Melanin content and downregulation of glutathione S-transferase contribute to the action of L-buthionine-S-sulfoximine on human melanoma Characterization of the inhibition of glutathione reductase and the recovery of enzyme activity in exponentially growing murine leukemia (11210) cells treated with 1,3-bis(2-chloroethyl)-1-nitrosourea Buthionine sulphoximine alone and in combination with melphalan (L-PAM) is highly cytotoxic for human neuroblastoma cell lines Melphalan-induced toxicity in nude mice following pretreatment with buthionine sulfoximine. Drug resistance in myeloma: mechanisms and approaches to circumvention Antineoplastic Drug Resistance in Brain Tumors Effect of selenium compounds and thiols on human mammary tumor cells Usefulness of (99m)Tc-d,l-HMPAO for estimation of GSH content in tumor tissues Role of the oxidized form of XRCC1 in protection against extreme oxidative stress Photodynamic therapy using Photofrin in combination with buthionine sulfoximine (BSO) to treat 9L gliosarcoma in rat brain The influence of glutathione metabolism on multidrug resistance in MRP-overexpressing cells Nitric oxide enhancement of melphalan-induced cytotoxicity Analytical and preparative separation of the diastereomers of l-buthionine (SR)-sulfoximine, a potent inhibitor of glutathione biosynthesis Potential of l-buthionine sulfoximine to enhance the apoptotic action of estradiol to reverse acquired antihormonal resistance in metastatic breast cancer

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