About: Relation of positive inotropic and chronotropic effects of pimobendan, UD-CG 212 Cl, milrinone and other phosphodiesterase inhibitors to phosphodiesterase III inhibition in guinea-pig heart

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About: Relation of positive inotropic and chronotropic effects of pimobendan, UD-CG 212 Cl, milrinone and other phosphodiesterase inhibitors to phosphodiesterase III inhibition in guinea-pig heart Goto Sponge NotDistinct Permalink

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scientific article published on 01 May 1989

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) bài báo khoa học (vi) наукова стаття, опублікована в травні 1989 (uk) im Mai 1989 veröffentlichter wissenschaftlicher Artikel (de) artículu científicu espublizáu en mayu de 1989 (ast) scientific article published on 01 May 1989 (en)
publication date	wds:Q69355237-B974F544-DD98-42DA-A259-11CE13AA8377
publication date	1989-05-01 00:00:00Z (xsd:dateTime)
exact match	wds:Q69355237-C9928450-22CA-4E1D-B1E1-3767EDF02E66
exact match	https://scigraph.springernature.com/pub.10.1007/bf00167264
cites work	wds:Q69355237-0D38B6BB-B3D1-4512-857A-4ADA49AE9DE0 wds:Q69355237-11F8FBEC-3D4A-4BD9-AF5A-926F4AB512AB wds:Q69355237-13CC1767-6879-4B1C-B500-805FFD696E63 wds:Q69355237-208B2081-C8C2-442A-AF37-B14B3D0F05C2 wds:Q69355237-21516357-1CE6-42AC-8A94-D540D9D0A0CB wds:Q69355237-24F3ACEA-03C3-4FE8-AAB6-59BA293E387B wds:Q69355237-28A6C289-FFB2-4C3D-A774-BBDB9920C51F wds:Q69355237-2D2F4B08-4E98-43E5-B0E5-7DB66ACBEF1F wds:Q69355237-2DF0A8CD-5C54-4EB7-B25B-6E68DA4ABA0C wds:Q69355237-3079138F-E587-4C38-B3ED-FF7C31A67DC0 wds:Q69355237-319A466F-B13B-4E47-ADF4-DEA367EED28C wds:Q69355237-36B03C49-BB57-4510-9B5F-1218F83D4B68 wds:Q69355237-3B53C215-C4A9-4BE5-9685-DAC4400A2F54 wds:Q69355237-7B648CA0-BE0B-4644-83E0-F166F3674547 wds:Q69355237-7FD4F780-3C9B-4E9D-879E-2CDF73CFFC75 wds:Q69355237-80C7DD32-8515-4362-9DD1-08546314C92D wds:Q69355237-8FD9C75B-F4A8-4EB0-8648-8212CEBC6A74 wds:Q69355237-A3436FEB-1649-4359-B2AB-47F7F63BBD54 wds:Q69355237-AA87C343-60C3-4CEC-8208-43C7C5E69406 wds:Q69355237-AEA18229-72A2-4925-B0EF-CA586AADB2B5 wds:Q69355237-AEC71633-0539-4F9E-91E6-B4AFAF798E3F wds:Q69355237-C7A47516-BD3E-4066-B298-C6BF4BE21075 wds:Q69355237-CB28A153-CB9C-4B6A-AC9F-6CA4C4F9949B wds:Q69355237-D46D31AC-4B99-44F1-AD27-AA9BB9D47E01 wds:Q69355237-E1D7B478-AC64-4A7B-A0E9-9F3008B4282E wds:Q69355237-F5BAC897-6E75-4648-B47F-1BC68901B421 wds:Q69355237-FB6801BC-07A5-4655-9E0A-8F169D615889 wds:Q69355237-FE7C9957-F1C0-4EC2-85C6-2C4D29AE7E49
cites work	Multiple molecular forms of cyclic nucleotide phosphodiesterase in cardiac and smooth muscle and in platelets. Isolation, characterization, and effects of various reference phosphodiesterase inhibitors and cardiotonic agents Mechanism of action and cardiotonic activity of a new phosphodiesterase inhibitor, the benzimidazole derivative adibendan (BM 14.478), in guinea-pig hearts New positive inotropic agents in the treatment of congestive heart failure. Mechanisms of action and recent clinical developments. 1. Effects of antiallergic agents, compound 48/80, and some reference inhibitors on the activity of partially purified human lung tissue adenosine cyclic 3',5'-monophosphate and guanosine cyclic 3',5'-monophosphate phosphodiesterases A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding 4-(3-Cyclopentyloxy-4-methoxyphenyl)-2-pyrrolidone (ZK 62711): a potent inhibitor of adenosine cyclic 3',5'-monophosphate phosphodiesterases in homogenates and tissue slices from rat brain Isolation and characterization of bovine cardiac muscle cGMP-inhibited phosphodiesterase: a receptor for new cardiotonic drugs A new generation of phosphodiesterase inhibitors: multiple molecular forms of phosphodiesterase and the potential for drug selectivity Pharmacology of the bipyridines: amrinone and milrinone. Effect of milrinone (Corotrope) on the contractility of isolated dog ventricular muscle Phosphodiesterase-inhibiting properties of newer inotropic agents Molecular basis for the cardiovascular activities of amrinone and AR-L57. Assay of cyclic nucleotide phosphodiesterase and resolution of multiple molecular forms of the enzyme Effects of the benzimidazole derivatives pimobendan and 2-(4-hydroxy-phenyl)-5-(5-methyl-3-oxo-4,5-dihydro-2H-6- pyridazinyl) benzimidazole . HCl on phosphodiesterase activity and force of contraction in guinea-pig hearts. Effects of new inotropic agents on Ca++ sensitivity of contractile proteins Effect on contractility of skinned fibres from mammalian heart and smooth muscle by a new benzimidazole derivative, 4,5-dihydro-6-[2-(4-methoxyphenyl)-1H-benzimidazol-5-yl]-5-methy l-3(2H )- pyridazinone The identification of a new cyclic nucleotide phosphodiesterase activity in human and guinea-pig cardiac ventricle. Implications for the mechanism of action of selective phosphodiesterase inhibitors UD-CG 115 ? a cardiotonic pyridazinone which elevates cyclic AMP and prolongs the action potential in guinea-pig papillary muscle Subclasses of cyclic AMP-specific phosphodiesterase in left ventricular muscle and their involvement in regulating myocardial contractility The positive inotropic response to milrinone in isolated human and guinea pig myocardium Sensitization of dog and guinea pig heart myofilaments to Ca2+ activation and the inotropic effect of pimobendan: comparison with milrinone In search of the digitalis replacement Effects of several phosphodiesterase-inhibitors on guinea-pig myocardium Comparative cardiovascular effects of three benzimidazole derivatives, AR-L 57 BS, AR-L 100 BS, and AR-L 115 BS. Usefulness of pimobendan in the treatment of heart failure Overview of cardiac inotropic mechanisms. Effects of some cardiotonic agents on contractility of skinned fibers from mammalian heart. A comparison of the cardiotonic effects of AR-L115 and AR-L57: evidence for distinct inotropic mechanisms.
author name string	wds:Q69355237-14BFE42B-0271-4304-91D5-DD2DAC8FE620 wds:Q69355237-221AF441-19E0-498F-8258-C56C48A2D6AD wds:Q69355237-269B942D-3632-4B13-ACFD-3157F5D5903E wds:Q69355237-9E2C9E49-EF85-4ABE-BF66-A95077DAC9CB wds:Q69355237-C30A59FB-4775-44F7-96BC-0985C974CC8E wds:Q69355237-E6116345-E5E1-433F-8C0B-3C72FA0D6701
author name string	W Meyer H Scholz D Brunkhorst R Nigbur C Schmidt-Schumacher H v der Leyen
rdfs:label	Relation of positive inotropic and chronotropic effects of pimobendan, UD-CG 212 Cl, milrinone and other phosphodiesterase inhibitors to phosphodiesterase III inhibition in guinea-pig heart (en) Relation of positive inotropic and chronotropic effects of pimobendan, UD-CG 212 Cl, milrinone and other phosphodiesterase inhibitors to phosphodiesterase III inhibition in guinea-pig heart (nl)
skos:prefLabel	Relation of positive inotropic and chronotropic effects of pimobendan, UD-CG 212 Cl, milrinone and other phosphodiesterase inhibitors to phosphodiesterase III inhibition in guinea-pig heart (en) Relation of positive inotropic and chronotropic effects of pimobendan, UD-CG 212 Cl, milrinone and other phosphodiesterase inhibitors to phosphodiesterase III inhibition in guinea-pig heart (nl)
name	Relation of positive inotropic and chronotropic effects of pimobendan, UD-CG 212 Cl, milrinone and other phosphodiesterase inhibitors to phosphodiesterase III inhibition in guinea-pig heart (en) Relation of positive inotropic and chronotropic effects of pimobendan, UD-CG 212 Cl, milrinone and other phosphodiesterase inhibitors to phosphodiesterase III inhibition in guinea-pig heart (nl)
title	wds:Q69355237-197BB9F0-A122-4110-AF1E-AE39F3560B32
title	Relation of positive inotropic and chronotropic effects of pimobendan, UD-CG 212 Cl, milrinone and other phosphodiesterase inhibitors to phosphodiesterase III inhibition in guinea-pig heart (en)
page(s)	wds:Q69355237-F6516088-8A2B-4571-B66A-24AFCA37D5A1
page(s)	575-583
instance of	wds:Q69355237-8119A976-B96A-44F5-ABFD-04E9C2031F78
instance of	scholarly article
main subject	wds:Q69355237-1DC335CD-4B92-40B8-9C26-A342C6890423 wds:Q69355237-E82172C5-65DD-43FF-9DF1-FF93D33F152B
main subject	wd:Q847399 pig
PubMed ID	wds:Q69355237-B67A51C1-C93B-4733-AA77-C04606D09833
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/2549430
PubMed ID	2549430
published in	wds:Q69355237-1DE3E276-EB0B-4850-BBF3-21B622CE8E87
published in	Naunyn-Schmiedeberg's Archives of Pharmacology

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