About: Mitchell Lazar

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An Entity of Type : wikibase:Item, within Data Space : wikidata.demo.openlinksw.com associated with source document(s)

Endocrinologist and physician-scientist

Attributes	Values
rdf:type	Item
description	forskare (sv) ikertzailea (eu) 연구원 (ko) 研究者 (ja) araştırmacı (tr) эрдэмтэн (mn) изилдөөчү (ky) 研究者 (zh) US-amerikanischer Mediziner (de) endocrinoloog (nl) Endocrinologist and physician-scientist (en)
rdfs:label	Mitchell A Lazar (nl) Mitchell A. Lazar (de) Mitchell Lazar (en) Mitchell Lazar (es) Mitchell Lazar (fr) Mitchell Lazar (it) Mitchell Lazar (ast)
skos:prefLabel	Mitchell A Lazar (nl) Mitchell A. Lazar (de) Mitchell Lazar (en) Mitchell Lazar (es) Mitchell Lazar (fr) Mitchell Lazar (it) Mitchell Lazar (ast)
name	Mitchell A Lazar (nl) Mitchell A. Lazar (de) Mitchell Lazar (en) Mitchell Lazar (es) Mitchell Lazar (fr) Mitchell Lazar (it) Mitchell Lazar (ast)
Freebase ID	wds:Q6881291-FC6FD394-4BFB-4DA7-A6C4-91D40AE5ACBB
Freebase ID	/m/0h3nmcw
given name	wds:Q6881291-09632E31-6637-4973-9424-AE5903CCB198 wds:Q6881291-c97b42c9-4f2e-7f3b-1b19-d113323c9b90
given name	Avery Mitchell
instance of	wds:Q6881291-E063E018-748C-4CED-BD52-5A46EBD7C301
instance of	Homo sapiens
award received	wds:Q6881291-e9c4e20b-4c53-a748-bead-9378fa4f9be8
award received	Stanley J. Korsmeyer Award
skos:altLabel	Mitchell A Lazar (en) Mitchell Avery Lazar (de) Mitchell Lazar (de)
occupation	wds:Q6881291-4431913C-044E-40A6-8534-B9BE375A85F2 wds:Q6881291-5832AB95-A9F3-4FBB-BB88-DAF0DFE4440E
employer	wds:Q6881291-48836F61-C935-4C9D-BB14-7F5006CBBA7C
languages spoken, written or signed	wds:Q6881291-9595f2ca-4b66-5689-a474-efb00cdb5b47
sex or gender	wds:Q6881291-F633CFDA-59DC-42D3-9E1B-55D1AB0BD370
VIAF ID	wds:Q6881291-18d758cc-472c-8471-075a-d57e1a7d8f1d
Library of Congress authority ID	wds:Q6881291-d0038532-4992-6e29-8e21-479179fae2d1
country of citizenship	wds:Q6881291-822165d6-47ec-1cde-5cb8-30fcc4efe519
member of	wds:Q6881291-ABA28FFD-1832-4EA6-B94F-AFEE8A0C3952
date of birth	wds:Q6881291-D5CF922F-62DC-46B1-9460-95CEE7E9F3FA
educated at	wds:Q6881291-CEBD1C23-EFBA-422E-80CB-A054CBCE3364 wds:Q6881291-D596C810-E779-4459-90A6-6560E21D00F7 wds:Q6881291-E044098D-6735-45C5-9E29-EA4A95EC1534
family name	wds:Q6881291-a58b57b4-4810-e958-00aa-d829c9aad91d
VIAF ID	http://viaf.org/viaf/269538740
Library of Congress authority ID	http://id.loc.gov/authorities/names/n87141143
occupation	endocrinologist researcher
employer	University of Pennsylvania
languages spoken, written or signed	English
sex or gender	male
VIAF ID	269538740
Library of Congress authority ID	n87141143
country of citizenship	United States of America
member of	American Academy of Arts and Sciences
date of birth	1956-01-01 00:00:00Z (xsd:dateTime)
educated at	Stanford University School of Medicine Massachusetts Institute of Technology Syosset High School
family name	Lazar
ORCID iD	wds:Q6881291-92B6569B-C0B9-4DBE-B983-4986FF3BBCC6
ORCID iD	https://orcid.org/0000-0001-8653-1280
ORCID iD	0000-0001-8653-1280
is owl:sameAs of	Mitchell Lazar
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q6881291 Mitchell Lazar https://de.wikipedia.org/wiki/Mitchell_A._Lazar
is author of	Deacetylase-independent function of HDAC3 in transcription and metabolism requires nuclear receptor corepressor Genetic Variation Determines PPARγ Function and Anti-diabetic Drug Response In Vivo. Genomic redistribution of GR monomers and dimers mediates transcriptional response to exogenous glucocorticoid in vivo Anti-diabetic rosiglitazone remodels the adipocyte transcriptome by redistributing transcription to PPARγ-driven enhancers PRDM16 binds MED1 and controls chromatin architecture to determine a brown fat transcriptional program. Regeneration of fat cells from myofibroblasts during wound healing. Rev-erbα dynamically modulates chromatin looping to control circadian gene transcription. Histone deacetylase 3 prepares brown adipose tissue for acute thermogenic challenge. Targeting PPARγ in the epigenome rescues genetic metabolic defects in mice. SR9009 has REV-ERB-independent effects on cell proliferation and metabolism Circadian lipid synthesis in brown fat maintains murine body temperature during chronic cold REV-ERB nuclear receptors in the suprachiasmatic nucleus control circadian period and restrict diet-induced obesity Identification of C2CD4A as a human diabetes susceptibility gene with a role in β cell insulin secretion Shining light on dark matter in the genome Dichotomous engagement of HDAC3 activity governs inflammatory responses A coregulator shift, rather than the canonical switch, underlies thyroid hormone action in the liver The hepatocyte clock and feeding control chronophysiology of multiple liver cell types

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