About: Influence of benzo[a]pyrene diol epoxide chirality on solution conformations of DNA covalent adducts: the (-)-trans-anti-[BP]G.C adduct structure and comparison with the (+)-trans-anti-[BP]G.C enantiomer

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About: Influence of benzo[a]pyrene diol epoxide chirality on solution conformations of DNA covalent adducts: the (-)-trans-anti-[BP]G.C adduct structure and comparison with the (+)-trans-anti-[BP]G.C enantiomer Goto Sponge NotDistinct Permalink

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scientific article published on 01 June 1992

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в червні 1992 (uk) artículu científicu espublizáu en xunu de 1992 (ast) im Juni 1992 veröffentlicher wissenschaftlicher Artikel (de) scientific article published on 01 June 1992 (en)
publication date	wds:Q68156944-75123649-B650-476A-A2BC-4AAF95342364
publication date	1992-06-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q68156944-CE2E1D65-75CA-427E-952F-0987DACB6265
language of work or name	English
author name string	wds:Q68156944-0F104925-DC8A-4142-BD39-2DA435E77B28 wds:Q68156944-1D45148F-D5B7-4FCD-BCE0-B704AD8A41C9 wds:Q68156944-67180ADE-E235-49BA-BEA1-A899BA130A8C wds:Q68156944-6B85DF86-F57D-4613-B1D3-ACACCD96C32A wds:Q68156944-85CDA727-09CA-45F9-99C6-FDFB99433403 wds:Q68156944-AD818FFC-85E9-4579-B65C-DAF0E26BBD9B wds:Q68156944-EBAD24D8-7A32-4C40-8392-B31FF24BA58E wds:Q68156944-F15CBF45-E260-4EC0-A145-B6C659424162
author name string	D J Patel C de los Santos B E Hingerty S Broyde N E Geacintov V Ibanez M Cosman L A Margulis
rdfs:label	Influence of benzo[a]pyrene diol epoxide chirality on solution conformations of DNA covalent adducts: the (nl) Influence of benzo[a]pyrene diol epoxide chirality on solution conformations of DNA covalent adducts: the (-)-trans-anti-[BP]G.C adduct structure and comparison with the (+)-trans-anti-[BP]G.C enantiomer (en)
skos:prefLabel	Influence of benzo[a]pyrene diol epoxide chirality on solution conformations of DNA covalent adducts: the (nl) Influence of benzo[a]pyrene diol epoxide chirality on solution conformations of DNA covalent adducts: the (-)-trans-anti-[BP]G.C adduct structure and comparison with the (+)-trans-anti-[BP]G.C enantiomer (en)
name	Influence of benzo[a]pyrene diol epoxide chirality on solution conformations of DNA covalent adducts: the (nl) Influence of benzo[a]pyrene diol epoxide chirality on solution conformations of DNA covalent adducts: the (-)-trans-anti-[BP]G.C adduct structure and comparison with the (+)-trans-anti-[BP]G.C enantiomer (en)
title	wds:Q68156944-BC2440D4-DECC-41A5-BE6E-79B3F7AFEABD
title	Influence of benzo[a]pyrene diol epoxide chirality on solution conformations of DNA covalent adducts: the (-)-trans-anti-[BP]G.C adduct structure and comparison with the (+)-trans-anti-[BP]G.C enantiomer (en)
page(s)	wds:Q68156944-5B8BF4BC-1CE9-45A7-B8E8-952F69336050
page(s)	5245-5252
instance of	wds:Q68156944-4BBE4297-1074-44B2-B880-44DE127CCEA5
instance of	scholarly article
main subject	wds:Q68156944-0539AF51-D344-425B-BB08-C90952B9F386 wds:Q68156944-EB241380-AAFF-48D4-804A-9A11E8D04255
main subject	enantiomer chirality
PubMed ID	wds:Q68156944-5546F076-CD68-443A-A05A-7FBD6BE7EEF0
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/1606148
PubMed ID	1606148
published in	wds:Q68156944-954A8B93-88C8-4E34-9502-E49F266E77EF
published in	Biochemistry
issue	wds:Q68156944-A4705C06-B60C-4639-8600-578DA176F0C2
volume	wds:Q68156944-760272AD-8DB4-4FD6-8F06-C86E9CE070FB
issue	23
volume	31
number of pages	wds:Q68156944-BD68EBC3-B76A-4CC0-91A3-4320660DA318
number of pages	8 (xsd:decimal)
DOI	wds:Q68156944-30047A10-3B42-42ED-B3FE-B435302F2426
DOI	http://dx.doi.org/10.1021/BI00138A002
DOI	10.1021/BI00138A002
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q68156944
is cites work of	Adenine-DNA adducts derived from the highly tumorigenic Dibenzo[a,l]pyrene are resistant to nucleotide excision repair while guanine adducts are not The human DNA repair factor XPC-HR23B distinguishes stereoisomeric benzo[a]pyrenyl-DNA lesions Recognition of DNA damage by the Rad4 nucleotide excision repair protein DNA adducts from a tumorigenic metabolite of benzo[a]pyrene block human RNA polymerase II elongation in a sequence- and stereochemistry-dependent manner Thermodynamic profiles and nuclear magnetic resonance studies of oligonucleotide duplexes containing single diastereomeric spiroiminodihydantoin lesions Simulating structural and thermodynamic properties of carcinogen-damaged DNA. Nucleotide excision repair efficiencies of bulky carcinogen-DNA adducts are governed by a balance between stabilizing and destabilizing interactions Chemistry and structural biology of DNA damage and biological consequences Crystal and molecular structure of a benzo[a]pyrene 7,8-diol 9,10-epoxide N2-deoxyguanosine adduct: absolute configuration and conformation Molecular modeling of the major benzo[a]pyrene N2-dG adduct in cases where mutagenesis results are known in double stranded DNA. Nuclear Magnetic Resonance Solution Structure of an N 2 -Guanine DNA Adduct Derived from the Potent Tumorigen Dibenzo[ a , l ]pyrene: Intercalation from the Minor Groove with Ruptured Watson–Crick Base Pairing Nuclear Magnetic Resonance Studies of an N 2 -Guanine Adduct Derived from the Tumorigen Dibenzo[ a , l ]pyrene in DNA: Impact of Adduct Stereochemistry, Size, and Local DNA Sequence on Solution Conformations The relationships between XPC binding to conformationally diverse DNA adducts and their excision by the human NER system: is there a correlation? Stereochemistry-dependent bending in oligonucleotide duplexes induced by site-specific covalent benzo[a]pyrene diol epoxide-guanine lesions 3′-Intercalation of a N 2 -dG 1 R - trans - anti -Benzo[ c ]phenanthrene DNA Adduct in an Iterated (CG) 3 Repeat Exocyclic amino groups of flanking guanines govern sequence-dependent adduct conformations and local structural distortions for minor groove-aligned benzo[a]pyrenyl-guanine lesions in a GG mutation hotspot context Poleta, Polzeta and Rev1 together are required for G to T transversion mutations induced by the (+)- and (-)-trans-anti-BPDE-N2-dG DNA adducts in yeast cells Base pair conformation-dependent excision of benzo[a]pyrene diol epoxide-guanine adducts by human nucleotide excision repair enzymes Toward an understanding of the role of DNA adduct conformation in defining mutagenic mechanism based on studies of the major adduct (formed at N(2)-dG) of the potent environmental carcinogen, benzo[a]pyrene In vivo and in vitro replication consequences of stereoisomeric benzo[a]pyrene-7,8-dihydrodiol 9,10-epoxide adducts on adenine N6 at the second position of N-ras codon 61. Chloride ions catalyze the formation of cis adducts in the binding of anti-benzo[a]pyrene diol epoxide to nucleic acids DNA damage can alter the stability of nucleosomes: effects are dependent on damage type Methylation of cytosine at C5 in a CpG sequence context causes a conformational switch of a benzo[a]pyrene diol epoxide-N2-guanine adduct in DNA from a minor groove alignment to intercalation with base displacement A single site-specific trans-opened 7,8,9,10-tetrahydrobenzo[a]pyrene 7,8-diol 9,10-epoxide N2-deoxyguanosine adduct induces mutations at multiple sites in DNA. Site-specific DNA transesterification by vaccinia topoisomerase: effects of benzo[alpha]pyrene-dA, 8-oxoguanine, 8-oxoadenine and 2-aminopurine modifications Different effects on human topoisomerase I by minor groove and intercalated deoxyguanosine adducts derived from two polycyclic aromatic hydrocarbon diol epoxides at or near a normal cleavage site Resistance to Nucleotide Excision Repair of Bulky Guanine Adducts Opposite Abasic Sites in DNA Duplexes and Relationships between Structure and Function Repair-Resistant DNA Lesions Molecular dynamics simulations of excimer forming (+)-anti-BPDE-DNA adducts in aqueous solution Dnmt3a-CD is less susceptible to bulky benzo[a]pyrene diol epoxide-derived DNA lesions than prokaryotic DNA methyltransferases. Lesion sensing during initial binding by yeast XPC/Rad4: toward predicting resistance to nucleotide excision repair Differences in unwinding of supercoiled DNA induced by the two enantiomers of anti-benzo[a]pyrene diol epoxide Position-specific suppression and enhancement of HIV-1 integrase reactions by minor groove benzo[a]pyrene diol epoxide deoxyguanine adducts: implications for molecular interactions between integrase and substrates Distinct roles of RECQ1 in the maintenance of genomic stability Influence of C-5 substituted cytosine and related nucleoside analogs on the formation of benzo[a]pyrene diol epoxide-dG adducts at CG base pairs of DNA. Conformational searches elucidate effects of stereochemistry on structures of deoxyadenosine covalently bound to tumorigenic metabolites of benzo[C] phenanthrene. Volume changes accompanying interaction of ligands with nucleic acids Mechanism of error-free replication across benzo[a]pyrene stereoisomers by Rev1 DNA polymerase Simultaneous detection of nucleotide excision repair events and apoptosis-induced DNA fragmentation in genotoxin-treated cells. Incorporation of 3-aminobenzanthrone into 2'-deoxyoligonucleotides and its impact on duplex stability Benzo[a]pyrene diol epoxide-DNA cis adduct formation through a trans chlorohydrin intermediate. Probing murine methyltransfease Dnmt3a interactions with benzo[a]pyrene-modified DNA by fluorescence methods Mutagenic Replication of N2-Deoxyguanosine Benzo[a]pyrene Adducts by Escherichia coli DNA Polymerase I and Sulfolobus solfataricus DNA Polymerase IV.

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