About: Acetaminophen-induced cytotoxicity in cultured mouse hepatocytes: effects of Ca(2+)-endonuclease, DNA repair, and glutathione depletion inhibitors on DNA fragmentation and cell death

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About: Acetaminophen-induced cytotoxicity in cultured mouse hepatocytes: effects of Ca(2+)-endonuclease, DNA repair, and glutathione depletion inhibitors on DNA fragmentation and cell death Goto Sponge NotDistinct Permalink

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scientific article published on 01 January 1992

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в січні 1992 (uk) im Januar 1992 veröffentlichter wissenschaftlicher Artikel (de) artículu científicu espublizáu en xineru de 1992 (ast) artikull shkencor i botuar më 01 janar 1992 (sq) scientific article published on 01 January 1992 (en)
publication date	wds:Q67485782-8C258FC2-F06C-4B59-9517-9D4BDDEBB811
publication date	1992-01-01 00:00:00Z (xsd:dateTime)
author name string	wds:Q67485782-0D33F18F-8A74-479F-ADE6-4A41A6B128E4 wds:Q67485782-24820E33-A00B-44CC-8C05-2A0098163583 wds:Q67485782-AF82227E-7034-4080-834A-5131813268CF
author name string	W Shen S D Ray L M Kamendulis
rdfs:label	Acetaminophen-induced cytotoxicity in cultured mouse hepatocytes: effects of Ca(2+)-endonuclease, DNA repair, and glutathione depletion inhibitors on DNA fragmentation and cell death (en) Acetaminophen-induced cytotoxicity in cultured mouse hepatocytes: effects of Ca(2+)-endonuclease, DNA repair, and glutathione depletion inhibitors on DNA fragmentation and cell death (nl) Acetaminophen-induced cytotoxicity in cultured mouse hepatocytes: effects of Ca(2+)-endonuclease, DNA repair, and glutathione depletion inhibitors on DNA fragmentation and cell death (sq)
skos:prefLabel	Acetaminophen-induced cytotoxicity in cultured mouse hepatocytes: effects of Ca(2+)-endonuclease, DNA repair, and glutathione depletion inhibitors on DNA fragmentation and cell death (en) Acetaminophen-induced cytotoxicity in cultured mouse hepatocytes: effects of Ca(2+)-endonuclease, DNA repair, and glutathione depletion inhibitors on DNA fragmentation and cell death (nl) Acetaminophen-induced cytotoxicity in cultured mouse hepatocytes: effects of Ca(2+)-endonuclease, DNA repair, and glutathione depletion inhibitors on DNA fragmentation and cell death (sq)
name	Acetaminophen-induced cytotoxicity in cultured mouse hepatocytes: effects of Ca(2+)-endonuclease, DNA repair, and glutathione depletion inhibitors on DNA fragmentation and cell death (en) Acetaminophen-induced cytotoxicity in cultured mouse hepatocytes: effects of Ca(2+)-endonuclease, DNA repair, and glutathione depletion inhibitors on DNA fragmentation and cell death (nl) Acetaminophen-induced cytotoxicity in cultured mouse hepatocytes: effects of Ca(2+)-endonuclease, DNA repair, and glutathione depletion inhibitors on DNA fragmentation and cell death (sq)
author	wds:Q67485782-6BC30EAE-A5A4-46A4-A4DB-F103AD739071
author	George Corcoran
title	wds:Q67485782-7DF2C076-9F81-4F31-897A-92FB5BDC0504
title	Acetaminophen-induced cytotoxicity in cultured mouse hepatocytes: effects of Ca(2+)-endonuclease, DNA repair, and glutathione depletion inhibitors on DNA fragmentation and cell death (en)
page(s)	wds:Q67485782-7BF11579-8F21-4289-9F5A-E4DC30383340
page(s)	32-40
instance of	wds:Q67485782-53CEA83E-D24A-450A-AFCB-0A13BE773239
instance of	scholarly article
main subject	wds:Q67485782-C6B7CDAC-A188-4052-BD0A-8CB53CA25DCA wds:Q67485782-CF521EEC-FB24-4148-84BB-CB88541CA546 wds:Q67485782-F39307BB-A3FC-43A7-8FBA-0926FEF39D35
main subject	cell death cytotoxicity glutathione
PubMed ID	wds:Q67485782-AE9A2221-1F0E-4C11-AC69-3403B2411B55
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/1310169
PubMed ID	1310169
published in	wds:Q67485782-F3347B15-1BB2-43AA-BD2F-F9E2EA425BDE
published in	Toxicology and Applied Pharmacology
issue	wds:Q67485782-81B46271-6B04-4710-AF2C-0329A61E3482
volume	wds:Q67485782-D95CEABA-D127-4044-BE9B-30EDAE01AD68
issue	1
volume	112
DOI	wds:Q67485782-64F8CC5F-B62F-4680-AED4-A78FE192E6DE
DOI	http://dx.doi.org/10.1016/0041-008X(92)90276-X
DOI	10.1016/0041-008X(92)90276-X
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q67485782
is cites work of	Mechanisms of acetaminophen-induced liver necrosis Apoptosis-inducing factor modulates mitochondrial oxidant stress in acetaminophen hepatotoxicity Experimental models of hepatotoxicity related to acute liver failure The mechanism underlying acetaminophen-induced hepatotoxicity in humans and mice involves mitochondrial damage and nuclear DNA fragmentation Oxidant stress, mitochondria, and cell death mechanisms in drug-induced liver injury: lessons learned from acetaminophen hepatotoxicity Acetaminophen induces a caspase-dependent and Bcl-XL sensitive apoptosis in human hepatoma cells and lymphocytes. Apoptosis versus oncotic necrosis in hepatic ischemia/reperfusion injury Liver apoptosis Plasminogen activator inhibitor-1 limits liver injury and facilitates regeneration after acetaminophen overdose The cyanobacterial toxin, microcystin-LR, can induce apoptosis in a variety of cell types Acetaminophen-induced Liver Injury: from Animal Models to Humans Mechanism of gastroprotection by bismuth subsalicylate against chemically induced oxidative stress in cultured human gastric mucosal cells Acetaminophen selectively reduces glioma cell growth and increases radiosensitivity in culture. Molecular basis of pathophysiology of Indian childhood cirrhosis: role of nuclear copper accumulation in liver Prevention of PC12 cell death by N-acetylcysteine requires activation of the Ras pathway Rapid DNA degradation in primary rat hepatocytes treated with diverse cytotoxic chemicals: analysis by pulsed field gel electrophoresis and implications for alkaline elution assays. Zebularine upregulates expression of CYP genes through inhibition of DNMT1 and PKR in HepG2 cells Deoxyribonuclease 1 aggravates acetaminophen-induced liver necrosis in male CD-1 mice. Toxicological studies with primary cultures of chick embryo cells: DNA fragmentation under the influence of DNase I-inhibitors Chromatin breakdown by deoxyribonuclease1 promotes acetaminophen-induced liver necrosis: an ultrastructural and histochemical study on male CD-1 mice Different Contribution of Redox-Sensitive Transient Receptor Potential Channels to Acetaminophen-Induced Death of Human Hepatoma Cell Line. The impact of partial manganese superoxide dismutase (SOD2)-deficiency on mitochondrial oxidant stress, DNA fragmentation and liver injury during acetaminophen hepatotoxicity Models of drug-induced liver injury for evaluation of phytotherapeutics and other natural products. Pharmacological interventions of cyanide-induced cytotoxicity and DNA damage in isolated rat thymocytes and their protective efficacy in vivo Resistance of three immortalized human hepatocyte cell lines to acetaminophen and N-acetyl-p-benzoquinoneimine toxicity Acute and chronic stress-induced oxidative gastrointestinal mucosal injury in rats and protection by bismuth subsalicylate Hepatoprotective potential of Phyllanthus muellarianus leaf extract: studies on hepatic, oxidative stress and inflammatory biomarkers. Acetaminophen from liver to brain: New insights into drug pharmacological action and toxicity Inhibition of Glutathione Biosynthesis Sensitizes Plasmodium berghei to Antifolates Trifluoperazine inhibits acetaminophen-induced hepatotoxicity and hepatic reactive nitrogen formation in mice and in freshly isolated hepatocytes. DNA Damage Response Regulates Initiation of Liver Regeneration Following Acetaminophen Overdose. Mitochondrial K+ as modulator of Ca(2+)-dependent cytotoxicity in hepatocytes. Novel application of the K(+)-sensitive dye PBFI (K(+)-binding benzofuran isophthalate) to assess free mitochondrial K+ concentrations
is cites work of	wds:Q26775293-2407937E-6F9A-4848-A105-27A115C4ADB9 wds:Q30832248-F260B29F-9512-4C11-8C71-481523C3991A wds:Q37598574-47A5F457-A2BE-4438-9FA4-ADF05DE27B00 wds:Q36768942-B3C7A13A-0976-47F0-ACEE-DA8164B71715 wds:Q41515946-183CA914-B0AD-4638-9A0B-2E49FDAC146D wds:Q53475750-A9C74093-0004-4A48-8CC5-2B0798AB2702 wds:Q80387784-F6EA834F-0DEB-4929-8655-A210567AF93E wds:Q37656707-C77FCE66-144C-41C6-9DD8-0F32AB19F6B5 wds:Q37324704-81443FF6-3BD1-4340-8178-F0C358E3C52D wds:Q35858082-22DA0B58-FC97-44C3-94F0-4961162AC2A5 wds:Q50247510-7E95D48D-D733-4EDB-BB6C-F40705BB70B3 wds:Q46914171-6D3C5440-DA9D-49CB-A452-A27F1C2D94D7 wds:Q26781944-F93CD970-7D1D-4D88-85FA-8910333487F4 wds:Q33181828-7B09E68C-5252-4FDE-90E8-88002A0EA081 wds:Q34630779-9BDBD225-9EF6-491A-9F21-8E8D188D8DC7 wds:Q27308057-1566ED83-92B9-4697-A92F-D0F7A5A1FE7F wds:Q38786694-EFFE9866-72FF-4BD5-A05D-310A1BF130B5

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