About: Direct, convergent hypersensitivity of calcium-activated force generation produced by hypertrophic cardiomyopathy mutant alpha-tropomyosins in adult cardiac myocytes

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Direct, convergent hypersensitivity of calcium-activated force generation produced by hypertrophic cardiomyopathy mutant alpha-tropomyosins in adult cardiac myocytes Goto Sponge NotDistinct Permalink

An Entity of Type : wikibase:Item, within Data Space : wikidata.demo.openlinksw.com associated with source document(s)

article by D E Michele et al published December 1999 in Nature Medicine

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в грудні 1999 (uk) im Dezember 1999 veröffentlichter wissenschaftlicher Artikel (de) article by D E Michele et al published December 1999 in Nature Medicine (en)
publication date	wds:Q64381152-D016DB77-6001-4AAF-A281-738C96231EC0
publication date	1999-12-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q64381152-E1F30C45-C228-4110-BEB6-24FCC0EC5B1F
language of work or name	English
cites work	wds:Q64381152-0AE61DC9-DD7E-4F99-A75F-C0BC38EF34EF wds:Q64381152-0FDBAD15-4A9F-4AD6-9D3F-6AC2092363DF wds:Q64381152-1499F2A8-FB25-44DD-97B7-8D3DD8A76E0B wds:Q64381152-195022F9-9112-4C2A-A3A5-D6B506570993 wds:Q64381152-1E170F2F-5F46-4B9B-AB18-AC598004B1A3 wds:Q64381152-240D47B2-7CE8-40AC-8672-31A1C71912EB wds:Q64381152-241BBA68-AD57-4E2B-AF65-EB6226CC593F wds:Q64381152-29F2E90E-1AD4-489F-95DE-67C581FD3D44 wds:Q64381152-32BB4F29-C7A1-483C-8757-609B70F5F127 wds:Q64381152-3555CFFE-7F1F-4BAF-B2EB-76782DDE3AB9 wds:Q64381152-36806867-FDF2-4814-88D7-74210CB3EEEF wds:Q64381152-5266CD7E-6AB0-4520-ADEB-8E1FB6613F72 wds:Q64381152-578FCC76-6AF8-47FD-8583-57B9BB1A478A wds:Q64381152-5965AA84-7306-4C05-AC66-B43A4A6BCE7E wds:Q64381152-646A70B3-E9EA-418B-9FCB-429D00C7E071 wds:Q64381152-695022F3-56CA-4192-98A7-48145D639D8A wds:Q64381152-6EDE9FB4-9D47-45D1-BF22-C4E128E2E9A4 wds:Q64381152-7DB445F4-8A0D-4AF6-A471-C1470E2CB847 wds:Q64381152-890276A7-66B3-4556-8321-4A7CD6AC1691 wds:Q64381152-A1A2E9DE-ECE4-4A23-8EAF-4135F08D9062 wds:Q64381152-A2E9D85F-720F-43B4-9CE6-DA74ABCC425E wds:Q64381152-AD9EDDFF-9612-47F7-8E70-F9A367E53471 wds:Q64381152-F148ED72-C8E6-4CF0-B0F3-CFC8C604C331
cites work	Mutations in the genes for cardiac troponin T and alpha-tropomyosin in hypertrophic cardiomyopathy Regulation of the interaction between actin and myosin subfragment 1: evidence for three states of the thin filament Identification of a contractile deficit in adult cardiac myocytes expressing hypertrophic cardiomyopathy-associated mutant troponin T proteins Structure of co-crystals of tropomyosin and troponin Familial hypertrophic cardiomyopathy: from mutations to functional defects Familial hypertrophic cardiomyopathy: a genetic model of cardiac hypertrophy Alpha-tropomyosin and cardiac troponin T mutations cause familial hypertrophic cardiomyopathy: a disease of the sarcomere Differences in clinical expression of hypertrophic cardiomyopathy associated with two distinct mutations in the beta-myosin heavy chain gene. A 908Leu----Val mutation and a 403Arg----Gln mutation A familial hypertrophic cardiomyopathy locus maps to chromosome 15q2. Characteristics and prognostic implications of myosin missense mutations in familial hypertrophic cardiomyopathy Tropomyosin coiled-coil interactions: Evidence for an unstaggered structure Clinical Features of Hypertrophic Cardiomyopathy Caused by Mutation of a “Hot Spot” in the Alpha-Tropomyosin Gene Effects of two hypertrophic cardiomyopathy mutations in alpha-tropomyosin, Asp175Asn and Glu180Gly, on Ca2+ regulation of thin filament motility. A Mutant Tropomyosin That Causes Hypertrophic Cardiomyopathy Is Expressed In Vivo and Associated With an Increased Calcium Sensitivity Mouse model of a familial hypertrophic cardiomyopathy mutation in alpha-tropomyosin manifests cardiac dysfunction Human hTM alpha gene: expression in muscle and nonmuscle tissue Skeletal troponin C reduces contractile sensitivity to acidosis in cardiac myocytes from transgenic mice Thin filament-mediated regulation of cardiac contraction Stability of the contractile assembly and Ca2+-activated tension in adenovirus infected adult cardiac myocytes. Effects of two familial hypertrophic cardiomyopathy-causing mutations on alpha-tropomyosin structure and function. Thin filament protein dynamics in fully differentiated adult cardiac myocytes: toward a model of sarcomere maintenance Novel missense mutation in alpha-tropomyosin gene found in Japanese patients with hypertrophic cardiomyopathy Clinical implications of hypertrophic cardiomyopathy associated with mutations in the alpha-tropomyosin gene
author name string	wds:Q64381152-0AC8F2C6-B351-4520-9495-5618CF8D0CFC wds:Q64381152-1ACD29E5-D0CF-4748-9C0B-7C27F8D0EF4C wds:Q64381152-D888126A-3501-4D71-8999-94D79E33302B
author name string	F P Albayya J M Metzger D E Michele
rdfs:label	Direct, convergent hypersensitivity of calcium-activated force generation produced by hypertrophic cardiomyopathy mutant alpha-tropomyosins in adult cardiac myocytes (en) Direct, convergent hypersensitivity of calcium-activated force generation produced by hypertrophic cardiomyopathy mutant alpha-tropomyosins in adult cardiac myocytes (nl)
skos:prefLabel	Direct, convergent hypersensitivity of calcium-activated force generation produced by hypertrophic cardiomyopathy mutant alpha-tropomyosins in adult cardiac myocytes (en) Direct, convergent hypersensitivity of calcium-activated force generation produced by hypertrophic cardiomyopathy mutant alpha-tropomyosins in adult cardiac myocytes (nl)
name	Direct, convergent hypersensitivity of calcium-activated force generation produced by hypertrophic cardiomyopathy mutant alpha-tropomyosins in adult cardiac myocytes (en) Direct, convergent hypersensitivity of calcium-activated force generation produced by hypertrophic cardiomyopathy mutant alpha-tropomyosins in adult cardiac myocytes (nl)
title	wds:Q64381152-84773BE9-6EE5-4B03-AC18-DFF43B199E27
title	Direct, convergent hypersensitivity of calcium-activated force generation produced by hypertrophic cardiomyopathy mutant alpha-tropomyosins in adult cardiac myocytes (en)
page(s)	wds:Q64381152-DAD50831-53AC-48A8-AF1A-A7E48AB2E87E
page(s)	1413-7
instance of	wds:Q64381152-E1172C9C-F9B3-445D-AD67-31300D5B594A
instance of	scholarly article
main subject	wds:Q64381152-6BB0E98A-8756-423D-9A9B-07D40F87D471
main subject	hypertrophic cardiomyopathy
PubMed ID	wds:Q64381152-DB0A9A62-643B-4198-96B6-613D8F9E6C4B
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/10581085
PubMed ID	10581085
published in	wds:Q64381152-9BF21F8D-26CF-4054-8DCC-28D2F7C009D3
published in	Nature Medicine
issue	wds:Q64381152-13ECE0D2-B9E4-474E-BCD2-5F3292A743DE
volume	wds:Q64381152-ACE90111-6D59-4B6B-89C7-9D0AFE0D937E
issue	12
volume	5
DOI	wds:Q64381152-3B2156FA-036D-4FC4-9DEE-4C8330683514
DOI	http://dx.doi.org/10.1038/70990
DOI	10.1038/70990
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q64381152
is cites work of	Thin filament mutations: developing an integrative approach to a complex disorder Mechanistic heterogeneity in contractile properties of α-tropomyosin (TPM1) mutants associated with inherited cardiomyopathies. Mutations that alter the surface charge of alpha-tropomyosin are associated with dilated cardiomyopathy Defective regulation of contractile function in muscle fibres carrying an E41K beta-tropomyosin mutation The molecular genetic basis for hypertrophic cardiomyopathy Carbon fiber technique for the investigation of single-cell mechanics in intact cardiac myocytes Nuclear tropomyosin and troponin in striated muscle: new roles in a new locale? Hypertrophic cardiomyopathy:a paradigm for myocardial energy depletion Why Is there a Limit to the Changes in Myofilament Ca2+-Sensitivity Associated with Myopathy Causing Mutations? Sarcomeric proteins and familial hypertrophic cardiomyopathy: linking mutations in structural proteins to complex cardiovascular phenotypes Mechanisms of disease: hypertrophic cardiomyopathy Hypertrophic cardiomyopathy: from gene defect to clinical disease

Faceted Search & Find service v1.16.117 as of May 05 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3239 as of May 5 2024, on Linux (x86_64-centos_6-linux-gnu), Single-Server Edition (378 GB total memory, 193 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software