About: and its monomers alleviate liver fibrosis both in mice and LX2 cells by blocking TβR1-Smad2/3 and TNF-α-NF-κB pathways

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About: and its monomers alleviate liver fibrosis both in mice and LX2 cells by blocking TβR1-Smad2/3 and TNF-α-NF-κB pathways Goto Sponge NotDistinct Permalink

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scholarly article by Xing Wan et al published 2019 in American Journal of Translational Research

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) article scientifique publié en 2019 (fr) наукова стаття, опублікована у 2019 (uk) im Januar 2019 veröffentlichter wissenschaftlicher Artikel (de) scholarly article by Xing Wan et al published 2019 in American Journal of Translational Research (en)
publication date	wds:Q64230111-8E00D567-24AB-4D7D-8D3B-784D9C12275D
publication date	2019-01-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q64230111-8ABABA9C-1DC5-4AFC-8936-3D3E81034A38
language of work or name	English
cites work	wds:Q64230111-02215FC1-460C-4ECF-A208-0CB601EDFBCA wds:Q64230111-09D4AC32-EF5A-4D0F-A694-50A4513ADF46 wds:Q64230111-1343F9DB-DCC4-4964-AA4C-BB682F0719FB wds:Q64230111-1F83E4CA-01D3-40E9-9235-96A809846590 wds:Q64230111-35E19896-BA54-4A9F-9F9D-1E954E50906A wds:Q64230111-424FD9DB-E8B3-49A9-A328-D1C85170C15D wds:Q64230111-43DEB3E2-A7CD-46ED-A0ED-1617FD75409D wds:Q64230111-4667BFC5-66AB-4215-9135-1234AEA04705 wds:Q64230111-53506AB0-13D5-4E79-85FE-7AE980F1FFD3 wds:Q64230111-5697E567-C61C-4105-A7EC-5599BF182E4C wds:Q64230111-57E8A0D3-4E67-4AE1-B4FF-A5D678D42867 wds:Q64230111-6395215E-56D9-43FD-BD48-79DEAA3503A9 wds:Q64230111-652D7D77-7136-48E5-BA81-8F066F36C511 wds:Q64230111-6E4AD852-1825-475C-9E3E-47AC3DC81C42 wds:Q64230111-6F3C1432-9863-4B3A-A5F6-D94DCEC6089B wds:Q64230111-88D08EF4-2AD1-40C3-8361-DCF8440D102A wds:Q64230111-8AEABCC6-282A-438B-9949-D287D040F9C2 wds:Q64230111-9087B001-D5D5-444D-B1A9-AF7A25CF6FEF wds:Q64230111-9B305D9E-A5CF-4FF7-AD35-F4AA0FECC76E wds:Q64230111-A45D6D45-DC18-48DA-8AC0-F2EBB8A5EDE8 wds:Q64230111-A90F85C9-6C98-4C42-8996-FEF53BDD49F9 wds:Q64230111-B09849CE-37E1-426C-A7CC-128694F6F9AD wds:Q64230111-B5840780-F7D2-4D2D-BDC5-0BAA748AB6C6 wds:Q64230111-BF934FC6-5A53-4736-BD70-2641476C2431 wds:Q64230111-C142E208-44AF-4034-A08C-9226207AE991 wds:Q64230111-C33150A5-DC97-4AB7-9983-706FE0E51DB5 wds:Q64230111-C490C9A0-5252-4D89-9BFD-CF09A735E5FC wds:Q64230111-C7EA68FA-4D2E-4983-A0F3-5DCED0BFDD24 wds:Q64230111-DF73BE80-05B8-4461-B2A6-93E0C52A1835 wds:Q64230111-DF9F2FD4-6845-47BE-B2C0-744589BF7927 wds:Q64230111-E2A6F667-6F09-4EFA-8172-D628A5BDC179 wds:Q64230111-E408A674-C030-47E0-AC0A-854EA80575C5 wds:Q64230111-E8D92857-42B4-424F-9151-D1680FCE97A5 wds:Q64230111-ED8901C6-6CA1-4DA9-97B5-627C44A96D0F wds:Q64230111-EF244B52-35A2-4945-BCAB-1E12ECCDAADC wds:Q64230111-F68FFB6A-C780-45B4-B00F-50385EFC49F7 wds:Q64230111-FCDC78CF-77EB-46EE-B550-59954BED89DF wds:Q64230111-FD48E968-4BB6-43D2-855E-61FFD2D294AD
cites work	Novel and therapeutic effect of caffeic acid and caffeic acid phenyl ester on hepatocarcinoma cells: complete regression of hepatoma growth and metastasis by dual mechanism Inhibition of inhibitor of kappaB kinases stimulates hepatic stellate cell apoptosis and accelerated recovery from rat liver fibrosis. Appearance of alpha-smooth-muscle-actin-positive cells in hepatic fibrosis Modern pathogenetic concepts of liver fibrosis suggest stellate cells and TGF-beta as major players and therapeutic targets Smad3 specific inhibitor, naringenin, decreases the expression of extracellular matrix induced by TGF-beta1 in cultured rat hepatic stellate cells Liver fibrosis Smad3 is key to TGF-beta-mediated epithelial-to-mesenchymal transition, fibrosis, tumor suppression and metastasis. Role of the myofibroblast differentiation during liver fibrosis. Role of hepatic stellate cells in fibrogenesis and the reversal of fibrosis Hepatic stellate cells: a target for the treatment of liver fibrosis Emerging insights into Transforming growth factor beta Smad signal in hepatic fibrogenesis. Reversibility of liver fibrosis Immortal hepatic stellate cell lines: useful tools to study hepatic stellate cell biology and function? Liver Fibrosis: From Pathogenesis to Novel Therapies Animal experiment and clinical study of effect of gamma-interferon on hepatic fibrosis. Cell type-specific intervention of transforming growth factor beta/Smad signaling suppresses collagen gene expression and hepatic fibrosis in mice TGF-β signalling and liver disease. The anti-inflammatory effect of kaempferol on early atherosclerosis in high cholesterol fed rabbits Tumor necrosis factor-α promotes cholestasis-induced liver fibrosis in the mouse through tissue inhibitor of metalloproteinase-1 production in hepatic stellate cells Hepatic activation of IKK/NFκB signaling induces liver fibrosis via macrophage-mediated chronic inflammation. The anti-fibrotic effect of green tea with a high catechin content in the galactosamine-injured rat liver. Euonymus alatus prevents the hyperglycemia and hyperlipidemia induced by high-fat diet in ICR mice Expression of the novel extracellular matrix component tenascin in normal and diseased human liver. An immunohistochemical study Protective effects of kaempferol on isoniazid- and rifampicin-induced hepatotoxicity Advance of chemistry and bioactivities of catechin and its analogues Effects of dithiocarb and (+)-catechin against carbon tetrachloride-alcohol-induced liver fibrosis Pivotal Role of TNF-α in the Development and Progression of Nonalcoholic Fatty Liver Disease in a Murine Model. Effect of Cudrania tricuspidata and Kaempferol in Endoplasmic Reticulum Stress-Induced Inflammation and Hepatic Insulin Resistance in HepG2 Cells Antifibrotic effects of green tea on in vitro and in vivo models of liver fibrosis (+)-Catechin attenuates activation of hepatic stellate cells Antiproliferative effect of catechin in GRX cells. Kaempferol nanoparticles achieve strong and selective inhibition of ovarian cancer cell viability Inhibitory effects of Scutellaria barbata D. Don. and Euonymus alatus Sieb. on aromatase activity of human leiomyomal cells. Inhibitory effect of methanol extract of Euonymus alatus on matrix metalloproteinase-9. Euonymus alatus (Thunb.) Sieb induces apoptosis via mitochondrial pathway as prooxidant in human uterine leiomyomal smooth muscle cells Large-scale and effective screening of Korean medicinal plants for inhibitory activity on matrix metalloproteinase-9. Euonymus alatus: A Review on Its Phytochemistry and Antidiabetic Activity Differential regulation of protein kinase C activity by modulating factors and Euonymus alatus (Thunb.) Sieb in human myometrial and uterine leiomyomal smooth muscle cells
author name string	wds:Q64230111-28918FD1-995B-48F8-AEBE-020148E35C8E wds:Q64230111-78AE9EE1-1317-4B76-8F7E-619467C88284 wds:Q64230111-78ED771F-054C-4124-99CC-7C747D9B543F wds:Q64230111-98F1D327-9CE3-4EDB-A9D1-4955B2F47B12 wds:Q64230111-AC94D7FF-DB54-48AD-8D1C-E723722FCC76 wds:Q64230111-CD2F9651-6DB9-469E-BF3E-B7C0A9357BDA
author name string	De-Bin Huang Xing Wan Xiang-Peng Wang Ze-Hua Hu Han-Cheng Huang Ke-Yun Liu
rdfs:label	and its monomers alleviate liver fibrosis both in mice and LX2 cells by blocking TβR1-Smad2/3 and TNF-α-NF-κB pathways (en) and its monomers alleviate liver fibrosis both in mice and LX2 cells by blocking TβR1-Smad2/3 and TNF-α-NF-κB pathways (nl)

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