About: The landscape of d16HER2 splice variant expression across HER2-positive cancers

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About: The landscape of d16HER2 splice variant expression across HER2-positive cancers Goto Sponge NotDistinct Permalink

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scientific article published on 05 March 2019

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rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в березні 2019 (uk) im März 2019 veröffentlichter wissenschaftlicher Artikel (de) artículu científicu espublizáu en marzu de 2019 (ast) scientific article published on 05 March 2019 (en)
publication date	wds:Q64065309-659EC7EA-424E-49CD-8148-92841FCC40CF
publication date	2019-03-05 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q64065309-FB5CA754-F7A9-42DF-9798-FA4E38BFFDD4
language of work or name	English
cites work	wds:Q64065309-008D2DCD-E452-4DB9-BC8B-7FAC7456AFAD wds:Q64065309-04ECFC37-3B19-4B31-A073-CDA3C6F40B33 wds:Q64065309-0501C191-F204-4258-A728-5D078F9D1370 wds:Q64065309-07D038DC-2568-4278-B6CF-BBCB2366422F wds:Q64065309-0C0ADF5A-4417-4566-BF7C-EEE1B686DA53 wds:Q64065309-29D6EB8F-6A76-4318-95D8-EB7E5FB161F4 wds:Q64065309-48B6531B-1C58-49DC-AE6F-20B6FC14D7A9 wds:Q64065309-549D553E-7043-455B-A13C-A616DB3BE0A3 wds:Q64065309-577C7488-7AED-48A7-9D3A-2578B26C4FC6 wds:Q64065309-68454E70-0AD8-491A-A5B2-736D0C89D280 wds:Q64065309-69627775-BC15-413B-A37B-F5DDE3D5B74F wds:Q64065309-69C1DB8B-76F7-4967-A8C7-6AE9DE71917B wds:Q64065309-6C67FAA3-6C9E-4276-8340-1432773BD8A1 wds:Q64065309-6F9CA3C2-66D0-42CE-9881-5B3F6F4DAA93 wds:Q64065309-7078C0E0-4197-405B-9403-A1DA11FA2CFA wds:Q64065309-785FF07B-70DA-4533-9586-36EC0117EDE7 wds:Q64065309-801789B1-D502-42FB-B3FB-5B7907D11C2F wds:Q64065309-8661A08D-0D4C-4EDD-851E-52230DB04063 wds:Q64065309-94CABC69-5DBD-4BAF-AC52-FDC9B28076B8 wds:Q64065309-9BD26742-A9C1-4E54-8D72-6C856570FEE6 wds:Q64065309-A1F90AED-AC6A-47E6-AE85-7D20D02DB497 wds:Q64065309-A7C3D6F8-75AC-4BE8-8BAC-DF17BBD7B7EB wds:Q64065309-AFDE4AC0-80F2-404B-A241-7C3AABC951F6 wds:Q64065309-B672202E-096D-4772-B016-1A833B3A7C87 wds:Q64065309-BD5CCDB5-0E7A-41E2-9908-CE7B69283D7C wds:Q64065309-BDB66C4D-BDF8-482A-8B03-F7770E352943 wds:Q64065309-BEBC0A1D-FD3A-4FFF-895C-DE0EEE36AAC6 wds:Q64065309-C5D486E4-4B36-4290-9E87-601E0B145F65 wds:Q64065309-CFCD0F62-220C-45DE-A616-25D765CBC9BA wds:Q64065309-D39F6217-5A79-4EBF-A8C8-685A1CC5AD04 wds:Q64065309-DFE17D8B-A481-40FF-8AE5-D83A8C866835 wds:Q64065309-EC15C6FB-E71D-4847-A433-B792F1B88CAD wds:Q64065309-F71604B5-BDC8-4589-809C-09F6DFB8A4D5 wds:Q64065309-F9EEA9B9-FFED-4BF7-A907-B4886C7CB733 wds:Q64065309-FEB43136-ECBD-4293-AFB1-12A0D685C988 wds:Q64065309-FF9ACB88-0FC3-4C85-9EA2-4B10FE03F409
cites work	RNAscope: a novel in situ RNA analysis platform for formalin-fixed, paraffin-embedded tissues Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial Neoplastic and stromal cells contribute to an extracellular matrix gene expression profile defining a breast cancer subtype likely to progress Lapatinib plus paclitaxel versus paclitaxel alone in the second-line treatment of HER2-amplified advanced gastric cancer in Asian populations: TyTAN--a randomized, phase III study A molecularly annotated platform of patient-derived xenografts ("xenopatients") identifies HER2 as an effective therapeutic target in cetuximab-resistant colorectal cancer HER2 as a target for breast cancer therapy. Alternative splicing in cancer: implications for biology and therapy Pathobiological implications of the d16HER2 splice variant for stemness and aggressiveness of HER2-positive breast cancer The human splice variant Δ16HER2 induces rapid tumor onset in a reporter transgenic mouse. The ErbB2ΔEx16 splice variant is a major oncogenic driver in breast cancer that promotes a pro-metastatic tumor microenvironment Clinical Significance of HER-2 Splice Variants in Breast Cancer Progression and Drug Resistance. Truncated HER2: implications for HER2-targeted therapeutics Activated d16HER2 homodimers and SRC kinase mediate optimal efficacy for trastuzumab An oncogenic isoform of HER2 associated with locally disseminated breast cancer and trastuzumab resistance Role of exon-16-deleted HER2 in breast carcinomas A novel splice variant of HER2 with increased transformation activity Mammary tumor formation and metastasis evoked by a HER2 splice variant Activating mutations in HER2: neu opportunities and neu challenges Recommendations for human epidermal growth factor receptor 2 testing in breast cancer: American Society of Clinical Oncology/College of American Pathologists clinical practice guideline update Efficacy and safety of neoadjuvant pertuzumab and trastuzumab in women with locally advanced, inflammatory, or early HER2-positive breast cancer (NeoSphere): a randomised multicentre, open-label, phase 2 trial Pertuzumab plus trastuzumab plus docetaxel for metastatic breast cancer Trastuzumab (herceptin) targets gastric cancer stem cells characterized by CD90 phenotype. Trastuzumab emtansine versus taxane use for previously treated HER2-positive locally advanced or metastatic gastric or gastro-oesophageal junction adenocarcinoma (GATSBY): an international randomised, open-label, adaptive, phase 2/3 study Assessment of a HER2 scoring system for colorectal cancer: results from a validation study HER2 loss in HER2-positive gastric or gastroesophageal cancer after trastuzumab therapy: Implication for further clinical research. Dual-targeted therapy with trastuzumab and lapatinib in treatment-refractory, KRAS codon 12/13 wild-type, HER2-positive metastatic colorectal cancer (HERACLES): a proof-of-concept, multicentre, open-label, phase 2 trial HER2/neu testing in gastric cancer by immunohistochemistry: assessment of interlaboratory variation Genetic Predictors of Response to Systemic Therapy in Esophagogastric Cancer. Radiologic and Genomic Evolution of Individual Metastases during HER2 Blockade in Colorectal Cancer Biomarkers of Primary Resistance to Trastuzumab in HER2-Positive Metastatic Gastric Cancer Patients: the AMNESIA Case-Control Study. Current and future perspectives of liquid biopsies in genomics-driven oncology Trastuzumab deruxtecan (DS-8201a) in subjects with HER2-expressing solid tumors: Long-term results of a large phase 1 study with multiple expansion cohorts Liquid biopsy in ovarian cancer: the potential of circulating miRNAs and exosomes Intratumor lactate levels reflect HER2 addiction status in HER2-positive breast cancer HER2 Testing and Clinical Decision Making in Gastroesophageal Adenocarcinoma: Guideline From the College of American Pathologists, American Society for Clinical Pathology, and American Society of Clinical Oncology. Assessing HER2 testing quality in breast cancer: variables that influence HER2 positivity rate from a large, multicenter, observational study in Germany
author name string	wds:Q64065309-03F14A00-5EAC-4399-8BD0-731C6D4FFEBE wds:Q64065309-09B69433-72CC-4FFC-B486-2A921986A44E wds:Q64065309-1079DF08-14C7-49E2-9C6B-E2B7DAFACE63 wds:Q64065309-146183B9-2D54-4AF4-AC98-E6C1CD83402E wds:Q64065309-1AA0105A-2C94-4232-8CB1-1001C2F2AB85 wds:Q64065309-2B03B917-CC58-4510-943F-8C2E8C6AC0DD wds:Q64065309-85774FD0-2094-4608-8A6D-3EF441733476 wds:Q64065309-986ED1C2-198B-4E55-9D0A-7150886834DA wds:Q64065309-C41EE623-3C93-4676-8F42-EE2257FAF54A wds:Q64065309-FED80FD6-4DB4-4435-8637-52C6999F0B46
author name string	Giancarlo Pruneri Filippo de Braud Chiara Cremolini Maria Di Bartolomeo Elena Fasano Massimo Di Nicola Chiara Costanza Volpi Maria Antista

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