About: Exploiting the DNA Repair Defect in BRCA Mutant Cells in the Design of New Therapeutic Strategies for Cancer

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scientific article published on 01 January 2005

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) im Jahr 2005 veröffentlichter wissenschaftlicher Artikel (de) article scientifique (publié 2005) (fr) 2005 թվականին հրատարակված գիտական հոդված (hy) наукова стаття, опублікована в січні 2005 (uk) artículu científicu espublizáu en xineru de 2005 (ast) artikull shkencor i botuar më 01 janar 2005 (sq) scientific article published on 01 January 2005 (en)
publication date	wds:Q63362916-79198596-F267-4AB1-8E3F-ACFCA19F7E25
publication date	2005-01-01 00:00:00Z (xsd:dateTime)
cites work	wds:Q63362916-374C57E9-CF7F-41E3-BBE1-902DF144C5C4
cites work	Association of BRCA1 with the hRad50-hMre11-p95 complex and the DNA damage response
author name string	wds:Q63362916-17507F90-1004-4915-A9AF-C5DA3494BF26 wds:Q63362916-37F85D07-9649-4A09-B2D5-BAFBD6FFEDA2 wds:Q63362916-47712E1B-9B29-4A77-9D2E-4CAFA51F9C36 wds:Q63362916-567422DC-2E5A-4134-A98E-B14C3F7B3A45 wds:Q63362916-58C611E0-13FE-404A-A950-812F206ECBBE wds:Q63362916-6ED766D9-F6F9-4B7D-86AF-8EEBDB324CF3 wds:Q63362916-9424B900-3726-4644-91FB-8329063952B4 wds:Q63362916-DC0C2B42-8D0A-4391-9519-234FA51DB715
author name string	A Ashworth C J Lord N Turner N M Martin N McCabe G C M Smith H Farmer A N J Tutt
rdfs:label	Exploiting the DNA Repair Defect in BRCA Mutant Cells in the Design of New Therapeutic Strategies for Cancer (en) Exploiting the DNA Repair Defect in BRCA Mutant Cells in the Design of New Therapeutic Strategies for Cancer (nl) Exploiting the DNA Repair Defect in BRCA Mutant Cells in the Design of New Therapeutic Strategies for Cancer (sq)
skos:prefLabel	Exploiting the DNA Repair Defect in BRCA Mutant Cells in the Design of New Therapeutic Strategies for Cancer (en) Exploiting the DNA Repair Defect in BRCA Mutant Cells in the Design of New Therapeutic Strategies for Cancer (nl) Exploiting the DNA Repair Defect in BRCA Mutant Cells in the Design of New Therapeutic Strategies for Cancer (sq)
name	Exploiting the DNA Repair Defect in BRCA Mutant Cells in the Design of New Therapeutic Strategies for Cancer (en) Exploiting the DNA Repair Defect in BRCA Mutant Cells in the Design of New Therapeutic Strategies for Cancer (nl) Exploiting the DNA Repair Defect in BRCA Mutant Cells in the Design of New Therapeutic Strategies for Cancer (sq)
author	wds:Q63362916-F7D6CE35-656B-4E3A-BBBF-53441C4B8B8C
author	Stephen P Jackson
title	wds:Q63362916-B931CC29-7B37-4DE6-979B-BC7C27562E87
title	Exploiting the DNA repair defect in BRCA mutant cells in the design of new therapeutic strategies for cancer (en)
page(s)	wds:Q63362916-8B5B2301-6DA2-4606-AD2D-840CE8A85A56
page(s)	139-148
instance of	wds:Q63362916-F8EFC3D3-A8C1-41F0-B271-49392EB4161F
instance of	scholarly article
PubMed ID	wds:Q63362916-8C1EE935-01B4-4E2E-A1D9-8030F77EBADA
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/16869747
PubMed ID	16869747
published in	wds:Q63362916-59B67AF4-A39F-4B71-A18B-09C2CA37ACEA
published in	Cold Spring Harbor Symposia on Quantitative Biology
issue	wds:Q63362916-849AADA1-3EC1-44EC-A013-B31A76557BD7
volume	wds:Q63362916-A6A92F71-0BC8-4208-9A86-78C0537B4682
issue	0
volume	70
DOI	wds:Q63362916-C64EE2DE-62DE-4577-9185-5999D8D157E6
DOI	http://dx.doi.org/10.1101/SQB.2005.70.012
DOI	10.1101/SQB.2005.70.012
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q63362916
is cites work of	Clinical relevance of the triple-negative breast cancer concept: genetic basis and clinical utility of the concept BRCAness revisited Targeted therapy in ovarian cancer Critical molecular abnormalities in high-grade serous carcinoma of the ovary Molecular abnormalities in ovarian cancer subtypes other than high-grade serous carcinoma Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: a proof-of-concept trial Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer: a proof-of-concept trial Synthetic lethal targeting of PTEN mutant cells with PARP inhibitors Resistance to therapy caused by intragenic deletion in BRCA2 Secondary mutations as a mechanism of cisplatin resistance in BRCA2-mutated cancers Synthetic lethal approaches to breast cancer therapy Triple-negative breast cancer: therapeutic options Targeting the DNA repair pathway in Ewing sarcoma PARP inhibitors in the management of breast cancer: current data and future prospects Ovarian carcinomas: five distinct diseases with different origins, genetic alterations, and clinicopathological features Targeting Tankyrase 1 as a therapeutic strategy for BRCA-associated cancer. Poly (ADP-ribose) polymerase inhibitors: on the horizon of tailored and personalized therapies for epithelial ovarian cancer Beyond chemotherapy: targeted therapies in ovarian cancer Overcoming drug resistance in pancreatic cancer. Exploiting synthetic lethal interactions for targeted cancer therapy Impact of delay to cryopreservation on RNA integrity and genome-wide expression profiles in resected tumor samples International Agency for Research on Cancer workshop on 'Expression array analyses in breast cancer taxonomy' Emerging Roles of SIRT1 in Cancer Drug Resistance Emergence of rationally designed therapeutic strategies for breast cancer targeting DNA repair mechanisms A DNA repair pathway-focused score for prediction of outcomes in ovarian cancer treated with platinum-based chemotherapy Predicting drug responsiveness in human cancers using genetically engineered mice. Hereditary breast cancer: pathobiology, clinical translation, and potential for targeted cancer therapeutics Triple-negative breast cancers: an updated review on treatment options The clinical value of aberrant epigenetic changes of DNA damage repair genes in human cancer Macrocyclized Extended Peptides: Inhibiting the Substrate-Recognition Domain of Tankyrase. Breast cancer in the personal genomics era DNA Damage Signalling and Repair Inhibitors: The Long-Sought-After Achilles' Heel of Cancer A current review of targeted therapeutics for ovarian cancer Overall survival and clinical characteristics of pancreatic cancer in BRCA mutation carriers Making the best of PARP inhibitors in ovarian cancer Anti-tumor activity of olaparib, a poly (ADP-ribose) polymerase (PARP) inhibitor, in cultured endometrial carcinoma cells Demystifying basal-like breast carcinomas Clinicopathological values of NBS1 and DNA damage response genes in epithelial ovarian cancers Technology as a force for improved diagnosis and treatment of breast disease The Emerging Role of PARP Inhibitors in the Treatment of Epithelial Ovarian Cancer Inhibition of PARP1-dependent end-joining contributes to Olaparib-mediated radiosensitization in tumor cells

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