About: Brian Huntly

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An Entity of Type : wikibase:Item, within Data Space : wikidata.demo.openlinksw.com associated with source document(s)

researcher ORCID ID = 0000-0003-0312-161X

Attributes	Values
rdf:type	Item
description	forskare (sv) ikertzailea (eu) 연구원 (ko) araştırmacı (tr) वैज्ञानिक (hi) изилдөөчү (ky) 研究者 (zh) onderzoeker (nl) researcher ORCID ID = 0000-0003-0312-161X (en)
rdfs:label	Brian Huntly (en) Brian Huntly (es) Brian Huntly (nl) Brian Huntly (ast)
skos:prefLabel	Brian Huntly (en) Brian Huntly (es) Brian Huntly (nl) Brian Huntly (ast)
name	Brian Huntly (en) Brian Huntly (es) Brian Huntly (nl) Brian Huntly (ast)
given name	wds:Q60992471-1E190E40-84A7-48CD-BD38-BBDCEF83C33F
given name	Brian
instance of	wds:Q60992471-586CAB05-0B92-4B5B-8D71-A20EF165A1E7
instance of	Homo sapiens
occupation	wds:Q60992471-90FC2B99-512A-4246-80BE-EF72AA9C152F
employer	wds:Q60992471-021BCC54-D225-4EC8-9FB1-73306B028D2D wds:Q60992471-07993851-CEF8-4550-888E-B95AE3D03400 wds:Q60992471-28E8A6AA-92D6-4CB0-A46A-CD91BB822D29 wds:Q60992471-2EE63B05-39FC-4A51-AFF6-073BA757E9BE wds:Q60992471-3CC05B18-6B07-44D1-94D1-C2A6CAF9B9C6 wds:Q60992471-5B5582DE-D543-41DA-88C4-707FB6C81E3D wds:Q60992471-6A693A79-EBF1-4041-BF10-F1D9EB4C4036 wds:Q60992471-74F3BE8F-99A0-4FAE-89FC-146D7658DD89 wds:Q60992471-7F8F0C5C-A9CE-46BC-B556-8889B8EF6B4F wds:Q60992471-E20F6048-555C-47C6-8940-864762DA705E
occupation	researcher
employer	Victoria Hospital, Kirkcaldy Cambridge University Hospitals NHS Foundation Trust John Ffowcs Williams Ninewells Hospital Brigham and Women's Hospital
ORCID iD	wds:Q60992471-E03F9F59-C13F-40EA-83E1-FB8F4EF8D6F8
ORCID iD	https://orcid.org/0000-0003-0312-161X
ORCID iD	0000-0003-0312-161X
Gateway to Research person ID	wds:Q60992471-DC664513-432A-4442-B64E-6273627B8C4F
Gateway to Research person ID	748DF1D8-D39E-4047-B5CC-0D6864CA4C1A
ResearcherID	wds:Q60992471-FEEAFBC6-80F9-4637-8427-A9CF7E091566
ResearcherID	E-6725-2014
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q60992471
is author of	Mutation and methylation analysis of the transforming growth factor beta receptor II gene in polycythaemia vera HOX-mediated LMO2 expression in embryonic mesoderm is recapitulated in acute leukaemias. Blasts from the past: new lessons in stem cell biology from chronic myelogenous leukemia FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress Myeloproliferative disorders Network properties derived from deep sequencing of human B-cell receptor repertoires delineate B-cell populations Somatic drivers of B-ALL in a model of ETV6-RUNX1; Pax5(+/-) leukemia Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis Targeting epigenetic readers in cancer. Leukaemia stem cells and the evolution of cancer-stem-cell research. Clinical utility of routine MPL exon 10 analysis in the diagnosis of essential thrombocythaemia and primary myelofibrosis. Requirement for CDK6 in MLL-rearranged acute myeloid leukemia Somatic CALR mutations in myeloproliferative neoplasms with nonmutated JAK2 Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia The JAK2V617F activating mutation occurs in chronic myelomonocytic leukemia and acute myeloid leukemia, but not in acute lymphoblastic leukemia or chronic lymphocytic leukemia MOZ-TIF2, but not BCR-ABL, confers properties of leukemic stem cells to committed murine hematopoietic progenitors. Recurrent mutations, including NPM1c, activate a BRD4-dependent core transcriptional program in acute myeloid leukemia Does isochromosome 7q mandate bone marrow transplant in children with Shwachman-Diamond syndrome? Large deletions at the t(9;22) breakpoint are common and may identify a poor-prognosis subgroup of patients with chronic myeloid leukemia Constitutively activated FGFR3 mutants signal through PLCgamma-dependent and -independent pathways for hematopoietic transformation. Cancer stem cell definitions and terminology: the devil is in the details. Cancer biology: summing up cancer stem cells. Visual information processing during controlled hypoglycaemia in humans. Leukemia stem cells in acute myeloid leukemia. Molecular landscape of acute myeloid leukemia in younger adults and its clinical relevance Imatinib improves but may not fully reverse the poor prognosis of patients with CML with derivative chromosome 9 deletions. Survival implications of molecular heterogeneity in variant Philadelphia-positive chronic myeloid leukaemia Variant Philadelphia translocations in chronic myeloid leukaemia can mimic typical blast crisis chromosome abnormalities or classic t(9;22): a report of two cases Recent advances in acute myeloid leukemia stem cell biology A novel signalling screen demonstrates that CALR mutations activate essential MAPK signalling and facilitate megakaryocyte differentiation. Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition FLT3 internal tandem duplication mutations induce myeloproliferative or lymphoid disease in a transgenic mouse model. BET bromodomain inhibitors in leukemia. Double jeopardy from a single translocation: deletions of the derivative chromosome 9 in chronic myeloid leukemia. Derivative chromosome 9 deletions in chronic myeloid leukemia: poor prognosis is not associated with loss of ABL-BCR expression, elevated BCR-ABL levels, or karyotypic instability. Modeling the evolution of ETV6-RUNX1-induced B-cell precursor acute lymphoblastic leukemia in mice. A novel mouse model identifies cooperating mutations and therapeutic targets critical for chronic myeloid leukemia progression Chromosome 20 deletions in myeloid malignancies: reduction of the common deleted region, generation of a PAC/BAC contig and identification of candidate genes HOX gene regulation in acute myeloid leukemia: CDX marks the spot? The epigenetic regulators CBP and p300 facilitate leukemogenesis and represent therapeutic targets in acute myeloid leukemia. Mll-AF4 Confers Enhanced Self-Renewal and Lymphoid Potential during a Restricted Window in Development A Polycythemia Vera Updated: Diagnosis, Pathobiology, and Treatment. A CRISPR Dropout Screen Identifies Genetic Vulnerabilities and Therapeutic Targets in Acute Myeloid Leukemia. The transcriptional coactivator Cbp regulates self-renewal and differentiation in adult hematopoietic stem cells. Functional interdependence of BRD4 and DOT1L in MLL leukemia The antiproliferative activity of kinase inhibitors in chronic myeloid leukemia cells is mediated by FOXO transcription factors Targeting cancer stem cells. Genome-wide analysis of transcriptional reprogramming in mouse models of acute myeloid leukaemia Activity of a heptad of transcription factors is associated with stem cell programs and clinical outcome in acute myeloid leukemia

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