About: APIM-Mediated REV3L⁻PCNA Interaction Important for Error Free TLS Over UV-Induced DNA Lesions in Human Cells

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About: APIM-Mediated REV3L⁻PCNA Interaction Important for Error Free TLS Over UV-Induced DNA Lesions in Human Cells Goto Sponge NotDistinct Permalink

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journal article from 'International Journal of Molecular Sciences' published in 2019

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в грудні 2018 (uk) article scientifique publié en 2018 (fr) im Dezember 2018 veröffentlichter wissenschaftlicher Artikel (de) journal article from 'International Journal of Molecular Sciences' published in 2019 (en)
publication date	wds:Q60927734-949FF284-85B2-4465-840C-BC3F80A7731F wds:Q60927734-C6B2AFBD-048D-40C0-8E8C-42A26B44BF94
publication date	2018-12-28 00:00:00Z (xsd:dateTime) 2019-01-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q60927734-68C51B3E-F819-4FF3-9DE3-DEF80CC494E1
language of work or name	English
cites work	wds:Q60927734-160C02DC-8882-4D08-AD75-DA7178BA5D7E wds:Q60927734-1A561F07-FA44-4400-8577-45F1A07FC230 wds:Q60927734-1A7D770C-9798-4F3A-8ACE-9E9BD207A5A2 wds:Q60927734-1E9A4119-5D14-4DEB-AB8C-D2D972ACBFF3 wds:Q60927734-2548B8A4-F3DC-4156-9263-32E360344775 wds:Q60927734-2609A4DB-E5E2-40BB-A478-E4DAB38DCBEE wds:Q60927734-28069259-D955-4812-9049-92F66592C4DB wds:Q60927734-3062D588-9430-4806-87B5-B690DEBD8B54 wds:Q60927734-36D2C569-1D06-4A06-9C09-2C0A331F08B4 wds:Q60927734-3EC46AEE-635C-4C99-9F0A-5C1F4378F5AE wds:Q60927734-3F2C417A-8A19-4AD6-BF40-E2473B38AC88 wds:Q60927734-41164533-780B-4A2C-85FD-E450CC8FF4D5 wds:Q60927734-42D1FE14-7F9F-490D-9242-81A3E898F287 wds:Q60927734-47D27F00-FC54-4E19-AE73-79CFD454DCCB wds:Q60927734-48126B65-9E21-43B2-8DD9-416C2BF9C7A2 wds:Q60927734-4BF9FF28-120D-46E8-8485-DD5F0FFE05BB wds:Q60927734-50D8CF4B-24EA-4E50-B01A-EDB90B020F77 wds:Q60927734-5178950F-5539-480F-B04E-3B7FE825EA10 wds:Q60927734-5568048B-61B4-4420-91CC-83BD2BD3A8A0 wds:Q60927734-5A512CF1-B470-4815-8020-FAB58FEFD34C wds:Q60927734-6B859E5B-098D-4C72-8469-67E8A90D3E19 wds:Q60927734-6E529987-B26A-4124-B64D-225AF68D119F wds:Q60927734-72040E5B-D165-4CB8-BAE6-8A0D7061C30A wds:Q60927734-88BF8CDB-C2AD-42BC-B0EE-B0A70D1EA4FF wds:Q60927734-99680157-BE5D-41C6-A8D1-0F8D0154A1DA wds:Q60927734-9BAD1974-1B99-4A58-B078-BB893D18B64F wds:Q60927734-A1AABE10-E8AF-4D62-814D-04BBF4B08EDB wds:Q60927734-A363A5AF-0CBC-4D61-977C-0121B7E95D61 wds:Q60927734-CA59C427-BED9-469A-A1DF-82FF26B0E7F3 wds:Q60927734-D86A829E-824B-4AAE-90EC-88762A85C08B wds:Q60927734-DCE8F8C7-174D-43E9-A963-F8CEA48EE76E wds:Q60927734-E333A152-C91B-4E95-B024-50552C3A11A2 wds:Q60927734-E7047E70-3B0B-46A4-9E64-0F97B491090D wds:Q60927734-ED7A32F9-3D4C-4DBE-8B2D-78BF23FCD094 wds:Q60927734-EEA961D7-AD15-4E05-A475-48CD902F849A wds:Q60927734-EF6EFD80-4280-4E2A-92A0-412D26226733 wds:Q60927734-F94CC09E-ABEC-4D50-823D-91BE0165037B
cites work	Direct interaction between XRCC1 and UNG2 facilitates rapid repair of uracil in DNA by XRCC1 complexes Human REV3 DNA Polymerase Zeta Localizes to Mitochondria and Protects the Mitochondrial Genome Error-free replicative bypass of (6-4) photoproducts by DNA polymerase zeta in mouse and human cells Identification of a novel, widespread, and functionally important PCNA-binding motif Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue in the central conserved region Human and bacterial oxidative demethylases repair alkylation damage in both RNA and DNA Regulation of translesion synthesis DNA polymerase eta by monoubiquitination Mass Spectrometric Sequencing of Proteins from Silver-Stained Polyacrylamide Gels Nucleotide excision repair is associated with the replisome and its efficiency depends on a direct interaction between XPA and PCNA Regulation of PCNA-protein interactions for genome stability Mediation of proliferating cell nuclear antigen (PCNA)-dependent DNA replication through a conserved p21(Cip1)-like PCNA-binding motif present in the third subunit of human DNA polymerase delta Structural and thermodynamic analysis of human PCNA with peptides derived from DNA polymerase-delta p66 subunit and flap endonuclease-1. Human Pol ζ purified with accessory subunits is active in translesion DNA synthesis and complements Pol η in cisplatin bypass The helicase FBH1 is tightly regulated by PCNA via CRL4(Cdt2)-mediated proteolysis in human cells Targeting proliferating cell nuclear antigen and its protein interactions induces apoptosis in multiple myeloma cells REV1 and polymerase ζ facilitate homologous recombination repair Novel evidences for a tumor suppressor role of Rev3, the catalytic subunit of Pol zeta SHPRH and HLTF act in a damage-specific manner to coordinate different forms of postreplication repair and prevent mutagenesis Involvement of mouse Rev3 in tolerance of endogenous and exogenous DNA damage A four-subunit DNA polymerase ζ complex containing Pol δ accessory subunits is essential for PCNA-mediated mutagenesis PCNA-interacting peptides reduce Akt phosphorylation and TLR-mediated cytokine secretion suggesting a role of PCNA in cellular signaling The interaction between ALKBH2 DNA repair enzyme and PCNA is direct, mediated by the hydrophobic pocket of PCNA and perturbed in naturally-occurring ALKBH2 variants Interaction between the Rev1 C-Terminal Domain and the PolD3 Subunit of Polζ Suggests a Mechanism of Polymerase Exchange upon Rev1/Polζ-Dependent Translesion Synthesis Molecular cloning, expression and chromosomal localisation of the mouse Rev3l gene, encoding the catalytic subunit of polymerase zeta. The role of DNA polymerase ζ in translesion synthesis across bulky DNA adducts and cross-links in human cells Monitoring of the spatial and temporal dynamics of BER/SSBR pathway proteins, including MYH, UNG2, MPG, NTH1 and NEIL1-3, during DNA replication. Rad18-dependent SUMOylation of human specialized DNA polymerase eta is required to prevent under-replicated DNA. Structural insights into the function of ZRANB3 in replication stress response. Forging Ahead through Darkness: PCNA, Still the Principal Conductor at the Replication Fork Translesion Synthesis: Insights into the Selection and Switching of DNA Polymerases. Maneuvers on PCNA Rings during DNA Replication and Repair Rev1 promotes replication through UV lesions in conjunction with DNA polymerases η, ι, and κ but not DNA polymerase ζ Increased Anticancer Efficacy of Intravesical Mitomycin C Therapy when Combined with a PCNA Targeting Peptide APIM-peptide targeting PCNA improves the efficacy of docetaxel treatment in the TRAMP mouse model of prostate cancer. The role of PCNA as a scaffold protein in cellular signaling is functionally conserved between yeast and humans. "Two hits - one stone"; increased efficacy of cisplatin-based therapies by targeting PCNA's role in both DNA repair and cellular signaling Structure of proliferating cell nuclear antigen (PCNA) bound to an APIM peptide reveals the universality of PCNA interaction
author name string	wds:Q60927734-15BF102F-5FCB-4496-A1A3-9F7137B76BA9 wds:Q60927734-383DB783-DB1D-4843-8BFE-76AD5A920BBF wds:Q60927734-685074DF-3960-42F8-91DF-A6990BEEAAAF wds:Q60927734-6FF924FE-52FF-4ABF-8184-0C30051F6929 wds:Q60927734-9C9A0C16-2B1F-4A1A-90B3-32A08174588C wds:Q60927734-A4E04DE5-C753-4006-8262-478E3CC1391C wds:Q60927734-AC163228-119C-41D6-85E9-6E00BB8BAF0D
author name string	Rebekka Müller Mareike Seelinger Anala Nepal Aina Nedal Karine Øian Bjørås Rønnaug Steen Kolve Synnøve Brandt Ræder

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