About: DNA damage response and cellular senescence in tissues of aging mice

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About: DNA damage response and cellular senescence in tissues of aging mice Goto Sponge NotDistinct Permalink

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scientific article published on 09 April 2009

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) article scientifique publié en 2009 (fr) наукова стаття, опублікована в травні 2009 (uk) im Mai 2009 veröffentlichter wissenschaftlicher Artikel (de) scientific article published on 09 April 2009 (en) artículu científicu espublizáu n'abril de 2009 (ast)
publication date	wds:Q60284563-268CD270-CDCA-41DF-AEAB-57F578F513D5
publication date	2009-04-09 00:00:00Z (xsd:dateTime)
cites work	wds:Q60284563-044CFA81-485F-4716-B784-D3725812BACC wds:Q60284563-8E618777-A8EC-4DDD-B619-66F1E584343C
cites work	Extension of life-span by introduction of telomerase into normal human cells THE LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS
author name string	wds:Q60284563-6169E1C5-EFAD-48D0-8155-8D2B90AFEBAF wds:Q60284563-75115CBB-36A3-42FC-BEA8-779C2BAF71D0
author name string	Chunfang Wang Mandy Maddick
rdfs:label	DNA damage response and cellular senescence in tissues of aging mice (en) DNA damage response and cellular senescence in tissues of aging mice (nl)
skos:prefLabel	DNA damage response and cellular senescence in tissues of aging mice (en) DNA damage response and cellular senescence in tissues of aging mice (nl)
name	DNA damage response and cellular senescence in tissues of aging mice (en) DNA damage response and cellular senescence in tissues of aging mice (nl)
author	wds:Q60284563-56AB4B4B-314A-407C-8ED7-10A042CCE0E7 wds:Q60284563-625905B7-DEFD-4742-930B-8CAC24B2DE23 wds:Q60284563-DC1EAFED-0F52-4754-8BC8-AB4EB4663E7E wds:Q60284563-E2B6E973-3D79-4780-9726-1680F84CE721
author	Thomas von Zglinicki Diana Jurk Glyn Nelson Carmen M Martin-Ruiz
title	wds:Q60284563-43D1961E-67C9-404D-84F1-B2A499863725
title	DNA damage response and cellular senescence in tissues of aging mice (en)
page(s)	wds:Q60284563-B1A662E4-24A6-49A9-B6E7-4494D9F45EAD
page(s)	311-323
instance of	wds:Q60284563-CE7244D4-5E07-41CE-A893-56134051B022
instance of	scholarly article
main subject	wds:Q60284563-D1C4F69F-29C0-4A88-A821-E487B7D89270
main subject	cellular senescence
PubMed ID	wds:Q60284563-F9927085-F53E-40C3-8451-49E74005C7A1
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/19627270
PubMed ID	19627270
published in	wds:Q60284563-0E562011-5311-4E7F-9AAC-3A3C0C4DCC7A
published in	Aging Cell
issue	wds:Q60284563-C923626F-A872-4344-B154-5DE0AA54F88F
volume	wds:Q60284563-2D099A74-BAD5-4BFC-9E9A-EB91A078A0A7
issue	3
volume	8
DOI	wds:Q60284563-983A92FF-DC8D-4A85-A325-C6D58301D2DF
DOI	http://dx.doi.org/10.1111/J.1474-9726.2009.00481.X
DOI	10.1111/J.1474-9726.2009.00481.X
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q60284563
is cites work of	Four faces of cellular senescence. Aging, cellular senescence, and cancer The p53 network: cellular and systemic DNA damage responses in aging and cancer Impaired antioxidant defence and accumulation of oxidative stress in caspase-2-deficient mice DNA-SCARS: distinct nuclear structures that sustain damage-induced senescence growth arrest and inflammatory cytokine secretion Somatic expansion in mouse and human carriers of fragile X premutation alleles Cholangiocyte senescence by way of N-ras activation is a characteristic of primary sclerosing cholangitis How ageing processes influence cancer Telomeres are favoured targets of a persistent DNA damage response in ageing and stress-induced senescence. The hallmarks of aging Cellular Senescence as the Causal Nexus of Aging Chronic inflammation induces telomere dysfunction and accelerates ageing in mice. Controlled induction of DNA double-strand breaks in the mouse liver induces features of tissue ageing Loss of Nfkb1 leads to early onset aging Adult-onset, short-term dietary restriction reduces cell senescence in mice. Feedback between p21 and reactive oxygen production is necessary for cell senescence Mitochondrial oxidative stress caused by Sod2 deficiency promotes cellular senescence and aging phenotypes in the skin Dynamic modelling of pathways to cellular senescence reveals strategies for targeted interventions Stem cell ageing and non-random chromosome segregation. microRNA expression patterns reveal differential expression of target genes with age. Low abundance of the matrix arm of complex I in mitochondria predicts longevity in mice p53-dependent release of Alarmin HMGB1 is a central mediator of senescent phenotypes Empowering adult stem cells for myocardial regeneration Aging and radiation: bad companions Age-related gene response of human corneal endothelium to oxidative stress and DNA damage. Regulation of cellular senescence by the essential caveolar component PTRF/Cavin-1. Manifestations and mechanisms of stem cell aging. Do telomeres adapt to physiological stress? Exploring the effect of exercise on telomere length and telomere-related proteins Telomeres, oxidative stress and inflammatory factors: partners in cellular senescence? Fat tissue, aging, and cellular senescence Aging on a different scale--chronological versus pathology-related aging GSK-3α is a central regulator of age-related pathologies in mice Do DNA Double-Strand Breaks Drive Aging? Ionizing radiation-induced long-term expression of senescence markers in mice is independent of p53 and immune status Lgr5 intestinal stem cells have high telomerase activity and randomly segregate their chromosomes Aging of the mammalian gastrointestinal tract: a complex organ system A senescent cell bystander effect: senescence-induced senescence Postmitotic neurons develop a p21-dependent senescence-like phenotype driven by a DNA damage response Accumulation of DNA damage in hematopoietic stem and progenitor cells during human aging Wnt/β-catenin signaling induces the aging of mesenchymal stem cells through the DNA damage response and the p53/p21 pathway A comparison of replicative senescence and doxorubicin-induced premature senescence of vascular smooth muscle cells isolated from human aorta Irreparable telomeric DNA damage and persistent DDR signalling as a shared causative mechanism of cellular senescence and ageing. Age-associated increase in heterochromatic marks in murine and primate tissues Transposable elements become active and mobile in the genomes of aging mammalian somatic tissues How to measure RNA expression in rare senescent cells expressing any specific protein such as p16Ink4a Cellular senescence: putting the paradoxes in perspective Physiological and pathological consequences of cellular senescence. Cellular senescence: from growth arrest to immunogenic conversion

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