About: Reduced satiating effect of d -fenfluramine in serotonin 5-HT 2C receptor mutant mice

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scientific article published on 01 April 1999

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована у квітні 1999 (uk) article scientifique publié en 1999 (fr) im April 1999 veröffentlichter wissenschaftlicher Artikel (de) artículu científicu espublizáu n'abril de 1999 (ast) scientific article published on 01 April 1999 (en)
publication date	wds:Q60054745-9E4CD8AB-F989-403B-8311-42F74E36617F
publication date	1999-04-01 00:00:00Z (xsd:dateTime)
exact match	wds:Q60054745-C53DE0E9-E288-4D49-B631-5930E1821549
exact match	https://scigraph.springernature.com/pub.10.1007/s002130050952
author name string	wds:Q60054745-23D62CC4-8D83-49EA-8E25-9D7AB5FDA987 wds:Q60054745-DFBA05B2-0E43-4939-A82F-1DFDCFDEEA45
author name string	L H Tecott S P Vickers
rdfs:label	Reduced satiating effect of d -fenfluramine in serotonin 5-HT 2C receptor mutant mice (en) Reduced satiating effect of d -fenfluramine in serotonin 5-HT 2C receptor mutant mice (nl)
skos:prefLabel	Reduced satiating effect of d -fenfluramine in serotonin 5-HT 2C receptor mutant mice (en) Reduced satiating effect of d -fenfluramine in serotonin 5-HT 2C receptor mutant mice (nl)
name	Reduced satiating effect of d -fenfluramine in serotonin 5-HT 2C receptor mutant mice (en) Reduced satiating effect of d -fenfluramine in serotonin 5-HT 2C receptor mutant mice (nl)
author	wds:Q60054745-402FFF20-685D-46D7-85CD-055B1625B962 wds:Q60054745-6718731A-E547-470A-B62D-62589E90C8ED
author	Colin T Dourish Pete Clifton
title	wds:Q60054745-2B459EE0-7503-4763-ADBB-27BCFCBAF98D
title	Reduced satiating effect of d-fenfluramine in serotonin 5-HT(2C) receptor mutant mice (en)
page(s)	wds:Q60054745-CE8BDAE0-8A5E-4147-BD7D-8BD09CBE7381
page(s)	309-314
instance of	wds:Q60054745-980EE88E-146B-443A-B31A-A0202A3DBDCF
instance of	scholarly article
main subject	wds:Q60054745-e99c6568-e05a-4467-a0cc-9e1d5592570f
main subject	wd:Q167934
PubMed ID	wds:Q60054745-6F59577F-F308-4E1D-BBFB-E3644EB74300
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/10353435
PubMed ID	10353435
published in	wds:Q60054745-3CDF9CD4-0829-4450-8DE8-EBEE8EA375FB
published in	Psychopharmacology
issue	wds:Q60054745-A496EB01-6545-4D5E-8930-FC2AE0D6293C
volume	wds:Q60054745-F4561ED7-5D1F-4EDE-90E9-F4B6C27C0987
issue	3
volume	143
DOI	wds:Q60054745-5EC1A2CA-EB36-408B-A026-967018136575
DOI	http://dx.doi.org/10.1007/S002130050952
DOI	10.1007/S002130050952
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q60054745
is cites work of	Complex HTR2C linkage disequilibrium and promoter associations with body mass index and serum leptin. Dual dopamine/serotonin releasers as potential medications for stimulant and alcohol addictions Selective serotonin 5-HT(2C) receptor activation suppresses the reinforcing efficacy of cocaine and sucrose but differentially affects the incentive-salience value of cocaine- vs. sucrose-associated cues Leptin and post-prandial satiety: acute central leptin more potently reduces meal frequency than meal size in the rat. Characterization of the 5-HT2C receptor agonist lorcaserin on efficacy and safety measures in a rat model of diet-induced obesity Modification of human 5-HT(2C) receptor function by Cys23Ser, an abundant, naturally occurring amino-acid substitution. Serotonin releasing agents. Neurochemical, therapeutic and adverse effects Effects of fluoxetine and d-fenfluramine on cocaine-seeking behavior in rats Pharmacogenetics and the serotonin system: initial studies and future directions. Pharmacological targeting of the serotonergic system for the treatment of obesity Anorexia induced by activation of serotonin 5-HT4 receptors is mediated by increases in CART in the nucleus accumbens Serotonergic drugs : effects on appetite expression and use for the treatment of obesity Evidence that hypophagia induced by d-fenfluramine and d-norfenfluramine in the rat is mediated by 5-HT2C receptors Intermittent, chronic fenfluramine administration to rats repeatedly suppresses food intake despite substantial brain serotonin reductions Parabrachial infusion of D-fenfluramine reduces food intake. Blockade by the 5-HT(1B) antagonist SB-216641. 5-HT1B receptor knockout mice show a compensatory reduction in 5-HT2C receptor function. Oral administration of the 5-HT2Creceptor agonist, mCPP, reduces body weight gain in rats over 28 days as a result of maintained hypophagia. Attenuated response to stress and novelty and hypersensitivity to seizures in 5-HT4 receptor knock-out mice. Reduced hypophagic effects of d-fenfluramine and the 5-HT2C receptor agonist mCPP in 5-HT1B receptor knockout mice Fluvoxamine, a selective serotonin reuptake inhibitor, and 5-HT2C receptor inactivation induce appetite-suppressing effects in mice via 5-HT1B receptors H1-histamine receptor affinity predicts short-term weight gain for typical and atypical antipsychotic drugs. A serotonin-dependent mechanism explains the leptin regulation of bone mass, appetite, and energy expenditure Finding new tricks for old drugs: an efficient route for public-sector drug discovery Pharmacological characterisation of the agonist radioligand binding site of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors Animal models of obsessive-compulsive disorder: utility and limitations Animal models of obsessive-compulsive spectrum disorders Compulsive behavior in the 5-HT2C receptor knockout mouse A serotonin and melanocortin circuit mediates D-fenfluramine anorexia Serotonin 2C receptor activates a distinct population of arcuate pro-opiomelanocortin neurons via TRPC channels Modulation of 5-HT(2A) receptor-mediated head-twitch behaviour in the rat by 5-HT(2C) receptor agonists Serotonergic drugs and valvular heart disease Therapeutic and adverse actions of serotonin transporter substrates 5-HT2CRs expressed by pro-opiomelanocortin neurons regulate energy homeostasis Comparative effects of continuous infusion of mCPP, Ro 60-0175 and d-fenfluramine on food intake, water intake, body weight and locomotor activity in rats. Behavioral seizure correlates in animal models of epilepsy: a road map for assay selection, data interpretation, and the search for causal mechanisms Aripiprazole, a novel atypical antipsychotic drug with a unique and robust pharmacology. Meal patterns of free feeding rats treated with clozapine, olanzapine, or haloperidol Cellular and molecular alterations in mice with deficient and reduced serotonin transporters Medicinal strategies in the treatment of obesity Modulation of the central melanocortin system by leptin, insulin, and serotonin: co-ordinated actions in a dispersed neuronal network Central nervous control of energy and glucose balance: focus on the central melanocortin system Lorcaserin and pimavanserin: emerging selectivity of serotonin receptor subtype-targeted drugs Evidence that the anorexia induced by lipopolysaccharide is mediated by the 5-HT2C receptor Integrated Approaches for Genome-wide Interrogation of the Druggable Non-olfactory G Protein-coupled Receptor Superfamily Aripiprazole added to overweight and obese olanzapine-treated schizophrenia patients. Ziprasidone as an adjuvant for clozapine- or olanzapine-associated medical morbidity in chronic schizophrenia Dynamic 5-HT2C receptor editing in a mouse model of obesity Synergistic impairment of glucose homeostasis in ob/ob mice lacking functional serotonin 2C receptors Serotonin and the regulation of mammalian energy balance Lorcaserin: an investigational serotonin 2C agonist for weight loss Mice overexpressing the 5-hydroxytryptamine transporter show no alterations in feeding behaviour and increased non-feeding responses to fenfluramine. Investigating interactions between phentermine, dexfenfluramine, and 5-HT2C agonists, on food intake in the rat. Mouse models of serotonin receptor function: toward a genetic dissection of serotonin systems. Effect of (-)-trans-PAT, a novel 5-HT2C receptor agonist, on intake of palatable food in mice

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