About: Echinomycin: a bifunctional intercalating antibiotic

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scientific article published in Nature

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rdf:type	Item
description	artículu científicu (ast) wetenschappelijk artikel (nl) article publié dans la revue scientifique Nature (fr) scientific article published in Nature (en) Նեյչրում հրատարակված հոդված (hy) im Dezember 1974 veröffentlichter wissenschaftlicher Artikel (de) наукова стаття, опублікована в Nature в грудні 1974 (uk)
publication date	wds:Q59088008-AE64F438-B652-4B49-B331-347D63C40E0A
publication date	1974-12-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q59088008-2EB8C143-D079-48A8-9389-3696AB163D63
language of work or name	English
exact match	wds:Q59088008-5A1D9AF9-A2D2-4C3D-B569-EB2F578545B6
exact match	https://scigraph.springernature.com/pub.10.1038/252653a0
cites work	wds:Q59088008-0F62428F-2844-4C62-AA0D-4034CEE83F28 wds:Q59088008-15B1171E-A444-420B-ADD6-840D48CE90F7 wds:Q59088008-1BE3FA24-029D-4706-9978-060B7EF00A18 wds:Q59088008-1C1A7961-D73C-4111-B468-896CDBDDB78B wds:Q59088008-30BBB7A6-7219-4EAC-B787-F01787EB2B8E wds:Q59088008-3A1DA94A-B474-4D7B-A7C3-A6BBC77AB14D wds:Q59088008-3C46CE9C-86AA-4C70-BFFF-7C1481AE98A0 wds:Q59088008-3E3358AA-54E7-42E0-9A39-3F4FA71E7334 wds:Q59088008-44024162-35C4-4B3A-A9DC-7A3B98FC85E7 wds:Q59088008-4C5AD063-67E1-4B45-BB25-2FBCCE4F3855 wds:Q59088008-6741ACD4-AFBD-4471-BDA9-F28866E5B6E1 wds:Q59088008-9906FF88-5C09-40A7-8D7E-7DB2F8435C1A wds:Q59088008-9A428234-DA30-4FFB-83D3-C7D2AB9D47D2 wds:Q59088008-A90ED114-7023-4D79-A0D6-AE8169F01377 wds:Q59088008-AB3AD669-6E3C-47FB-B288-49BEC6B2F641 wds:Q59088008-BE42634A-264D-4B83-8F1F-C8CBAD4F76AE wds:Q59088008-C615248E-8461-40A1-B27D-79A5C820B547
cites work	The Nucleotide Sequence of the lac Operator Calculation of binding isotherms for heterogeneous polymers Sequence of a repressor-binding site in the DNA of bacteriophage lamda DNA of bacteriophage PM2: a closed circular double-stranded molecule ACTINOMYCIN BINDING TO DNA: MECHANISM AND SPECIFICITY Base Specificity in the Interaction of Polynucleotides with Antibiotic Drugs Drugs which affect the Structure and Function of DNA Studies on the binding of actinomycin D to DNA and DNA model polymers Studies of the binding of actinomycin and related compounds to DNA. Secondary structure of DNA depends on base composition Stereochemistry of actinomycin--DNA binding The interaction of closed circular DNA with intercalative dyes. I. The superhelix density of SV40 DNA in the presence and absence of dye. Effect of DNA length on the free energy of binding of an unwinding ligand to a supercoiled DNA Hydrodynamic shear breakage of DNA may produce single-chained terminals Stoffwechselprodukte von Actinomyceten. 15. Mitteilung. über die Konstitution von Echinomycin The structure of Triostin C DNA stiffening and elongation caused by the binding of ethidium bromide
author name string	wds:Q59088008-2101317D-B216-4A9C-A09C-4ACEE5FD2961 wds:Q59088008-55DB6B34-0578-44C0-AF56-CD9B41547B45
author name string	M J Waring L P Wakelin
rdfs:label	Echinomycin: a bifunctional intercalating antibiotic (en) Echinomycin: a bifunctional intercalating antibiotic (nl)
skos:prefLabel	Echinomycin: a bifunctional intercalating antibiotic (en) Echinomycin: a bifunctional intercalating antibiotic (nl)
name	Echinomycin: a bifunctional intercalating antibiotic (en) Echinomycin: a bifunctional intercalating antibiotic (nl)
title	wds:Q59088008-C5E07BE4-9004-4C57-873F-32BF5752FE99
title	Echinomycin: a bifunctional intercalating antibiotic (en)
page(s)	wds:Q59088008-A26D1E08-A0CD-42A4-906C-3BD81B43EEF6
page(s)	653-657
instance of	wds:Q59088008-3207573D-AF45-4A50-AEE4-AAA78963C398
instance of	scholarly article
PubMed ID	wds:Q59088008-91EFAB9F-4439-4672-8538-4A7FE64E4EA8
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/4437614
PubMed ID	4437614
published in	wds:Q59088008-C1EF6B05-7332-4F5D-AFD1-9B8457C0382C
published in	Nature
issue	wds:Q59088008-819D22CC-4041-442C-AB94-5CC4087C1050
volume	wds:Q59088008-42A2ED34-FBB9-4BCC-994E-BFD3F92F6E68
issue	5485
volume	252
DOI	wds:Q59088008-BD352413-792E-47A6-828A-6B22A504DEC5
DOI	http://dx.doi.org/10.1038/252653A0
DOI	10.1038/252653A0
Dimensions Publication ID	wds:Q59088008-D56A9CB2-9BF2-449C-98E9-6D2CA059C32D
Dimensions Publication ID	1002928675
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q59088008
is cites work of	Directed biosynthesis of novel derivatives of echinomycin by Streptomyces echinatus. I. Effect of exogenous analogues of quinoxaline-2-carboxylic acid on the fermentation. Echinomycin Binding Sites on DNA Explorations of catalytic domains in non-ribosomal peptide synthetase enzymology Antiamoebic properties of the actinomycete metabolites echinomycin A and tirandamycin A Echinomycin inhibits chromosomal DNA replication and embryonic development in vertebrates Peptides with anticancer use or potential. Proton NMR study of the [d(ACGTATACGT)]2-2echinomycin complex: conformational changes between echinomycin binding sites Localized chemical reactivity in DNA associated with the sequence-specific bisintercalation of echinomycin DNA structural variations produced by actinomycin and distamycin as revealed by DNAase I footprinting. Kakadumycins, novel antibiotics from Streptomyces sp NRRL 30566, an endophyte of Grevillea pteridifolia Bisintercalator natural products with potential therapeutic applications: isolation, structure determination, synthetic and biological studies. Antitumour drug-DNA interactions: NMR studies of echinomycin and chromomycin complexes Echinomycin-induced hypersensitivity to osmium tetroxide of DNA fragments incapable of forming Hoogsteen base pairs A one-pot catalyst-free synthesis of functionalized pyrrolo[1,2-a]quinoxaline derivatives from benzene-1,2-diamine, acetylenedicarboxylates and ethyl bromopyruvate The heptad repeat in the largest subunit of RNA polymerase II binds by intercalating into DNA Intercalative binding to DNA of antitumour drugs derived from 3-nitro-1,8-naphthalic acid Design of sequence-specific DNA binding molecules for DNA methyltransferase inhibition Probing ligand binding to duplex DNA using KMnO4 reactions and electrospray ionization tandem mass spectrometry DNA polyintercalating drugs: DNA binding of diacridine derivatives Identification of genotype-selective antitumor agents using synthetic lethal chemical screening in engineered human tumor cells Echinomycin and distamycin induce rotation of nucleosome core DNA.

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