About: Aberrant rearrangements contribute significantly to the allelic exclusion of immunoglobulin gene expression

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About: Aberrant rearrangements contribute significantly to the allelic exclusion of immunoglobulin gene expression Goto Sponge NotDistinct Permalink

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scientific article published in Nature

Attributes	Values
rdf:type	Item
description	artículu científicu (ast) wetenschappelijk artikel (nl) article publié dans la revue scientifique Nature (fr) scientific article published in Nature (en) im April 1981 veröffentlichter wissenschaftlicher Artikel (de) наукова стаття, опублікована в Nature у квітні 1981 (uk)
publication date	wds:Q59085816-C5612347-F7E6-49AD-A085-E3FD2A6A32FA
publication date	1981-04-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q59085816-7D2B5DD3-D590-4B69-A70A-8DF105D5F517
language of work or name	English
exact match	wds:Q59085816-C31D8AB3-9470-461D-97F7-54963E911A59
exact match	https://scigraph.springernature.com/pub.10.1038/290372a0
cites work	wds:Q59085816-057C3873-C81F-46B7-9877-BB3F5C10459E wds:Q59085816-05C2C63C-7082-4024-92D1-4BC7B0D471C3 wds:Q59085816-11E54B53-6899-4799-871D-C8540FE991C0 wds:Q59085816-29F1060F-ED8A-4EED-AC1D-A04C07C6FCCF wds:Q59085816-37ECDC6F-B402-40C9-A95A-F57406DC5B85 wds:Q59085816-3E75E938-C1D9-4659-A7A4-31B454A8F2A7 wds:Q59085816-40E86744-E917-4652-A1BA-A7940DE0FF04 wds:Q59085816-4AFD46C7-25A6-4022-AB3E-F79B815E25D2 wds:Q59085816-52C17439-72AB-48C4-8CF6-6648D1D11ED3 wds:Q59085816-541651FA-B23E-4E7D-9CAB-F43465B310E4 wds:Q59085816-569D968F-E5C6-4C6B-B255-AC1D2519A14B wds:Q59085816-5C6A5143-3A5B-41C9-84EB-64776F80A002 wds:Q59085816-729A4A6D-C09C-40AB-94B9-4FD78BA7955D wds:Q59085816-75F2EFD7-2349-47F4-9BDB-76D649B43CB4 wds:Q59085816-7C940011-767E-4D89-ACFB-DC73FA3522E7 wds:Q59085816-7DD11DEE-66A1-4B46-AA78-7F1DDB6E92F0 wds:Q59085816-82770A5C-777B-482B-AC53-B96415F143D7 wds:Q59085816-88541893-DD09-427B-A7A3-465D417BE1D9 wds:Q59085816-8CCF3CF2-2CAF-45F9-9336-778F2E8C0BE4 wds:Q59085816-923F270A-4C50-479A-A637-A69CC116E7A8 wds:Q59085816-9EB6758D-DC37-4124-B691-2AB1C48C02F7 wds:Q59085816-9ED6DFD7-F3AF-4B4D-85F9-68271FFEC8A6 wds:Q59085816-9EDA0CE6-BF49-4BB0-BA87-64D9FBC8E427 wds:Q59085816-AFCF2FF2-0358-4E7C-BE6B-68DB0E52A7F1 wds:Q59085816-CD354708-0602-415E-96E4-9FCAC2BCDF1F wds:Q59085816-DF2EC198-A3F4-47A6-8136-8A9F3F163F14 wds:Q59085816-ECDF68ED-DA1C-43A7-86CB-6B4F9978CB3A wds:Q59085816-F05D2E4D-B0CF-43E9-B436-FD4D4D8A4296
cites work	Sequences of five potential recombination sites encoded close to an immunoglobulin kappa constant region gene Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I Immunoglobulin gene rearrangement in immature B cells An immunoglobulin heavy chain variable region gene is generated from three segments of DNA: VH, D and JH. Identification of a third type of lambda light chain in mouse immunoglobulins DNA clones containing mouse immunoglobulin kappa chain genes isolated by in vitro packaging into phage lambda coats Sequences at the somatic recombination sites of immunoglobulin light-chain genes Variation in the crossover point of kappa immunoglobulin gene V-J recombination: evidence from a cryptic gene Functional and non-functional joining in immunoglobulin light chain genes of a mouse myeloma. Two types of somatic recombination are necessary for the generation of complete immunoglobulin heavy-chain genes. An immunoglobulin heavy-chain gene is formed by at least two recombinational events Detection of specific sequences among DNA fragments separated by gel electrophoresis 5' flanking region of immunoglobulin heavy chain constant region genes displays length heterogeneity in germlines of inbred mouse strains Cloning of immunoglobulin kappa light chain genes from mouse liver and myeloma MOPC 173 Transcription of mouse kappa chain genes: implications for allelic exclusion Mouse pre-B cells synthesize and secrete mu heavy chains but not light chains A mutant immunoglobulin light chain is formed by aberrant DNA- and RNA-splicing events. RNA splicing generates a variant light chain from an aberrantly rearranged kappa gene A complete immunoglobulin gene is created by somatic recombination Activity of multiple light chain genes in murine myeloma cells producing a single, functional light chain Rearrangement of immunoglobulin genes Organization and expression of immunoglobulin genes in fetal liver hybridomas Somatic rearrangements forming active immunoglobulin mu genes in B and T lymphoid cell lines. Cmu gene rearrangement of mouse immunoglobulin genes in normal B cells occurs on both the expressed and nonexpressed chromosomes Rearrangement of immunoglobulin heavy chain genes during B-lymphocyte development as revealed by studies of mouse plasmacytoma cells CH gene rearrangements in IgM-bearing B cells and in the normal splenic DNA component of hybridomas making different isotypes of antibody Selective suppression of the transcription of ribosomal genes in mouse-human hybrid cells V–J joining of immunoglobulin κ genes only occurs on one homologous chromosome
author name string	wds:Q59085816-6F7A99D1-8D22-4732-95CC-3B517DE89430 wds:Q59085816-8358A68C-7E22-4BE0-8080-CC0EFC57DD94 wds:Q59085816-A829C4D0-07C6-47A8-81B8-B8FE56BA2862 wds:Q59085816-F73A9727-5ED6-49FE-8BBF-3ED6C7F80DE0
author name string	K Karjalainen M Weigert R P Perry C Coleclough
rdfs:label	Aberrant rearrangements contribute significantly to the allelic exclusion of immunoglobulin gene expression (en) Aberrant rearrangements contribute significantly to the allelic exclusion of immunoglobulin gene expression (nl)
skos:prefLabel	Aberrant rearrangements contribute significantly to the allelic exclusion of immunoglobulin gene expression (en) Aberrant rearrangements contribute significantly to the allelic exclusion of immunoglobulin gene expression (nl)
name	Aberrant rearrangements contribute significantly to the allelic exclusion of immunoglobulin gene expression (en) Aberrant rearrangements contribute significantly to the allelic exclusion of immunoglobulin gene expression (nl)
title	wds:Q59085816-AC93FE2D-FF9F-41B9-BDAC-E5E91EB96974
title	Aberrant rearrangements contribute significantly to the allelic exclusion of immunoglobulin gene expression (en)
page(s)	wds:Q59085816-4AB50F37-4697-4EB5-BD0D-AAAAC6619423
page(s)	372-378
instance of	wds:Q59085816-E9C32AEC-8869-4DDF-8254-25675CCB2592
instance of	scholarly article
PubMed ID	wds:Q59085816-44EF392F-611F-4530-BFB8-A1995DE14380
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/6783959
PubMed ID	6783959
published in	wds:Q59085816-B3460DBA-B911-4E61-B6A0-A37AA7E76D21
published in	Nature
issue	wds:Q59085816-6D4CA59E-33BB-4742-99BD-F056CE9F71FC
volume	wds:Q59085816-25FF4977-1604-4588-87EE-7C6BC8F76996
issue	5805
volume	290
number of pages	wds:Q59085816-FA1BE0C6-246E-48C2-9F56-216A5936B84A
number of pages	7 (xsd:decimal)

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