About: Glycogen Synthase Kinase-3β Inhibition Attenuates Asthma in Mice

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scientific article published on 07 June 2007

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована у вересні 2007 (uk) article scientifique publié en 2007 (fr) im Juni 2007 veröffentlichter wissenschaftlicher Artikel (de) scientific article published on 07 June 2007 (en) artículu científicu espublizáu en xunu de 2007 (ast)
publication date	wds:Q58620305-9B886290-D501-419E-A0A7-7979AE7D796C
publication date	2007-06-07 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q58620305-FEB216B0-07F3-466C-965E-0A469BE9109A
language of work or name	English
cites work	wds:Q58620305-0F05F2DB-86D9-451F-923D-FE093C2DB92F wds:Q58620305-0F6BFAD4-DCAE-448C-B4FC-10984678EA7F wds:Q58620305-100809AA-65A9-4ABE-A907-B2EEFC1CC6C5 wds:Q58620305-11DED5CE-F3B6-4926-9C80-45E336EC7F57 wds:Q58620305-12A43742-BB69-4DF6-B9D1-4A21D418CDE9 wds:Q58620305-24C8061C-39BB-4CF9-9E29-C9E007EF4890 wds:Q58620305-3473AE74-3410-4934-9C83-7AC2875D5714 wds:Q58620305-3510C1F3-9D6B-43D5-92DC-9D76CF084507 wds:Q58620305-41F683D9-AE25-4218-8DE9-E48ADBD3AB3F wds:Q58620305-44BF4B10-EF6A-4EEB-999A-C68D849A9083 wds:Q58620305-4A0BCE40-B95B-4E69-9E7B-2E7EAC2DE119 wds:Q58620305-4C25760B-C74D-4217-843A-68E0E7C3E0B1 wds:Q58620305-53E393DE-7AA7-49AB-ACEF-930EDF11FAB1 wds:Q58620305-62DA6C8A-E419-4EC9-860F-4769FEBBBEBD wds:Q58620305-63C179B8-DA35-4151-ABEB-00C396583F3B wds:Q58620305-6789A467-2CA7-4046-862B-1A9E5A967692 wds:Q58620305-693A5300-03EF-4155-8994-300B40D8E266 wds:Q58620305-6B7259E7-5A72-4AF8-B725-8C93C982E8E0 wds:Q58620305-6BB8902F-C994-4490-8C01-4E07B77935B0 wds:Q58620305-6F12D7FB-EADB-49C8-87E5-4D17CA4F82ED wds:Q58620305-71078A56-C39A-43DC-B760-0C2C314BC713 wds:Q58620305-7348DBF3-F891-4FE0-9EF3-20EBC6271EED wds:Q58620305-7F7CE0C5-3A45-431F-981E-7BB27B40CF33 wds:Q58620305-8005FF8F-AC31-4209-BE62-CD105CCD4E6F wds:Q58620305-85CF06F7-60A9-460B-8BA6-CE7F2626BBA4 wds:Q58620305-8602D384-79E2-4A9D-806F-0AD8E420937C wds:Q58620305-959EFF04-D817-4547-BBF7-5BD099FE330A wds:Q58620305-9EB095E2-0D60-4868-AF91-9E5720B2014C wds:Q58620305-AC464CA9-7CC6-4E66-8AF3-9268D72C7B09 wds:Q58620305-AF43F561-B7F4-49BE-8DB5-AEF1CE5595A8 wds:Q58620305-B51B2B05-2D68-4807-BA28-A168B511FF84 wds:Q58620305-B755397A-967B-43B7-90BA-BB7A0E58CEF3 wds:Q58620305-C03DE6BA-655F-40AA-B520-7033AC53CF5C wds:Q58620305-CB15F266-7FEC-45F0-A977-264E491ED525 wds:Q58620305-CD521497-99FC-4888-998C-ABB5ACDCA558 wds:Q58620305-D14A6392-10B5-4151-B452-7EC9CB2CE62D wds:Q58620305-DB83DE45-225B-4B95-8C43-051730CE89EE wds:Q58620305-F1C78578-7592-4656-8B05-9B185E567D04 wds:Q58620305-F460AEFF-0231-4D71-9C13-941027A5D517 wds:Q58620305-F91987D2-EBBA-4926-8FD2-9F3B16575D56 wds:Q58620305-FB6F457C-0B87-467C-A9A2-C0137549165E
cites work	Tumor necrosis factor-alpha triggers mucus production in airway epithelium through an IkappaB kinase beta-dependent mechanism Pharmacological inhibitors of glycogen synthase kinase 3. To respond or not to respond: T cells in allergic asthma Expression of the Ym2 lectin-binding protein is dependent on interleukin (IL)-4 and IL-13 signal transduction: identification of a novel allergy-associated protein Reduction of experimental colitis in the rat by inhibitors of glycogen synthase kinase-3beta. GSK-3beta inhibitors attenuate the organ injury/dysfunction caused by endotoxemia in the rat. Asthma: mechanisms of disease persistence and progression Role of activator protein 1, nuclear factor-kappaB, and nuclear factor of activated T cells in IgE receptor-mediated cytokine expression in mature human mast cells. Acidic mammalian chitinase in asthmatic Th2 inflammation and IL-13 pathway activation Activation and localization of transcription factor, nuclear factor-kappaB, in asthma Persistent activation of nuclear factor-kappaB signaling pathway in severe uncontrolled asthma Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation NF-kappa B activation in airways modulates allergic inflammation but not hyperresponsiveness Nuclear factor-kappaB: its role in health and disease Toll-like receptor-mediated cytokine production is differentially regulated by glycogen synthase kinase 3. The effects of a monoclonal antibody directed against tumor necrosis factor-alpha in asthma. Structure of GSK3beta reveals a primed phosphorylation mechanism First non-ATP competitive glycogen synthase kinase 3 beta (GSK-3beta) inhibitors: thiadiazolidinones (TDZD) as potential drugs for the treatment of Alzheimer's disease Interleukin-13 in asthma pathogenesis. Mechanisms of eosinophil-associated inflammation Role of eosinophil chemotactic factor by T lymphocytes on airway hyperresponsiveness in a murine model of allergic asthma. The eosinophil Intrinsic defect in T cell production of interleukin (IL)-13 in the absence of both IL-5 and eotaxin precludes the development of eosinophilia and airways hyperreactivity in experimental asthma Allergen-induced peribronchial fibrosis and mucus production mediated by IkappaB kinase beta-dependent genes in airway epithelium Regulation of IL4 gene expression by T cells and therapeutic perspectives Repression of Inflammatory Gene Expression in Human Pulmonary Epithelial Cells by Small-Molecule I B Kinase Inhibitors Synthetic responses in airway smooth muscle Involvement of GSK-3beta in TWEAK-mediated NF-kappaB activation Genetic dissection of antigen receptor induced-NF-kappaB activation Inhibition of IKK down-regulates antigen + IgE-induced TNF production by mast cells: a role for the IKK-IkappaB-NF-kappaB pathway in IgE-dependent mast cell activation CD4(+) T cell-dependent airway mucus production occurs in response to IL-5 expression in lung. Chemokines: roles in leukocyte development, trafficking, and effector function Anti-inflammatory effects of mitogen-activated protein kinase kinase inhibitor U0126 in an asthma mouse model Interleukin (IL)-4-independent induction of immunoglobulin (Ig)E, and perturbation of T cell development in transgenic mice expressing IL-13. Leukotrienes mediate murine bronchopulmonary hyperreactivity, inflammation, and part of mucosal metaplasia and tissue injury induced by recombinant murine interleukin-13. Do inflammatory mediators influence the contribution of airway smooth muscle contraction to airway hyperresponsiveness in asthma? Selective blockade of NF-kappa B activity in airway immune cells inhibits the effector phase of experimental asthma. Ikappa-B kinase-2 inhibitor blocks inflammation in human airway smooth muscle and a rat model of asthma Increased lungkine and chitinase levels in allergic airway inflammation: a proteomics approach T-cell-receptor- and B-cell-receptor-mediated activation of NF-kappaB in lymphocytes ICAM-1 expression is highly NF-kappaB-dependent in A549 cells. No role for ERK and p38 MAPK.
author name string	wds:Q58620305-4DE7E373-7F59-4DFA-9B8F-FC7B128BE03A wds:Q58620305-709C6981-E798-4095-AB02-CCBD1D9A6300 wds:Q58620305-76BECA85-4137-46A6-91B6-F27FF8948982 wds:Q58620305-F7D87CFE-09A4-4571-B735-BFA398B3C2B7
author name string	W S Fred Wong Wupeng Liao Shuhui Lim

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