About: CD40 ligand mutations in X-linked immunodeficiency with hyper-IgM

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: CD40 ligand mutations in X-linked immunodeficiency with hyper-IgM Goto Sponge NotDistinct Permalink

An Entity of Type : wikibase:Item, within Data Space : wikidata.demo.openlinksw.com associated with source document(s)

scientific article published in Nature

Attributes	Values
rdf:type	Item
description	artículu científicu (ast) wetenschappelijk artikel (nl) article publié dans la revue scientifique Nature (fr) im Februar 1993 veröffentlichter wissenschaftlicher Artikel (de) scientific article published in Nature (en) наукова стаття, опублікована в Nature в лютому 1993 (uk)
publication date	wds:Q58478788-6A3B40D0-8E9D-423A-9BCF-0E69610ACF8F
publication date	1993-02-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q58478788-3CB50A67-6028-4C86-8FE5-4DBCECDD7A2E
language of work or name	English
exact match	wds:Q58478788-2E1F5F28-E1B7-4D59-9524-D08F23958C0D
exact match	https://scigraph.springernature.com/pub.10.1038/361541a0
cites work	wds:Q58478788-0E9ED2B2-055F-40DF-B387-F958E2BEA43B wds:Q58478788-242976DD-9EB1-4F5A-8BAA-0718A493C553 wds:Q58478788-3C114E72-E259-4C84-BCC5-7D99EFDD7488 wds:Q58478788-41ED363F-7FAD-4510-92F5-089B6D257323 wds:Q58478788-4960C1DE-61FB-41ED-BE56-F98AA68D1558 wds:Q58478788-53116295-4B02-47D8-B59D-7D078BABBDC7 wds:Q58478788-6D92AB3C-8701-42AD-89DC-194B142D86EF wds:Q58478788-8B25894A-A61C-4FFC-80D9-6FA02E447014 wds:Q58478788-8F760920-941C-43D8-9114-880F1A17B84B wds:Q58478788-96711F47-903B-43B7-A1AE-86EFFE12CA3A wds:Q58478788-9C7A7F8E-AAC8-4089-8449-AAAC101FE9BB wds:Q58478788-AD58490C-9919-4751-BAAC-28526C237CF2 wds:Q58478788-CC82548C-88E8-4D4B-8AAE-2447D0BABB00 wds:Q58478788-E30F241D-21E9-4EBD-AE7C-8CDE951D8A46 wds:Q58478788-F1FE353D-6217-49BE-83DF-9395863637CB wds:Q58478788-FA214363-FBE6-47A6-AA0A-F9695483E3F9 wds:Q58478788-FA7DD4FD-D3CD-4BD1-8D8A-4AAF782DF29B
cites work	Human CD40-ligand: molecular cloning, cellular distribution and regulation of expression by factors controlling IgE production A 39-kDa protein on activated helper T cells binds CD40 and transduces the signal for cognate activation of B cells Molecular and biological characterization of a murine ligand for CD40 Cloning of TRAP, a ligand for CD40 on human T cells Hyper immunoglobulin M immunodeficiency. (Dysgammaglobulinemia). Presence of immunoglobulin M-secreting plasmacytoid cells in peripheral blood and failure of immunoglobulin M-immunoglobulin G switch in B-cell differentiation An improved method for directly sequencing PCR amplified material using dimethyl sulphoxide CD40 and its ligand, an essential ligand-receptor pair for thymus-dependent B-cell activation Activated human T cells express a ligand for the human B cell-associated antigen CD40 which participates in T cell-dependent activation of B lymphocytes Cloning and expression of cDNA for human lymphotoxin, a lymphokine with tumour necrosis activity Evidence that in X-linked immunodeficiency with hyperimmunoglobulinemia M the intrinsic immunoglobulin heavy chain class switch mechanism is intact Evidence for a defect in "switch" T cells in patients with immunodeficiency and hyperimmunoglobulinemia M Molecular cloning of the complementary DNA for human tumor necrosis factor. A new superfamily of cell surface proteins related to the nerve growth factor receptor Mapping of the X-linked form of hyper-IgM syndrome (HIGM1) to Xq26 by close linkage to HPRT Regulation of IgE synthesis by cytokines Transcriptional diversity at the duplicated human CD8 beta loci. Hyper-IgM immunodeficiency syndrome: influence of lymphokines on in vitro maturation of peripheral B cells
author name string	wds:Q58478788-39A01718-E115-4295-AF20-FD182448C905 wds:Q58478788-687C9D11-1D9E-4926-B3E1-A1EEBBD8E617 wds:Q58478788-8ECFD461-DB52-421A-9972-A9C8780E72D4
author name string	Fischer A Bonnefoy JY Gauchat JF
rdfs:label	CD40 ligand mutations in X-linked immunodeficiency with hyper-IgM (en) CD40 ligand mutations in X-linked immunodeficiency with hyper-IgM (nl)
skos:prefLabel	CD40 ligand mutations in X-linked immunodeficiency with hyper-IgM (en) CD40 ligand mutations in X-linked immunodeficiency with hyper-IgM (nl)
name	CD40 ligand mutations in X-linked immunodeficiency with hyper-IgM (en) CD40 ligand mutations in X-linked immunodeficiency with hyper-IgM (nl)
author	wds:Q58478788-563E79C0-A4B6-48EA-B4A2-C692ED1D5BDF wds:Q58478788-B15611F8-F9EF-421A-9D12-56AF9FC65A1D
author	Geneviève de Saint Basile James P Di Santo
title	wds:Q58478788-92BAFC97-9A46-4935-A507-AD581B6E0245
title	CD40 ligand mutations in x-linked immunodeficiency with hyper-IgM (en)
page(s)	wds:Q58478788-3A5DA6CB-A34E-4E12-ADF9-F6E7EE9E58C8
page(s)	541-543
instance of	wds:Q58478788-49271E81-5A40-4C28-AD09-98C26635EDED
instance of	scholarly article
PubMed ID	wds:Q58478788-5722C78B-ECDE-4B2E-BAE8-D5D529649635
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/8094231
PubMed ID	8094231
published in	wds:Q58478788-EC6EFB02-341C-48D0-9047-0FF899F231C1
published in	Nature
issue	wds:Q58478788-CF3D42B8-8B67-49CF-898A-843517A697A0
volume	wds:Q58478788-88CACC60-E24C-4DB9-993A-21B6392DF75E
issue	6412
volume	361
DOI	wds:Q58478788-72D5CD57-B15E-46CD-980B-B42EA092E5A7
DOI	http://dx.doi.org/10.1038/361541A0
DOI	10.1038/361541A0
Dimensions Publication ID	wds:Q58478788-4CAD0DC2-7B21-447F-B967-74ABC662FF59
Dimensions Publication ID	1004806018
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q58478788
is cites work of	Cleavage of membrane-bound CD40 ligand is not required for inducing B cell proliferation and differentiation CD27 synergizes with CD40 to induce IgM, IgG, and IgA antibody responses of peripheral blood B cells in the presence of IL-2 and IL-10 Mutations of CD40 gene cause an autosomal recessive form of immunodeficiency with hyper IgM. The unique features of follicular T cell subsets Signals that influence T follicular helper cell differentiation and function. Targeting co-stimulatory pathways in gene therapy Therapeutic potential for blockade of the CD40 ligand, gp39. Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme Immunosuppressive strategies in transplantation Potential role of soluble CD40 in the humoral immune response impairment of uraemic patients Interleukin-10 induces immunoglobulin G isotype switch recombination in human CD40-activated naive B lymphocytes The biological outcome of CD40 signaling is dependent on the duration of CD40 ligand expression: reciprocal regulation by interleukin (IL)-4 and IL-12. Ligation of B7 with CD28/CTLA-4 on T cells results in CD40 ligand expression, interleukin-4 secretion and efficient help for antibody production by B cells CD40 and B cell antigen receptor dual triggering of resting B lymphocytes turns on a partial germinal center phenotype Partial immune reconstitution of X-linked hyper IgM syndrome with recombinant CD40 ligand Altered CD40 ligand induction in tolerant T lymphocytes

Faceted Search & Find service v1.16.117 as of May 05 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3239 as of May 5 2024, on Linux (x86_64-centos_6-linux-gnu), Single-Server Edition (378 GB total memory, 190 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software