About: Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease

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scholarly article by Patrizia Mecocci et al published November 1994 in Annals of Neurology

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в листопаді 1994 (uk) article scientifique publié en 1994 (fr) im November 1994 veröffentlichter wissenschaftlicher Artikel (de) scholarly article by Patrizia Mecocci et al published November 1994 in Annals of Neurology (en)
publication date	wds:Q58006825-C16C145F-6DA4-4C20-9FEF-096818CCCBBD
publication date	1994-11-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q58006825-7A9388E8-2303-4CE2-A00A-24531FD93652
language of work or name	English
author name string	wds:Q58006825-3974F73C-EAED-4703-B3AD-15935A103426
author name string	Usha MacGarvey
rdfs:label	Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease (en) Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease (nl)
skos:prefLabel	Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease (en) Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease (nl)
name	Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease (en) Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease (nl)
author	wds:Q58006825-503C49F5-93F1-4499-939F-8DF7948A848D wds:Q58006825-6AFB1D4F-BE61-4912-9604-356C4E31BECE
author	Patrizia Mecocci M. Flint Beal
title	wds:Q58006825-D95AEB3E-5AE1-404E-9E96-8C9E5178C02A
title	Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease (en)
page(s)	wds:Q58006825-129CD60B-20AE-49FC-9044-E73F28FD0CE7
page(s)	747-751
instance of	wds:Q58006825-2A95BCAA-5938-49D7-BF48-0B9AF4E0BF86
instance of	scholarly article
main subject	wds:Q58006825-A5B8F61B-4ACB-43BC-BD73-B9A14DE6AC3A wds:Q58006825-E745EDE7-4DE7-4FFA-BD9E-9578E7BFBE19 wds:Q58006825-F05314BC-6144-4C0D-BA3C-83C74ACADA74
main subject	mitochondrion Alzheimer's disease mitochondrial DNA
PubMed ID	wds:Q58006825-DEEBA3D7-CBCF-4552-93EA-B9B02957BB60
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/7979220
PubMed ID	7979220
published in	wds:Q58006825-4744E835-93D5-4EA2-98A8-53813F585C3D
published in	Annals of Neurology
issue	wds:Q58006825-9156CC07-BF07-4247-B27C-365F6F272B5B
volume	wds:Q58006825-A3791C52-867C-4403-897C-1CD38F2E09E8
issue	5
volume	36
DOI	wds:Q58006825-740364BC-0E4F-4F56-A408-12EEA9D4C72B
DOI	http://dx.doi.org/10.1002/ANA.410360510
DOI	10.1002/ANA.410360510
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q58006825
is cites work of	Apoptosis and increased generation of reactive oxygen species in Down's syndrome neurons in vitro. The modulation of metal bio-availability as a therapeutic strategy for the treatment of Alzheimer's disease Melatonin attenuates brain mitochondria DNA damage induced by potassium cyanide in vivo and in vitro Cellular and molecular mechanisms underlying perturbed energy metabolism and neuronal degeneration in Alzheimer's and Parkinson's diseases. Cognitive performance and biochemical markers in septum, hippocampus and striatum of rats after an i.c.v. injection of streptozotocin: a correlation analysis. Broad DNA repair responses in neural injury are associated with activation of the IL-6 pathway in cholesterol-fed rabbits. Protective effect of quercetin in primary neurons against Abeta(1-42): relevance to Alzheimer's disease Increased susceptibility of Alzheimer's disease temporal cortex to oxygen free radical-mediated processes. Oxidative-stress-dependent up-regulation of Bcl-2 expression in the central nervous system of aged Fisher-344 rats Stress, aging, and neurodegenerative disorders. Molecular mechanisms. Mass spectrometry and redox proteomics: applications in disease Current status of antioxidant therapy for Alzheimer's Disease. Roles of amyloid beta-peptide-associated oxidative stress and brain protein modifications in the pathogenesis of Alzheimer's disease and mild cognitive impairment Survival of hippocampal and cortical neurons in a mixture of MEM+ and B27-supplemented neurobasal medium The neuroprotective activities of melatonin against the Alzheimer beta-protein are not mediated by melatonin membrane receptors Quantitative cytochemistry of cytochrome oxidase and cellular morphometry of the human inferior colliculus in control and Alzheimer's patients. Common effects of lithium and valproate on mitochondrial functions: protection against methamphetamine-induced mitochondrial damage A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine An evaluation of the role of mitochondria in neurodegenerative diseases: mitochondrial mutations and oxidative pathology, protective nuclear responses, and cell death in neurodegeneration Phylogenetic analysis of the mitochondrial genome indicates significant differences between patients with Alzheimer disease and controls in a French-Canadian founder population Oxidative injury in diseases of the central nervous system: focus on Alzheimer's disease Splitting up the powerhouse: structural insights into the mechanism of mitochondrial fission Mutations in mitochondrial cytochrome c oxidase genes segregate with late-onset Alzheimer disease Plasma antioxidants are similarly depleted in mild cognitive impairment and in Alzheimer's disease. Vitamin E for Alzheimer's disease and mild cognitive impairment Activation of NF-kappaB protects hippocampal neurons against oxidative stress-induced apoptosis: evidence for induction of manganese superoxide dismutase and suppression of peroxynitrite production and protein tyrosine nitration. Somatic mitochondrial DNA mutations in cortex and substantia nigra in aging and Parkinson's disease Synergy between the C2 allele of transferrin and the C282Y allele of the haemochromatosis gene (HFE) as risk factors for developing Alzheimer's disease. Energy metabolism and oxidative stress: impact on the metabolic syndrome and the aging process Increased oxidative damage in nuclear and mitochondrial DNA in Alzheimer's disease. Oxidative damage to mitochondrial DNA and activity of mitochondrial enzymes in chronic active lesions of multiple sclerosis Evidence for parent of origin effect in late-onset Alzheimer disease Mitochondrial involvement in Alzheimer's disease Mechanisms of neuronal degeneration in Alzheimer's disease RNA in brain disease: no longer just "the messenger in the middle". Alzheimer's disease: the two-hit hypothesis RNA oxidation is a prominent feature of vulnerable neurons in Alzheimer's disease. Bioenergetic dysfunction and inflammation in Alzheimer's disease: a possible connection Blood markers of oxidative stress in Alzheimer's disease Plasma antioxidant status, immunoglobulin g oxidation and lipid peroxidation in demented patients: relevance to Alzheimer disease and vascular dementia Elevated levels of oxidative DNA damage in lymphocytes from patients with Alzheimer's disease Detection of oxidative DNA damage in lymphocytes of patients with Alzheimer's disease Cerebrospinal fluid levels of alpha-tocopherol (vitamin E) in Alzheimer's disease The Possible Role of Antioxidant Vitamin C in Alzheimer's Disease Treatment and Prevention Cognitive enhancement therapy for Alzheimer's disease. The way forward The relationship between oxidative/nitrative stress and pathological inclusions in Alzheimer's and Parkinson's diseases Biological markers for therapeutic trials in Alzheimer's disease. Proceedings of the biological markers working group; NIA initiative on neuroimaging in Alzheimer's disease Oxidative damage and cognitive dysfunction: antioxidant treatments to promote healthy brain aging Antioxidant therapies for Alzheimer's disease Antioxidants in central nervous system diseases: preclinical promise and translational challenges. Copper, iron and zinc in Alzheimer's disease senile plaques. Copper, iron, and zinc imbalances in severely degenerated brain regions in Alzheimer's disease: possible relation to oxidative stress. The contribution of mitochondria to common disorders

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