About: A Traceless Vascular-Targeting Antibody-Drug Conjugate for Cancer Therapy

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scholarly article by Gonçalo J. L. Bernardes et al published 15 December 2011 in Angewandte Chemie International Edition

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в грудні 2011 (uk) im Dezember 2011 veröffentlichter wissenschaftlicher Artikel (de) scholarly article by Gonçalo J. L. Bernardes et al published 15 December 2011 in Angewandte Chemie International Edition (en)
publication date	wds:Q57911965-7DB18798-171C-4F65-9F18-182FB88DDC82
publication date	2011-12-15 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q57911965-673B80D0-2849-42E2-B6C1-DD193D93A85F
language of work or name	English
cites work	wds:Q57911965-08D3F9AB-010E-437A-9108-AC069326494E wds:Q57911965-0957EEE6-3AC4-4C39-8077-E13F78316C3E wds:Q57911965-1DFDD529-35A2-47DB-B426-434D15CEE2DE wds:Q57911965-2C7396DD-78D7-434C-870D-8684F864F40D wds:Q57911965-3972375B-944C-449D-99F2-D9A4ED35A17C wds:Q57911965-3FFABC76-53BB-4320-87F7-4FC16FF526A4 wds:Q57911965-5D14855F-49B8-4814-A777-64B0386F7F21 wds:Q57911965-5F29D764-1A80-47B2-8072-EFFC35C25E68 wds:Q57911965-604B533F-CCCB-4304-9BFC-AF367BE51B5F wds:Q57911965-6713F314-5F1A-4084-998D-CEFA77E417AF wds:Q57911965-8E13FC32-F153-416E-8CC5-1621CA1C0284 wds:Q57911965-96EF392A-5E62-4CF9-B9E7-177DA3955948 wds:Q57911965-97AA500F-56B9-4C04-BBF9-04BF504B7EE4 wds:Q57911965-9D1B3FBC-BB44-493D-9C7A-4A3262672D75 wds:Q57911965-9ED46A55-A7DE-47A1-90FF-2D7282818FC6 wds:Q57911965-9F7A9097-5F46-40A3-9F7A-1574F0475FD9 wds:Q57911965-B0F438A2-43AD-459E-BBBA-9395FB933141 wds:Q57911965-B8EFBE96-06C9-420F-87C7-3497EBF9986D wds:Q57911965-BE99AC5C-C9A8-4045-B22F-5818E9CD06BD wds:Q57911965-CC11BA1B-AB40-47FD-8977-869393C5048B wds:Q57911965-CC49A1A2-99A6-4B5A-93A4-D018D164A1D9 wds:Q57911965-D4D89D83-8D00-407D-9279-5143BCC0D642 wds:Q57911965-D64359CB-A8E6-40C6-BFF9-7F9FD5EEEAED wds:Q57911965-FA67226C-9689-4FF4-A13F-6E1C0BFE5CF4 wds:Q57911965-FCDC8D43-2E3B-43C3-A3EB-C20094F0F0AA
cites work	Development trends for monoclonal antibody cancer therapeutics. Chemical modification of proteins at cysteine: opportunities in chemistry and biology. A chemically modified antibody mediates complete eradication of tumours by selective disruption of tumour blood vessels Antibody drug-conjugates targeting the tumor vasculature: Current and future developments Antibody-drug conjugates designed to eradicate tumors with homogeneous and heterogeneous expression of the target antigen Targeted cancer therapy: conferring specificity to cytotoxic drugs Potent antibody drug conjugates for cancer therapy Engineered antibody-drug conjugates with defined sites and stoichiometries of drug attachment. Tumour vascular targeting Imaging tumors with an albumin-binding Fab, a novel tumor-targeting agent. Site-specific conjugation of a cytotoxic drug to an antibody improves the therapeutic index. Targeting by affinity-matured recombinant antibody fragments of an angiogenesis associated fibronectin isoform Radioimmunotherapy of solid tumors by targeting extra domain B fibronectin: identification of the best-suited radioimmunoconjugate Selective targeting of tumoral vasculature: Comparison of different formats of an antibody (L19) to the ED-B domain of fibronectin Antibody targeted drugs as cancer therapeutics Potent antibody therapeutics by design Tumour parameters affected by combretastatin A-4 phosphate therapy in a human colorectal xenograft model in nude mice Brentuximab vedotin (SGN-35) for relapsed CD30-positive lymphomas Antibody-based targeting of the tumor vasculature A high-affinity human monoclonal antibody specific to the alternatively spliced EDA domain of fibronectin efficiently targets tumor neo-vasculature in vivo The Extra-domain A of Fibronectin Is a Vascular Marker of Solid Tumors and Metastases Expression of the oncofetal ED-B-containing fibronectin isoform in hematologic tumors enables ED-B-targeted 131I-L19SIP radioimmunotherapy in Hodgkin lymphoma patients Site-specific and stoichiometric conjugation of cationic porphyrins to antiangiogenic monoclonal antibodies Phase II study of the antibody drug conjugate trastuzumab-DM1 for the treatment of human epidermal growth factor receptor 2 (HER2)-positive breast cancer after prior HER2-directed therapy Antibody-based targeting of interferon-alpha to the tumor neovasculature: a critical evaluation
author name string	wds:Q57911965-4A3FC681-8843-46A8-9F06-DB25D792DE1D wds:Q57911965-52189C34-E249-4C8B-AD43-87BEAEA68E20
author name string	Isabelle Hartmann Kathrin Schwager
rdfs:label	A Traceless Vascular-Targeting Antibody-Drug Conjugate for Cancer Therapy (en) A Traceless Vascular-Targeting Antibody-Drug Conjugate for Cancer Therapy (nl)
skos:prefLabel	A Traceless Vascular-Targeting Antibody-Drug Conjugate for Cancer Therapy (en) A Traceless Vascular-Targeting Antibody-Drug Conjugate for Cancer Therapy (nl)
name	A Traceless Vascular-Targeting Antibody-Drug Conjugate for Cancer Therapy (en) A Traceless Vascular-Targeting Antibody-Drug Conjugate for Cancer Therapy (nl)
author	wds:Q57911965-113B75F5-C1B9-4A1E-A764-881373301D72 wds:Q57911965-932D82DD-991F-4580-BC73-43F81505A9AC wds:Q57911965-A73DDD84-3FA3-46E8-8C62-24AB3799158C wds:Q57911965-CC0B8E87-7CA9-4D2A-BF42-9FDE496798B4 wds:Q57911965-FE3E8CC1-3B9E-4DEE-9EFE-442DF78F9956
author	Dario Neri Jörg Scheuermann Gonçalo J. L. Bernardes Sabrina Trüssel Giulio Casi
title	wds:Q57911965-1A578546-6F97-4305-B54E-41A65B821FAC
title	A Traceless Vascular-Targeting Antibody-Drug Conjugate for Cancer Therapy (en)
page(s)	wds:Q57911965-CA9B4764-37E1-4E99-8C66-6E34645C8510
page(s)	941-944
instance of	wds:Q57911965-5EFF7FD4-9AD5-49E2-8945-FA82AE0D8DD4
instance of	scholarly article
main subject	wds:Q57911965-801F7ACC-099A-4193-9524-7A8569801AF4 wds:Q57911965-A10DC794-C700-464F-952F-D68764ED2030 wds:Q57911965-B129C04B-3869-40FF-93DB-EC1E6B438F22
main subject	general chemistry antibody catalysis
PubMed ID	wds:Q57911965-276E2813-1C79-4AE4-9D86-28B68AC8AE41
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/22173886
PubMed ID	22173886
published in	wds:Q57911965-58E2CD47-B6C6-4F5F-9701-B81C20925FD9
published in	Angewandte Chemie International Edition
issue	wds:Q57911965-5B8264D6-CA42-4B05-B45A-085B82C1D125
volume	wds:Q57911965-03BA9698-2B84-4FE6-A425-57D13AD30E3A
issue	4
volume	51

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