About: BCR–ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros

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scientific article published in Nature

Attributes	Values
rdf:type	Item
description	artículu científicu (ast) wetenschappelijk artikel (nl) article publié dans la revue scientifique Nature (fr) im April 2008 veröffentlichter wissenschaftlicher Artikel (de) নেচারে প্রকাশিত বৈজ্ঞানিক প্রবন্ধ (bn) scientific article published in Nature (en) наукова стаття, опублікована в Nature у квітні 2008 (uk)
publication date	wds:Q57734316-E6F04054-3DDD-49F1-A8ED-9A3F19C121A6
publication date	2008-04-13 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q57734316-4F3977D1-3293-4E4B-A0F5-E380A1BFDDC8
language of work or name	English
exact match	wds:Q57734316-65BA6C15-937F-4055-AA03-533E0B1C2FA6
exact match	https://scigraph.springernature.com/pub.10.1038/nature06866
cites work	wds:Q57734316-0B20C583-46AF-46B3-8444-0FBBC4642FCA wds:Q57734316-2FD55CD3-2609-4E53-85B8-5104A0AD15CD wds:Q57734316-3A9FF9BE-0245-4D6A-968D-31D1D30060B0 wds:Q57734316-44FFCCA6-07B1-4515-A1FF-DCF269A221F5 wds:Q57734316-4B27CE3A-2563-4BAD-B29B-599101536CE5 wds:Q57734316-531104FA-6EF4-4C10-A276-BC683E6A1938 wds:Q57734316-5569A94B-18B5-4558-8240-BD835A189BEA wds:Q57734316-59F71ADB-A05B-4E59-AD2C-08E35117A5E6 wds:Q57734316-63966DE6-E826-417A-BB38-6C603B51F3F8 wds:Q57734316-63FE450A-BF77-48F8-9FDE-71BBA0EF53FA wds:Q57734316-6FB29DAA-B898-4D7F-8234-6CFE9FD078E2 wds:Q57734316-706170C1-1318-4DCC-A58B-9D0835090827 wds:Q57734316-78A16071-D0EB-4DC5-BFDF-EE385A0413AE wds:Q57734316-7D770664-15D1-443B-B277-06BB40C65913 wds:Q57734316-7F667902-ED83-471D-A045-FBE7BC00053B wds:Q57734316-8303F5E5-F97B-4873-B4BF-94417358D6B8 wds:Q57734316-99CB85DD-9A89-4055-91D4-EED088255C9E wds:Q57734316-A632ACB8-12B5-4BB1-927F-A958C3B5B2F6 wds:Q57734316-A68F223E-B47C-44CD-B704-4E6CC620F454 wds:Q57734316-AE0619F1-23EF-4945-A0B7-E15FEBF75B11 wds:Q57734316-D7179C04-2A9A-4EEE-B268-EC86B51E22F2 wds:Q57734316-DBCC25EA-87B1-4695-8387-680E254B13EE wds:Q57734316-DCE68B1A-D90D-4DA3-B45C-95E053825066
cites work	Chronic Myeloid Leukemia — Advances in Biology and New Approaches to Treatment Selective defects in the development of the fetal and adult lymphoid system in mice with an Ikaros null mutation The lymphoid transcription factor LyF-1 is encoded by specific, alternatively spliced mRNAs derived from the Ikaros gene Quantitative high-throughput analysis of DNA methylation patterns by base-specific cleavage and mass spectrometry Arf gene loss enhances oncogenicity and limits imatinib response in mouse models of Bcr-Abl-induced acute lymphoblastic leukemia Expression of dominant-negative and mutant isoforms of the antileukemic transcription factor Ikaros in infant acute lymphoblastic leukemia The Ikaros gene encodes a family of functionally diverse zinc finger DNA-binding proteins The Ikaros gene is required for the development of all lymphoid lineages A dominant mutation in the Ikaros gene leads to rapid development of leukemia and lymphoma Characterizing the cancer genome in lung adenocarcinoma Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia Chronic myeloid leukaemia as a model of disease evolution in human cancer The RAG proteins and V(D)J recombination: complexes, ends, and transposition Hematopoietic stem cells and lymphoid progenitors express different Ikaros isoforms, and Ikaros is localized to heterochromatin in immature lymphocytes. Ikaros is critical for B cell differentiation and function. Expression of aberrantly spliced oncogenic ikaros isoforms in childhood acute lymphoblastic leukemia Expression of the Ikaros gene family in childhood acute lymphoblastic leukaemia Detection of different Ikaros isoforms in human leukaemias using real-time quantitative polymerase chain reaction Blast crisis in a murine model of chronic myelogenous leukemia Leading prognostic relevance of the BCR-ABL translocation in adult acute B-lineage lymphoblastic leukemia: a prospective study of the German Multicenter Trial Group and confirmed polymerase chain reaction analysis. BCR-ABL1 induces aberrant splicing of IKAROS and lineage infidelity in pre-B lymphoblastic leukemia cells Ikaros, Aiolos and Helios: transcription regulators and lymphoid malignancies Overexpression of dominant-negative Ikaros 6 protein is restricted to a subset of B common adult acute lymphoblastic leukemias that express high levels of the CD34 antigen
author name string	wds:Q57734316-0387C7F8-8AA9-4AAD-8F89-8927E85FC1BE wds:Q57734316-3B0825CB-45EF-450A-A9D6-D87AE2C91D33 wds:Q57734316-4CCBD081-3C22-4F58-9CDF-678A1A42CFD0 wds:Q57734316-9F419D06-A08E-4B9A-BBB9-5C83F8F98257 wds:Q57734316-AE79CFEF-40D8-42C2-9B4D-62C80B74ED6D wds:Q57734316-D51A655D-4AF2-4985-9805-6FE283A4270F wds:Q57734316-E20DD814-037F-4D2C-9531-3B9F5DF5176B wds:Q57734316-E691F09E-3A17-4067-AD58-29D21647EB1D wds:Q57734316-F32BD19E-46DC-4475-B47D-FF40B0C4BA6D
author name string	Jing Ma Mary V. Relling Charles G. Mullighan Ina Radtke James R. Downing Letha A. Phillips Timothy P. Hughes Sheila A. Shurtleff Christopher B. Miller
rdfs:label	BCR–ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros (en) BCR–ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros (nl)
skos:prefLabel	BCR–ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros (en) BCR–ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros (nl)
name	BCR–ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros (en) BCR–ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros (nl)
author	wds:Q57734316-32E2BA8A-1C96-4A31-B18E-3B7CC2F1669C wds:Q57734316-8FDE5AE1-B26A-4461-AAA2-00963574C5F5 wds:Q57734316-A0FCFB3B-434E-4EDB-86FF-B7273CAF7E30 wds:Q57734316-BBE98D66-567E-4CE6-8912-0D43BC004102
author	James T Dalton Ching-Hon Pui Michelle M Le Beau Deborah L. White
title	wds:Q57734316-759EEB68-5854-4CB7-952D-1DA7561AD2C2
title	BCR–ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros (en)
page(s)	wds:Q57734316-5A4808CD-79F9-4076-8DB1-D2CD6B50B9D5
page(s)	110-114
instance of	wds:Q57734316-02E23A17-D8CE-49D4-A6E5-48F117B5C54D
instance of	scholarly article
main subject	wds:Q57734316-6FA313D7-FCD8-4A8C-B9D8-C5A4663C6268
main subject	leukemia

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