About: Increased bone formation and osteosclerosis in mice overexpressing the transcription factor Fra-1

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article by Wolfram Jochum et al published September 2000 in Nature Medicine

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована у вересні 2000 (uk) im September 2000 veröffentlichter wissenschaftlicher Artikel (de) article by Wolfram Jochum et al published September 2000 in Nature Medicine (en)
publication date	wds:Q57675161-B70825EC-1DE9-4C48-9977-80FC36F94818
publication date	2000-09-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q57675161-6E20C78F-B9CA-4900-9077-301568FBE6FE
language of work or name	English
exact match	wds:Q57675161-6CD09771-606C-4F83-85C7-648433DE27BF
exact match	https://scigraph.springernature.com/pub.10.1038/79676
cites work	wds:Q57675161-0C8662D2-D836-40DC-B603-2F5F2E343634 wds:Q57675161-21983A61-87A3-4D18-B750-613CEAECF64D wds:Q57675161-2234446E-800B-42DF-8630-2C55352C469C wds:Q57675161-225993D4-83A0-4091-A68D-6578DB4DD64D wds:Q57675161-268D4765-0865-44E1-93C8-136E15F322E6 wds:Q57675161-2E59920A-08CF-41EA-8766-4CE1796C5A4E wds:Q57675161-30E4AA60-627A-4F62-8CCA-2A2484DE3778 wds:Q57675161-32289721-362D-40EF-8BE9-DF8588E328BE wds:Q57675161-6401A74C-13FF-4491-9660-18E1F4DB9ED0 wds:Q57675161-640610E9-9F75-4983-9193-6FCF88690F70 wds:Q57675161-653E9A6B-3104-4207-BF8C-066C87F2B6A5 wds:Q57675161-73D6B71B-CBA1-41C2-9E13-FFA54D235678 wds:Q57675161-75E1DBA0-E2B9-4CF0-A129-DA3BED17BD8B wds:Q57675161-7B93D1C5-7B74-48D8-84D3-E86B6C5453A9 wds:Q57675161-7C417314-96CC-4252-A493-81EE85DACA9B wds:Q57675161-84FAEEB9-305C-4CAA-BFA8-A107E504D0DC wds:Q57675161-86020CA7-C12C-4290-B243-583883AAB793 wds:Q57675161-9712EE36-E98D-4B17-8937-5A3691ACE933 wds:Q57675161-9756E91D-9C06-488D-BAFA-3B6F1640B90B wds:Q57675161-B284D0AD-2DD8-4C04-A9A9-19357BA3ED27 wds:Q57675161-CF6B6B43-4C9A-4F11-A6DD-FDA48578D789 wds:Q57675161-E33E8777-7C26-450A-918B-B4A4A701C6C1 wds:Q57675161-E92B764D-C7DB-4999-9130-9C68DDE65694 wds:Q57675161-EFFB755D-7EE0-4FAD-BBBA-32C025571C9E wds:Q57675161-F3925863-3BB0-4719-A341-D655F750C704 wds:Q57675161-F3956596-571A-4296-A1C6-00A39008147D
cites work	Leptin inhibits bone formation through a hypothalamic relay: a central control of bone mass c-Fos: a key regulator of osteoclast-macrophage lineage determination and bone remodeling Toward a molecular understanding of skeletal development Fos and bone cell development: lessons from a nuclear oncogene AP-1-like motif as a key to understanding the insulin-like growth factor I (IGF-I) gene regulation. The genetic transformation of bone biology Mice deficient in Abl are osteoporotic and have defects in osteoblast maturation Mutation of the mouse klotho gene leads to a syndrome resembling ageing Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells JNK2 is required for efficient T-cell activation and apoptosis but not for normal lymphocyte development. Autoinduction of transforming growth factor beta 1 is mediated by the AP-1 complex A Cbfa1-dependent genetic pathway controls bone formation beyond embryonic development Fosl1 is a transcriptional target of c-Fos during osteoclast differentiation Regulation of the differentiation and function of osteoclasts Increased bone formation in osteocalcin-deficient mice. fra-1: a serum-inducible, cellular immediate-early gene that encodes a fos-related antigen. Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee Retrovirus-induced insertional mutation in Mov13 mice affects collagen I expression in a tissue-specific manner Bone remodelling: a signalling system for osteoclast regulation Osteoblasts are target cells for transformation in c-fos transgenic mice Structure and chromosomal assignment of the mouse fra-1 gene, and its exclusion as a candidate gene for oc (osteosclerosis) Transformation by Fos proteins requires a C-terminal transactivation domain Fra-1 potentiates osteoclastic differentiation in osteoclast-macrophage precursor cell lines Bone and haematopoietic defects in mice lacking c-fos Pleiotropic effects of a null mutation in the c-fos proto-oncogene The product of a fos-related gene, fra-1, binds cooperatively to the AP-1 site with Jun: transcription factor AP-1 is comprised of multiple protein complexes.
author name string	wds:Q57675161-60E2E2F7-7A33-4BDB-9B95-F885006DD9CD wds:Q57675161-63594BBF-5C0E-439D-9702-4A188B82F258 wds:Q57675161-7C0E8205-4A8F-4372-8FDF-6C4B864F088F wds:Q57675161-AFC5E997-C023-4146-AB5B-17196CFC29C5
author name string	Wolfram Jochum Jean-Pierre David Hanns Plenk Candace Elliott
rdfs:label	Increased bone formation and osteosclerosis in mice overexpressing the transcription factor Fra-1 (en) Increased bone formation and osteosclerosis in mice overexpressing the transcription factor Fra-1 (nl)
skos:prefLabel	Increased bone formation and osteosclerosis in mice overexpressing the transcription factor Fra-1 (en) Increased bone formation and osteosclerosis in mice overexpressing the transcription factor Fra-1 (nl)
name	Increased bone formation and osteosclerosis in mice overexpressing the transcription factor Fra-1 (en) Increased bone formation and osteosclerosis in mice overexpressing the transcription factor Fra-1 (nl)
author	wds:Q57675161-25298B66-D49F-45F8-A5E0-69CE82B27E94 wds:Q57675161-40CDCA06-341E-4CF9-8EC8-13C98C07B68B wds:Q57675161-78B0490D-878D-44D2-9C7B-7001C615DDF2
author	Erwin F. Wagner Koichi Matsuo Anton Wutz
title	wds:Q57675161-88A88C3B-3849-4C14-B57F-18CDA63B1F8D
title	Increased bone formation and osteosclerosis in mice overexpressing the transcription factor Fra-1 (en)
page(s)	wds:Q57675161-CC114B8F-39FD-4694-8A28-44DA459E500E
page(s)	980-984
instance of	wds:Q57675161-AD3E8177-B12F-4890-AABC-47D5C7780B52
instance of	scholarly article
main subject	wds:Q57675161-FB4260D2-6536-48F6-A483-2117699BA243
main subject	overexpression
PubMed ID	wds:Q57675161-D5BC290A-C502-41FC-B716-C8028D142ECA
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/10973316
PubMed ID	10973316
published in	wds:Q57675161-A445BCD7-B4DD-4D49-B288-ACEB3AC5124B
published in	Nature Medicine
issue	wds:Q57675161-ED52BE96-AA0F-4831-9880-BBAA6894652E
volume	wds:Q57675161-CF2B8070-0523-40BA-A4E6-1E8CD0A25368
issue	9
volume	6

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