About: Role of NF-κB in p53-mediated programmed cell death

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scientific article published in Nature

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rdf:type	Item
description	artículu científicu (ast) wetenschappelijk artikel (nl) wüsseschaftlicher Artikel, wo im April 2000 veröffentlicht worden isch (gsw) im April 2000 veröffentlichter wissenschaftlicher Artikel (de) article publié dans la revue scientifique Nature (fr) নেচারে প্রকাশিত বৈজ্ঞানিক প্রবন্ধ (bn) scientific article published in Nature (en) наукова стаття, опублікована в Nature у квітні 2000 (uk)
publication date	wds:Q57248006-FF61C9CF-E411-4753-9977-FFC3D86E531D
publication date	2000-04-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q57248006-C4916A2E-82E7-4773-92E8-181FF1C8E0B4
language of work or name	English
exact match	wds:Q57248006-A2113A5C-82F5-4AF7-AA0D-9E1C847F8DA8
exact match	https://scigraph.springernature.com/pub.10.1038/35009130
cites work	wds:Q57248006-00AA9498-20F8-4778-B7B4-FFA838999B9C wds:Q57248006-092DE133-32B1-47AD-BD12-3A08F15F0AAA wds:Q57248006-376B0327-2E4B-4305-A196-EF1216FFD639 wds:Q57248006-431946CA-92C1-4F5A-9765-058DD32EFCCD wds:Q57248006-433CDED1-F08C-49EC-996A-555886871489 wds:Q57248006-4F531BBF-D98A-4C6C-BADC-61B6460A13F3 wds:Q57248006-520A06E9-0FCD-48BC-8FB8-E19A2571F2E6 wds:Q57248006-5E703043-7311-46B7-B4C0-82A8E44A8430 wds:Q57248006-5EC59A24-C5CF-446F-853E-82F2A51C7F08 wds:Q57248006-68E623C8-B662-489F-8BDD-9D33A2023937 wds:Q57248006-6A64D005-480A-43A1-B6DC-C9169045A1B9 wds:Q57248006-805C8F86-4038-4554-A62B-E6CA35759E5E wds:Q57248006-94665791-63A6-4502-B8A6-D1D4596174DB wds:Q57248006-95B3BCFB-3EA6-4AA9-AECE-5CF4BAA5235C wds:Q57248006-9C571419-2B0A-460D-B0C3-179D30087ECD wds:Q57248006-9FEEB294-3F9C-42DF-9B7E-8E929591C921 wds:Q57248006-A1D819BC-DB48-4997-8D19-4BC915464034 wds:Q57248006-A4C87956-F37A-4B2A-8AF5-B4101693F339 wds:Q57248006-A50E851E-82D2-48DC-8E94-39D25D2C2DD0 wds:Q57248006-A59E784D-6762-4503-81E7-54F9FB00600C wds:Q57248006-B0B53450-64A0-44CF-92BA-3D6DB9628132 wds:Q57248006-CE7A76D9-9DC7-4E65-BF49-380956A12EDB wds:Q57248006-D9261D5C-8CA7-4142-8544-EF12B9A605AF wds:Q57248006-E0AC1B2D-9E2D-4A0F-8304-5AEB986CE559 wds:Q57248006-E0FACBC7-381B-42AB-B522-24F8A897D68D wds:Q57248006-E41018ED-895D-455A-A0CA-F4DB3CCC3696 wds:Q57248006-ED2B1F08-F5B3-419A-A100-8E8527CCB99B wds:Q57248006-ED2FB1D4-AA8A-4844-BED1-693BD04E662C
cites work	Tumor necrosis factor (TNF)-mediated kinase cascades: bifurcation of nuclear factor-kappaB and c-jun N-terminal kinase (JNK/SAPK) pathways at TNF receptor-associated factor 2 The PEST-like sequence of I kappa B alpha is responsible for inhibition of DNA binding but not for cytoplasmic retention of c-Rel or RelA homodimers E2F-1 potentiates cell death by blocking antiapoptotic signaling pathways MAP3K-related kinase involved in NF-kappaB induction by TNF, CD95 and IL-1 A synthetic inhibitor of the mitogen-activated protein kinase cascade Death receptors: signaling and modulation Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kappa B The beginning of the end: IkappaB kinase (IKK) and NF-kappaB activation p53-dependent apoptosis modulates the cytotoxicity of anticancer agents The Bcl-2 protein family: arbiters of cell survival The cellular response to p53: the decision between life and death Transcriptional cross talk between NF-kappaB and p53. p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells Human papillomavirus 16 E6 expression disrupts the p53-mediated cellular response to DNA damage Characterization of structural p53 mutants which show selective defects in apoptosis but not cell cycle arrest IkappaB alpha is a target for the mitogen-activated 90 kDa ribosomal S6 kinase The 90-kDa ribosomal S6 kinase (pp90rsk) phosphorylates the N-terminal regulatory domain of IkappaBalpha and stimulates its degradation in vitro Expression of human p53 requires synergistic activation of transcription from the p53 promoter by AP-1, NF-kappaB and Myc/Max NF-kappaB to the rescue: RELs, apoptosis and cellular transformation Retinoids: present role and future potential Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation N- and C-terminal sequences control degradation of MAD3/I kappa B alpha in response to inducers of NF-kappa B activity Bcl-2 blocks p53-dependent apoptosis Innovative treatment programs against cancer: II. Nuclear factor-kappaB (NF-kappaB) as a molecular target Interaction of the baculovirus anti-apoptotic protein p35 with caspases. Specificity, kinetics, and characterization of the caspase/p35 complex. Induction of DNA synthesis and apoptosis are separable functions of E2F-1. Selective induction of p53 and chemosensitivity in RB-deficient cells by E1A mutants unable to bind the RB-related proteins E1A sensitizes cells to tumor necrosis factor-induced apoptosis through inhibition of IkappaB kinases and nuclear factor kappaB activities
author name string	wds:Q57248006-BBB59367-4D8F-43B3-B33C-9AA5B71ED655 wds:Q57248006-DA4DDC0E-BD02-42C7-AA04-B6D40316A5F6 wds:Q57248006-EEF71C3C-7875-4BB7-A99D-C4EEB6C96D0B
author name string	Vousden KH Rice NR Ernst MK
rdfs:label	Role of NF-κB in p53-mediated programmed cell death (en) Role of NF-κB in p53-mediated programmed cell death (nl)
skos:prefLabel	Role of NF-κB in p53-mediated programmed cell death (en) Role of NF-κB in p53-mediated programmed cell death (nl)
name	Role of NF-κB in p53-mediated programmed cell death (en) Role of NF-κB in p53-mediated programmed cell death (nl)
author	wds:Q57248006-ECF269E7-50F9-4AA0-B153-A06E4B1B786D
author	Kevin M Ryan
title	wds:Q57248006-607EFCFB-C975-47F0-9911-6011C1918C61
title	Role of NF-kappaB in p53-mediated programmed cell death (en)
page(s)	wds:Q57248006-72DCC37A-686F-48C4-AB45-6EC88B7E9ED1
page(s)	892-897
instance of	wds:Q57248006-2296161B-4B4B-4462-8FA2-23E5FE96DE44
instance of	scholarly article
main subject	wds:Q57248006-524D8514-2236-4C23-9FCB-657FFC0D8B24 wds:Q57248006-EB5CFB77-A8B0-4A3B-95C1-326FAB840EFC
main subject	cell death NF-κB
PubMed ID	wds:Q57248006-73D7C278-7DE1-41DC-BB9D-1271CADB05FD
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/10786798
PubMed ID	10786798
published in	wds:Q57248006-9CDED607-FD73-4D17-8320-A0F2E6A988C9
published in	Nature

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