About: Darell D. Bigner

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An Entity of Type : wikibase:Item, within Data Space : wikidata.demo.openlinksw.com associated with source document(s)

researcher

Attributes	Values
rdf:type	Item
field of work	wds:Q57195229-7E24E8D2-75E5-4490-B63E-E523B46310FE
field of work	oncology
description	forskare (sv) researcher (en) 연구원 (ko) 研究者 (ja) araştırmacı (tr) wetenschapper (nl) дослідник (uk) эрдэмтэн (mn) वैज्ञानिक (hi) изилдөөчү (ky) 研究者 (zh) հետազոտող (hy)
rdfs:label	Darell D Bigner (es) Darell D Bigner (nl) Darell D Bigner (ast) Darell D. Bigner (en) Darell D. Bigner (sq)
skos:prefLabel	Darell D Bigner (es) Darell D Bigner (nl) Darell D Bigner (ast) Darell D. Bigner (en) Darell D. Bigner (sq)
name	Darell D Bigner (es) Darell D Bigner (nl) Darell D Bigner (ast) Darell D. Bigner (en) Darell D. Bigner (sq)
instance of	wds:Q57195229-14D02D38-C007-4142-949C-60083F0A5540
instance of	Homo sapiens
skos:altLabel	Bigner (en) Bigner D. (en) Bigner D. D. (en) Bigner DD (en) D Bigner (en) D D Bigner (en) D. Bigner (en) D. D. Bigner (en) Darell Bigner (en) Darell D Bigner (en) Darell Doty Bigner (en)
occupation	wds:Q57195229-20A1B23A-4DC6-4615-B9F0-44053C94CE52 wds:Q57195229-3561B8D4-5887-4F96-966B-0630558B9400
employer	wds:Q57195229-FFFFFB74-4A85-4BB6-8C3B-152B79701DC3
NUKAT ID	wds:Q57195229-3974C7BC-D920-4B0D-8318-3B46E290912F
sex or gender	wds:Q57195229-0C090638-56D1-4FDC-A209-84CE5EA7BF36
ISNI	wds:Q57195229-68DC6CFF-3E5B-4583-A2DB-B6E2FBBA870F
VIAF ID	wds:Q57195229-717F9C9B-DEC1-4FD0-998E-87B4A3DA106C
IdRef ID	wds:Q57195229-980A585A-A8CB-4891-BD96-419370C8DE7E
official website	wds:Q57195229-42DFF2E8-AF50-4BC5-A299-1D652161F7BE
VIAF ID	http://viaf.org/viaf/10002383
IdRef ID	http://www.idref.fr/110807472/id
occupation	physician researcher
employer	Duke University
NUKAT ID	n2006146922
sex or gender	male
ISNI	0000000115934920
VIAF ID	10002383
IdRef ID	110807472
official website	https://scholars.duke.edu/person/bigne001
ORCID iD	wds:Q57195229-F3FDF65C-8E02-4987-BCEF-AE786DB47A02
ORCID iD	https://orcid.org/0000-0001-5548-4899
ORCID iD	0000-0001-5548-4899
is owl:sameAs of	Darell D. Bigner
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q57195229
is author of	IDH1 and IDH2 mutations in gliomas Mutations of the BRAF gene in human cancer The genetic landscape of the childhood cancer medulloblastoma Anaplastic human gliomas grown in athymic mice. Morphology and glial fibrillary acidic protein expression Treatment of human glioma and medulloblastoma tumor lines in athymic mice with diaziquone and diaziquone-based drug combinations. Therapeutic profile of the human glioma line D-54 MG in athymic mice. Treatment of five subcutaneous human glioma tumor lines in athymic mice with carmustine, procarbazine, and mithramycin Chromosomal composition of malignant human gliomas through serial subcutaneous transplantation in athymic mice. Growth and chemotherapeutic response in athymic mice of tumors arising from human glioma-derived cell lines. A novel low-molecular weight inhibitor of focal adhesion kinase, TAE226, inhibits glioma growth Effect of epidermal growth factor on glioma cell growth, migration, and invasion in vitro. EGFRvIII-specific chimeric antigen receptor T cells migrate to and kill tumor deposits infiltrating the brain parenchyma in an invasive xenograft model of glioblastoma Immunobiologic aspects of the brain and human gliomas. A review Immunobiology of human gliomas Immune responses of breast cancer patients to mutated epidermal growth factor receptor (EGF-RvIII, Delta EGF-R, and de2-7 EGF-R). Overall survival of newly diagnosed glioblastoma patients receiving carmustine wafers followed by radiation and concurrent temozolomide plus rotational multiagent chemotherapy L-amino acid oxidase (LOX) modulation of melphalan activity against intracranial glioma. Myeloablative temozolomide enhances CD8⁺ T-cell responses to vaccine and is required for efficacy against brain tumors in mice Medical diagnostic radiation exposures and risk of gliomas Mibefradil, a novel therapy for glioblastoma multiforme: cell cycle synchronization and interlaced therapy in a murine model. Evaluation of an internalizing monoclonal antibody labeled using N-succinimidyl 3-[131I]iodo-4-phosphonomethylbenzoate ([131I]SIPMB), a negatively charged substituent bearing acylation agent Radioiodination of internalizing monoclonal antibodies using N-succinimidyl 5-iodo-3-pyridinecarboxylate. Somatic mutations in the chromatin remodeling gene ARID1A occur in several tumor types Protein typing of circulating microvesicles allows real-time monitoring of glioblastoma therapy Chromosomal evolution in malignant human gliomas starts with specific and usually numerical deviations Tenascin-C, over expressed in lung cancer down regulates effector functions of tumor infiltrating lymphocytes Monoclonal antibodies for brain tumour treatment Enhancement of irinotecan (CPT-11) activity against central nervous system tumor xenografts by alkylating agents Phase I trial of O6-benzylguanine for patients undergoing surgery for malignant glioma. Characterization of the mechanisms of busulfan resistance in a human glioblastoma multiforme xenograft. Monitoring radiographic brain tumor progression Comparative genomic hybridization analysis of astrocytomas: prognostic and diagnostic implications

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