About: Delayed treatment of MS is associated with high CSF levels of IL-6 and IL-8 and worse future disease course

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About: Delayed treatment of MS is associated with high CSF levels of IL-6 and IL-8 and worse future disease course Goto Sponge NotDistinct Permalink

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scientific article published on 28 August 2018

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rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в серпні 2018 (uk) article scientifique publié en 2018 (fr) im August 2018 veröffentlichter wissenschaftlicher Artikel (de) artículu científicu espublizáu n'agostu de 2018 (ast) scientific article published on 28 August 2018 (en)
publication date	wds:Q57167230-385924F9-8BE9-456E-B9D4-DB944A1628B6
publication date	2018-08-28 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q57167230-4A5B758F-12D3-40F9-B338-F22AA328FB43
language of work or name	English
cites work	wds:Q57167230-04BA3C44-7CB2-4E4B-B8C3-801E91389C58 wds:Q57167230-0DF73AF9-80FD-4E93-886F-6CFBAF4DEFFE wds:Q57167230-12AEBE65-AD4D-433D-8F11-5E6F74872047 wds:Q57167230-1494B8DC-AE11-489B-B5D6-0871EC9583E0 wds:Q57167230-172E8ACD-D409-4BD7-ABFB-6C0D6DCCD772 wds:Q57167230-1E897C41-1C7C-410B-A372-1E86E823A5F2 wds:Q57167230-1EC9436F-0249-4CCE-BA0B-39FD1B37F4CD wds:Q57167230-21864457-7449-44B5-B91F-D768908F6625 wds:Q57167230-32AF79E5-41F2-4702-84D2-5D6FEA9B26A4 wds:Q57167230-35E4B79B-51E9-41A8-9CA0-9388EE242872 wds:Q57167230-3B43D65C-FDDE-4937-BF25-51E3C2F6C8C7 wds:Q57167230-4135C05A-D950-4205-95EC-BA4ABE355AD5 wds:Q57167230-4628769B-1EAC-4662-80C3-ECA6AEC20E09 wds:Q57167230-54467813-395E-403F-957A-F9BA1D0C2182 wds:Q57167230-5CC967A4-B830-4CAD-8D5C-CAF0A32370C3 wds:Q57167230-6A8671DC-708B-46B3-BD12-279324FBB5B4 wds:Q57167230-7E9FBA27-8E5F-4343-BA82-3C3D61D7FD00 wds:Q57167230-8017BA0E-62DF-4651-A114-0EFCAD99C4BF wds:Q57167230-807B39BE-C2F7-435D-B3A4-A4F76D2AACB2 wds:Q57167230-8DE265A2-6A84-4461-9F64-D91F37F68C81 wds:Q57167230-93E3AA05-1CEF-4D4D-9C43-073F61A08C98 wds:Q57167230-9E22FEA6-68BD-4A43-AF63-6704C33AAD30 wds:Q57167230-9ED30D19-11BC-43A4-A0B5-9DF893A1B3E6 wds:Q57167230-A3517AAC-D5A7-4DF7-810E-CB8CB4F14280 wds:Q57167230-B778131D-A71B-44D7-991E-12E0D7C266B4 wds:Q57167230-BA20AACE-148E-4444-94BB-51749E06142B wds:Q57167230-C3BEC91A-5D31-4049-AB94-D7FF15A1104B wds:Q57167230-C79175B5-2286-49C2-ADA2-B5C87CB4225F wds:Q57167230-CD6FE0F7-D94A-4B6D-AB12-BAB21B0AB708 wds:Q57167230-D0FDFF59-BB75-4508-9380-2B13A858F4CA wds:Q57167230-D7F857D4-9ABE-42EF-80C7-952A0339F717 wds:Q57167230-D819B975-9DDD-4351-BE84-F521B9F0D33A wds:Q57167230-DAC862D9-CAFB-45A6-8690-1C73E2E50716 wds:Q57167230-E5DA7452-C517-4584-B910-A118B5075463 wds:Q57167230-FD4B9D16-A612-4CEC-A11D-B95D7F7692B6 wds:Q57167230-FF4E8A86-27F5-406C-8FAB-471B7C000CA6
cites work	Diagnostic criteria for multiple sclerosis: 2010 revisions to the McDonald criteria Characteristic cerebrospinal fluid cytokine/chemokine profiles in neuromyelitis optica, relapsing remitting or primary progressive multiple sclerosis Inflammation triggers synaptic alteration and degeneration in experimental autoimmune encephalomyelitis Long-term effect of early treatment with interferon beta-1b after a first clinical event suggestive of multiple sclerosis: 5-year active treatment extension of the phase 3 BENEFIT trial Treatment with interferon beta-1b delays conversion to clinically definite and McDonald MS in patients with clinically isolated syndromes. Rating neurologic impairment in multiple sclerosis: An expanded disability status scale (EDSS) Intramuscular interferon beta-1a therapy initiated during a first demyelinating event in multiple sclerosis. CHAMPS Study Group Effect of early interferon treatment on conversion to definite multiple sclerosis: a randomised study Intrathecal activation of the IL-17/IL-8 axis in opticospinal multiple sclerosis Meningeal B-cell follicles in secondary progressive multiple sclerosis associate with early onset of disease and severe cortical pathology. Clinical relevance of brain volume measures in multiple sclerosis Normal-appearing white matter in multiple sclerosis is in a subtle balance between inflammation and neuroprotection A longitudinal study of brain atrophy in relapsing multiple sclerosis. The Multiple Sclerosis Collaborative Research Group (MSCRG). Mechanisms of axonal degeneration in EAE--lessons from CNTF and MHC I knockout mice Subclinical central inflammation is risk for RIS and CIS conversion to MS Cerebrospinal fluid IL-12p40, CXCL13 and IL-8 as a combinatorial biomarker of active intrathecal inflammation Tumor necrosis factor is elevated in progressive multiple sclerosis and causes excitotoxic neurodegeneration Interleukin-1β causes synaptic hyperexcitability in multiple sclerosis. Cerebrospinal fluid detection of interleukin-1β in phase of remission predicts disease progression in multiple sclerosis The measurement and clinical relevance of brain atrophy in multiple sclerosis Cytokine levels in the cerebrospinal fluid and serum of patients with multiple sclerosis IL-6 detection in multiple sclerosis brain. APC-derived cytokines and T cell polarization in autoimmune inflammation Interleukin-6 concentration in serum and cerebrospinal fluid in multiple sclerosis patients Progressive cerebral atrophy in MS: a serial study using registered, volumetric MRI Neurodegeneration and neuroprotection in multiple sclerosis and other neurodegenerative diseases. CSF cytokines/chemokines as biomarkers in neuroinflammatory CNS disorders: A systematic review Interleukin-1β alters glutamate transmission at purkinje cell synapses in a mouse model of multiple sclerosis. The 11-year long-term follow-up study from the randomized BENEFIT CIS trial Diagnosis of multiple sclerosis: 2017 revisions of the McDonald criteria. Laquinimod ameliorates excitotoxic damage by regulating glutamate re-uptake. Siponimod (BAF312) prevents synaptic neurodegeneration in experimental multiple sclerosis Differential effects of interferon-ß1b on cytokine patterns of CD4+ and CD8+ T cells derived from RRMS and PPMS patients Neurophysiology of synaptic functioning in multiple sclerosis. Cerebrospinal fluid and serum levels of interleukin-8 in patients with multiple sclerosis and its correlation with Q-albumin. Increased cerebrospinal fluid progranulin correlates with interleukin-6 in the acute phase of neuromyelitis optica spectrum disorder.
author name string	wds:Q57167230-1F864323-0427-4BFD-991E-013295AA6F15 wds:Q57167230-43F29136-3530-42F0-883D-6A31B185B6BF wds:Q57167230-452DA8FB-0FF0-47C6-AA84-30308DC5AF71 wds:Q57167230-4A408AE2-6649-418A-95EF-AE3FAB2C57A1 wds:Q57167230-613B9B30-223D-4D2B-B60A-BEF7721E8AED wds:Q57167230-B6AAA8F1-E0DA-4135-9012-2C1067D0872A wds:Q57167230-C9D699EC-C7C2-4EC4-B40C-34A0E1B7CD76 wds:Q57167230-FFB58D82-326E-40C6-8A0F-5A122178DCD4
author name string	Alessandra Musella Georgia Mandolesi Roberto Furlan Fabio Buttari Annamaria Finardi Doriana Landi Girolama A Marfia Fabrizia Monteleone
rdfs:label	Delayed treatment of MS is associated with high CSF levels of IL-6 and IL-8 and worse future disease course (en)

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