About: Carlos M Farinha

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An Entity of Type : wikibase:Item, within Data Space : wikidata.demo.openlinksw.com associated with source document(s)

researcher

Attributes	Values
rdf:type	Item
description	researcher (en) 연구원 (ko) 研究者 (ja) дослідник (uk) эрдэмтэн (mn) изилдөөчү (ky) 研究者 (zh) հետազոտող (hy) onderzoeker (nl)
rdfs:label	Carlos M Farinha (en) Carlos M Farinha (es) Carlos M Farinha (nl) Carlos M Farinha (ast)
skos:prefLabel	Carlos M Farinha (en) Carlos M Farinha (es) Carlos M Farinha (nl) Carlos M Farinha (ast)
name	Carlos M Farinha (en) Carlos M Farinha (es) Carlos M Farinha (nl) Carlos M Farinha (ast)
Scopus author ID	wds:Q57052067-96A81F8B-23B5-41AB-9758-995EE8696C1F
Scopus author ID	6603173042
given name	wds:Q57052067-1A1CAF05-9BB5-43D2-86B8-2AE1E1C1C9B4
given name	Carlos
instance of	wds:Q57052067-F56B6DFA-AA7A-47B7-B6EE-DEC27C129E2B
instance of	Homo sapiens
skos:altLabel	Carlos Farinha (en)
occupation	wds:Q57052067-153E0B4C-5532-4D88-A11F-7DE59998C911
employer	wds:Q57052067-3F26DF66-757C-46E0-A382-1502BDD9889C wds:Q57052067-74604FDA-F153-4521-8158-CA5BF9C161C6 wds:Q57052067-79D06B3C-976D-42DC-AE49-0AAA62088E6D
sex or gender	wds:Q57052067-A32933C6-06A4-43EA-BBDB-44AAD515C179
VIAF ID	wds:Q57052067-d8f3ee8a-30a2-4fca-897e-e8c4a90da8e0
GND ID	wds:Q57052067-30c6cc9e-1ef6-411f-b769-8829eedc66e2
educated at	wds:Q57052067-75C6D3C0-9462-43EA-AACA-04F14DCE40BD wds:Q57052067-76976E7E-86FF-4DC9-AB1B-A6A979F8698A
family name	wds:Q57052067-851D701B-0636-4964-84FA-630EA9ADA184
National Library of Israel J9U ID	wds:Q57052067-671747D5-E2D6-45A1-BEF4-5713D4A0F86C
official website	wds:Q57052067-08577B39-ACBF-4BE6-BFEC-597F19069C88
VIAF ID	http://viaf.org/viaf/578165930956368530007
GND ID	https://d-nb.info/gnd/1263579973
occupation	researcher
employer	University of Lisbon
sex or gender	male
VIAF ID	578165930956368530007
GND ID	1263579973
educated at	University of Lisbon
family name	Farinha
National Library of Israel J9U ID	987007407227605171
official website	http://webpages.fc.ul.pt/~cmfarinha/index.htm
ORCID iD	wds:Q57052067-741A2550-079D-47A7-8FA9-CC61A36ACE02
ORCID iD	https://orcid.org/0000-0002-5467-1710
ORCID iD	0000-0002-5467-1710
ResearcherID	wds:Q57052067-F99E5906-23ED-4E6C-A322-95F118E9F214
ResearcherID	A-7110-2010
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q57052067
is author of	Antibodies for CFTR studies. The human DnaJ homologue (Hdj)-1/heat-shock protein (Hsp) 40 co-chaperone is required for the in vivo stabilization of the cystic fibrosis transmembrane conductance regulator by Hsp70 Most F508del-CFTR is targeted to degradation at an early folding checkpoint and independently of calnexin A comparison of 14 antibodies for the biochemical detection of the cystic fibrosis transmembrane conductance regulator protein. Solubilizing Mutations Used to Crystallize One CFTR Domain Attenuate the Trafficking and Channel Defects Caused by the Major Cystic Fibrosis Mutation Biochemical methods to assess CFTR expression and membrane localization Revertants, low temperature, and correctors reveal the mechanism of F508del-CFTR rescue by VX-809 and suggest multiple agents for full correction. Unusually common cystic fibrosis mutation in Portugal encodes a misprocessed protein. Characterization of novel airway submucosal gland cell models for cystic fibrosis studies Methods for RNA extraction, cDNA preparation and analysis of CFTR transcripts. Measurements of Functional Responses in Human Primary Lung Cells as a Basis for Personalized Therapy for Cystic Fibrosis. Contribution of casein kinase 2 and spleen tyrosine kinase to CFTR trafficking and protein kinase A-induced activity. Control of cystic fibrosis transmembrane conductance regulator membrane trafficking: not just from the endoplasmic reticulum to the Golgi EPAC1 activation by cAMP stabilizes CFTR at the membrane by promoting its interaction with NHERF1. Analysis of genomic CFTR DNA. CFTR mutations altering CFTR fragmentation From the endoplasmic reticulum to the plasma membrane: mechanisms of CFTR folding and trafficking Increased efficacy of VX-809 in different cellular systems results from an early stabilization effect of F508del-CFTR. LMTK2-mediated phosphorylation regulates CFTR endocytosis in human airway epithelial cells Post-translational modifications of CFTR: insight into protein trafficking and cystic fibrosis disease. BAG-1 stabilizes mutant F508del-CFTR in a ubiquitin-like-domain-dependent manner Investigating Alternative Transport of Integral Plasma Membrane Proteins from the ER to the Golgi: Lessons from the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR). Proteomic interaction profiling reveals KIFC1 as a factor involved in early targeting of F508del-CFTR to degradation Regulation of ENaC biogenesis by the stress response protein SERP1. Rab GTPases regulate the trafficking of channels and transporters - a focus on cystic fibrosis. Partial rescue of F508del-CFTR channel gating with modest improvement of protein processing, but not stability by a dual-acting small molecule. Protein and lipid interactions - Modulating CFTR trafficking and rescue. Teaching biochemistry at Lisbon University-Facing the challenge of the Bologna Declaration in the 25th anniversary of the biochemistry course Folding Status Is Determinant over Traffic-Competence in Defining CFTR Interactors in the Endoplasmic Reticulum. Targeting of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Protein with a Technetium-99m Imaging Probe Mechanical Properties of Human Bronchial Epithelial Cells Expressing Wt- and Mutant CFTR Full Rescue of F508del-CFTR Processing and Function by CFTR Modulators Can Be Achieved by Removal of Two Regulatory Regions Improved Fmoc-solid-phase peptide synthesis of an extracellular loop of CFTR for antibody selection by the phage display technology
is author of	wds:Q40394646-EFE79980-A0DF-4DE2-927C-2FEE73DD4263 wds:Q57762321-FAA1AA58-548C-40A9-9E7B-305289BE8F17 wds:Q26824750-08A91533-0E76-463B-AF76-49489373B114 wds:Q38971505-5A479503-9693-4AC1-9F26-A4CF1C07FD6E wds:Q48227818-2CC8A3AC-8528-4C1E-AC08-0FC4EB06F44A wds:Q90678173-B1276AD5-4690-49EC-AC8F-CE2F40BB5B13 wds:Q42677991-E0B1168C-9845-4009-B0F9-405F7D65F40A wds:Q47214928-07F41F0E-8299-40BB-9AC8-121FBF1196F1 wds:Q30342357-5474438E-550A-489C-8E7A-F6163B1EB844

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