About: Extensive SAR and computational studies of 3-{4-[(benzylmethylamino)methyl]phenyl}-6,7-dimethoxy-2H-2-chromenone (AP2238) derivatives

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About: Extensive SAR and computational studies of 3-{4-[(benzylmethylamino)methyl]phenyl}-6,7-dimethoxy-2H-2-chromenone (AP2238) derivatives Goto Sponge NotDistinct Permalink

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description	wetenschappelijk artikel (nl) наукова стаття, опублікована в серпні 2007 (uk) im August 2007 veröffentlichter wissenschaftlicher Artikel (de)
publication date	wds:Q56994703-63A61F85-A301-4676-8F59-8EF93DA89BD1
publication date	2007-08-23 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q56994703-A6C93AAB-B6F3-4B6D-BF96-7E87C2D65C14
language of work or name	English
author name string	wds:Q56994703-049531A1-2C7A-41F1-9550-6BA5A92D554A wds:Q56994703-0A899E89-147B-47DE-AF55-5237B9942561 wds:Q56994703-4B56609A-EEBF-42C3-B5C6-8AEE480F350D wds:Q56994703-862E8089-E224-460C-AC8C-A17CB9380B9D wds:Q56994703-9573E4D7-A19B-4F22-9D6B-1C4A88B964FB wds:Q56994703-CAC28135-1ADD-4C99-A756-59B18982296C wds:Q56994703-D09187B4-12F4-4C7C-9952-2E4E667136AA wds:Q56994703-D576C702-A9F5-4226-BDB4-75A10A08FCB5
author name string	Andrea Cavalli Federica Belluti Maurizio Recanatini Alessandra Bisi Angela Rampa Silvia Gobbi Lorna Piazzi Stefano Rizzo
rdfs:label	Extensive SAR and computational studies of 3-{4-[(benzylmethylamino)methyl]phenyl}-6,7-dimethoxy-2H-2-chromenone (AP2238) derivatives (en) Extensive SAR and computational studies of 3-{4-[(benzylmethylamino)methyl]phenyl}-6,7-dimethoxy-2H-2-chromenone (AP2238) derivatives (nl)
skos:prefLabel	Extensive SAR and computational studies of 3-{4-[(benzylmethylamino)methyl]phenyl}-6,7-dimethoxy-2H-2-chromenone (AP2238) derivatives (en) Extensive SAR and computational studies of 3-{4-[(benzylmethylamino)methyl]phenyl}-6,7-dimethoxy-2H-2-chromenone (AP2238) derivatives (nl)
name	Extensive SAR and computational studies of 3-{4-[(benzylmethylamino)methyl]phenyl}-6,7-dimethoxy-2H-2-chromenone (AP2238) derivatives (en) Extensive SAR and computational studies of 3-{4-[(benzylmethylamino)methyl]phenyl}-6,7-dimethoxy-2H-2-chromenone (AP2238) derivatives (nl)
author	wds:Q56994703-7DBA54C7-D21E-4869-988A-622B221E4655 wds:Q56994703-E7058F34-6DDE-4CEF-B9CC-5980D4E99D82
author	Manuela Bartolini Vincenza Andrisano
title	wds:Q56994703-C26857AB-8B65-4F69-9F61-0EE88997F5B3
title	Extensive SAR and computational studies of 3-{4-[(benzylmethylamino)methyl]phenyl}-6,7-dimethoxy-2H-2-chromenone (AP2238) derivatives (en)
page(s)	wds:Q56994703-DBBD0AEE-3C23-4095-B6F9-314296C611BF
page(s)	4250-4
instance of	wds:Q56994703-461C8997-F7A9-4229-907F-79CCD8DF943D
instance of	scholarly article
PubMed ID	wds:Q56994703-27976FCF-0FED-4430-B1F2-95A6E4776B27
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/17655212
PubMed ID	17655212
published in	wds:Q56994703-C45EF8C7-8DF7-4948-8566-851CC4F35250
published in	Journal of Medicinal Chemistry
issue	wds:Q56994703-51013C3D-A087-4F65-B836-CC58B5469294
volume	wds:Q56994703-C1D131A9-F2FD-4004-ADBC-A33D5050E816
issue	17
volume	50
DOI	wds:Q56994703-E2CA3073-BE85-446C-B90D-AF3E82D8DB8A
DOI	http://dx.doi.org/10.1021/JM070100G
DOI	10.1021/JM070100G
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q56994703
is cites work of	A review on cholinesterase inhibitors for Alzheimer's disease The discovery of potential acetylcholinesterase inhibitors: a combination of pharmacophore modeling, virtual screening, and molecular docking studies. Molecular Docking Guided Comparative GFA, G/PLS, SVM and ANN Models of Structurally Diverse Dual Binding Site Acetylcholinesterase Inhibitors. New neurogenic lipoic-based hybrids as innovative Alzheimer's drugs with σ-1 agonism and β-secretase inhibition. Melatonin as a versatile molecule to design novel multitarget hybrids against neurodegeneration From the dual function lead AP2238 to AP2469, a multi-target-directed ligand for the treatment of Alzheimer's disease Synthesis and structure-activity relationships of novel amino/nitro substituted 3-arylcoumarins as antibacterial agents Synthesis and biological evaluation of 1, 3-dihydroxyxanthone mannich base derivatives as anticholinesterase agents Structure-activity relationships and binding mode in the human acetylcholinesterase active site of pseudo-irreversible inhibitors related to xanthostigmine Alzheimer's disease: identification and development of β-secretase (BACE-1) binding fragments and inhibitors by dynamic ligation screening (DLS). Huprines for Alzheimer's disease drug development Synthesis and adenosine receptors binding affinities of a series of 3-arylcoumarins. Multitarget Strategy to Address Alzheimer's Disease: Design, Synthesis, Biological Evaluation, and Computational Studies of Coumarin-Based Derivatives Kinetic and structural studies on the interactions of Torpedo californica acetylcholinesterase with two donepezil-like rigid analogues. Design and Synthesis of Novel Heterocyclic-Based 4-benzo[]chromene Moieties: Targeting Antitumor Caspase 3/7 Activities and Cell Cycle Analysis FeCl3-catalyzed dimerization/elimination of 1,1-diarylalkenes: efficient synthesis of functionalized 4H-chromenes.
is cites work of	wds:Q38684594-9BC8784B-CAF1-400A-B74E-2A6F1D631CEB wds:Q42928266-E26169EE-CA50-46AD-A475-D81724F31585 wds:Q51751563-33EAA6C3-A5DA-4AFB-9F4D-532923081143 wds:Q43958961-5B0B0B37-D9F2-4E24-838A-8802E0FE0EDF wds:Q34767547-7EF63CC2-8766-4DF3-B886-32ECF3146D8A wds:Q35823536-8EFE1113-2136-4AE0-9FC7-D806B30DE363 wds:Q36905746-CC385396-6110-42BC-9351-2343C45703BF wds:Q38084168-6A3AE29A-DD74-4954-AA9F-65245754C919 wds:Q52322708-78C24DBD-4456-4162-95B4-CA02C6583B7B wds:Q34564278-91284DD8-CAD2-41BC-922E-1E3D33D2A7E5 wds:Q64081526-371C6CEA-0CE6-4BA7-916D-58498A566356 wds:Q38088283-80C76319-FCC0-4033-9A99-8CCF023890B7 wds:Q39550895-5272D8C7-399A-405A-BAAE-A23207B297D0 wds:Q46119907-B950E452-168F-479F-8073-C5B7B766ABDF wds:Q38842928-7A1739CD-5077-42A4-B7A6-A9E6DDDB6276 wds:Q50074280-22A3B29E-A1B9-405A-B0FB-0E1A80650A18

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