About: Protection of Rpe65-deficient mice identifies rhodopsin as a mediator of light-induced retinal degeneration

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article by Christian Grimm et al published May 2000 in Nature Genetics

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в травні 2000 (uk) article scientifique publié en 2000 (fr) im Mai 2000 veröffentlichter wissenschaftlicher Artikel (de) article by Christian Grimm et al published May 2000 in Nature Genetics (en)
publication date	wds:Q56873521-929EC5CA-53FF-412A-9EA0-596B23796FC5
publication date	2000-05-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q56873521-7D6C93A4-3259-40B1-86F8-50E5105C5C02
language of work or name	English
exact match	wds:Q56873521-B56B64B5-87E8-45B1-9725-065F554239A0
exact match	https://scigraph.springernature.com/pub.10.1038/75614
cites work	wds:Q56873521-00CC182A-46C2-435B-A9D8-6C6CA34307BD wds:Q56873521-05E1AD61-D01A-469A-A0DE-869462CDC4F2 wds:Q56873521-0997258B-225A-4190-A411-5C9CD516D2BA wds:Q56873521-0B817C16-74F5-439A-9249-2D98149DAB81 wds:Q56873521-0DD70732-B55B-48FF-B928-C0B49D3CF9AB wds:Q56873521-0E1CA5A6-EE8D-47AA-8FD4-5DB81D0BBA37 wds:Q56873521-127AF24E-8191-4AF8-BCFB-4C1E5BDAA32E wds:Q56873521-2A92DD67-0782-45A6-8217-65F37FC86A3A wds:Q56873521-2E04D0E6-7CE3-481D-AB8C-C92CF7703AFF wds:Q56873521-36573AE0-C7C1-411E-A582-CED158B88D80 wds:Q56873521-42CAAA11-4BB2-4007-AECE-213C4E79EC0F wds:Q56873521-53FAF2C0-14A1-4F47-9454-C762EAD82167 wds:Q56873521-60F374D0-AD25-4FD9-8FD0-41CA6C5E24CB wds:Q56873521-6BED7F30-D0C2-4F6F-872F-D0BB4901FD8E wds:Q56873521-6DE5934B-D314-4402-AF5D-1151DDC64B89 wds:Q56873521-7D61903D-644C-4E7B-A702-1E08AA120EEC wds:Q56873521-BDBB79E3-9384-4492-A46B-4580C6F5BE5D wds:Q56873521-CE97FEBE-B388-4FBB-BDF6-BA7AB57C2A56 wds:Q56873521-D3EFB647-FB1F-4C3D-BE88-42ABFA6B50B7 wds:Q56873521-DD5CBAE2-1D8D-4656-9EFE-6D3AB44680E8 wds:Q56873521-FA19A0FD-9EE8-4BCA-87DE-09930D331C10 wds:Q56873521-FD421E22-88D2-4EF0-860E-B7CBFDFE7836 wds:Q56873521-FE107507-C818-41EA-8D64-A8545E49CED2
cites work	Insights into the function of Rim protein in photoreceptors and etiology of Stargardt's disease from the phenotype in abcr knockout mice The absence of c-fos prevents light-induced apoptotic cell death of photoreceptors in retinal degeneration in vivo Sunlight and age-related macular degeneration. The Beaver Dam Eye Study Abnormal photoresponses and light-induced apoptosis in rods lacking rhodopsin kinase Blue and ultraviolet light-absorbing opsin from the retinal pigment epithelium Retinal degeneration in transgenic mice with photoreceptor-specific expression of a dominant-negative fibroblast growth factor receptor. Retinopathy induced in mice by targeted disruption of the rhodopsin gene c-fos controls the "private pathway" of light-induced apoptosis of retinal photoreceptors Rpe65 is necessary for production of 11-cis-vitamin A in the retinal visual cycle. Disease sequence from mutant rhodopsin allele to rod and cone photoreceptor degeneration in man. Diurnal expression of c-fos in the mouse retina. Apoptotic cell death in retinal degenerations. Development and degeneration of retina in rds mutant mice: effects of light on the rate of degeneration in albino and pigmented homozygous and heterozygous mutant and normal mice Differential DNA binding activities of the transcription factors AP-1 and Oct-1 during light-induced apoptosis of photoreceptors Strain differences in sensitivity to light-induced photoreceptor degeneration in albino mice. Inhibition of cytochrome oxidase and blue-light damage in rat retina. Normal retina releases a diffusible factor stimulating cone survival in the retinal degeneration mouse RPE conditioned medium stimulates photoreceptor cell survival, neurite outgrowth and differentiation in vitro Light induces peroxidation in retina by activating prostaglandin G/H synthase. Artificial light and early-life exposure in age-related macular degeneration and in cataractogenic phototoxicity Observation of ultrastructural changes in cultured retinal pigment epithelium following exposure to blue light. Photoreceptor cell damage by light in young Royal College of Surgeons rats Neuron-specific enolase: a neuronal survival factor in the retinal extracellular matrix?
author name string	wds:Q56873521-3EDC7D89-B74F-4204-85EA-03029B1A46D4 wds:Q56873521-B778C014-5768-406F-A908-AD39A04FFA42 wds:Q56873521-FB522634-252B-4124-8AB7-5EDB2F303FFA
author name string	Andreas Wenzel Shirley Yu Charlotte E. Remé
rdfs:label	Protection of Rpe65-deficient mice identifies rhodopsin as a mediator of light-induced retinal degeneration (en) Protection of Rpe65-deficient mice identifies rhodopsin as a mediator of light-induced retinal degeneration (nl)
skos:prefLabel	Protection of Rpe65-deficient mice identifies rhodopsin as a mediator of light-induced retinal degeneration (en) Protection of Rpe65-deficient mice identifies rhodopsin as a mediator of light-induced retinal degeneration (nl)
name	Protection of Rpe65-deficient mice identifies rhodopsin as a mediator of light-induced retinal degeneration (en) Protection of Rpe65-deficient mice identifies rhodopsin as a mediator of light-induced retinal degeneration (nl)
author	wds:Q56873521-08FE0E0D-7E4D-4AC0-9A64-6FC6B1E27A9D wds:Q56873521-A06F0534-26D9-46DB-B20D-F7A338982177 wds:Q56873521-C21A7CE0-D037-42AC-AE63-10DF42290A25
author	Farhad Hafezi T. Michael Redmond Christian Grimm
title	wds:Q56873521-AC1130AB-5499-4D97-A805-57351A3CEC8C
title	Protection of Rpe65-deficient mice identifies rhodopsin as a mediator of light-induced retinal degeneration (en)
page(s)	wds:Q56873521-BFBE79FF-8F58-4D22-9EAC-203E27D48F00
page(s)	63-66
instance of	wds:Q56873521-AA34944C-F14D-4494-9174-F82F5CD91CBF
instance of	scholarly article
main subject	wds:Q56873521-62DAABE2-2413-4E77-9936-26766D33BD5B
main subject	retinal degeneration
PubMed ID	wds:Q56873521-C67B66CC-6FB1-4379-A759-16A707102A57
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/10802658
PubMed ID	10802658
published in	wds:Q56873521-B2564B9A-BFEE-43E3-AE31-8714B2DD70AD
published in	Nature Genetics
issue	wds:Q56873521-478B2A77-7C2F-426D-A37E-5F6C1D6042C5
volume	wds:Q56873521-8ED1200A-9F3F-4C56-83DB-20D0AF964E7A
issue	1
volume	25
DOI	wds:Q56873521-08778DB9-B64D-497E-8529-9DD5CEDC4562
DOI	http://dx.doi.org/10.1038/75614
DOI	10.1038/75614
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q56873521
is cites work of	Rpe65 Is a Retinyl Ester Binding Protein That Presents Insoluble Substrate to the Isomerase in Retinal Pigment Epithelial Cells Retinal compensatory changes after light damage in albino mice Neuroprotective role of erythropoietin by antiapoptosis in the retina.

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