About: Expedient synthesis and biological evaluation of alkenyl acyclic nucleoside phosphonate prodrugs

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About: Expedient synthesis and biological evaluation of alkenyl acyclic nucleoside phosphonate prodrugs Goto Sponge NotDistinct Permalink

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scholarly article by Elisa Pileggi published in July 2018

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в липні 2018 (uk) article scientifique publié en 2018 (fr) im Juli 2018 veröffentlichter wissenschaftlicher Artikel (de) scholarly article by Elisa Pileggi published in July 2018 (en)
publication date	wds:Q56763232-3EF60DF9-3D19-4B43-94F6-CC2D33AEA5A9
publication date	2018-07-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q56763232-D1E71A3A-2D91-40FC-9D8D-943F9939195E
language of work or name	English
cites work	wds:Q56763232-02DD1B72-50A0-4912-AEC7-3AC036A5768C wds:Q56763232-084FDF2C-4C3B-4274-A633-5CCBE8C89A76 wds:Q56763232-1140DE35-2CED-43C4-9C03-C6717B239ED8 wds:Q56763232-2888468F-B00D-4EA2-B6E3-3594495B9937 wds:Q56763232-48F3C005-11E9-4986-A814-4DC60EF3CB9E wds:Q56763232-4C44139F-52FB-4172-9D9E-0050041066A4 wds:Q56763232-4D9E298C-49C7-4793-BA0F-33735C3CEAD2 wds:Q56763232-529D8FD7-524B-48F1-872B-BC18BEE19426 wds:Q56763232-52C9CB27-A587-4D46-BA0E-EE01754073DE wds:Q56763232-5318C849-BEB2-496E-8ED1-5F98BF5456A0 wds:Q56763232-531CC398-2193-464E-B519-70AA1D28192F wds:Q56763232-66DC9428-1D19-4C08-B62B-EE528B8061C7 wds:Q56763232-725E14E3-9AA1-47DE-BAFB-B3657DC26082 wds:Q56763232-735316D5-754A-46FA-98B9-F2B920666167 wds:Q56763232-788B32F9-9ACD-49BB-9393-2557C0AE0AF6 wds:Q56763232-7A79EA29-D91E-4209-B1D7-7E65C9D08B3A wds:Q56763232-7DCAFC10-176C-47A4-894A-F46670E13C56 wds:Q56763232-865DE18D-5FC4-440D-A36B-53C0FB593ED4 wds:Q56763232-88753386-F9DA-46D8-9839-59B50E6B5109 wds:Q56763232-8A265B05-B9FA-4BAC-8094-42BDAA78D605 wds:Q56763232-8DCB0F3C-F329-44F0-BB9C-3894C56B510A wds:Q56763232-A13B1106-4ABD-4369-BFD2-ED600C31407B wds:Q56763232-AC620273-3CAE-41B0-959A-6C2B4594D225 wds:Q56763232-B23D9CD3-CF27-41C5-9A4F-7F6AD67A4924 wds:Q56763232-B36D4B02-1C5B-4C22-BD87-F1610C84B686 wds:Q56763232-B405C03E-2809-4DE3-A8FB-FF8D223EF61B wds:Q56763232-B8FDF01D-56BF-48AB-8F31-9A189B738893 wds:Q56763232-BDCE37D9-B8EC-429C-B19D-A607A59702A0 wds:Q56763232-C2789FEB-E05E-4DC4-A914-620168F74421 wds:Q56763232-C348304B-5B38-4273-954F-189E173741C5 wds:Q56763232-C7D1E66E-7F96-4ADE-B75A-9F298C659716 wds:Q56763232-CA46935B-D8A8-4660-B448-D839F6435BC7 wds:Q56763232-EB0E6201-83B4-48CC-90F2-51FCDBDBA476 wds:Q56763232-EB14369F-E947-418F-95CA-AE7F06FA4760 wds:Q56763232-EBB8E4D4-BDC5-48B1-A93B-9ED0CFD111D0 wds:Q56763232-EE276882-D32F-4A32-8BB7-0358A1E531FB wds:Q56763232-FA2D7B5C-30E8-4BF9-BAD7-C6B6773BCB8B wds:Q56763232-FBE6D71B-48E1-4B16-A11A-6C2BCE9F2462 wds:Q56763232-FEF059F2-157C-4F4F-B506-255FD6EDBBA6
cites work	Discovery of a β-d-2'-deoxy-2'-α-fluoro-2'-β-C-methyluridine nucleotide prodrug (PSI-7977) for the treatment of hepatitis C virus Synthesis of nucleoside phosphate and phosphonate prodrugs The efficacy and safety of tenofovir alafenamide versus tenofovir disoproxil fumarate in antiretroviral regimens for HIV-1 therapy: Meta-analysis A novel and efficient one-pot synthesis of symmetrical diamide (bis-amidate) prodrugs of acyclic nucleoside phosphonates and evaluation of their biological activities Acyclic nucleoside phosphonates: a key class of antiviral drugs Tenofovir alafenamide: A novel prodrug of tenofovir for the treatment of Human Immunodeficiency Virus Application of ProTide technology to gemcitabine: a successful approach to overcome the key cancer resistance mechanisms leads to a new agent (NUC-1031) in clinical development. The ProTide Prodrug Technology: From the Concept to the Clinic Kinetin Riboside and Its ProTides Activate the Parkinson's Disease Associated PTEN-Induced Putative Kinase 1 (PINK1) Independent of Mitochondrial Depolarization Kinase-independent phosphoramidate S1P1 receptor agonist benzyl ether derivatives. Phosphoramidate ProTides of the anticancer agent FUDR successfully deliver the preformed bioactive monophosphate in cells and confer advantage over the parent nucleoside Acyclic Nucleoside Phosphonates Containing 9-Deazahypoxanthine and a Five-Membered Heterocycle as Selective Inhibitors of Plasmodial 6-Oxopurine Phosphoribosyltransferases. Synthesis and evaluation of symmetric acyclic nucleoside bisphosphonates as inhibitors of the Plasmodium falciparum, Plasmodium vivax and human 6-oxopurine phosphoribosyltransferases and the antimalarial activity of their prodrugs Medicinal chemistry of nucleoside phosphonate prodrugs for antiviral therapy. Nucleoside Derived Antibiotics to Fight Microbial Drug Resistance: New Utilities for an Established Class of Drugs? The synthesis of tenofovir and its analogues via asymmetric transfer hydrogenation. Diversity-oriented synthesis of acyclic nucleosides via ring-opening of vinyl cyclopropanes with purines. Inhibition of hypoxanthine-guanine phosphoribosyltransferase by acyclic nucleoside phosphonates: a new class of antimalarial therapeutics Acyclic Immucillin Phosphonates: Second-Generation Inhibitors of Plasmodium falciparum Hypoxanthine- Guanine-Xanthine Phosphoribosyltransferase Tenofovir alafenamide for the treatment of chronic hepatitis B virus infection. Tenofovir Alafenamide: A Review in Chronic Hepatitis B. Phosphoramidates and phosphonamidates (ProTides) with antiviral activity Novel antiviral C5-substituted pyrimidine acyclic nucleoside phosphonates selected as human thymidylate kinase substrates First Crystal Structures of Mycobacterium tuberculosis 6-Oxopurine Phosphoribosyltransferase: Complexes with GMP and Pyrophosphate and with Acyclic Nucleoside Phosphonates Whose Prodrugs Have Antituberculosis Activity Synthesis and Evaluation of Novel Acyclic Nucleoside Phosphonates as Inhibitors of Plasmodium falciparum and Human 6-Oxopurine Phosphoribosyltransferases Bisamidate Prodrugs of 2-Substituted 9-[2-(Phosphonomethoxy)ethyl]adenine (PMEA, adefovir) as Selective Inhibitors of Adenylate Cyclase Toxin from Bordetella pertussis. Olefin cross-metathesis for the synthesis of alkenyl acyclonucleoside phosphonates A new strategy to construct acyclic nucleosides via Ag(I)-catalyzed addition of pronucleophiles to 9-allenyl-9H-purines. Sofosbuvir treatment and hepatitis C virus infection Design and Synthesis of Fluorescent Acyclic Nucleoside Phosphonates as Potent Inhibitors of Bacterial Adenylate Cyclases Tenofovir alafenamide fumarate for the treatment of HIV infection Phosphonoamidate prodrugs of C5-substituted pyrimidine acyclic nucleosides for antiviral therapy. Antimalarial activity of prodrugs of N-branched acyclic nucleoside phosphonate inhibitors of 6-oxopurine phosphoribosyltransferases PMPA and PMEA prodrugs for the treatment of HIV infections and human papillomavirus (HPV) associated neoplasia and cancer Synthesis and broad spectrum antiviral evaluation of bis(POM) prodrugs of novel acyclic nucleosides Oral Delivery of Propofol with Methoxymethylphosphonic Acid as the Delivery Vehicle. Highly convergent synthesis and antiviral activity of (E)-but-2-enyl nucleoside phosphonoamidates. Synthesis, X-ray crystal structural study, antiviral and cytostatic evaluations of the novel unsaturated acyclic and epoxide nucleoside analogues. The Preparation of Trisubstituted Alkenyl Nucleoside Phosphonates under Ultrasound-Assisted Olefin Cross-Metathesis
author name string	wds:Q56763232-303FD4FB-5D1E-4BAA-9D5F-6C746449F395 wds:Q56763232-3B2C330F-412D-4D20-B1DA-372CAE0220B4 wds:Q56763232-3ED56AA0-8FC8-436C-9550-06B9490AA552
author name string	Michaela Serpi Elisa Pileggi Fabrizio Pertusati
rdfs:label	Expedient synthesis and biological evaluation of alkenyl acyclic nucleoside phosphonate prodrugs (en) Expedient synthesis and biological evaluation of alkenyl acyclic nucleoside phosphonate prodrugs (nl)
skos:prefLabel	Expedient synthesis and biological evaluation of alkenyl acyclic nucleoside phosphonate prodrugs (en) Expedient synthesis and biological evaluation of alkenyl acyclic nucleoside phosphonate prodrugs (nl)
name	Expedient synthesis and biological evaluation of alkenyl acyclic nucleoside phosphonate prodrugs (en) Expedient synthesis and biological evaluation of alkenyl acyclic nucleoside phosphonate prodrugs (nl)

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