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article by Aaron Balog et al published December 1996 in Angewandte Chemie International Edition

Attributes	Values
rdf:type	Item
description	наукова стаття, опублікована в грудні 1996 (uk) article scientifique publié en 1996 (fr) im Dezember 1996 veröffentlichter wissenschaftlicher Artikel (de) article by Aaron Balog et al published December 1996 in Angewandte Chemie International Edition (en)
publication date	wds:Q56482594-15DABA8A-1888-4215-B34E-A150436D966C
publication date	1996-12-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q56482594-795C1D60-154E-4294-B91B-4589F9523046
language of work or name	English
cites work	wds:Q56482594-743C9915-2641-4978-B73E-5D86CA1A034B
cites work	Epothilone A and B—Novel 16-Membered Macrolides with Cytotoxic Activity: Isolation, Crystal Structure, and Conformation in Solution
author name string	wds:Q56482594-1470CBB2-676F-4B9D-9761-4AC405528D7B wds:Q56482594-5C22045D-3069-48B1-8D93-1D8175CC73A8 wds:Q56482594-86F78178-59BD-4269-8269-A5803F25974E wds:Q56482594-93510600-F95A-4C0E-9145-C4C500D4C320 wds:Q56482594-96387169-E055-463C-9304-7FAD2B88F9A8 wds:Q56482594-C5B689F6-C2CE-49E1-B194-A638AE124760 wds:Q56482594-F0EC7044-095A-44C0-97DA-7D3B995F87C7
author name string	Ted Kamenecka Aaron Balog Samuel J. Danishefsky Dongfang Meng Erik J. Sorensen Peter Bertinato Dai-Shi Su
rdfs:label	Total Synthesis of(–)-Epothilone A (en)
skos:prefLabel	Total Synthesis of(–)-Epothilone A (en)
name	Total Synthesis of(–)-Epothilone A (en)
title	wds:Q56482594-CDFDEE99-1F68-49E2-A6AB-28C589DB60DE
title	Total Synthesis of(–)-Epothilone A (en)
page(s)	wds:Q56482594-BEE8EFE9-25DB-4E3A-8D60-FEAC7A33C265
page(s)	2801-2803
instance of	wds:Q56482594-4FA6A729-6686-4448-97B3-97DA759ABE54
instance of	scholarly article
published in	wds:Q56482594-8ECA5F78-B4D2-4A7B-BA91-37E92BCD2CFD
published in	Angewandte Chemie International Edition
issue	wds:Q56482594-0B28150F-2E4F-4C48-A645-874D4F0F1C69
volume	wds:Q56482594-86FADA6F-D107-430C-9E48-F0BF331AC30A
issue	2324
volume	35
DOI	wds:Q56482594-D0CB1090-DA2E-454B-9623-24C165773186
DOI	http://dx.doi.org/10.1002/ANIE.199628011
DOI	10.1002/ANIE.199628011
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q56482594
is cites work of	Constructing molecular complexity and diversity: total synthesis of natural products of biological and medicinal importance Desoxyepothilone B is curative against human tumor xenografts that are refractory to paclitaxel. Therapeutic effect against human xenograft tumors in nude mice by the third generation microtubule stabilizing epothilones Cross-coupling reactions of organoboranes: an easy way to construct C-C bonds (Nobel Lecture). C6-C8 bridged epothilones: consequences of installing a conformational lock at the edge of the macrocycle. The chemistry and biology of epothilones--the wheel keeps turning. Synthesis of epothilones A and B in solid and solution phase The 12,13-diol cyclization approach for a truly stereocontrolled total synthesis of epothilone B and the synthesis of a conformationally restrained analogue Chemical synthesis and biological properties of pyridine epothilones Recent advances in the cross-coupling reactions of organoboron derivatives with organic electrophiles, 1995–1998 Cross-coupling Reactions of Organoboranes: An Easy Method for C–C Bonding RING-CLOSING METATHESIS STRATEGY TO UNSATURATED γ- AND δ-LACTONES: SYNTHESIS OF HYDROXYETHYLENE ISOSTERE FOR PROTEASE INHIBITORS. Alkyne metathesis: development of a novel molybdenum-based catalyst system and its application to the total synthesis of epothilone A and C. Total synthesis of epothilone E and related side-chain modified analogues via a Stille coupling based strategy Oxidative and reductive transformations of epothilone A Derivatization of the C12-C13 functional groups of epothilones A, B and C The synthesis, discovery, and development of a highly promising class of microtubule stabilization agents: curative effects of desoxyepothilones B and F against human tumor xenografts in nude mice Novel molecules that interact with microtubules and have functional activity similar to Taxol Desoxyepothilone B: an efficacious microtubule-targeted antitumor agent with a promising in vivo profile relative to epothilone B. Subcellular distribution of epothilones in human tumor cells Aldolase-catalyzed asymmetric synthesis of novel pyranose synthons as a new entry to heterocycles and epothilones Synthesis and biological evaluation of highly potent analogues of epothilones B and D. Heterologous expression of epothilone biosynthetic genes in Myxococcus xanthus The antibody catalysis route to the total synthesis of epothilones Synthesis and biological properties of C12,13-cyclopropyl-epothilone A and related epothilones. Current complexity: a tool for assessing the complexity of organic molecules. Convenient synthesis of novel macrocyclic urethanes: alkoxycarbonylation of amines and ring-closing metathesis strategy Myxobacterial bounty Macrolide Synthesis through Intramolecular Oxidative Cross-Coupling of Alkenes. Subtle Variations in the Long-Range Transmission of Stereochemical Information: Matched and Mismatched Aldol Reactions This work was supported by the National Institutes of Health (Grant Nos. CA-28824 and HL-25848) Total synthesis of epothilones A-F From EPOthilone to EPO: Aa challenge for natural product synthesis
is cites work of	wds:Q36861181-BCC81B8B-F80E-4D1A-9D03-B5CEA72D313B wds:Q36271699-2341AB57-9EE7-47A4-9922-ED79782E023D wds:Q43644646-1125B191-969C-4A7D-AE33-3A0E2DCB14BF wds:Q92714475-7AEF53BD-6E3A-4095-864F-7A837475F3D5 wds:Q24536090-E88F120C-B3CD-4DAB-BBA0-EAF1E4105401 wds:Q33944889-78B9F100-17EF-43AB-B821-D7ED0300B128 wds:Q34432179-4D4465C4-6BA5-4DB7-B0A5-8EC2BD470618 wds:Q36186718-09B6611C-A340-4BC9-934F-55E7324E43C2 wds:Q60085443-0D614846-442F-4741-9119-0A9066DA11F9 wds:Q73117539-B8D7211C-2899-4E31-9CB5-9B8C3CE7141F wds:Q36861548-6EF01E31-35AE-46B5-A328-1353557654ED wds:Q48538946-B9071EE5-AF1A-43AB-9C8E-EC24A482FB72 wds:Q53510685-0A4203DE-FA30-4F37-9C91-F3EECE401898 wds:Q57713739-39298810-0F96-4EEA-ADA7-F84CC838EB77 wds:Q33614661-84F7D21D-4E3E-45E1-ABFB-FC1FA0D7891D wds:Q36541279-8EDEBB33-4FA7-47A0-B44E-4AB01D99EED6 wds:Q35642476-6174BFA0-04E1-4AEE-BFFE-D58B3E9DB2EA wds:Q77749663-71ABF7C2-2E8A-4E95-AA94-F914AF5A109E wds:Q95346727-ADA9A9C6-CE32-40E5-B074-FC7CEF5A9B43 wds:Q30731243-C649FCC9-7233-4C15-B319-15B5A77FF409 wds:Q34112205-6C412F91-2498-4E9C-BB30-97A5DB065181 wds:Q36752835-94B1CB31-1F6D-4CA8-AD8F-890E290724B9 wds:Q54025270-B533823F-F1B6-4EA2-8B4F-31062CF57417 wds:Q77749658-377CAAAE-9D63-438A-8255-BD42127F6B74

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