About: chronic idiopathic myelofibrosis

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An Entity of Type : wikibase:Item, within Data Space : wikidata.demo.openlinksw.com associated with source document(s)

Attributes	Values
rdf:type	Item
description	Krankheit (de) хвороба (uk) malattia cronica del midollo osseo (it)
rdfs:label	chronic idiopathic myelofibrosis (en) Mielofibrose idiopática (pt) kronična idiopatska mielofibroza (sl) mielofibrosi idiopatica cronica (it) mielofibrosis idiopática crónica (es) myélofibrose primitive (fr) primary myelofibrosis (nl)
skos:prefLabel	chronic idiopathic myelofibrosis (en) Mielofibrose idiopática (pt) kronična idiopatska mielofibroza (sl) mielofibrosi idiopatica cronica (it) mielofibrosis idiopática crónica (es) myélofibrose primitive (fr) primary myelofibrosis (nl)
name	chronic idiopathic myelofibrosis (en) Mielofibrose idiopática (pt) kronična idiopatska mielofibroza (sl) mielofibrosi idiopatica cronica (it) mielofibrosis idiopática crónica (es) myélofibrose primitive (fr) primary myelofibrosis (nl)
instance of	wds:Q3857106-abf01f2d-491c-de21-0110-0e2015645b43
instance of	disease
subclass of	wds:Q3857106-7bf93e75-4fdd-62a0-3ede-3a91fa5d1bed
subclass of	myelofibrosis
Google Knowledge Graph ID	wds:Q3857106-28E1BD9C-32B1-4832-B7F2-B9A54C9510D2
Google Knowledge Graph ID	http://g.co/kg/g/1q6h_y5bv
Google Knowledge Graph ID	/g/1q6h_y5bv
Genetics Home Reference Conditions ID	wds:Q3857106-949F48AC-AC3D-451D-A50A-23EA4695C6AD
Genetics Home Reference Conditions ID	primary-myelofibrosis
skos:altLabel	primary myelofibrosis (en) Metaplasia mieloide agnogenica (it) Mielofibrosi con metaplasia mieloide (it) Mielofibrosi primitiva (it) mielofibrosis primaria (es) mielofibrosis primitiva (es) primarna mielofibroza (sl)
NCI Thesaurus ID	wds:Q3857106-4B943BDD-C528-40C2-8654-971BCEA3E758
UMLS CUI	wds:Q3857106-8837316b-4713-998f-e8cc-b592f50b49b8
NCI Thesaurus ID	C2862
UMLS CUI	C0001815
is owl:sameAs of	chronic idiopathic myelofibrosis
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q3857106 https://it.wikipedia.org/wiki/Mielofibrosi_idiopatica_cronica https://pt.wikipedia.org/wiki/Mielofibrose_idiop%C3%A1tica
is subclass of of	cellular phase chronic idiopathic myelofibrosis myeloid metaplasia familial myelofibrosis
is subclass of of	wds:Q18557834-C92019DD-0F09-4726-9F7A-52138335E1DE wds:Q55012637-3096b75a-463a-0112-e5e3-320d6efb5543 wds:Q55790223-609adf71-47c1-cdfe-fefa-ad9167ca04b0
is main subject of	New prognostic scoring system for primary myelofibrosis based on a study of the International Working Group for Myelofibrosis Research and Treatment Mesenchymal stem cells from JAK2V617F mutant patients with primary myelofibrosis do not harbor JAK2 mutant allele CD146(+) bone marrow osteoprogenitors increase in the advanced stages of primary myelofibrosis Allogeneic hemopoietic SCT for patients with primary myelofibrosis: a predictive transplant score based on transfusion requirement, spleen size and donor type. Refined cytogenetic-risk categorization for overall and leukemia-free survival in primary myelofibrosis: a single center study of 433 patients Primary myelofibrosis: update on definition, pathogenesis, and treatment. Erythropoiesis stimulating agents have limited therapeutic activity in transfusion-dependent patients with primary myelofibrosis regardless of serum erythropoietin level. Primary myelofibrosis: 2014 update on diagnosis, risk-stratification, and management. Impact of ruxolitinib on the natural history of primary myelofibrosis: a comparison of the DIPSS and the COMFORT-2 cohorts. The number of prognostically detrimental mutations and prognosis in primary myelofibrosis: an international study of 797 patients A dynamic prognostic model to predict survival in primary myelofibrosis: a study by the IWG-MRT (International Working Group for Myeloproliferative Neoplasms Research and Treatment). Identification during the follow-up of time-dependent prognostic factors for the competing risks of death and blast phase in primary myelofibrosis: a study of 172 patients Hematopathologic findings in chronic idiopathic myelofibrosis Is it Primary Myelofibrosis or Chronic Lymphocytic Leukemia Related Secondary Myelofibrosis? Evolution of myelofibrosis in chronic idiopathic myelofibrosis as evidenced in sequential bone marrow biopsy specimens Grade of bone marrow fibrosis is associated with relevant hematological findings-a clinicopathological study on 865 patients with chronic idiopathic myelofibrosis Allogeneic marrow transplantation for primary myelofibrosis and myelofibrosis secondary to polycythaemia vera or essential thrombocytosis Pathological interactions between hematopoietic stem cells and their niche revealed by mouse models of primary myelofibrosis Bone morphogenetic proteins are overexpressed in the bone marrow of primary myelofibrosis and are apparently induced by fibrogenic cytokines Prognostic implications of the European consensus for grading of bone marrow fibrosis in chronic idiopathic myelofibrosis The relationship of the active and latent forms of TGF-β1 with marrow fibrosis in essential thrombocythemia and primary myelofibrosis Identification of patients with poorer survival in primary myelofibrosis based on the burden of JAK2V617F mutated allele DIPSS plus: a refined Dynamic International Prognostic Scoring System for primary myelofibrosis that incorporates prognostic information from karyotype, platelet count, and transfusion status DNMT3A mutational analysis in primary myelofibrosis, chronic myelomonocytic leukemia and advanced phases of myeloproliferative neoplasms SRSF2 and U2AF1 mutations in primary myelofibrosis are associated with JAK2 and MPL but not calreticulin mutation and may independently reoccur after allogeneic stem cell transplantation U2AF1 mutations in primary myelofibrosis are strongly associated with anemia and thrombocytopenia despite clustering with JAK2V617F and normal karyotype. The dawn of targeted therapy for primary myelofibrosis: opportunities and challenges Low JAK2V617F allele burden in primary myelofibrosis, compared to either a higher allele burden or unmutated status, is associated with inferior overall and leukemia-free survival Monosomal karyotype in primary myelofibrosis is detrimental to both overall and leukemia-free survival SRSF2 mutations in primary myelofibrosis: significant clustering with IDH mutations and independent association with inferior overall and leukemia-free survival Increased angiogenesis in chronic idiopathic myelofibrosis: vascular endothelial growth factor as a prominent angiogenic factor. Circulating interleukin (IL)-8, IL-2R, IL-12, and IL-15 levels are independently prognostic in primary myelofibrosis: a comprehensive cytokine profiling study Thrombospondin-1 (TSP-1) in primary myelofibrosis (PMF) - a megakaryocyte-derived biomarker which largely discriminates PMF from essential thrombocythemia Aberrant collagenase expression in chronic idiopathic myelofibrosis is related to the stage of disease but not to the JAK2 mutation status European Bone Marrow Working Group trial on reproducibility of World Health Organization criteria to discriminate essential thrombocythemia from prefibrotic primary myelofibrosis The Thr224Asn mutation in the VPS45 gene is associated with the congenital neutropenia and primary myelofibrosis of infancy A phase I study of panobinostat (LBH589) in patients with primary myelofibrosis (PMF) and post-polycythaemia vera/essential thrombocythaemia myelofibrosis (post-PV/ET MF). Phase II trial of panobinostat, an oral pan-deacetylase inhibitor in patients with primary myelofibrosis, post-essential thrombocythaemia, and post-polycythaemia vera myelofibrosis Clinical effect of driver mutations of JAK2, CALR, or MPL in primary myelofibrosis A phase II study of vorinostat (MK-0683) in patients with primary myelofibrosis and post-polycythemia vera myelofibrosis SETBP1 mutations in 415 patients with primary myelofibrosis or chronic myelomonocytic leukemia: independent prognostic impact in CMML. The presence of JAK2V617F in primary myelofibrosis or its allele burden in polycythemia vera predicts chemosensitivity to hydroxyurea Type 1 vs type 2 calreticulin mutations in primary myelofibrosis: differences in phenotype and prognostic impact. TP53 mutations and polymorphisms in primary myelofibrosis TP53 mutation is rare in primary myelofibrosis

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