About: Exploiting the selectivity of protein phosphatase 1 for pharmacological intervention

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About: Exploiting the selectivity of protein phosphatase 1 for pharmacological intervention Goto Sponge NotDistinct Permalink

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scientific article published on 14 March 2012

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rdf:type	Item
description	videnskabelig artikel (da) article científic (ca) articol științific (ro) articolo scientifico (it) artigo científico (gl) artigo científico (pt) artigo científico (pt-br) artikull shkencor (sq) artículo científico (es) bilimsel makale (tr) scienca artikolo (eo) vedecký článok (sk) vetenskaplig artikel (sv) vitenskapelig artikkel (nb) vitskapeleg artikkel (nn) vědecký článek (cs) wetenschappelijk artikel (nl) wissenschaftlicher Artikel (de) научная статья (ru) научни чланак (sr) מאמר מדעי (he) artikel ilmiah (id) bài báo khoa học (vi) article scientifique (fr) বৈজ্ঞানিক নিবন্ধ (bn) artículu científicu espublizáu en 2012 (ast) наукова стаття, опублікована в березні 2012 (uk) scientific article published on 14 March 2012 (en) scientific article published on 14 March 2012 (en-ca) scientific article published on 14 March 2012 (en-gb) مقالة علمية نشرت في 14 مارس 2012 (ar)
publication date	wds:Q37984815-70383819-C3DF-48F5-B40A-A5DF9F9573CA
publication date	2012-03-14 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q37984815-4220E558-42EB-44B2-BB36-D1A54E3B6AC4
language of work or name	English
cites work	wds:Q37984815-1BA54083-B969-44D8-AB9C-0190025D2EC4 wds:Q37984815-1E52B94D-3D01-4B00-98A8-6E7CD1872334 wds:Q37984815-241F2636-5774-42A2-BB82-E06D01037ECD wds:Q37984815-3B1CA6A6-A670-42DC-902A-975C015A25F3 wds:Q37984815-5349DE12-7347-4F8B-832C-6F62905509C5 wds:Q37984815-6450D1BD-AA69-459B-A9FB-3EC5FAFD8DE0 wds:Q37984815-74CF2893-479D-4472-AE0B-01130883BA40 wds:Q37984815-799F869E-87C8-4D29-B444-7197B6DAAC0C wds:Q37984815-7CF5777A-8F20-458A-9602-A1B13ED6024F wds:Q37984815-7D5AE447-0D7F-43FC-BCAC-EA6A958FC5F0 wds:Q37984815-84279781-23D4-4F7E-AAF1-FB7194B2854C wds:Q37984815-84DB57B7-D384-40DB-A07E-AFCC2B0AD2EC wds:Q37984815-8633D53A-32D3-40EA-AEEA-830367C79238 wds:Q37984815-8BC48252-7186-41B5-BB25-B17E9FDBA108 wds:Q37984815-97F5FDA6-5167-4128-81D8-DCBA78B84C19 wds:Q37984815-991C4939-4E36-4D8D-9E6A-00F4A90A2F94 wds:Q37984815-AF6EAB91-9FE4-4D31-9017-AB1FE92D9F20 wds:Q37984815-B33071DC-43A6-4C56-A6F3-EA374DD1888C wds:Q37984815-BB5BB724-4C3D-409B-B72E-083BF895A490 wds:Q37984815-BF90F0D2-9FDD-4DF9-A09E-346EB00BE8FB wds:Q37984815-E3341C95-8083-4DF8-A020-59A88EA24763 wds:Q37984815-EC835322-BC18-473A-8099-39A02852BD4C wds:Q37984815-F3CB45C2-7D95-445F-9033-6E8C33228E4E
cites work	The substrate of Greatwall kinase, Arpp19, controls mitosis by inhibiting protein phosphatase 2A Greatwall phosphorylates an inhibitor of protein phosphatase 2A that is essential for mitosis The protein kinase complement of the human genome The extended PP1 toolkit: designed to create specificity Growth arrest and DNA damage-inducible protein GADD34 assembles a novel signaling complex containing protein phosphatase 1 and inhibitor 1. Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alpha CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities From promiscuity to precision: protein phosphatases get a makeover Targeting protein serine/threonine phosphatases for drug development A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress Selective inhibition of a regulatory subunit of protein phosphatase 1 restores proteostasis Inhibition of a constitutive translation initiation factor 2alpha phosphatase, CReP, promotes survival of stressed cells Orchestrating the unfolded protein response in health and disease Deactylase inhibitors disrupt cellular complexes containing protein phosphatases and deacetylases Emerging roles of nuclear protein phosphatases Ppp1r15 gene knockout reveals an essential role for translation initiation factor 2 alpha (eIF2alpha) dephosphorylation in mammalian development Stress-induced gene expression requires programmed recovery from translational repression Crystal structure of calcineurin-cyclophilin-cyclosporin shows common but distinct recognition of immunophilin-drug complexes An upstream open reading frame regulates translation of GADD34 during cellular stresses that induce eIF2alpha phosphorylation Regulation of cellular protein phosphatase-1 (PP1) by phosphorylation of the CPI-17 family, C-kinase-activated PP1 inhibitors Antihypertensive drug guanabenz is active in vivo against both yeast and mammalian prions Guanabenz. A review of its pharmacodynamic properties and therapeutic efficacy in hypertension
author name string	wds:Q37984815-290A114A-4858-4E61-A4CE-42709F71C538
author name string	Pavel Tsaytler
rdfs:label	Exploiting the selectivity of protein phosphatase 1 for pharmacological intervention (en) Exploiting the selectivity of protein phosphatase 1 for pharmacological intervention (nl) Exploiting the selectivity of protein phosphatase 1 for pharmacological intervention (ast)
skos:prefLabel	Exploiting the selectivity of protein phosphatase 1 for pharmacological intervention (en) Exploiting the selectivity of protein phosphatase 1 for pharmacological intervention (nl) Exploiting the selectivity of protein phosphatase 1 for pharmacological intervention (ast)
name	Exploiting the selectivity of protein phosphatase 1 for pharmacological intervention (en) Exploiting the selectivity of protein phosphatase 1 for pharmacological intervention (nl) Exploiting the selectivity of protein phosphatase 1 for pharmacological intervention (ast)
author	wds:Q37984815-10833AB0-A9D9-4360-9A28-97EBF350B19A
author	Anne Bertolotti
title	wds:Q37984815-062A8D1B-B566-497F-8BFE-F2D2E0C7D6E4
title	Exploiting the selectivity of protein phosphatase 1 for pharmacological intervention (en)
page(s)	wds:Q37984815-9D82672D-2C93-4B92-AE48-D3A1789649C7
page(s)	766-770
instance of	wds:Q37984815-681D524A-8746-4245-BD49-E1426667F19E

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